-
1
-
-
0031057517
-
Transcriptional activation by peroxisome proliferator-activated receptor γ is inhibited by phosphorylation at a consensus mitogen-activated protein kinase site
-
Adams M, Reginato MJ, Shao D, Lazar MA, Chatterjee VK. Transcriptional activation by peroxisome proliferator-activated receptor γ is inhibited by phosphorylation at a consensus mitogen-activated protein kinase site. J Biol Chem 272: 5128-5132, 1997.
-
(1997)
J Biol Chem
, vol.272
, pp. 5128-5132
-
-
Adams, M.1
Reginato, M.J.2
Shao, D.3
Lazar, M.A.4
Chatterjee, V.K.5
-
2
-
-
0036840478
-
Inflammatory response in airway epithelial cells isolated from patients with cystic fibrosis
-
Aldallal N, McNaughton EE, Manzel LJ, Richards AM, Zabner J, Ferkol TW, Look DC. Inflammatory response in airway epithelial cells isolated from patients with cystic fibrosis. Am J Respir Crit Care Med 166: 1248-1256, 2002.
-
(2002)
Am J Respir Crit Care Med
, vol.166
, pp. 1248-1256
-
-
Aldallal, N.1
McNaughton, E.E.2
Manzel, L.J.3
Richards, A.M.4
Zabner, J.5
Ferkol, T.W.6
Look, D.C.7
-
3
-
-
1642493927
-
Antiinflammatory roles of peroxisome proliferators-activated receptor gamma in human alveolar macrophages
-
Asada K, Sasaki S, Suda T, Chida K, Nakamura H. Antiinflammatory roles of peroxisome proliferators-activated receptor gamma in human alveolar macrophages. Am J Respir Crit Care Med 169: 195-200, 2004.
-
(2004)
Am J Respir Crit Care Med
, vol.169
, pp. 195-200
-
-
Asada, K.1
Sasaki, S.2
Suda, T.3
Chida, K.4
Nakamura, H.5
-
4
-
-
57049159466
-
-
AVMA. 2007 Report of the AVMA panel on euthanasia; http://www.avma.org/issues/animal_welfare/euthanasia.pdf.
-
AVMA. 2007 Report of the AVMA panel on euthanasia; http://www.avma.org/issues/animal_welfare/euthanasia.pdf.
-
-
-
-
5
-
-
0041887308
-
Peroxisome proliferator-activated receptors: Regulation of transcriptional activities and roles in inflammation
-
Blanquart C, Barbier O, Fruchart JC, Staels B, Glineur C. Peroxisome proliferator-activated receptors: regulation of transcriptional activities and roles in inflammation. J Steroid Biochem Mol Biol 85: 267-273, 2003.
-
(2003)
J Steroid Biochem Mol Biol
, vol.85
, pp. 267-273
-
-
Blanquart, C.1
Barbier, O.2
Fruchart, J.C.3
Staels, B.4
Glineur, C.5
-
6
-
-
0032135143
-
Overproduction of the CFTR R domain leads to increased levels of asioloGM1 and increased Pseudomonas aeruginosa binding by epithelial cells
-
Bryan R, Kube D, Perez A, Davis P, Prince A. Overproduction of the CFTR R domain leads to increased levels of asioloGM1 and increased Pseudomonas aeruginosa binding by epithelial cells. Am J Respir Cell Mol Biol 19: 269-277, 1998.
-
(1998)
Am J Respir Cell Mol Biol
, vol.19
, pp. 269-277
-
-
Bryan, R.1
Kube, D.2
Perez, A.3
Davis, P.4
Prince, A.5
-
7
-
-
34547589477
-
Modulation of PPAR activity via phosphorylation
-
Burns KA, Vanden Heuvel JP. Modulation of PPAR activity via phosphorylation. Biochim Biophys Acta 1771: 952-960, 2007.
-
(2007)
Biochim Biophys Acta
, vol.1771
, pp. 952-960
-
-
Burns, K.A.1
Vanden Heuvel, J.P.2
-
8
-
-
0037090469
-
Prolonged inflammatory response to acute Pseudomonas challenge in interleukin-10 knockout mice
-
Chmiel JF, Konstan MW, Saadane A, Krenicky JE, Lester Kirchner H, Berger M. Prolonged inflammatory response to acute Pseudomonas challenge in interleukin-10 knockout mice. Am J Respir Crit Care Med 165: 1176-1181, 2002.
-
(2002)
Am J Respir Crit Care Med
, vol.165
, pp. 1176-1181
-
-
Chmiel, J.F.1
Konstan, M.W.2
Saadane, A.3
Krenicky, J.E.4
Lester Kirchner, H.5
Berger, M.6
-
9
-
-
0032081281
-
Activation of NF-κB by adherent Pseudomonas aeruginosa in normal and cystic fibrosis respiratory epithelial cells
-
DiMango E, Ratner AJ, Bryan R, Tabibi S, Prince A. Activation of NF-κB by adherent Pseudomonas aeruginosa in normal and cystic fibrosis respiratory epithelial cells. J Clin Invest 101: 2598-2606, 1998.
