Melatonin-induced methylation of the ABCG2/BCRP promoter as a novel mechanism to overcome multidrug resistance in brain tumour stem cells

British Journal of Cancer

Volumn 108, Issue 10, 2013, Pages 2005-2012

  Martin V ^a,b   Sanchez Sanchez, A M ^a,b   Herrera, F ^c   Gomez Manzano, C ^d   Fueyo, J ^d   Alvarez Vega, M A ^e   Antolin I ^a   Rodriguez, C ^a,b  

^a Faculty de Medicina   (Spain)

^b DEPARTAMENTO DE BIOQUÍMICA Y BIOLOGÍA MOLECULAR   (Spain)

^c INSTITUTO DE MEDICINA MOLECULAR   (Portugal)

^d UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^e HOSPITAL UNIVERSITARIO CENTRAL DE ASTURIAS   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

BREAST CANCER RESISTANCE PROTEIN; DNA METHYLTRANSFERASE INHIBITOR; DOXORUBICIN; MELATONIN; MESSENGER RNA; MITOXANTRONE; TEMOZOLOMIDE;

ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CANCER RESISTANCE; CANCER STEM CELL; CELL VIABILITY; CONTROLLED STUDY; FLOW CYTOMETRY; GLIOBLASTOMA; HUMAN; HUMAN CELL; MULTIDRUG RESISTANCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN METHYLATION; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS; ATP-BINDING CASSETTE TRANSPORTERS; BRAIN; BRAIN NEOPLASMS; CELL LINE, TUMOR; DNA METHYLATION; DRUG EVALUATION, PRECLINICAL; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; DRUG SYNERGISM; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIOBLASTOMA; HUMANS; MELATONIN; NEOPLASM PROTEINS; NEOPLASTIC STEM CELLS; PROMOTER REGIONS, GENETIC;

EID: 84878535135     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/bjc.2013.188     Document Type: Article

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