메뉴 건너뛰기




Volumn 34, Issue 38, 2013, Pages 10143-10150

Porous chitosan-hyaluronic acid scaffolds as a mimic of glioblastoma microenvironment ECM

Author keywords

Cancer stem cell; Glioma; Invasion; Multidrug resistance; Spheroid

Indexed keywords

CANCER STEM CELLS; GLIOMA; INVASION; MULTIDRUG RESISTANCE; SPHEROID;

EID: 84885372193     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.09.034     Document Type: Article
Times cited : (184)

References (66)
  • 2
    • 0034612289 scopus 로고    scopus 로고
    • Glioblastoma multiforme: the terminator
    • Holland E.C. Glioblastoma multiforme: the terminator. Proc Natl Acad Sci U S A 2000, 97:6242-6244.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 6242-6244
    • Holland, E.C.1
  • 4
    • 79952392467 scopus 로고    scopus 로고
    • Why don't we get more cancer? a proposed role of the microenvironment in restraining cancer progression
    • Bissell M.J., Hines W.C. Why don't we get more cancer? a proposed role of the microenvironment in restraining cancer progression. Nat Med 2011, 17:320-329.
    • (2011) Nat Med , vol.17 , pp. 320-329
    • Bissell, M.J.1    Hines, W.C.2
  • 5
    • 75749158184 scopus 로고    scopus 로고
    • Biomaterials offer cancer research the third dimension
    • Hutmacher D.W. Biomaterials offer cancer research the third dimension. Nat Mater 2010, 9:90-93.
    • (2010) Nat Mater , vol.9 , pp. 90-93
    • Hutmacher, D.W.1
  • 7
    • 84873248433 scopus 로고    scopus 로고
    • Invitro three-dimensional (3D) models in cancer research: an update
    • Kimlin L.C., Casagrande G., Virador V.M. Invitro three-dimensional (3D) models in cancer research: an update. Mol Carcinog 2013, 52:167-182.
    • (2013) Mol Carcinog , vol.52 , pp. 167-182
    • Kimlin, L.C.1    Casagrande, G.2    Virador, V.M.3
  • 8
    • 69249233604 scopus 로고    scopus 로고
    • Advancing science and technology via 3D culture on basement membrane matrix
    • Benton G., George J., Kleinman H.K., Arnaoutova I.P. Advancing science and technology via 3D culture on basement membrane matrix. JCell Physiol 2009, 221:18-25.
    • (2009) JCell Physiol , vol.221 , pp. 18-25
    • Benton, G.1    George, J.2    Kleinman, H.K.3    Arnaoutova, I.P.4
  • 9
    • 79951979275 scopus 로고    scopus 로고
    • Multiple uses of basement membrane-like matrix (BME/Matrigel) invitro and invivo with cancer cells
    • Benton G., Kleinman H.K., George J., Arnaoutova I. Multiple uses of basement membrane-like matrix (BME/Matrigel) invitro and invivo with cancer cells. Int J Cancer 2011, 128:1751-1757.
    • (2011) Int J Cancer , vol.128 , pp. 1751-1757
    • Benton, G.1    Kleinman, H.K.2    George, J.3    Arnaoutova, I.4
  • 14
    • 77953081587 scopus 로고    scopus 로고
    • Chitosan-alginate 3D scaffolds as a mimic of the glioma tumor microenvironment
    • Kievit F.M., Florczyk S.J., Veiseh O., Park J.O., Disis M.L., Zhang M. Chitosan-alginate 3D scaffolds as a mimic of the glioma tumor microenvironment. Biomaterials 2010, 31:5903-5910.
    • (2010) Biomaterials , vol.31 , pp. 5903-5910
    • Kievit, F.M.1    Florczyk, S.J.2    Veiseh, O.3    Park, J.O.4    Disis, M.L.5    Zhang, M.6
  • 15
    • 23744449992 scopus 로고    scopus 로고
    • Matrigel: basement membrane matrix with biological activity
    • Kleinman H.K., Martin G.R. Matrigel: basement membrane matrix with biological activity. Semin Cancer Biol 2005, 15:378-386.
