-
1
-
-
0034681260
-
Regulated intramembrane proteolysis: A control mechanism conserved from bacteria to humans
-
M.S. Brown, J. Ye, R.B. Rawson, and J.L. Goldstein Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans Cell 100 4 2000 391 398
-
(2000)
Cell
, vol.100
, Issue.4
, pp. 391-398
-
-
Brown, M.S.1
Ye, J.2
Rawson, R.B.3
Goldstein, J.L.4
-
2
-
-
0033621152
-
Are presenilins intramembrane-cleaving proteases? Implications for the molecular mechanism of Alzheimer's disease
-
DOI 10.1021/bi991080q
-
M.S. Wolfe, J. De Los Angeles, D.D. Miller, W. Xia, and D.J. Selkoe Are presenilins intramembrane-cleaving proteases? Implications for the molecular mechanism of Alzheimer's disease Biochemistry 38 35 1999 11223 11230 (Pubitemid 29420941)
-
(1999)
Biochemistry
, vol.38
, Issue.35
, pp. 11223-11230
-
-
Wolfe, M.S.1
De Los Angeles, J.2
Miller, D.D.3
Xia, W.4
Selkoe, D.J.5
-
3
-
-
0031301274
-
Complementation cloning of S2P, a gene encoding a putative metalloprotease required for intramembrane cleavage of SREBPs
-
R.B. Rawson, N.G. Zelenski, D. Nijhawan, J. Ye, J. Sakai, M.T. Hasan, T.Y. Chang, M.S. Brown, and J.L. Goldstein Complementation cloning of S2P, a gene encoding a putative metalloprotease required for intramembrane cleavage of SREBPs Mol. Cell 1 1 1997 47 57 (Pubitemid 127376392)
-
(1997)
Molecular Cell
, vol.1
, Issue.1
, pp. 47-57
-
-
Rawson, R.B.1
Zelenski, N.G.2
Nijhawan, D.3
Ye, J.4
Sakai, J.5
Hasan, M.T.6
Chang, T.Y.7
Brown, M.S.8
Goldstein, J.L.9
-
4
-
-
39849102805
-
Regulation of sterol synthesis in eukaryotes
-
P.J. Espenshade, and A.L. Hughes Regulation of sterol synthesis in eukaryotes Annu. Rev. Genet. 41 2007 401 427
-
(2007)
Annu. Rev. Genet.
, vol.41
, pp. 401-427
-
-
Espenshade, P.J.1
Hughes, A.L.2
-
5
-
-
70350411534
-
The site-2 protease at Ten
-
N.M. Hooper, U. Lendeckel, Springer Dordrecht
-
R.B. Rawson, and W.P. Li The site-2 protease at Ten N.M. Hooper, U. Lendeckel, Intramembrane-Cleaving Proteases (I-CLiPs) 2007 Springer Dordrecht 1 16
-
(2007)
Intramembrane-Cleaving Proteases (I-CLiPs)
, pp. 1-16
-
-
Rawson, R.B.1
Li, W.P.2
-
6
-
-
0028087833
-
Somatic cell genetic and biochemical characterization of cell lines resulting from human genomic DNA transfections of Chinese hamster ovary cell mutants defective in sterol-dependent activation of sterol synthesis and LDL receptor expression
-
DOI 10.1007/BF02254759
-
M.T. Hasan, C.C. Chang, and T.Y. Chang Somatic cell genetic and biochemical characterization of cell lines resulting from human genomic DNA transfections of Chinese hamster ovary cell mutants defective in sterol-dependent activation of sterol synthesis and LDL receptor expression Somat. Cell Mol. Genet. 20 3 1994 183 194 (Pubitemid 24308069)
-
(1994)
Somatic Cell and Molecular Genetics
, vol.20
, Issue.3
, pp. 183-194
-
-
Hasan, M.T.1
Chang, C.C.Y.2
Chang, T.Y.3
-
7
-
-
0029036451
-
Evolutionary families of metallopeptidases
-
N.D. Rawlings, and A.J. Barrett Evolutionary families of metallopeptidases Methods Enzymol. 248 1995 183 228
-
(1995)
Methods Enzymol.
, vol.248
, pp. 183-228
-
-
Rawlings, N.D.1
Barrett, A.J.2
-
8
-
-
0033618342
-
Membrane topology of S2P, a protein required for intramembranous cleavage of sterol regulatory element-binding proteins
-
N.G. Zelenski, R.B. Rawson, M.S. Brown, and J.L. Goldstein Membrane topology of S2P, a protein required for intramembranous cleavage of sterol regulatory element-binding proteins J. Biol. Chem. 274 31 1999 21973 21980
-
(1999)
