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Volumn 3, Issue 10, 2013, Pages

Antibiotic and anti-inflammatory therapies for cystic fibrosis

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; ANTIINFLAMMATORY AGENT; ANTIOXIDANT; CORTICOSTEROID; CYTOKINE; IBUPROFEN; ICOSANOID; PROTEINASE INHIBITOR;

EID: 84885040441     PISSN: None     EISSN: 21571422     Source Type: Journal    
DOI: 10.1101/cshperspect.a009779     Document Type: Article
Times cited : (54)

References (107)
  • 2
    • 0029010510 scopus 로고
    • Lower respiratory infection and inflammation in infants with newly diagnosed cystic fi-brosis
    • Armstrong DS, Grimwood K, Carzino R, Carlin JB, Olin-sky A, Phelan PD. 1995. Lower respiratory infection and inflammation in infants with newly diagnosed cystic fi-brosis. BMJ 310: 1571-1572.
    • (1995) BMJ , vol.310 , pp. 1571-1572
    • Armstrong, D.S.1    Grimwood, K.2    Carzino, R.3    Carlin, J.B.4    Olin-Sky, A.5    Phelan, P.D.6
  • 4
    • 0021970474 scopus 로고
    • Alternate-day prednisone reduces morbidity and improves pulmonary function in cystic fibrosis
    • Auerbach HS, Williams M, Kirkpatrick JA, Colten HR. 1985. Alternate-day prednisone reduces morbidity and improves pulmonary function in cystic fibrosis. Lancet 2: 686-688.
    • (1985) Lancet , vol.2 , pp. 686-688
    • Auerbach, H.S.1    Williams, M.2    Kirkpatrick, J.A.3    Colten, H.R.4
  • 5
  • 6
    • 33745130682 scopus 로고    scopus 로고
    • Multicenter randomized controlled trial of withdrawal of inhaled cor-ticosteroids in cystic fibrosis
    • CF WISE (Withdrawal of Inhaled Steroids Evaluation) Investigators
    • Balfour-Lynn IM, Lees B, Hall P, Phillips G, Khan M, Fla-ther M, Elborn JS, CF WISE (Withdrawal of Inhaled Steroids Evaluation) Investigators. 2006. Multicenter randomized controlled trial of withdrawal of inhaled cor-ticosteroids in cystic fibrosis. Am J Respir Crit Care Med 173: 1356-1362.
    • (2006) Am J Respir Crit Care Med , vol.173 , pp. 1356-1362
    • Balfour-Lynn, I.M.1    Lees, B.2    Hall, P.3    Phillips, G.4    Khan, M.5    Fla-Ther, M.6    Elborn, J.S.7
  • 7
    • 0037406477 scopus 로고    scopus 로고
    • Low-dose methotrexate for advanced pulmonarydiseasein patients with cystic fibrosis
    • Ballmann M, Junge S, von der Hardt H. 2003. Low-dose methotrexate for advanced pulmonarydiseasein patients with cystic fibrosis. Respir Med 97: 498-500.
    • (2003) Respir Med , vol.97 , pp. 498-500
    • Ballmann, M.1    Junge, S.2    von der Hardt, H.3
  • 8
    • 0029346937 scopus 로고
    • The relationship between infection and inflammation in the early stages of lung disease from cystic fibrosis
    • Balough K, McCubbin M, Weinberger M, Smits W, Ahrens R, Fick R. 1995. The relationship between infection and inflammation in the early stages of lung disease from cystic fibrosis. Pediatr Pulmonol 20: 63-70.
    • (1995) Pediatr Pulmonol , vol.20 , pp. 63-70
    • Balough, K.1    McCubbin, M.2    Weinberger, M.3    Smits, W.4    Ahrens, R.5    Fick, R.6
  • 11
    • 0035168113 scopus 로고    scopus 로고
    • Use of cyclosporin A as a steroid sparing agent in cystic fibrosis
    • Bhal GK, Maguire SA, Bowler IM. 2001. Use of cyclosporin A as a steroid sparing agent in cystic fibrosis. Arch Dis Child 84: 89.
    • (2001) Arch Dis Child , vol.84 , pp. 89
    • Bhal, G.K.1    Maguire, S.A.2    Bowler, I.M.3
  • 12
    • 13644282540 scopus 로고    scopus 로고
    • Phase II trial to assess the clinical efficacy of transgenic a-1-antitrypsin (tg-hAAT) as an effective treatment of cystic fibrosis
    • Bilton D, Elborn S, Conway S, Edgar J, Redmond A. 1999. Phase II trial to assess the clinical efficacy of transgenic a-1-antitrypsin (tg-hAAT) as an effective treatment of cystic fibrosis. Pediatr Pulmonol 28 (Suppl 19): 246.