    • (2005) Semin Cancer Biol , vol.15 , pp. 378-386
    • Kleinman, H.K.1    Martin, G.R.2
  • 16
    • 0026652062 scopus 로고
    • Supramolecular organization of extracellular matrix glycosaminoglycans, invitro and in the tissues
    • Scott J.E. Supramolecular organization of extracellular matrix glycosaminoglycans, invitro and in the tissues. FASEB J 1992, 6:2639-2645.
    • (1992) FASEB J , vol.6 , pp. 2639-2645
    • Scott, J.E.1
  • 17
    • 3042697038 scopus 로고    scopus 로고
    • Hyaluronan: from extracellular glue to pericellular cue
    • Toole B.P. Hyaluronan: from extracellular glue to pericellular cue. Nat Rev Cancer 2004, 4:528-539.
    • (2004) Nat Rev Cancer , vol.4 , pp. 528-539
    • Toole, B.P.1
  • 18
    • 39649085823 scopus 로고    scopus 로고
    • Main properties and current applications of some polysaccharides as biomaterials
    • Rinaudo M. Main properties and current applications of some polysaccharides as biomaterials. Polym Int 2008, 57:397-430.
    • (2008) Polym Int , vol.57 , pp. 397-430
    • Rinaudo, M.1
  • 19
    • 78650519154 scopus 로고    scopus 로고
    • Chitosan composites with inorganics, morphogenetic proteins and stem cells, for bone regeneration
    • Muzzarelli R.A.A. Chitosan composites with inorganics, morphogenetic proteins and stem cells, for bone regeneration. Carbohydr Polym 2011, 83:1433-1445.
    • (2011) Carbohydr Polym , vol.83 , pp. 1433-1445
    • Muzzarelli, R.A.A.1
  • 20
    • 79955673207 scopus 로고    scopus 로고
    • Chemical modifications of hyaluronic acid for the synthesis of derivatives for a broad range of biomedical applications
    • Schanté C.E., Zuber G., Herlin C., Vandamme T.F. Chemical modifications of hyaluronic acid for the synthesis of derivatives for a broad range of biomedical applications. Carbohydr Polym 2011, 85:469-489.
    • (2011) Carbohydr Polym , vol.85 , pp. 469-489
    • Schanté, C.E.1    Zuber, G.2    Herlin, C.3    Vandamme, T.F.4
  • 22
    • 73349134974 scopus 로고    scopus 로고
    • Hyaluronan-CD44 interactions in cancer: paradoxes and possibilities
    • Toole B.P. Hyaluronan-CD44 interactions in cancer: paradoxes and possibilities. Clin Cancer Res 2009, 15:7462-7468.
    • (2009) Clin Cancer Res , vol.15 , pp. 7462-7468
    • Toole, B.P.1
  • 23
    • 79953753019 scopus 로고    scopus 로고
    • Hyaluronan metabolism in remodeling extracellular matrix: probes for imaging and therapy of breast cancer
    • Veiseh M., Turley E.A. Hyaluronan metabolism in remodeling extracellular matrix: probes for imaging and therapy of breast cancer. Integr Biol 2011, 3:304-315.
    • (2011) Integr Biol , vol.3 , pp. 304-315
    • Veiseh, M.1    Turley, E.A.2
  • 24
    • 44749091840 scopus 로고    scopus 로고
    • Involvement of CD44, a molecule with a thousand faces, in cancer dissemination
    • Naor D., Wallach-Dayan S.B., Zahalka M.A., Sionov R.V. Involvement of CD44, a molecule with a thousand faces, in cancer dissemination. Semin Cancer Biol 2008, 18:260-267.