J. Biol. Chem.
, vol.274
, Issue.31
, pp. 21973-21980
-
-
Zelenski, N.G.1
Rawson, R.B.2
Brown, M.S.3
Goldstein, J.L.4
-
10
-
-
36849037428
-
Structure of a site-2 protease family intramembrane metalloprotease
-
DOI 10.1126/science.1150755
-
L. Feng, H. Yan, Z. Wu, N. Yan, Z. Wang, P.D. Jeffrey, and Y. Shi Structure of a site-2 protease family intramembrane metalloprotease Science 318 5856 2007 1608 1612 (Pubitemid 350233656)
-
(2007)
Science
, vol.318
, Issue.5856
, pp. 1608-1612
-
-
Feng, L.1
Yan, H.2
Wu, Z.3
Yan, N.4
Wang, Z.5
Jeffrey, P.D.6
Shi, Y.7
-
11
-
-
70349488828
-
Intramembrane proteolytic cleavage of a membrane-tethered transcription factor by a metalloprotease depends on ATP
-
R. Zhou, C. Cusumano, D. Sui, R.M. Garavito, and L. Kroos Intramembrane proteolytic cleavage of a membrane-tethered transcription factor by a metalloprotease depends on ATP Proc. Natl. Acad. Sci. U. S. A. 106 38 2009 16174 16179
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, Issue.38
, pp. 16174-16179
-
-
Zhou, R.1
Cusumano, C.2
Sui, D.3
Garavito, R.M.4
Kroos, L.5
-
12
-
-
29344444795
-
Site-2 protease regulated intramembrane proteolysis: Sequence homologs suggest an ancient signaling cascade
-
DOI 10.1110/ps.051766506
-
L.N. Kinch, K. Ginalski, and N.V. Grishin Site-2 protease regulated intramembrane proteolysis: sequence homologs suggest an ancient signaling cascade Protein Sci. 15 1 2006 84 93 (Pubitemid 43004236)
-
(2006)
Protein Science
, vol.15
, Issue.1
, pp. 84-93
-
-
Kinch, L.N.1
Ginalski, K.2
Grishin, N.V.3
-
13
-
-
0033529560
-
Autocatalytic processing of site-1 protease removes propeptide and permits cleavage of sterol regulatory element-binding proteins
-
P.J. Espenshade, D. Cheng, J.L. Goldstein, and M.S. Brown Autocatalytic processing of site-1 protease removes propeptide and permits cleavage of sterol regulatory element-binding proteins J. Biol. Chem. 274 32 1999 22795 22804
-
(1999)
J. Biol. Chem.
, vol.274
, Issue.32
, pp. 22795-22804
-
-
Espenshade, P.J.1
Cheng, D.2
Goldstein, J.L.3
Brown, M.S.4
-
14
-
-
0033599028
-
Transport-dependent proteolysis of SREBP: Relocation of Site-1 protease from Golgi to ER obviates the need for SREBP transport to Golgi
-
R.A. DeBose-Boyd, M.S. Brown, W.P. Li, A. Nohturfft, J.L. Goldstein, and P.J. Espenshade Transport-dependent proteolysis of SREBP: relocation of site-1 protease from Golgi to ER obviates the need for SREBP transport to Golgi Cell 99 7 1999 703 712 (Pubitemid 30017641)
-
(1999)
Cell
, vol.99
, Issue.7
, pp. 703-712
-
-
DeBose-Boyd, R.A.1
Brown, M.S.2
Li, W.-P.3
Nohturfft, A.4
Goldstein, J.L.5
Espenshade, P.J.6
-
15
-
-
5644244829
-
Dependence of site-2 protease cleavage of ATF6 on prior site-1 protease digestion is determined by the size of the luminal domain of ATF6
-
DOI 10.1074/jbc.M408466200
-
J. Shen, and R. Prywes Dependence of site-2 protease cleavage of ATF6 on prior site-1 protease digestion is determined by the size of the luminal domain of ATF6 J. Biol. Chem. 279 41 2004 43046 43051 (Pubitemid 39372199)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.41
, pp. 43046-43051
-
-
Shen, J.1
Prywes, R.2
-
16
-
-
0036480346
-
The SREBP pathway in Drosophila: Regulation by palmitate, not sterols
-
DOI 10.1016/S1534-5807(01)00119-8, PII S1534580701001198
-
A.C. Seegmiller, I. Dobrosotskaya, J.L. Goldstein, Y.K. Ho, M.S. Brown, and R.B. Rawson The SREBP pathway in Drosophila: regulation by palmitate, not sterols Dev. Cell 2 2 2002 229 238 (Pubitemid 38351587)
-
(2002)
Developmental Cell
, vol.2
, Issue.2
, pp. 229-238
-
-
Seegmiller, A.C.1
Dobrosotskaya, I.2
Goldstein, J.L.3
Ho, Y.K.4
Brown, M.S.5
Rawson, R.B.6
-
17
-
-
58049199407
-
A pair of circularly permutated PDZ domains control RseP, the S2P family intramembrane protease of Escherichia coli
-
K. Inaba, M. Suzuki, K. Maegawa, S. Akiyama, K. Ito, and Y. Akiyama A pair of circularly permutated PDZ domains control RseP, the S2P family intramembrane protease of Escherichia coli J. Biol. Chem. 283 50 2008 35042 35052
-
(2008)