    • (1999) Pediatr Pulmonol , vol.28 , Issue.SUPPL. 19 , pp. 246
    • Bilton, D.1    Elborn, S.2    Conway, S.3    Edgar, J.4    Redmond, A.5
  • 14
    • 13844322148 scopus 로고    scopus 로고
    • A pilot study of the effects of inhaled buffered reduced glutathi-one on the clinical status of patients with cystic fibrosis
    • Bishop C, Hudson VM, Hilton SC, Wilde C. 2005. A pilot study of the effects of inhaled buffered reduced glutathi-one on the clinical status of patients with cystic fibrosis. Chest 127: 308-317.
    • (2005) Chest , vol.127 , pp. 308-317
    • Bishop, C.1    Hudson, V.M.2    Hilton, S.C.3    Wilde, C.4
  • 16
    • 0029372481 scopus 로고
    • Normal bronchial epithelial cells constitutively produce the anti-inflammatory cytokine interleukin-10, which is downregulated in cystic fibrosis
    • Bonfield TL, Konstan MW, Burfeind P, Panuska JR, Hilli-ard JB, Berger M. 1995b. Normal bronchial epithelial cells constitutively produce the anti-inflammatory cytokine interleukin-10, which is downregulated in cystic fibrosis. Am J Respir Cell Mol Biol 13: 257-261.
    • (1995) Am J Respir Cell Mol Biol , vol.13 , pp. 257-261
    • Bonfield, T.L.1    Konstan, M.W.2    Burfeind, P.3    Panuska, J.R.4    Hilli-Ard, J.B.5    Berger, M.6
  • 17
    • 0032817772 scopus 로고    scopus 로고
    • Altered respiratory epithelial cell cytokine production in cystic fibrosis
    • Bonfield TL, Konstan MW, Berger M. 1999. Altered respiratory epithelial cell cytokine production in cystic fibrosis. J Allergy Clin Immunol 104: 72-78.
    • (1999) J Allergy Clin Immunol , vol.104 , pp. 72-78
    • Bonfield, T.L.1    Konstan, M.W.2    Berger, M.3
  • 19
    • 1542267080 scopus 로고    scopus 로고
    • State of the art: Why do the lungs of patients with cystic fibrosis become infected and why can't they clear the infection?
    • Chmiel JF, Davis PB. 2003. State of the art: Why do the lungs of patients with cystic fibrosis become infected and why can't they clear the infection? Respir Res 4: 8-21.
    • (2003) Respir Res , vol.4 , pp. 8-21
    • Chmiel, J.F.1    Davis, P.B.2
  • 21
    • 0035991525 scopus 로고    scopus 로고
    • The role of inflammation in the pathophysiology of CF lung disease
    • Chmiel JF, Konstan MW, Berger M. 2002a. The role of inflammation in the pathophysiology of CF lung disease. Clin Review Allergy Immunol 23: 5-27.
    • (2002) Clin Review Allergy Immunol , vol.23 , pp. 5-27
    • Chmiel, J.F.1    Konstan, M.W.2    Berger, M.3
  • 24
    • 77953635880 scopus 로고    scopus 로고
    • Association between respiratory tract methicillin-resistant Staphylococcus aureus and survival in cystic fibrosis
    • Dasenbrook EC, Checkley W, Merlo CA, Konstan MW, Lechtzin N, Boyle MP. 2010. Association between respiratory tract methicillin-resistant Staphylococcus aureus and survival in cystic fibrosis. JAMA 303: 2386-2392.
    • (2010) JAMA , vol.303 , pp. 2386-2392
    • Dasenbrook, E.C.1    Checkley, W.2    Merlo, C.A.3    Konstan, M.W.4    Lechtzin, N.5    Boyle, M.P.6
  • 26
    • 62949129940 scopus 로고    scopus 로고
    • Inhibition of proinflammatory cytokine production by PPARg agonists in airway epithelial cells
    • Davis PB, Gupta S, Eastman J, Konstan MW. 2003. Inhibition of proinflammatory cytokine production by PPARg agonists in airway epithelial cells. Pediatr Pulmonol 36 (Suppl 25): 268-269.
    • (2003) Pediatr Pulmonol , vol.36 , Issue.SUPPL. 25 , pp. 268-269
    • Davis, P.B.1    Gupta, S.2    Eastman, J.3    Konstan, M.W.4
  • 27
    • 79955667134 scopus 로고    scopus 로고
    • Inhaled corticoste-roids and lower lung function decline in young children with cystic fibrosis
    • Members of the Belgian CF Registry
    • De Boeck K, Vermeulen F, Wanyama S, Thomas M, Members of the Belgian CF Registry. 2011. Inhaled corticoste-roids and lower lung function decline in young children with cystic fibrosis. Eur Respir J 37: 1091-1095.
    • (2011) Eur Respir J , vol.37 , pp. 1091-1095
    • de Boeck, K.1    Vermeulen, F.2    Wanyama, S.3    Thomas, M.4
  • 28
    • 84869120178 scopus 로고    scopus 로고
    • Treatment of lung infection in patients with cystic fibrosis: Current and future strategies
    • Consensus Study Group
    • Döring G, Flume P, Heijerman H, Elborn JS, Consensus Study Group. 2012. Treatment of lung infection in patients with cystic fibrosis: Current and future strategies. J Cyst Fibros 2012 11: 461-479.