    • (2008) Semin Cancer Biol , vol.18 , pp. 260-267
    • Naor, D.1    Wallach-Dayan, S.B.2    Zahalka, M.A.3    Sionov, R.V.4
  • 25
    • 84860863436 scopus 로고    scopus 로고
    • Hyaluronic acid-based scaffold for central neural tissue engineering
    • Wang X.M., He J., Wang Y., Cui F.Z. Hyaluronic acid-based scaffold for central neural tissue engineering. Interface Focus 2012, 2:278-291.
    • (2012) Interface Focus , vol.2 , pp. 278-291
    • Wang, X.M.1    He, J.2    Wang, Y.3    Cui, F.Z.4
  • 26
    • 0346724871 scopus 로고    scopus 로고
    • Structure and interactions in chitosan hydrogels formed by complexation or aggregation for biomedical applications
    • Berger J., Reist M., Mayer J.M., Felt O., Gurny R. Structure and interactions in chitosan hydrogels formed by complexation or aggregation for biomedical applications. Eur J Pharm Biopharm 2004, 57:35-52.
    • (2004) Eur J Pharm Biopharm , vol.57 , pp. 35-52
    • Berger, J.1    Reist, M.2    Mayer, J.M.3    Felt, O.4    Gurny, R.5
  • 27
    • 37749024921 scopus 로고    scopus 로고
    • Properties and degradation of selected polysaccharides: hyaluronan and chitosan
    • Rinaudo M. Properties and degradation of selected polysaccharides: hyaluronan and chitosan. Corros Eng Sci Technol 2007, 42:324-334.
    • (2007) Corros Eng Sci Technol , vol.42 , pp. 324-334
    • Rinaudo, M.1
  • 28
    • 60849104777 scopus 로고    scopus 로고
    • Injectable in situ forming biodegradable chitosan-hyaluronic acid based hydrogels for cartilage tissue engineering
    • Tan H., Chu C.R., Payne K.A., Marra K.G. Injectable in situ forming biodegradable chitosan-hyaluronic acid based hydrogels for cartilage tissue engineering. Biomaterials 2009, 30:2499-2506.
    • (2009) Biomaterials , vol.30 , pp. 2499-2506
    • Tan, H.1    Chu, C.R.2    Payne, K.A.3    Marra, K.G.4
  • 29
    • 77956412459 scopus 로고    scopus 로고
    • Injectable in situ forming biodegradable chitosan-hyaluronic acid based hydrogels for adipose tissue regeneration
    • Tan H., Rubin J.P., Marra K.G. Injectable in situ forming biodegradable chitosan-hyaluronic acid based hydrogels for adipose tissue regeneration. Organogenesis 2010, 6:173-180.
    • (2010) Organogenesis , vol.6 , pp. 173-180
    • Tan, H.1    Rubin, J.P.2    Marra, K.G.3
  • 30
    • 80052288547 scopus 로고    scopus 로고
    • Sodium hyaluronate/chitosan polyelectrolyte complex scaffolds for dental pulp regeneration: synthesis and characterization
    • Coimbra P., Alves P., Valente T.A.M., Santos R., Correia I.J., Ferreira P. Sodium hyaluronate/chitosan polyelectrolyte complex scaffolds for dental pulp regeneration: synthesis and characterization. Int J Biol Macromol 2011, 49:573-579.
    • (2011) Int J Biol Macromol , vol.49 , pp. 573-579
    • Coimbra, P.1    Alves, P.2    Valente, T.A.M.3    Santos, R.4    Correia, I.J.5    Ferreira, P.6
  • 32
    • 80053603001 scopus 로고    scopus 로고
    • Amultifunctional 3D co-culture system for studies of mammary tissue morphogenesis and stem cell biology
    • Campbell J.J., Davidenko N., Caffarel M.M., Cameron R.E., Watson C.J. Amultifunctional 3D co-culture system for studies of mammary tissue morphogenesis and stem cell biology. PLoS One 2011, 6:e25661.