J. Biol. Chem.
, vol.283
, Issue.50
, pp. 35042-35052
-
-
Inaba, K.1
Suzuki, M.2
Maegawa, K.3
Akiyama, S.4
Ito, K.5
Akiyama, Y.6
-
18
-
-
0034625081
-
Asparagine-proline sequence within membrane-spanning segment of SREBP triggers intramembrane Site-2 protease
-
DOI 10.1073/pnas.97.10.5123
-
J. Ye, U.P. Dave, N.V. Grishin, J.L. Goldstein, and M.S. Brown Asparagine-proline sequence within membrane-spanning segment of SREBP triggers intramembrane cleavage by site-2 protease Proc. Natl. Acad. Sci. U. S. A. 97 10 2000 5123 5128 (Pubitemid 30313682)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.10
, pp. 5123-5128
-
-
Ye, J.1
Dave, U.P.2
Grishin, N.V.3
Goldstein, J.L.4
Brown, M.S.5
-
19
-
-
0036809216
-
Requirements for signal peptide peptidase-catalyzed intramembrane proteolysis
-
DOI 10.1016/S1097-2765(02)00655-X
-
M.K. Lemberg, and B. Martoglio Requirements for signal peptide peptidase-catalyzed intramembrane proteolysis Mol. Cell 10 4 2002 735 744 (Pubitemid 35335630)
-
(2002)
Molecular Cell
, vol.10
, Issue.4
, pp. 735-744
-
-
Lemberg, M.K.1
Martoglio, B.2
-
20
-
-
0038771224
-
Substrate specificity of Rhomboid intramembrane proteases is governed by helix-breaking residues in the substrate transmembrane domain
-
DOI 10.1016/S1097-2765(03)00181-3
-
S. Urban, and M. Freeman Substrate specificity of rhomboid intramembrane proteases is governed by helix-breaking residues in the substrate transmembrane domain Mol. Cell 11 6 2003 1425 1434 (Pubitemid 36776530)
-
(2003)
Molecular Cell
, vol.11
, Issue.6
, pp. 1425-1434
-
-
Urban, S.1
Freeman, M.2
-
21
-
-
0032726294
-
Common protein architecture and binding sites in proteases utilizing a Ser/Lys dyad mechanism
-
M. Paetzel, and N.C. Strynadka Common protein architecture and binding sites in proteases utilizing a Ser/Lys dyad mechanism Protein Sci. 8 11 1999 2533 2536 (Pubitemid 29536424)
-
(1999)
Protein Science
, vol.8
, Issue.11
, pp. 2533-2536
-
-
Paetzel, M.1
Strynadka, N.C.J.2
-
22
-
-
33750886311
-
Crystal structure of a rhomboid family intramembrane protease
-
Y. Wang, Y. Zhang, and Y. Ha Crystal structure of a rhomboid family intramembrane protease Nature 444 7116 2006 179 180
-
(2006)
Nature
, vol.444
, Issue.7116
, pp. 179-180
-
-
Wang, Y.1
Zhang, Y.2
Ha, Y.3
-
23
-
-
33846543356
-
The crystal structure of the rhomboid peptidase from Haemophilus influenzae provides insight into intramembrane porteolysis
-
DOI 10.1073/pnas.0609981104
-
M.J. Lemieux, S.J. Fischer, M.M. Cherney, K.S. Bateman, and M.N. James The crystal structure of the rhomboid peptidase from Haemophilus influenzae provides insight into intramembrane proteolysis Proc. Natl. Acad. Sci. U. S. A. 104 3 2007 750 754 (Pubitemid 46154682)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.3
, pp. 750-754
-
-
Lemieux, M.J.1
Fischer, S.J.2
Cherney, M.M.3
Bateman, K.S.4
James, M.N.G.5
-
24
-
-
63649088506
-
Structure and mechanism of intramembrane protease
-
Y. Ha Structure and mechanism of intramembrane protease Semin. Cell Dev. Biol. 20 2 2009 240 250
-
(2009)
Semin. Cell Dev. Biol.
, vol.20
, Issue.2
, pp. 240-250
-
-
Ha, Y.1
-
25
-
-
31544450017
-
A chloroplastic inner envelope membrane protease is essential for plant development
-
DOI 10.1016/j.febslet.2005.12.098, PII S0014579306000123
-
B. Bolter, A. Nada, H. Fulgosi, and J. Soll A chloroplastic inner envelope membrane protease is essential for plant development FEBS Lett. 580 3 2006 789 794 (Pubitemid 43153786)
-
(2006)
FEBS Letters
, vol.580
, Issue.3
, pp. 789-794
-
-
Bolter, B.1
Nada, A.2
Fulgosi, H.3
Soll, J.4
-
26
-
-
53149117026
-
Membrane-bound transcription factors in plants
-
P.J. Seo, S.G. Kim, and C.M. Park Membrane-bound transcription factors in plants Trends Plant Sci. 13 10 2008 550 556
-
(2008)
Trends Plant Sci.
, vol.13
, Issue.10
, pp. 550-556
-
-
Seo, P.J.1
Kim, S.G.2
Park, C.M.3
-
27
-
-
70350397502
-
Cryptococcus neoformans Site-2 protease is required for virulence and survival in the presence of azole drugs
-
C.M. Bien, Y.C. Chang, W.D. Nes, K.J. Kwon-Chung, and P.J. Espenshade Cryptococcus neoformans Site-2 protease is required for virulence and survival in the presence of azole drugs Mol. Microbiol. 74 3 2009 672 690
-
(2009)
Mol. Microbiol.