    • (2012) J Cyst Fibros , vol.2012 , Issue.11 , pp. 461-479
    • Döring, G.1    Flume, P.2    Heijerman, H.3    Elborn, J.S.4
  • 29
    • 33847043963 scopus 로고    scopus 로고
    • IL-23 mediates inflammatory responses to mucoid Pseudomonas aeruginosa lung infection in mice
    • Dubin PJ, Kolls JK. 2007. IL-23 mediates inflammatory responses to mucoid Pseudomonas aeruginosa lung infection in mice. Am J Physiol Lung Cell Mol Physiol 292: L519-L528.
    • (2007) Am J Physiol Lung Cell Mol Physiol , vol.292
    • Dubin, P.J.1    Kolls, J.K.2
  • 31
    • 0030814892 scopus 로고    scopus 로고
    • Mevalonate-de-pendent inhibition of transendothelial migration and chemotaxis of human peripheral blood neutrophils by pravastatin
    • Dunzendorfer S, Rothbucher D, Schratzberger P, Reinisch N, Kahler CM, Wiedermann CJ. 1997. Mevalonate-de-pendent inhibition of transendothelial migration and chemotaxis of human peripheral blood neutrophils by pravastatin. Circ Res 81: 963-969.
    • (1997) Circ Res , vol.81 , pp. 963-969
    • Dunzendorfer, S.1    Rothbucher, D.2    Schratzberger, P.3    Reinisch, N.4    Kahler, C.M.5    Wiedermann, C.J.6
  • 32
    • 0028969594 scopus 로고
    • A multicenter study of alternate-day prednisone therapy in patientswith cysticfibrosis
    • Cystic Fibrosis Foundation Prednisone Trial Group
    • Eigen H, Rosenstein BJ, FitzSimmons S, Schidlow DV. 1995. A multicenter study of alternate-day prednisone therapy in patientswith cysticfibrosis. Cystic Fibrosis Foundation Prednisone Trial Group. J Pediatr 126: 515-523.
    • (1995) J Pediatr , vol.126 , pp. 515-523
    • Eigen, H.1    Rosenstein, B.J.2    Fitzsimmons, S.3    Schidlow, D.V.4
  • 33
    • 0037442137 scopus 로고    scopus 로고
    • IL-17, produced by lymphocytes and neutrophils, is necessary for lipopolysaccharide-induced airway neu-trophilia: IL-15 as a possible trigger
    • Ferretti S, Bonneau O, Dubois GR, Jones CE, Trifilieff A. 2003. IL-17, produced by lymphocytes and neutrophils, is necessary for lipopolysaccharide-induced airway neu-trophilia: IL-15 as a possible trigger. J Immunol 170: 2106-2112.
    • (2003) J Immunol , vol.170 , pp. 2106-2112
    • Ferretti, S.1    Bonneau, O.2    Dubois, G.R.3    Jones, C.E.4    Trifilieff, A.5
  • 37
    • 0030961127 scopus 로고    scopus 로고
    • Decreased concentration of exhaled nitric oxide (NO) in patients with cystic fibrosis
    • Grasemann H, Michler E, Wallot M, Ratjen F. 1997. Decreased concentration of exhaled nitric oxide (NO) in patients with cystic fibrosis. Pediatr Pulmonol 24: 173-177.
    • (1997) Pediatr Pulmonol , vol.24 , pp. 173-177
    • Grasemann, H.1    Michler, E.2    Wallot, M.3    Ratjen, F.4
  • 43
    • 33744461829 scopus 로고    scopus 로고
    • Anti-inflammatory effect of augmented nitric oxide production in chronic lung infection
    • Hopkins N, Gunning Y, O'Croinin DF, Laffey JG, Mc-Loughlin P. 2006. Anti-inflammatory effect of augmented nitric oxide production in chronic lung infection. J Pathol 209: 198-205.
    • (2006) J Pathol , vol.209 , pp. 198-205
    • Hopkins, N.1    Gunning, Y.2    O'Croinin, D.F.3    Laffey, J.G.4    Mc-Loughlin, P.5
  • 44
    • 0030802906 scopus 로고    scopus 로고
    • Pulmonary oxidative stress response in young children with cystic fibrosis
    • Hull J, Vervaart P, Grimwood K, Phelan P. 1997. Pulmonary oxidative stress response in young children with cystic fibrosis. Thorax 52: 557-560.
    • (1997) Thorax , vol.52 , pp. 557-560
    • Hull, J.1    Vervaart, P.2    Grimwood, K.3    Phelan, P.4
  • 46
    • 0032531160 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase expression is reduced in cystic fibrosis murine and human airway epithelial cells
    • Kelley TJ, Drumm ML. 1998. Inducible nitric oxide synthase expression is reduced in cystic fibrosis murine and human airway epithelial cells. J Clin Invest 102: 1200-1207.
