Pulmonary oxidative stress response in young children with cystic fibrosis

Thorax

Volumn 52, Issue 6, 1997, Pages 557-560

  Hull, Jeremy ^a,c   Vervaart, Peter ^a   Grimwood, Keith ^b   Phelan, Peter ^a,b  

^a ROYAL CHILDREN'S HOSPITAL   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c JOHN RADCLIFFE HOSPITAL   (United Kingdom)

Author keywords

Cystic fibrosis; Infants; Pulmonary oxidative stress

Indexed keywords

ANTIOXIDANT ACTIVITY; ARTICLE; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; CYSTIC FIBROSIS; HUMAN; INFANT; LUNG INJURY; LUNG LAVAGE; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PRIORITY JOURNAL;

EID: 0030802906     PISSN: 00406376     EISSN: None     Source Type: Journal    
DOI: 10.1136/thx.52.6.557     Document Type: Article

References (13)

1. Portal BC, Richard M-J, Faure HS, Hadjian AJ, Favier AE. Altered antioxidant status and increased lipid peroxidation in children with cystic fibrosis. Am J Clin Nutr 1995;61: 843-7.
2. Brown RK, Kelly FJ. Evidence of increased oxidative damage in patients with cystic fibrosis. Pediatr Res 1994;36: 1-7.
3. Brown RK, Wyatt H, Price JF, Kelly FJ. Pulmonary dysfunction in cystic fibrosis is associated with oxidative stress. Eur Respir J 1996;9:334-9.
4. Von Ruecker AA, Bertele R, Harms HK. Calcium metabolism and cystic fibrosis: mitochondrial abnormalities suggest a modification of the mitochondrial membrane. Pediatr Res 1984;18:594-9.
5. Turrens JF, Boveris A. Generation of Superoxide anion by the NADH dehydrogenase of bovine heart mitochondria. Biochem J 1980;191:421-27.
6. Cantin AM, North SL, Hubbard RC, Crystal RG. Normal alveolar epithelial lining fluid contains high levels of glutathione. J Appl Physiol 1987;63:152-7.
7. Kugelman A, Choy HA, Ruiming L, MingShi M, Gozal E, Forman HJ. γ-Glutamyl transpeptidase is increased by oxidative stress in rat alveolar L2 epithelial cells. Am J Respir Cell Mol Biol 1994;11:586-92.
8. Roum JH, Buhl R, McElvaney NG, Borok Z, Crystal RG. Systemic deficiency of glutathione in cystic fibrosis. J Appl Physiol 1993;75:2419-24.
9. Armstrong DS, Grimwood K, Carlin JB, Olinsky A, Phelan PD. Bronchoalveolar lavage or oropharyngeal cultures to identify lower respiratory pathogens in infants with cystic fibrosis. Pediatr Pulmonol 1996;21:267-75.
10. Wolff SP. Ferrous ion oxidation in the presence of ferric ion xylene orange for measurement of hydroperoxides. Methods Enzymol 1994;105:182-9.
11. Meyer A, Buhl R, Kampf S, Magnussen H. Intravenous N-acetylcyteine and lung glutathione of patients with pulmonary fibrosis and normals. Am J Respir Crit Care Med 1995;152:1055-60.
12. Rennard SI, Bassett G, Lecossier D, O'Donnell KM, Pinkston P, Martin PG. Estimation of volume of epithelial lining fluid recovered by lavage using urea as a marker of dilution. J Appl Physiol 1986;60:532-8.
13. Joyce Brady M, Takahashi Y, Oakes SM, Rishi AR, Levine RA, Kinlough CL, et al. Synthesis and release of ampiphatic γ-glutamyl transferase by the pulmonary alveolar type 2 cell. J Biol Chem 1994;269:14219-26.