, vol.74
, Issue.3
, pp. 672-690
-
-
Bien, C.M.1
Chang, Y.C.2
Nes, W.D.3
Kwon-Chung, K.J.4
Espenshade, P.J.5
-
28
-
-
0034515724
-
ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs
-
DOI 10.1016/S1097-2765(00)00133-7
-
J. Ye, R.B. Rawson, R. Komuro, X. Chen, U.P. Dave, R. Prywes, M.S. Brown, and J.L. Goldstein ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs Mol. Cell 6 6 2000 1355 1364 (Pubitemid 32045928)
-
(2000)
Molecular Cell
, vol.6
, Issue.6
, pp. 1355-1364
-
-
Ye, J.1
Rawson, R.B.2
Komuro, R.3
Chen, X.4
Dave, U.P.5
Prywes, R.6
Brown, M.S.7
Goldstein, J.L.8
-
29
-
-
32044453080
-
Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response
-
DOI 10.1016/j.cell.2005.11.040, PII S0092867406000043
-
K. Zhang, X. Shen, J. Wu, K. Sakaki, T. Saunders, D.T. Rutkowski, S.H. Back, and R.J. Kaufman Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response Cell 124 3 2006 587 599 (Pubitemid 43199443)
-
(2006)
Cell
, vol.124
, Issue.3
, pp. 587-599
-
-
Zhang, K.1
Shen, X.2
Wu, J.3
Sakaki, K.4
Saunders, T.5
Rutkowski, D.T.6
Back, S.H.7
Kaufman, R.J.8
-
30
-
-
0142027805
-
Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes
-
DOI 10.1073/pnas.1534923100
-
J.D. Horton, N.A. Shah, J.A. Warrington, N.N. Anderson, S.W. Park, M.S. Brown, and J.L. Goldstein Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes Proc. Natl. Acad. Sci. U. S. A. 100 21 2003 12027 12032 (Pubitemid 37271509)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.21
, pp. 12027-12032
-
-
Horton, J.D.1
Shah, N.A.2
Warrington, J.A.3
Anderson, N.N.4
Park, S.W.5
Brown, M.S.6
Goldstein, J.L.7
-
31
-
-
56449110891
-
Switch-like control of SREBP-2 transport triggered by small changes in ER cholesterol: A delicate balance
-
A. Radhakrishnan, J.L. Goldstein, J.G. McDonald, and M.S. Brown Switch-like control of SREBP-2 transport triggered by small changes in ER cholesterol: a delicate balance Cell Metab. 8 6 2008 512 521
-
(2008)
Cell Metab.
, vol.8
, Issue.6
, pp. 512-521
-
-
Radhakrishnan, A.1
Goldstein, J.L.2
McDonald, J.G.3
Brown, M.S.4
-
32
-
-
0032185770
-
Molecular identification of the sterol-regulated luminal protease that cleaves SREBPs and controls lipid composition of animal cells
-
J. Sakai, R.B. Rawson, P.J. Espenshade, D. Cheng, A.C. Seegmiller, J.L. Goldstein, and M.S. Brown Molecular identification of the sterol-regulated luminal protease that cleaves SREBPs and controls lipid composition of animal cells Mol. Cell 2 4 1998 505 514 (Pubitemid 128381303)
-
(1998)
Molecular Cell
, vol.2
, Issue.4
, pp. 505-514
-
-
Sakai, J.1
Rawson, R.B.2
Espenshade, P.J.3
Cheng, D.4
Seegmiller, A.C.5
Goldstein, J.L.6
Brown, M.S.7
-
33
-
-
13044279492
-
Mammalian subtilisin/kexin isozyme SKI-1: A widely expressed proprotein convertase with a unique cleavage specificity and cellular localization
-
DOI 10.1073/pnas.96.4.1321
-
N.G. Seidah, S.J. Mowla, J. Hamelin, A.M. Mamarbachi, S. Benjannet, B.B. Toure, A. Basak, J.S. Munzer, J. Marcinkiewicz, M. Zhong, J.C. Barale, C. Lazure, R.A. Murphy, M. Chretien, and M. Marcinkiewicz Mammalian subtilisin/kexin isozyme SKI-1: a widely expressed proprotein convertase with a unique cleavage specificity and cellular localization Proc. Natl. Acad. Sci. U. S. A. 96 4 1999 1321 1326 (Pubitemid 29098449)
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, Issue.4
, pp. 1321-1326
-
-
Seidah, N.G.1
Mowla, S.J.2
Hamelin, J.3
Mamarbachi, A.M.4
Benjannet, S.5
Toure, B.B.6
Basak, A.7
Munzer, J.S.8
Marcinkiewicz, J.9
Zhong, M.10
Barale, J.-C.11
Lazure, C.12
Murphy, R.A.13
Chretien, M.14
Marcinkiewicz, M.15
-
34
-
-
0030604717
-
Sterol-regulated release of SREBP-2 from cell membranes requires two sequential cleavages, one within a transmembrane segment
-
DOI 10.1016/S0092-8674(00)81304-5
-
J. Sakai, E.A. Duncan, R.B. Rawson, X. Hua, M.S. Brown, and J.L. Goldstein Sterol-regulated release of SREBP-2 from cell membranes requires two sequential cleavages, one within a transmembrane segment Cell 85 7 1996 1037 1046 (Pubitemid 26231170)
-
(1996)
Cell
, vol.85
, Issue.7
, pp. 1037-1046
-
-
Sakai, J.1
Duncan, E.A.2
Rawson, R.B.3
Hua, X.4
Brown, M.S.5
Goldstein, J.L.6
-
35
-
-
0030911517
-
Cleavage site for sterol-regulated protease localized to a Leu-Ser bond in the lumenal loop of sterol regulatory element-binding protein-2
-
DOI 10.1074/jbc.272.19.12778
-
E.A. Duncan, M.S. Brown, J.L. Goldstein, and J. Sakai Cleavage site for sterol-regulated protease localized to a leu-Ser bond in the lumenal loop of sterol regulatory element-binding protein-2 J. Biol. Chem. 272 19 1997 12778 12785 (Pubitemid 27203378)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.19
, pp. 12778-12785
-
-
Duncan, E.A.1
Brown, M.S.2
Goldstein, J.L.3
Sakai, J.4
-
36
-
-
0028225462
-
SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis
-
X. Wang, R. Sato, M.S. Brown, X. Hua, and J.L. Goldstein SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis Cell 77 1 1994 53 62
-
(1994)
Cell
, vol.77
, Issue.1
, pp. 53-62
-
-
Wang, X.1
Sato, R.2
Brown, M.S.3
Hua, X.4
Goldstein, J.L.5
-
37
-
-
0343890977
-
Synthesis and destruction of cholesterol in the organism
-
R. Schoenheimer, and F. Breusch Synthesis and destruction of cholesterol in the organism J. Biol. Chem. 103 1933 439 448
-
(1933)