    • (1998) J Clin Invest , vol.102 , pp. 1200-1207
    • Kelley, T.J.1    Drumm, M.L.2
  • 49
    • 55149093388 scopus 로고    scopus 로고
    • Ibuprofen therapy for cystic fibrosis lung disease: Revisited
    • Konstan MW. 2008. Ibuprofen therapy for cystic fibrosis lung disease: Revisited. Curr Opin Pulm Med 14: 567-573.
    • (2008) Curr Opin Pulm Med , vol.14 , pp. 567-573
    • Konstan, M.W.1
  • 50
    • 0030881846 scopus 로고    scopus 로고
    • Current understanding of the inflammatory process in cystic fibrosis-Onset and etiology
    • Konstan MW, Berger M. 1997. Current understanding of the inflammatory process in cystic fibrosis-Onset and etiology. Pediatr Pulmonol 24: 137-142.
    • (1997) Pediatr Pulmonol , vol.24 , pp. 137-142
    • Konstan, M.W.1    Berger, M.2
  • 51
    • 0027682586 scopus 로고
    • Leukotriene B4 is markedly elevated in the epithelial lining fluidof patients with cystic fibrosis
    • Konstan MW, Walenga RW, Hilliard KA, Hilliard JB. 1993. Leukotriene B4 is markedly elevated in the epithelial lining fluidof patients with cystic fibrosis. Am Rev Respir Dis 148: 896-901.
    • (1993) Am Rev Respir Dis , vol.148 , pp. 896-901
    • Konstan, M.W.1    Walenga, R.W.2    Hilliard, K.A.3    Hilliard, J.B.4
  • 52
    • 0028015883 scopus 로고
    • Bronchoalveolar lavage findings in cystic fibrosis patients with stable, clinically mild lung disease suggest ongoing infection and inflammation
    • Konstan MW, Hilliard KA, Norvell TM, Berger M. 1994. Bronchoalveolar lavage findings in cystic fibrosis patients with stable, clinically mild lung disease suggest ongoing infection and inflammation. Am J Respir Crit Care Med 150: 448-454.
    • (1994) Am J Respir Crit Care Med , vol.150 , pp. 448-454
    • Konstan, M.W.1    Hilliard, K.A.2    Norvell, T.M.3    Berger, M.4
  • 53
    • 0028914667 scopus 로고
    • Effect of high-dose ibuprofen in patients with cystic fibrosis
    • Konstan MW, Byard PJ, Hoppel CL, Davis PB. 1995. Effect of high-dose ibuprofen in patients with cystic fibrosis. N Engl J Med 332: 848-854.
    • (1995) N Engl J Med , vol.332 , pp. 848-854
    • Konstan, M.W.1    Byard, P.J.2    Hoppel, C.L.3    Davis, P.B.4
  • 56
    • 36848999782 scopus 로고    scopus 로고
    • Clinical use of ibuprofen is associated with slower FEV1 decline in children with cystic fibrosis
    • Konstan MW, Schluchter MD, Xue W, Davis PB. 2007. Clinical use of ibuprofen is associated with slower FEV1 decline in children with cystic fibrosis. Am J Respir Crit Care Med 176: 1084-1089.
    • (2007) Am J Respir Crit Care Med , vol.176 , pp. 1084-1089
    • Konstan, M.W.1    Schluchter, M.D.2    Xue, W.3    Davis, P.B.4
  • 57
    • 84886091119 scopus 로고    scopus 로고
    • A pilot study evaluating the effect of pioglitazone, simvastatin, and ibuprofen on neutrophil migration in vivo in healthy subjects
    • Konstan M, Krenicky J, Hilliard K, Hilliard J. 2009. A pilot study evaluating the effect of pioglitazone, simvastatin, and ibuprofen on neutrophil migration in vivo in healthy subjects. Pediatr Pulmonol 44 (Suppl 32): 289-290.
    • (2009) Pediatr Pulmonol , vol.44 , Issue.SUPPL. 32 , pp. 289-290
    • Konstan, M.1    Krenicky, J.2    Hilliard, K.3    Hilliard, J.4
  • 62
    • 44949151079 scopus 로고    scopus 로고
    • Oral non-steroidal anti-inflammatory drug therapy for cystic fibrosis
    • Lands L, Stanojevic S. 2007. Oral non-steroidal anti-inflammatory drug therapy for cystic fibrosis. Cochrane Database Syst Rev 17: CD001505.
    • (2007) Cochrane Database Syst Rev , vol.17
    • Lands, L.1    Stanojevic, S.2
  • 63
    • 34548038663 scopus 로고    scopus 로고
    • High-dose ibuprofen in cystic fibrosis: Canadian safety and effectiveness trial
    • Lands LC, Milner R, Cantin AM, Manson D, Corey M. 2007. High-dose ibuprofen in cystic fibrosis: Canadian safety and effectiveness trial. J Pediatr 151: 228-230.