    • (2011) PLoS One , vol.6
    • Campbell, J.J.1    Davidenko, N.2    Caffarel, M.M.3    Cameron, R.E.4    Watson, C.J.5
  • 33
    • 77955466694 scopus 로고    scopus 로고
    • Chitosan-alginate scaffold culture system for hepatocellular carcinoma increases malignancy and drug resistance
    • Leung M., Kievit F.M., Florczyk S.J., Veiseh O., Wu J., Park J.O., et al. Chitosan-alginate scaffold culture system for hepatocellular carcinoma increases malignancy and drug resistance. Pharm Res 2010, 27:1939-1948.
    • (2010) Pharm Res , vol.27 , pp. 1939-1948
    • Leung, M.1    Kievit, F.M.2    Florczyk, S.J.3    Veiseh, O.4    Wu, J.5    Park, J.O.6
  • 34
    • 84876750358 scopus 로고    scopus 로고
    • 3D porous chitosan-alginate scaffolds: a new matrix for studying prostate cancer cell-lymphocyte interactions invitro
    • Florczyk S.J., Liu G., Kievit F.M., Lewis A.M., Wu J.D., Zhang M. 3D porous chitosan-alginate scaffolds: a new matrix for studying prostate cancer cell-lymphocyte interactions invitro. Adv Healthc Mater 2012, 1:590-599.
    • (2012) Adv Healthc Mater , vol.1 , pp. 590-599
    • Florczyk, S.J.1    Liu, G.2    Kievit, F.M.3    Lewis, A.M.4    Wu, J.D.5    Zhang, M.6
  • 35
    • 62549126037 scopus 로고    scopus 로고
    • Design and evaluation of a nano-scale differential tensile test device for nanofibers
    • Edmondson D., Bhattarai N., Jana S., Kim A., Zhang M. Design and evaluation of a nano-scale differential tensile test device for nanofibers. Appl Phys Lett 2009, 94:103101.
    • (2009) Appl Phys Lett , vol.94 , pp. 103101
    • Edmondson, D.1    Bhattarai, N.2    Jana, S.3    Kim, A.4    Zhang, M.5
  • 36
    • 67649935716 scopus 로고    scopus 로고
    • Microglial cell migration stimulated by ATP and C5a involve distinct molecular mechanisms: quantification of migration by a novel near-infrared method
    • Miller A.M., Stella N. Microglial cell migration stimulated by ATP and C5a involve distinct molecular mechanisms: quantification of migration by a novel near-infrared method. Glia 2009, 57:875-883.
    • (2009) Glia , vol.57 , pp. 875-883
    • Miller, A.M.1    Stella, N.2
  • 39
    • 80051821707 scopus 로고    scopus 로고
    • Elucidating the mechanobiology of malignant brain tumors using a brain matrix-mimetic hyaluronic acid hydrogel platform
    • Ananthanarayanan B., Kim Y., Kumar S. Elucidating the mechanobiology of malignant brain tumors using a brain matrix-mimetic hyaluronic acid hydrogel platform. Biomaterials 2011, 32:7913-7923.
    • (2011) Biomaterials , vol.32 , pp. 7913-7923
    • Ananthanarayanan, B.1    Kim, Y.2    Kumar, S.3
  • 40
    • 0028136623 scopus 로고
    • CD44 mediates human glioma cell adhesion and invasion invitro
    • Merzak A., Koocheckpour S., Pilkington G.J. CD44 mediates human glioma cell adhesion and invasion invitro. Cancer Res 1994, 54:3988-3992.