J. Biol. Chem.
, vol.103
, pp. 439-448
-
-
Schoenheimer, R.1
Breusch, F.2
-
38
-
-
0028657057
-
Somatic cell genetic analysis of two classes of CHO cell mutants expressing opposite phenotypes in sterol-dependent regulation of cholesterol metabolism
-
M.T. Hasan, and T.Y. Chang Somatic cell genetic analysis of two classes of CHO cell mutants expressing opposite phenotypes in sterol-dependent regulation of cholesterol metabolism Somat. Cell Mol. Genet. 20 6 1994 481 491
-
(1994)
Somat. Cell Mol. Genet.
, vol.20
, Issue.6
, pp. 481-491
-
-
Hasan, M.T.1
Chang, T.Y.2
-
40
-
-
0027261368
-
Loss of transcriptional activation of three sterol-regulated genes in mutant hamster cells
-
M.J. Evans, and J.E. Metherall Loss of transcriptional activation of three sterol-regulated genes in mutant hamster cells Mol. Cell. Biol. 13 9 1993 5175 5185 (Pubitemid 23260622)
-
(1993)
Molecular and Cellular Biology
, vol.13
, Issue.9
, pp. 5175-5185
-
-
Evans, M.J.1
Metherall, J.E.2
-
41
-
-
0017165502
-
Isolation and characterization of an unsaturated fatty acid-requiring mutant of cultured mammalian cells
-
T.Y. Chang, and P.R. Vagelos Isolation and characterization of an unsaturated fatty acid-requiring mutant of cultured mammalian cells Proc. Natl. Acad. Sci. U. S. A. 73 1 1976 24 28
-
(1976)
Proc. Natl. Acad. Sci. U. S. A.
, vol.73
, Issue.1
, pp. 24-28
-
-
Chang, T.Y.1
Vagelos, P.R.2
-
42
-
-
0032693671
-
Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress
-
K. Haze, H. Yoshida, H. Yanagi, T. Yura, and K. Mori Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress Mol. Biol. Cell 10 11 1999 3787 3799 (Pubitemid 29534025)
-
(1999)
Molecular Biology of the Cell
, vol.10
, Issue.11
, pp. 3787-3799
-
-
Haze, K.1
Yoshida, H.2
Yanagi, H.3
Yura, T.4
Mori, K.5
-
43
-
-
80054722420
-
The unfolded protein response: Integrating stress signals through the stress sensor IRE1α
-
C. Hetz, F. Martinon, D. Rodriguez, and L.H. Glimcher The unfolded protein response: integrating stress signals through the stress sensor IRE1α Physiol. Rev. 91 4 2011 1219 1243
-
(2011)
Physiol. Rev.
, vol.91
, Issue.4
, pp. 1219-1243
-
-
Hetz, C.1
Martinon, F.2
Rodriguez, D.3
Glimcher, L.H.4
-
44
-
-
12844257546
-
Stable binding of ATF6 to BiP in the endoplasmic reticulum stress response
-
DOI 10.1128/MCB.25.3.921-932.2005
-
J. Shen, E.L. Snapp, J. Lippincott-Schwartz, and R. Prywes Stable binding of ATF6 to BiP in the endoplasmic reticulum stress response Mol. Cell. Biol. 25 3 2005 921 932 (Pubitemid 40165801)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.3
, pp. 921-932
-
-
Shen, J.1
Snapp, E.L.2
Lippincott-Schwartz, J.3
Prywes, R.4
-
45
-
-
33847188475
-
BBF2H7, a novel transmembrane bZIP transcription factor, is a new type of endoplasmic reticulum stress transducer
-
S. Kondo, A. Saito, S. Hino, T. Murakami, M. Ogata, S. Kanemoto, S. Nara, A. Yamashita, K. Yoshinaga, H. Hara, and K. Imaizumi BBF2H7, a novel transmembrane bZIP transcription factor, is a new type of endoplasmic reticulum stress transducer Mol. Cell. Biol. 27 5 2007 1716 1729
-
(2007)
Mol. Cell. Biol.