    • (2007) J Pediatr , vol.151 , pp. 228-230
    • Lands, L.C.1    Milner, R.2    Cantin, A.M.3    Manson, D.4    Corey, M.5
  • 64
    • 79959340752 scopus 로고    scopus 로고
    • SB-656933, a novel CXCR2 selective antagonist, inhibits ex vivo neutrophil activation and ozone-induced airway inflammation in humans
    • Lazaar AL, Sweeney LE, MacDonald AJ, Alexis NE, Chen C, Tal-Singer R. 2011. SB-656933, a novel CXCR2 selective antagonist, inhibits ex vivo neutrophil activation and ozone-induced airway inflammation in humans. Br J Clin Pharmacol 72: 282-293.
    • (2011) Br J Clin Pharmacol , vol.72 , pp. 282-293
    • Lazaar, A.L.1    Sweeney, L.E.2    Macdonald, A.J.3    Alexis, N.E.4    Chen, C.5    Tal-Singer, R.6
  • 65
    • 0031851457 scopus 로고    scopus 로고
    • Glutathione permeability of CFTR
    • Linsdell P, Hanrahan JW. 1998. Glutathione permeability of CFTR. Am J Physiol 275 (Pt 1): C323-C326.
    • (1998) Am J Physiol , vol.275 , Issue.PART 1
    • Linsdell, P.1    Hanrahan, J.W.2
  • 66
    • 77950682572 scopus 로고    scopus 로고
    • The changing microbial epidemiology in CF
    • LiPuma J. 2010. The changing microbial epidemiology in CF. Clin Microbiol Rev 23: 299-323.
    • (2010) Clin Microbiol Rev , vol.23 , pp. 299-323
    • Lipuma, J.1
  • 67
    • 84866063949 scopus 로고    scopus 로고
    • The new microbiology of cystic fibrosis: It takes a community
    • LiPuma J. 2012. The new microbiology of cystic fibrosis: It takes a community. Thorax 67: 851-852.
    • (2012) Thorax , vol.67 , pp. 851-852
    • Lipuma, J.1
  • 68
    • 21244455537 scopus 로고    scopus 로고
    • Role of IL-17A, IL-17F, and the IL-17 receptor in regulating growth related oncogene-a and granulocyte colony-stimulating factor in bronchial epithelium: Implications for airway inflammation in cystic fibrosis
    • McAllister F, Henry A, Kreindler JL, Dubin PJ, Ulrich L, Steele C, Finder JD, Pilewski JM, Carreno BM, Goldman SJ, et al. 2005. Role of IL-17A, IL-17F, and the IL-17 receptor in regulating growth related oncogene-a and granulocyte colony-stimulating factor in bronchial epithelium: Implications for airway inflammation in cystic fibrosis. J Immunol 175: 404-412.
    • (2005) J Immunol , vol.175 , pp. 404-412
    • McAllister, F.1    Henry, A.2    Kreindler, J.L.3    Dubin, P.J.4    Ulrich, L.5    Steele, C.6    Finder, J.D.7    Pilewski, J.M.8    Carreno, B.M.9    Goldman, S.J.10
  • 70
    • 0027495712 scopus 로고
    • Pharmacokinetics of recombinant secretory leukoprotease inhibitor aerosolized to normals and individuals with cystic fibrosis
    • McElvaney NG, Doujaiji B, Moan MJ, Burnham MR, Wu MC, Crystal RG. 1993. Pharmacokinetics of recombinant secretory leukoprotease inhibitor aerosolized to normals and individuals with cystic fibrosis. Am Rev Respir Dis 148 (Pt 1): 1056-1060.
    • (1993) Am Rev Respir Dis , vol.148 , Issue.PART 1 , pp. 1056-1060
    • McElvaney, N.G.1    Doujaiji, B.2    Moan, M.J.3    Burnham, M.R.4    Wu, M.C.5    Crystal, R.G.6
  • 72
    • 20144387174 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled, dose-escalating studyof aerosolized inter-feron g-1b in patients with mild to moderate cystic fibro-sis lung disease
    • Moss RB, Mayer-Hamblett N, Wagener J, Daines C, Hale K, Ahrens R, Gibson RL, Anderson P, Retsch-Bogart G, Nasr SZ, et al. 2005. Randomized, double-blind, placebo-controlled, dose-escalating studyof aerosolized inter-feron g-1b in patients with mild to moderate cystic fibro-sis lung disease. Pediatr Pulmonol 39: 209-218.