    • (1994) Cancer Res , vol.54 , pp. 3988-3992
    • Merzak, A.1    Koocheckpour, S.2    Pilkington, G.J.3
  • 41
    • 78649986150 scopus 로고    scopus 로고
    • TGF-beta receptor inhibitors target the CD44(high)/Id1(high) glioma-initiating cell population in human glioblastoma
    • Anido J., Saez-Borderias A., Gonzalez-Junca A., Rodon L., Folch G., Carmona M.A., et al. TGF-beta receptor inhibitors target the CD44(high)/Id1(high) glioma-initiating cell population in human glioblastoma. Cancer Cell 2010, 18:655-668.
    • (2010) Cancer Cell , vol.18 , pp. 655-668
    • Anido, J.1    Saez-Borderias, A.2    Gonzalez-Junca, A.3    Rodon, L.4    Folch, G.5    Carmona, M.A.6
  • 42
    • 45249119952 scopus 로고    scopus 로고
    • Glioma stem cells: a midterm exam
    • Stiles C.D., Rowitch D.H. Glioma stem cells: a midterm exam. Neuron 2008, 58:832-846.
    • (2008) Neuron , vol.58 , pp. 832-846
    • Stiles, C.D.1    Rowitch, D.H.2
  • 43
    • 0026535505 scopus 로고
    • Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system
    • Reynolds B.A., Weiss S. Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. Science 1992, 255:1707-1710.
    • (1992) Science , vol.255 , pp. 1707-1710
    • Reynolds, B.A.1    Weiss, S.2
  • 44
    • 33750541962 scopus 로고    scopus 로고
    • Glioblastoma-derived tumorospheres identify a population of tumor stem-like cells with angiogenic potential and enhanced multidrug resistance phenotype
    • Salmaggi A., Boiardi A., Gelati M., Russo A., Calatozzolo C., Ciusani E., et al. Glioblastoma-derived tumorospheres identify a population of tumor stem-like cells with angiogenic potential and enhanced multidrug resistance phenotype. Glia 2006, 54:850-860.
    • (2006) Glia , vol.54 , pp. 850-860
    • Salmaggi, A.1    Boiardi, A.2    Gelati, M.3    Russo, A.4    Calatozzolo, C.5    Ciusani, E.6
  • 45
    • 34447625239 scopus 로고    scopus 로고
    • Neural stem cell markers, nestin and musashi proteins, in the progression of human glioma: correlation of nestin with prognosis of patient survival
    • Strojnik T., Rosland G.V., Sakariassen P.O., Kavalar R., Lah T. Neural stem cell markers, nestin and musashi proteins, in the progression of human glioma: correlation of nestin with prognosis of patient survival. Surg Neurol 2007, 68:133-144.
    • (2007) Surg Neurol , vol.68 , pp. 133-144
    • Strojnik, T.1    Rosland, G.V.2    Sakariassen, P.O.3    Kavalar, R.4    Lah, T.5
  • 46
    • 79951893576 scopus 로고    scopus 로고
    • Association of stem cell-related markers and survival in astrocytic gliomas
    • Wan F., Herold-Mende C., Campos B., Centner F.-S., Dictus C., Becker N., et al. Association of stem cell-related markers and survival in astrocytic gliomas. Biomarkers 2011, 16:136-143.
    • (2011) Biomarkers , vol.16 , pp. 136-143
    • Wan, F.1    Herold-Mende, C.2    Campos, B.3    Centner, F.-S.4    Dictus, C.5    Becker, N.6
  • 47
    • 0036537894 scopus 로고    scopus 로고
    • Musashi: a translational regulator of cell fate
    • Okano H., Imai T., Okabe M. Musashi: a translational regulator of cell fate. JCell Sci 2002, 115:1355-1359.
    • (2002) JCell Sci , vol.115 , pp. 1355-1359
    • Okano, H.1    Imai, T.2    Okabe, M.3
  • 48
    • 0035045418 scopus 로고    scopus 로고
    • Expression of the neural RNA-binding protein musashi1 in human gliomas
    • Toda M., Iizuka Y., Yu W., Imai T., Ikeda E., Yoshida K., et al. Expression of the neural RNA-binding protein musashi1 in human gliomas. Glia 2001, 34:1-7.