, vol.27
, Issue.5
, pp. 1716-1729
-
-
Kondo, S.1
Saito, A.2
Hino, S.3
Murakami, T.4
Ogata, M.5
Kanemoto, S.6
Nara, S.7
Yamashita, A.8
Yoshinaga, K.9
Hara, H.10
Imaizumi, K.11
-
46
-
-
79954490167
-
Physiological unfolded protein response regulated by OASIS family members, transmembrane bZIP transcription factors
-
S. Kondo, A. Saito, R. Asada, S. Kanemoto, and K. Imaizumi Physiological unfolded protein response regulated by OASIS family members, transmembrane bZIP transcription factors IUBMB Life 63 4 2011 233 239
-
(2011)
IUBMB Life
, vol.63
, Issue.4
, pp. 233-239
-
-
Kondo, S.1
Saito, A.2
Asada, R.3
Kanemoto, S.4
Imaizumi, K.5
-
47
-
-
77950285163
-
Regulation of hepatic gluconeogenesis by an ER-bound transcription factor, CREBH
-
M.W. Lee, D. Chanda, J. Yang, H. Oh, S.S. Kim, Y.S. Yoon, S. Hong, K.G. Park, I.K. Lee, C.S. Choi, R.W. Hanson, H.S. Choi, and S.H. Koo Regulation of hepatic gluconeogenesis by an ER-bound transcription factor, CREBH Cell Metab. 11 4 2010 331 339
-
(2010)
Cell Metab.
, vol.11
, Issue.4
, pp. 331-339
-
-
Lee, M.W.1
Chanda, D.2
Yang, J.3
Oh, H.4
Kim, S.S.5
Yoon, Y.S.6
Hong, S.7
Park, K.G.8
Lee, I.K.9
Choi, C.S.10
Hanson, R.W.11
Choi, H.S.12
Koo, S.H.13
-
48
-
-
35949003194
-
Trafficking of the bZIP transmembrane transcription factor CREB-H into alternate pathways of ERAD and stress-regulated intramembrane proteolysis
-
DOI 10.1111/j.1600-0854.2007.00654.x
-
D. Bailey, C. Barreca, and P. O'Hare Trafficking of the bZIP transmembrane transcription factor CREB-H into alternate pathways of ERAD and stress-regulated intramembrane proteolysis Traffic 8 12 2007 1796 1814 (Pubitemid 350066690)
-
(2007)
Traffic
, vol.8
, Issue.12
, pp. 1796-1814
-
-
Bailey, D.1
Barreca, C.2
O'Hare, P.3
-
49
-
-
77953620910
-
DC-STAMP interacts with ER-resident transcription factor LUMAN which becomes activated during DC maturation
-
D. Eleveld-Trancikova, A. Sanecka, M.A. van Hout-Kuijer, M.W. Looman, I.A. Hendriks, B.J. Jansen, and G.J. Adema DC-STAMP interacts with ER-resident transcription factor LUMAN which becomes activated during DC maturation Mol. Immunol. 47 11-12 2010 1963 1973
-
(2010)
Mol. Immunol.
, vol.47
, Issue.1112
, pp. 1963-1973
-
-
Eleveld-Trancikova, D.1
Sanecka, A.2
Van Hout-Kuijer, M.A.3
Looman, M.W.4
Hendriks, I.A.5
Jansen, B.J.6
Adema, G.J.7
-
50
-
-
33645107263
-
Cleavage of the membrane-bound transcription factor OASIS in response to endoplasmic reticulum stress
-
T. Murakami, S. Kondo, M. Ogata, S. Kanemoto, A. Saito, A. Wanaka, and K. Imaizumi Cleavage of the membrane-bound transcription factor OASIS in response to endoplasmic reticulum stress J. Neurochem. 96 4 2006 1090 1100
-
(2006)
J. Neurochem.
, vol.96
, Issue.4
, pp. 1090-1100
-
-
Murakami, T.1
Kondo, S.2
Ogata, M.3
Kanemoto, S.4
Saito, A.5
Wanaka, A.6
Imaizumi, K.7
-
51
-
-
70349652275
-
Signalling mediated by the endoplasmic reticulum stress transducer OASIS is involved in bone formation
-
T. Murakami, A. Saito, S. Hino, S. Kondo, S. Kanemoto, K. Chihara, H. Sekiya, K. Tsumagari, K. Ochiai, K. Yoshinaga, M. Saitoh, R. Nishimura, T. Yoneda, I. Kou, T. Furuichi, S. Ikegawa, M. Ikawa, M. Okabe, A. Wanaka, and K. Imaizumi Signalling mediated by the endoplasmic reticulum stress transducer OASIS is involved in bone formation Nat. Cell Biol. 11 10 2009 1205 1211
-
(2009)
Nat. Cell Biol.
, vol.11
, Issue.10
, pp. 1205-1211
-
-
Murakami, T.1
Saito, A.2
Hino, S.3
Kondo, S.4
Kanemoto, S.5
Chihara, K.6
Sekiya, H.7
Tsumagari, K.8
Ochiai, K.9
Yoshinaga, K.10
Saitoh, M.11
Nishimura, R.12
Yoneda, T.13
Kou, I.14
Furuichi, T.15
Ikegawa, S.16
Ikawa, M.17
Okabe, M.18
Wanaka, A.19
Imaizumi, K.20
more..
-
52
-
-
64149125961
-
IFAP syndrome is caused by deficiency in MBTPS2, an intramembrane zinc metalloprotease essential for cholesterol homeostasis and ER stress response
-
F. Oeffner, G. Fischer, R. Happle, A. Konig, R.C. Betz, D. Bornholdt, U. Neidel, C. Boente Mdel, S. Redler, J. Romero-Gomez, A. Salhi, A. Vera-Casano, C. Weirich, and K.H. Grzeschik IFAP syndrome is caused by deficiency in MBTPS2, an intramembrane zinc metalloprotease essential for cholesterol homeostasis and ER stress response Am. J. Hum. Genet. 84 4 2009 459 467
-
(2009)
Am. J. Hum. Genet.
