Matrix metalloproteinase-2 activation modulates glioma cell migration

Journal of Cell Science

Volumn 110, Issue 19, 1997, Pages 2473-2482

  Deryugina, Elena I ^a   Bourdon, Mario A ^a   Luo, Guang Xiang ^b   Reisfeld, Ralph A ^b   Strongin, Alex ^a  

^a La Jolla Institute for Experimental Medicine   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Cell adhesion; Cell migration; Extracellular matrix; Integrin; Matrix metalloproteinase; MMP 2; MT MMP 1; TIMP 2

Indexed keywords

EID: 0001125655     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Ailenberg, M. and Silverman, M. (1996). Cellular activation of mesangial gelatinase A by cytochalasin D is accompanied by enhanced mRNA expression of both gelatinase A and its membrane-associated gelatinase A activator (MT-MMP). Biochem. J. 313, 879-884.
2. Aimes, R. T. and Quigley, J. P. (1995). Matrix metalloproteinase-2 is an interstitial collagenase. Inhibitor-free enzyme catalyzes the cleavage of collagen fibrils and soluble native type I collagen generating the specific 3/4- and 1/4-length fragments. J. Biol. Chem. 270, 5872-5876.
3. Ashkenas, J., Damsky, C. H., Bissel, M. J. and Werb, Z. (1994). Integrins, signaling, and remodeling of the extracellular matrix. In Integrins. Molecular and Biological Responce to the Extracellular Matrix (ed. D. A. Cheresh and R. P. Mecham), pp. 79-109. Academic Press, San Diego.
4. Aznavoorian, S., Murphy, A. N., Stetler-Stevenson, W. G. and Liotta, L. A. (1993). Molecular aspects of tumor cell invasion and metastasis. Cancer 71, 1368-1383.
5. Behrendtsen, O. and Werb, Z. (1997). Metalloproteinases regulate parietal endoderm differentiating and migrating in culruted mouse embryos. Dev Dynam. 208, 255-265.
6. Birkedal-Hansen, H., Moore, W. G. I., Bodden, M. K., Windsor, L. J., Birkedal-Hansen, B., DeCarlo, A. and Engler, J. A. (1993). Matrix metalloproteinases: a review. Crit. Rev. Oral Biol. Med. 4, 197-250.
7. Brooks, P. C., Stromblad, S., Sanders, L. C., von Schalscha, T. L., Aimes, R. T., Stetler-Stevenson, W. G., Quigley, J. P. and Cheresh, D. A. (1996). Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin αvβ3. Cell 85, 683-693.
8. Chintala, S. K., Sawaya, R., Gokaslan, Z. L. and Rao, J. S. (1996). Modulation of matrix metalloproteinase-2 and invasion in human glioma cells by alpha 3 beta 1 integrin. Cancer Lett. 103, 201-208.
9. Corcoran, M. L. and Stetler-Stevenson, W. G. (1995). Tissue inhibitor of metalloproteinase-2 stimulates fibroblast proliferation via a cAMP-dependent mechanism. J. Biol. Chem. 270, 13453-13459.
10. Coussens, L. M. and Werb, Z. (1996). Matrix metalloproteinases and the development of cancer. Chem. Biol. 3, 895-904.
11. Deryugina, E. I. and Bourdon, M. A. (1996). Tenascin mediates human glioma cell migration and modulates cell migration on fibronectin. J. Cell Sci. 109, 643-652.
12. Deryugina, E. I., Strongin, A., Yu, C. and Bourdon, M. A. (1996). A novel monoclonal antibody, L1A3, is directed to the functional site of the αv integrin subunit. Hybridoma 15, 279-288.
13. Deryugina, E. I., Luo, G.-X., Reisfeld, R. A., Bourdon, M. A. and Strongin, A. (1997). Tumor cell invasion through matrigel is regulated by activated matrix metalloproteinase-2. Anticancer Res. 17 (in press).
14. DiMilla, P. A., Stone, J. A., Quinn, J. A., Albelda, S. M. and Lauffenburger, D. A. (1993). Maximum migration of human smooth muscle cells on fibronectin and type IV collagen occurs at intermediate attachment strength. J. Cell Biol. 122, 729-737.
15. 1 integrins. Cancer Res. 56, 1939-1947.
16. Goldberg, G. I., Marmer, B. L., Grant, G. A., Eisen, A. Z., Wilheim, S. and He, C. (1989). Human 72-kilodalton type IV collagenase forms a complex with tissue inhibitor of metalloproteinases designated TIMP-2. Proc. Nat. Acad. Sci. USA 86, 8207-8211.
17. Greene, J., Wang, M., Liu, Y. I., Raymond, L. A., Rosen, C. and Shi, Y. I. (1996). Molecular cloning and characterization of human tissue inhibitor of metalloproteinase 4. J. Biol. Chem. 271, 30375-30380.
18. Howard, E., Bullen, E. C. and Banda, M. J. (1991). Preferential inhibition of 72kDa and 92 kDa gelatinases by TIMP-2. J. Biol. Chem. 266, 13070-13075.
19. Huhtala, P., Humphries, M. J., McCarthy, J. B., Tremble, P. M., Werb, Z. and Damsky, C. H. (1995). Cooperative signaling by α5β1 and α4β1 integrins regulates metalloproteinase gene expression in fibroblasts adhering to fibronectin. J. Cell Biol. 129, 867-879.
20. Imai, K., Ohuchi, E., Aoki, T., Nomura, H., Fujii, Y., Sato, H., Seiki, M., and Okada, Y. (1996). Membrane-type matrix metalloproteinase 1 is a gelatinolytic enzyme and is secreted in a complex with tissue inhibitor of metalloproteinases 2. Cancer Res. 56, 2707-2710.
21. Montgomery, A. M., Mueller, B. M., Reisfeld, R. A., Taylor, S. M. and DeClerck, Y. A. (1994). Effect of tissue inhibitor of the matrix metalloproteinase-2 expression on growth and spontaneous metastasis of a human melanoma cell line. Cancer Res. 54, 5467-5473.