    • (2005) Pediatr Pulmonol , vol.39 , pp. 209-218
    • Moss, R.B.1    Mayer-Hamblett, N.2    Wagener, J.3    Daines, C.4    Hale, K.5    Ahrens, R.6    Gibson, R.L.7    Anderson, P.8    Retsch-Bogart, G.9    Nasr, S.Z.10
  • 73
    • 84885086048 scopus 로고    scopus 로고
    • Safety and early treatment effects of the CXCR2 antagonist SB-656933 in patients with cystic fibrosis
    • for the CF2110399 Investigators, pii: S1569-1993(12)00155-5
    • Moss RB, Mistry SJ, Konstan MW, Pilewski JM, Kerem E, Tal-Singer R, Lazaar AL, for the CF2110399 Investigators. 2012. Safety and early treatment effects of the CXCR2 antagonist SB-656933 in patients with cystic fibrosis. J Cyst Fibros pii: S1569-1993(12)00155-5
    • (2012) J Cyst Fibros
    • Moss, R.B.1    Mistry, S.J.2    Konstan, M.W.3    Pilewski, J.M.4    Kerem, E.5    Tal-Singer, R.6    Lazaar, A.L.7
  • 74
    • 0032770489 scopus 로고    scopus 로고
    • Quantitation of inflammatory response to bacteria in young cystic fibrosis and control patients
    • Muhlebach MS, PW Stewart, Leigh MW, Noah TL. 1999. Quantitation of inflammatory response to bacteria in young cystic fibrosis and control patients. Am J Respir Crit Care Med 160: 186-191.
    • (1999) Am J Respir Crit Care Med , vol.160 , pp. 186-191
    • Muhlebach, M.S.1    Stewart, P.W.2    Leigh, M.W.3    Noah, T.L.4
  • 76
    • 0031035884 scopus 로고    scopus 로고
    • Nasal and bronchoalveolar lavage fluid cytokines in early cystic fibrosis
    • Noah TL, Black HR, Cheng PW, Wood RE, Leigh MW. 1997. Nasal and bronchoalveolar lavage fluid cytokines in early cystic fibrosis. J Infect Dis 175: 638-647.
    • (1997) J Infect Dis , vol.175 , pp. 638-647
    • Noah, T.L.1    Black, H.R.2    Cheng, P.W.3    Wood, R.E.4    Leigh, M.W.5
  • 77
    • 84886086446 scopus 로고    scopus 로고
    • A pilot studyevaluating the potential useoflow-dose meth-otrexate as an anti-inflammatory therapy for cystic fibro-sis lung disease
    • Oermann CM, Katz M, Wheeler C, Cumming S. 2007. A pilot studyevaluating the potential useoflow-dose meth-otrexate as an anti-inflammatory therapy for cystic fibro-sis lung disease. Pediatr Pulmonol 42 (Suppl 30): 292-293.
    • (2007) Pediatr Pulmonol , vol.42 , Issue.SUPPL. 30 , pp. 292-293
    • Oermann, C.M.1    Katz, M.2    Wheeler, C.3    Cumming, S.4
  • 79
    • 84856731944 scopus 로고    scopus 로고
    • Incidence and risk factors for pulmonary exacerbation treatment failures in cystic fibrosis patients chronically infected with Pseudo-monas aeruginosa
    • Parkins MD, Rendall JC, Elborn JS. 2012. Incidence and risk factors for pulmonary exacerbation treatment failures in cystic fibrosis patients chronically infected with Pseudo-monas aeruginosa. Chest 141: 485-493.
    • (2012) Chest , vol.141 , pp. 485-493
    • Parkins, M.D.1    Rendall, J.C.2    Elborn, J.S.3
  • 81
    • 84870742117 scopus 로고    scopus 로고
    • Comparisonof two treatment regimens for eradication of P. aeruginosa infection in children with cystic fibrosis
    • Proesmans M. 2013. Comparisonof two treatment regimens for eradication of P. aeruginosa infection in children with cystic fibrosis. J Cyst Fibros 12: 29-34.
    • (2013) J Cyst Fibros , vol.12 , pp. 29-34
    • Proesmans, M.1
  • 82
    • 77950914953 scopus 로고    scopus 로고
    • Treatment of early Pseudomonas aeruginosa infec tion in patients with cystic fibrosis: The ELITE trial
    • ELITE Study Group
    • Ratjen F, Munck A, Kho P, Angyalosi G, ELITE Study Group. 2010. Treatment of early Pseudomonas aeruginosa infec tion in patients with cystic fibrosis: The ELITE trial. Tho rax 65: 286-291.
    • (2010) Tho Rax , vol.65 , pp. 286-291
    • Ratjen, F.1    Munck, A.2    Kho, P.3    Angyalosi, G.4
  • 83
    • 56049085357 scopus 로고    scopus 로고
    • Relationship between inhaled corticoste-roid therapy and rate of lung function decline in children with cystic fibrosis
    • Scientific Advisory Group the Investigators and Coordinators of the Epidemiologic Study of Cystic Fibrosis
    • Ren CL, Pasta DJ, Rasouliyan L, Wagener JS, Konstan MW, Morgan WJ, Scientific Advisory Group the Investigators and Coordinators of the Epidemiologic Study of Cystic Fibrosis. 2008. Relationship between inhaled corticoste-roid therapy and rate of lung function decline in children with cystic fibrosis. J Pediatr 153: 746-751.