, vol.84
, Issue.4
, pp. 459-467
-
-
Oeffner, F.1
Fischer, G.2
Happle, R.3
Konig, A.4
Betz, R.C.5
Bornholdt, D.6
Neidel, U.7
Boente Mdel, C.8
Redler, S.9
Romero-Gomez, J.10
Salhi, A.11
Vera-Casano, A.12
Weirich, C.13
Grzeschik, K.H.14
-
53
-
-
79952116141
-
Keratosis follicularis spinulosa decalvans is caused by mutations in MBTPS2
-
E. Aten, L.C. Brasz, D. Bornholdt, I.B. Hooijkaas, M.E. Porteous, V.P. Sybert, M.H. Vermeer, R.H. Vossen, M.J. van der Wielen, E. Bakker, M.H. Breuning, K.H. Grzeschik, J.C. Oosterwijk, and J.T. den Dunnen Keratosis follicularis spinulosa decalvans is caused by mutations in MBTPS2 Hum. Mutat. 31 10 2010 1125 1133
-
(2010)
Hum. Mutat.
, vol.31
, Issue.10
, pp. 1125-1133
-
-
Aten, E.1
Brasz, L.C.2
Bornholdt, D.3
Hooijkaas, I.B.4
Porteous, M.E.5
Sybert, V.P.6
Vermeer, M.H.7
Vossen, R.H.8
Van Der Wielen, M.J.9
Bakker, E.10
Breuning, M.H.11
Grzeschik, K.H.12
Oosterwijk, J.C.13
Den Dunnen, J.T.14
-
54
-
-
26844482616
-
Dual roles for cholesterol in mammalian cells
-
DOI 10.1073/pnas.0503590102
-
F. Xu, S.D. Rychnovsky, J.D. Belani, H.H. Hobbs, J.C. Cohen, and R.B. Rawson Dual roles for cholesterol in mammalian cells Proc. Natl. Acad. Sci. U. S. A. 102 41 2005 14551 14556 (Pubitemid 41457095)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.41
, pp. 14551-14556
-
-
Xu, F.1
Rychnovsky, S.D.2
Belani, J.D.3
Hobbs, H.H.4
Cohen, J.C.5
Rawson, R.B.6
-
55
-
-
33744544947
-
Fatty acid auxotrophy in Drosophila larvae lacking SREBP
-
DOI 10.1016/j.cmet.2006.04.011, PII S1550413106001306
-
A.S. Kunte, K.A. Matthews, and R.B. Rawson Fatty acid auxotrophy in Drosophila larvae lacking SREBP Cell Metab. 3 6 2006 439 448 (Pubitemid 43811777)
-
(2006)
Cell Metabolism
, vol.3
, Issue.6
, pp. 439-448
-
-
Kunte, A.S.1
Matthews, K.A.2
Rawson, R.B.3
-
56
-
-
61549138703
-
Alternative processing of sterol regulatory element binding protein during larval development in Drosophila melanogaster
-
K.A. Matthews, A.S. Kunte, E. Tambe-Ebot, and R.B. Rawson Alternative processing of sterol regulatory element binding protein during larval development in Drosophila melanogaster Genetics 181 1 2009 119 128
-
(2009)
Genetics
, vol.181
, Issue.1
, pp. 119-128
-
-
Matthews, K.A.1
Kunte, A.S.2
Tambe-Ebot, E.3
Rawson, R.B.4
-
57
-
-
65649133944
-
Activation of sterol regulatory element-binding protein by the caspase Drice in Drosophila larvae
-
B. Amarneh, K.A. Matthews, and R.B. Rawson Activation of sterol regulatory element-binding protein by the caspase Drice in Drosophila larvae J. Biol. Chem. 284 15 2009 9674 9682
-
(2009)
J. Biol. Chem.
, vol.284
, Issue.15
, pp. 9674-9682
-
-
Amarneh, B.1
Matthews, K.A.2
Rawson, R.B.3
-
58
-
-
0028978248
-
Purification of an interleukin-1 beta converting enzyme-related cysteine protease that cleaves sterol regulatory element-binding proteins between the leucine zipper and transmembrane domains
-
X. Wang, J.T. Pai, E.A. Wiedenfeld, J.C. Medina, C.A. Slaughter, J.L. Goldstein, and M.S. Brown Purification of an interleukin-1 beta converting enzyme-related cysteine protease that cleaves sterol regulatory element-binding proteins between the leucine zipper and transmembrane domains J. Biol. Chem. 270 30 1995 18044 18050
-
(1995)