    • (2001) Glia , vol.34 , pp. 1-7
    • Toda, M.1    Iizuka, Y.2    Yu, W.3    Imai, T.4    Ikeda, E.5    Yoshida, K.6
  • 50
    • 33845785589 scopus 로고    scopus 로고
    • Differentiation profile of brain tumor stem cells: a comparative study with neural stem cells
    • Zhang Q.B., Ji X.Y., Huang Q., Dong J., De Zhu Y., Lan Q. Differentiation profile of brain tumor stem cells: a comparative study with neural stem cells. Cell Res 2006, 16:909-915.
    • (2006) Cell Res , vol.16 , pp. 909-915
    • Zhang, Q.B.1    Ji, X.Y.2    Huang, Q.3    Dong, J.4    De Zhu, Y.5    Lan, Q.6
  • 52
    • 79251591038 scopus 로고    scopus 로고
    • Glioblastoma, cancer stem cells and hypoxia
    • Bar E.E. Glioblastoma, cancer stem cells and hypoxia. Brain Pathol 2011, 21:119-129.
    • (2011) Brain Pathol , vol.21 , pp. 119-129
    • Bar, E.E.1
  • 53
    • 0034213146 scopus 로고    scopus 로고
    • Expression of hypoxia-inducible factor 1 alpha in brain tumors - association with angiogenesis, invasion, and progression
    • Zagzag D., Zhong H., Scalzitti J.M., Laughner E., Simons J.W., Semenza G.L. Expression of hypoxia-inducible factor 1 alpha in brain tumors - association with angiogenesis, invasion, and progression. Cancer 2000, 88:2606-2618.
    • (2000) Cancer , vol.88 , pp. 2606-2618
    • Zagzag, D.1    Zhong, H.2    Scalzitti, J.M.3    Laughner, E.4    Simons, J.W.5    Semenza, G.L.6
  • 54
    • 65749106405 scopus 로고    scopus 로고
    • Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells
    • Li Z., Bao S., Wu Q., Wang H., Eyler C., Sathornsumetee S., et al. Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells. Cancer Cell 2009, 15:501-513.
    • (2009) Cancer Cell , vol.15 , pp. 501-513
    • Li, Z.1    Bao, S.2    Wu, Q.3    Wang, H.4    Eyler, C.5    Sathornsumetee, S.6
  • 55
    • 70449687092 scopus 로고    scopus 로고
    • Hypoxia promotes expansion of the CD133-positive glioma stem cells through activation of HIF-1 alpha
    • Soeda A., Park M., Lee D., Mintz A., Androutsellis-Theotokis A., McKay R.D., et al. Hypoxia promotes expansion of the CD133-positive glioma stem cells through activation of HIF-1 alpha. Oncogene 2009, 28:3949-3959.
    • (2009) Oncogene , vol.28 , pp. 3949-3959
    • Soeda, A.1    Park, M.2    Lee, D.3    Mintz, A.4    Androutsellis-Theotokis, A.5    McKay, R.D.6
  • 56
    • 80054716821 scopus 로고    scopus 로고
    • The role of the 3D environment in hypoxia-induced drug and apoptosis resistance
    • Kim J.W., Ho W.J., Wu B.M. The role of the 3D environment in hypoxia-induced drug and apoptosis resistance. Anticancer Res 2011, 31:3237-3245.
    • (2011) Anticancer Res , vol.31 , pp. 3237-3245
    • Kim, J.W.1    Ho, W.J.2    Wu, B.M.3
  • 57
    • 77956503727 scopus 로고    scopus 로고
    • Hypoxia increases the expression of stem-cell markers and promotes clonogenicity in glioblastoma neurospheres
    • Bar E.E., Lin A., Mahairaki V., Matsui W., Eberhart C.G. Hypoxia increases the expression of stem-cell markers and promotes clonogenicity in glioblastoma neurospheres. Am J Pathol 2010, 177:1491-1502.