    • (2008) J Pediatr , vol.153 , pp. 746-751
    • Ren, C.L.1    Pasta, D.J.2    Rasouliyan, L.3    Wagener, J.S.4    Konstan, M.W.5    Morgan, W.J.6
  • 84
    • 0036066345 scopus 로고    scopus 로고
    • Simvastatin reduces expression of cytokines inter-leukin-6, interleukin-8, and monocyte chemoattractant protein-1 in circulating monocytes from hypercholester-olemic patients
    • Rezaie-Majd A, Maca T, Bucek RA, Valent P, Müller MR, Husslein P, Kashanipour A, Minar E, Baghestanian M. 2002. Simvastatin reduces expression of cytokines inter-leukin-6, interleukin-8, and monocyte chemoattractant protein-1 in circulating monocytes from hypercholester-olemic patients. Arterioscler Thromb Vasc Biol 22: 1194-1199.
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , pp. 1194-1199
    • Rezaie-Majd, A.1    Maca, T.2    Bucek, R.A.3    Valent, P.4    Müller, M.R.5    Husslein, P.6    Kashanipour, A.7    Minar, E.8    Baghestanian, M.9
  • 85
    • 62949240359 scopus 로고    scopus 로고
    • The role of inhaled corticosteroids in the management of cystic fibrosis
    • Ross KR, Chmiel JF, Konstan MW. 2009. The role of inhaled corticosteroids in the management of cystic fibrosis. Paediatr Drugs 11: 101-113.
    • (2009) Paediatr Drugs , vol.11 , pp. 101-113
    • Ross, K.R.1    Chmiel, J.F.2    Konstan, M.W.3
  • 87
    • 0042867242 scopus 로고    scopus 로고
    • Troglitazone antagonizes tumor necrosis factor-a-induced reprogramming of adipocyte gene expression by inhibiting the transcrip-tional regulatory functions of NF-kB
    • Ruan H, Pownall HJ, Lodish HF. 2003. Troglitazone antagonizes tumor necrosis factor-a-induced reprogramming of adipocyte gene expression by inhibiting the transcrip-tional regulatory functions of NF-kB. J Biol Chem 278: 28181-28192.
    • (2003) J Biol Chem , vol.278 , pp. 28181-28192
    • Ruan, H.1    Pownall, H.J.2    Lodish, H.F.3
  • 89
    • 84875215401 scopus 로고    scopus 로고
    • Safety, efficacy and convenience of colistimethate sodium dry powder for inhalation (Colobreathe DPI) in cystic fibrosis patients: A randomised study
    • for the Freedom Study Group
    • Schuster A, Haliburn C, Döring G, Goldman MH, for the Freedom Study Group. 2012. Safety, efficacy and convenience of colistimethate sodium dry powder for inhalation (Colobreathe DPI) in cystic fibrosis patients: A randomised study. Thorax 68: 344-350.
    • (2012) Thorax , vol.68 , pp. 344-350
    • Schuster, A.1    Haliburn, C.2    Döring, G.3    Goldman, M.H.4
  • 90
    • 39049142717 scopus 로고    scopus 로고
    • Exacerbations in cystic fibrosis: 3-Management
    • Smyth A, Elborn JS. 2008. Exacerbations in cystic fibrosis: 3-Management. Thorax 63: 180-184.
    • (2008) Thorax , vol.63 , pp. 180-184
    • Smyth, A.1    Elborn, J.S.2
  • 91
    • 84874139969 scopus 로고    scopus 로고
    • Prophylactic anti-staphylococ-cal antibiotics for cystic fibrosis
    • 23235585
    • Smyth AR, Walters S. 2012. Prophylactic anti-staphylococ-cal antibiotics for cystic fibrosis. Cochrane Database Syst Rev 12: CD001912. 23235585.
    • (2012) Cochrane Database Syst Rev , vol.12
    • Smyth, A.R.1    Walters, S.2
  • 92
    • 80053364019 scopus 로고    scopus 로고
    • Pulmonary exacerbations in cystic fibrosis
    • Stenbit AE, Flume PA. 2011. Pulmonary exacerbations in cystic fibrosis. Curr Opin Pulm Med 17: 442-447.
    • (2011) Curr Opin Pulm Med , vol.17 , pp. 442-447
    • Stenbit, A.E.1    Flume, P.A.2
  • 93
    • 84866061431 scopus 로고    scopus 로고
    • Early antibiotic treatment for Pseudo-monas aeruginosa eradication in patients with cystic fi-brosis: A randomised multicentre study comparing two different protocols
    • Taccetti G, Bianchini E, Cariani L, Buzzetti R, Costantini D, Trevisan F. 2012. Early antibiotic treatment for Pseudo-monas aeruginosa eradication in patients with cystic fi-brosis: A randomised multicentre study comparing two different protocols. Thorax 67: 853-859.