J. Biol. Chem.
, vol.270
, Issue.30
, pp. 18044-18050
-
-
Wang, X.1
Pai, J.T.2
Wiedenfeld, E.A.3
Medina, J.C.4
Slaughter, C.A.5
Goldstein, J.L.6
Brown, M.S.7
-
59
-
-
0029895343
-
Purification and cDNA cloning of a second apoptosis-related cysteine protease that cleaves and activates sterol regulatory element binding proteins
-
DOI 10.1073/pnas.93.11.5437
-
J.T. Pai, M.S. Brown, and J.L. Goldstein Purification and cDNA cloning of a second apoptosis-related cysteine protease that cleaves and activates sterol regulatory element binding proteins Proc. Natl. Acad. Sci. U. S. A. 93 11 1996 5437 5442 (Pubitemid 26159468)
-
(1996)
Proceedings of the National Academy of Sciences of the United States of America
, vol.93
, Issue.11
, pp. 5437-5442
-
-
Pai, J.-T.1
Brown, M.S.2
Goldstein, J.L.3
-
60
-
-
0036315042
-
Luman, the cellular counterpart of herpes simplex virus VP16, is processed by regulated intramembrane proteolysis
-
DOI 10.1128/MCB.22.16.5639-5649.2002
-
C. Raggo, N. Rapin, J. Stirling, P. Gobeil, E. Smith-Windsor, P. O'Hare, and V. Misra Luman, the cellular counterpart of herpes simplex virus VP16, is processed by regulated intramembrane proteolysis Mol. Cell. Biol. 22 16 2002 5639 5649 (Pubitemid 34815814)
-
(2002)
Molecular and Cellular Biology
, vol.22
, Issue.16
, pp. 5639-5649
-
-
Raggo, C.1
Rapin, N.2
Stirling, J.3
Gobeil, P.4
Smith-Windsor, E.5
O'Hare, P.6
Misra, V.7
-
61
-
-
52049095050
-
CREB3L2-PPARgamma fusion mutation identifies a thyroid signaling pathway regulated by intramembrane proteolysis
-
W.O. Lui, L. Zeng, V. Rehrmann, S. Deshpande, M. Tretiakova, E.L. Kaplan, I. Leibiger, B. Leibiger, U. Enberg, A. Hoog, C. Larsson, and T.G. Kroll CREB3L2-PPARgamma fusion mutation identifies a thyroid signaling pathway regulated by intramembrane proteolysis Cancer Res. 68 17 2008 7156 7164
-
(2008)
Cancer Res.
, vol.68
, Issue.17
, pp. 7156-7164
-
-
Lui, W.O.1
Zeng, L.2
Rehrmann, V.3
Deshpande, S.4
Tretiakova, M.5
Kaplan, E.L.6
Leibiger, I.7
Leibiger, B.8
Enberg, U.9
Hoog, A.10
Larsson, C.11
Kroll, T.G.12
-
62
-
-
30044441047
-
CREB4, a transmembrane bZip transcription factor and potential new substrate for regulation and cleavage by S1P
-
DOI 10.1091/mbc.E05-06-0500
-
J. Stirling, and P. O'Hare CREB4, a transmembrane bZip transcription factor and potential new substrate for regulation and cleavage by S1P Mol. Biol. Cell 17 1 2006 413 426 (Pubitemid 43049493)
-
(2006)
Molecular Biology of the Cell
, vol.17
, Issue.1
, pp. 413-426
-
-
Stirling, J.1
O'Hare, P.2
-
63
-
-
35548990261
-
Transcriptional profiling of genes that are regulated by the endoplasmic reticulum-bound transcription factor AIbZIP/CREB3L4 in prostate cells
-
DOI 10.1152/physiolgenomics.00097.2007
-
S. Ben Aicha, J. Lessard, M. Pelletier, A. Fournier, E. Calvo, and C. Labrie Transcriptional profiling of genes that are regulated by the endoplasmic reticulum-bound transcription factor AIbZIP/CREB3L4 in prostate cells Physiol. Genomics 31 2 2007 295 305 (Pubitemid 350014407)
-
(2007)
Physiological Genomics
, vol.31
, Issue.2
, pp. 295-305
-
-
Aicha, S.B.1
Lessard, J.2
Pelletier, M.3
Fournier, A.4
Calvo, E.5
Labrie, C.6
-
64
-
-
63649142567
-
Rhomboids: 7 years of a new protease family
-
M. Freeman Rhomboids: 7 years of a new protease family Semin. Cell Dev. Biol. 20 2 2009 231 239
-
(2009)
Semin. Cell Dev. Biol.
, vol.20
, Issue.2
, pp. 231-239
-
-
Freeman, M.1
-
65
-
-
80054893675
-
The rhomboid protease family: A decade of progress on function and mechanism
-
S. Urban, and S.W. Dickey The rhomboid protease family: a decade of progress on function and mechanism Genome Biol. 12 10 2011 231 241
-
(2011)
Genome Biol.
, vol.12
, Issue.10
, pp. 231-241
-
-
Urban, S.1
Dickey, S.W.2
-
66
-
-
0035830840
-
Unsaturated fatty acids down-regulate srebp isoforms 1a and 1c by two mechanisms in HEK-293 cells
-
V.C. Hannah, J. Ou, A. Luong, J.L. Goldstein, and M.S. Brown Unsaturated fatty acids down-regulate srebp isoforms 1a and 1c by two mechanisms in HEK-293 cells J. Biol. Chem. 276 6 2001 4365 4372
-
(2001)
J. Biol. Chem.
, vol.276
, Issue.6
, pp. 4365-4372
-
-
Hannah, V.C.1
Ou, J.2
Luong, A.3
Goldstein, J.L.4
Brown, M.S.5
-
67
-
-
77956633770
-
Activation of sterol regulatory element binding proteins in the absence of Scap in Drosophila melanogaster
-
K.A. Matthews, C. Ozdemir, and R.B. Rawson Activation of sterol regulatory element binding proteins in the absence of Scap in Drosophila melanogaster Genetics 185 1 2010 189 198
-
(2010)
Genetics
, vol.185
, Issue.1
, pp. 189-198
-
-
Matthews, K.A.1
Ozdemir, C.2
Rawson, R.B.3
|