    • (2010) Am J Pathol , vol.177 , pp. 1491-1502
    • Bar, E.E.1    Lin, A.2    Mahairaki, V.3    Matsui, W.4    Eberhart, C.G.5
  • 58
    • 18744377966 scopus 로고    scopus 로고
    • Adenovirus-mediated expression of antisense MMP-9 in glioma cells inhibits tumor growth and invasion
    • Lakka S.S., Rajan M., Gondi C., Yanamandra N., Chandrasekar N., Jasti S.L., et al. Adenovirus-mediated expression of antisense MMP-9 in glioma cells inhibits tumor growth and invasion. Oncogene 2002, 21:8011-8019.
    • (2002) Oncogene , vol.21 , pp. 8011-8019
    • Lakka, S.S.1    Rajan, M.2    Gondi, C.3    Yanamandra, N.4    Chandrasekar, N.5    Jasti, S.L.6
  • 59
  • 62
    • 77952330272 scopus 로고    scopus 로고
    • Intratumoral hypoxic gradient drives stem cells distribution and MGMT expression in glioblastoma
    • Pistollato F., Abbadi S., Rampazzo E., Persano L., Della Puppa A., Frasson C., et al. Intratumoral hypoxic gradient drives stem cells distribution and MGMT expression in glioblastoma. Stem Cells 2010, 28:851-862.
    • (2010) Stem Cells , vol.28 , pp. 851-862
    • Pistollato, F.1    Abbadi, S.2    Rampazzo, E.3    Persano, L.4    Della Puppa, A.5    Frasson, C.6
  • 63
    • 70349296853 scopus 로고    scopus 로고
    • The ABCG2 resistance network of glioblastoma
    • Bleau A.-M., Huse J.T., Holland E.C. The ABCG2 resistance network of glioblastoma. Cell Cycle 2009, 8:2937-2945.
    • (2009) Cell Cycle , vol.8 , pp. 2937-2945
    • Bleau, A.-M.1    Huse, J.T.2    Holland, E.C.3
  • 64
    • 84878535135 scopus 로고    scopus 로고
    • Melatonin-induced methylation of the ABCG2/BCRP promoter as a novel mechanism to overcome multidrug resistance in brain tumour stem cells
    • Martin V., Sanchez-Sanchez A.M., Herrera F., Gomez-Manzano C., Fueyo J., Alvarez-Vega M.A., et al. Melatonin-induced methylation of the ABCG2/BCRP promoter as a novel mechanism to overcome multidrug resistance in brain tumour stem cells. Br J Cancer 2013, 108:2005-2012.
    • (2013) Br J Cancer , vol.108 , pp. 2005-2012
    • Martin, V.1    Sanchez-Sanchez, A.M.2    Herrera, F.3    Gomez-Manzano, C.4    Fueyo, J.5    Alvarez-Vega, M.A.6
  • 65
    • 58149166478 scopus 로고    scopus 로고
    • Characterization of a side population of astrocytoma cells in response to temozolomide
    • Chua C., Zaiden N., Chong K.-H., See S.-J., Wong M.-C., Ang B.-T., et al. Characterization of a side population of astrocytoma cells in response to temozolomide. JNeurosurg 2008, 109:856-866.
    • (2008) JNeurosurg , vol.109 , pp. 856-866
    • Chua, C.1    Zaiden, N.2    Chong, K.-H.3    See, S.-J.4    Wong, M.-C.5    Ang, B.-T.6
  • 66
    • 16844368698 scopus 로고    scopus 로고
    • Tumour stem cells and drug resistance
    • Dean M., Fojo T., Bates S. Tumour stem cells and drug resistance. Nat Rev Cancer 2005, 5:275-284.
    • (2005) Nat Rev Cancer , vol.5 , pp. 275-284
    • Dean, M.1    Fojo, T.2    Bates, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.