Addition of positive charges at the C-terminal peptide region of CssII, a mammalian scorpion peptide toxin, improves its affinity for sodium channels Nav1.6

Peptides

Volumn 32, Issue 1, 2011, Pages 75-79

  Estrada, Georgina ^a   Restano Cassulini, Rita ^a   Ortiz, Ernesto ^a   Possani, Lourival D ^a   Corzo, Gerardo ^a  

^a INSTITUTO DE BIOTECNOLOGÍA   (Mexico)

Author keywords

Centruroides suffusus suffusus; Expression; Peptide toxin; Protein folding; Recombinant; Scorpion

Indexed keywords

ASPARAGINE; PROTEIN CSS2; SCORPION VENOM; SODIUM CHANNEL NAV1.6; THREONINE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL LINE; CIRCULAR DICHROISM; ELECTROPHYSIOLOGY; IN VITRO STUDY; MOLECULAR CLONING; MOLECULAR INTERACTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECONDARY STRUCTURE; PROTEIN STRUCTURE; SODIUM CURRENT;

AMINO ACID SEQUENCE; ANIMALS; HUMANS; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; PROTEIN STRUCTURE, SECONDARY; SCORPION VENOMS; SCORPIONS; SODIUM CHANNELS;

BACTERIA (MICROORGANISMS); CENTRUROIDES SUFFUSUS SUFFUSUS; MAMMALIA; SCORPIONES;

EID: 78650522482     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2010.11.001     Document Type: Article

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