    • (2012) Thorax , vol.67 , pp. 853-859
    • Taccetti, G.1    Bianchini, E.2    Cariani, L.3    Buzzetti, R.4    Costantini, D.5    Trevisan, F.6
  • 97
    • 79959325084 scopus 로고    scopus 로고
    • Use of culture and molecular analysis to determine the effect of antibiotic treatment on microbial community diversity and abundance during exacerbation in patients with cystic fibrosis
    • Tunney MM, Klem ER, Fodor AA, Gilpin DF, Moriarty TF, McGrath SJ, Muhlebach MS, Boucher RC, Cardwell C, Doering G, et al. 2011. Use of culture and molecular analysis to determine the effect of antibiotic treatment on microbial community diversity and abundance during exacerbation in patients with cystic fibrosis. Thorax 66: 579-584.
    • (2011) Thorax , vol.66 , pp. 579-584
    • Tunney, M.M.1    Klem, E.R.2    Fodor, A.A.3    Gilpin, D.F.4    Moriarty, T.F.5    McGrath, S.J.6    Muhlebach, M.S.7    Boucher, R.C.8    Cardwell, C.9    Doering, G.10
  • 98
    • 0025868478 scopus 로고
    • Prevention of chronic Pseudomonas aeruginosa colonisation in cystic fibrosis by early treatment
    • Valerius NH, Koch C, Høiby N. 1991. Prevention of chronic Pseudomonas aeruginosa colonisation in cystic fibrosis by early treatment. Lancet 338: 725-726.
    • (1991) Lancet , vol.338 , pp. 725-726
    • Valerius, N.H.1    Koch, C.2    Høiby, N.3
  • 101
    • 77957296044 scopus 로고    scopus 로고
    • Assessing time to pulmonary function benefit following antibiotic treatment of acute cystic fibrosis exacerbations
    • VanDevanter DR, O'Riordan MA, Blumer JL, Konstan MW. 2010. Assessing time to pulmonary function benefit following antibiotic treatment of acute cystic fibrosis exacerbations. Respir Res 11: 137.
    • (2010) Respir Res , vol.11 , pp. 137
    • Vandevanter, D.R.1    O'Riordan, M.A.2    Blumer, J.L.3    Konstan, M.W.4
  • 102
    • 0034816784 scopus 로고    scopus 로고
    • Antioxidant imbalance in the lungs of cystic fibrosis transmembrane conductance regulator protein mutant mice
    • Velsor LW, van Heeckeren A, Day BJ. 2001. Antioxidant imbalance in the lungs of cystic fibrosis transmembrane conductance regulator protein mutant mice. Am J Physiol Lung Cell Mol Physiol 281: L31-L38.
    • (2001) Am J Physiol Lung Cell Mol Physiol , vol.281
    • Velsor, L.W.1    van Heeckeren, A.2    Day, B.J.3
  • 103
    • 84859839030 scopus 로고    scopus 로고
    • Basic science for the chest physician: Pseudomonas aeruginosa and the cystic fibrosis airway
    • Williams HD, Davies JC. 2012. Basic science for the chest physician: Pseudomonas aeruginosa and the cystic fibrosis airway. Thorax 67: 465-467.
    • (2012) Thorax , vol.67 , pp. 465-467
    • Williams, H.D.1    Davies, J.C.2
  • 104
    • 70350512309 scopus 로고    scopus 로고
    • Hydroxychloroquine-Pilot study of anti-inflammatory effects in cystic fibrosis
    • Williams B, Robinette M, Slovis B, Deretci V, Perkett E.2008. Hydroxychloroquine-Pilot study of anti-inflammatory effects in cystic fibrosis. Pediatr Pulmonol 43 (Suppl 31): 314.
    • (2008) Pediatr Pulmonol , vol.43 , Issue.SUPPL. 31 , pp. 314
    • Williams, B.1    Robinette, M.2    Slovis, B.3    Deretci, V.4    Perkett, E.5
  • 105
    • 0036445650 scopus 로고    scopus 로고
    • Modulation of inflammatory mediators and PPARg and NFkB expression by pravastatin in response to lipopro-teins in human monocytes in vitro
    • Zelvyte I, Dominaitiene R, Crisby M, Janciauskiene S. 2002. Modulation of inflammatory mediators and PPARg and NFkB expression by pravastatin in response to lipopro-teins in human monocytes in vitro. Pharmacol Res 45: 147-154.
    • (2002) Pharmacol Res , vol.45 , pp. 147-154
    • Zelvyte, I.1    Dominaitiene, R.2    Crisby, M.3    Janciauskiene, S.4
  • 107
    • 0346366979 scopus 로고    scopus 로고
    • 2 and ciglitazone, reduce systemic inflammation in polymicor-bial sepsis by modulation of signal transduction pathways
    • 12,14-prostaglandin J2 and ciglitazone, reduce systemic inflammation in polymicor-bial sepsis by modulation of signal transduction pathways. J Immunol 171: 6827-6837.
    • (2003) J Immunol , vol.171 , pp. 6827-6837
    • Zingarelli, B.1    Sheehan, M.2    Hake, P.W.3    O'Connor, M.4    Denen-Berg, A.5    Cook, J.A.6


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