-
(1998)
J Clin Invest
, vol.101
, pp. 2598-2606
-
-
DiMango, E.1
Ratner, A.J.2
Bryan, R.3
Tabibi, S.4
Prince, A.5
-
10
-
-
0037040272
-
Interferon-γ-mediated activation and ubiquitin-proteasome-dependent degradation of PPARγ in adipocytes
-
Floyd ZE, Stephen JM. Interferon-γ-mediated activation and ubiquitin-proteasome-dependent degradation of PPARγ in adipocytes. J Biol Chem 277: 4062-4068, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 4062-4068
-
-
Floyd, Z.E.1
Stephen, J.M.2
-
11
-
-
0036085182
-
Characterization of LPS-induced lung inflammation in cftr-/- mice and the effect of docosahexaenoic acid
-
Freedman SD, Weinstein D, Blanco PG, Martinez-Clark P, Urman S, Zaman M, Morrow JD, Alvarez JG. Characterization of LPS-induced lung inflammation in cftr-/- mice and the effect of docosahexaenoic acid. J Appl Physiol 92: 2169-2176, 2002.
-
(2002)
J Appl Physiol
, vol.92
, pp. 2169-2176
-
-
Freedman, S.D.1
Weinstein, D.2
Blanco, P.G.3
Martinez-Clark, P.4
Urman, S.5
Zaman, M.6
Morrow, J.D.7
Alvarez, J.G.8
-
12
-
-
34447522038
-
Matrix metalloprotease-9 dysregulation in lower airway secretions of cystic fibrosis patients
-
Gaggar A, Li Y, Weathington N, Winkler M, Kong M, Jackson P, Blalock JE, Clancy JP. Matrix metalloprotease-9 dysregulation in lower airway secretions of cystic fibrosis patients. Am J Physiol Lung Cell Mol Physiol 293: L96-L104, 2007.
-
(2007)
Am J Physiol Lung Cell Mol Physiol
, vol.293
-
-
Gaggar, A.1
Li, Y.2
Weathington, N.3
Winkler, M.4
Kong, M.5
Jackson, P.6
Blalock, J.E.7
Clancy, J.P.8
-
13
-
-
1542574200
-
Activation of peroxisome proliferators- activated receptor-gamma in dendritic cells inhibits the development of eosinophilic airway inflammation in a mouse model of asthma
-
Hammad H, de heer HJ, Soullié T, Angeli V, Trottein F, Hooqsteden HC, Lambrecht BN. Activation of peroxisome proliferators- activated receptor-gamma in dendritic cells inhibits the development of eosinophilic airway inflammation in a mouse model of asthma. Am J Pathol 164: 263-271, 2004.
-
(2004)
Am J Pathol
, vol.164
, pp. 263-271
-
-
Hammad, H.1
de heer, H.J.2
Soullié, T.3
Angeli, V.4
Trottein, F.5
Hooqsteden, H.C.6
Lambrecht, B.N.7
-
14
-
-
14944344881
-
NF-κB activation and sustained IL-8 gene expression in primary cultures of cystic fibrosis airway epithelial cells stimulated with Pseudomonas aeruginosa
-
Joseph T, Look D, Ferkol T. NF-κB activation and sustained IL-8 gene expression in primary cultures of cystic fibrosis airway epithelial cells stimulated with Pseudomonas aeruginosa. Am J Physiol Lung Cell Mol Physiol 288: L417-L479, 2005.
-
(2005)
Am J Physiol Lung Cell Mol Physiol
, vol.288
-
-
Joseph, T.1
Look, D.2
Ferkol, T.3
-
15
-
-
0036367311
-
An in vitro model of differentiated human airway epithelia. Methods for establishing primary cultures
-
Karp PH, Moninger TO, Weber SP, Nesselhauf TS, Launspach JL, Zabner J, Welsh MJ. An in vitro model of differentiated human airway epithelia. Methods for establishing primary cultures. Methods Mol Biol 188: 15-37, 2002.
-
(2002)
Methods Mol Biol
, vol.188
, pp. 15-37
-
-
Karp, P.H.1
Moninger, T.O.2
Weber, S.P.3
Nesselhauf, T.S.4
Launspach, J.L.5
Zabner, J.6
Welsh, M.J.7
-
16
-
-
0025081636
-
Culture of human tracheal epithelial cells for studies of cAMP metabolism
-
Kercsmar CM, Silski C, Infeld M, Davis PB. Culture of human tracheal epithelial cells for studies of cAMP metabolism. Am J Respir Cell Mol Biol 2: 33-39, 1990.
-
(1990)
Am J Respir Cell Mol Biol
, vol.2
, pp. 33-39
-
-
Kercsmar, C.M.1
Silski, C.2
Infeld, M.3
Davis, P.B.4
-
17
-
-
0028914085
-
Early pulmonary inflammation in infants with cystic fibrosis
-
Khan TZ, Wagener JS, Bost T, Martinez J, Accurso FJ, Riches DW. Early pulmonary inflammation in infants with cystic fibrosis. Am J Respir Crit Care Med 151: 1075-1082, 1995.
-
(1995)
Am J Respir Crit Care Med
, vol.151
, pp. 1075-1082
-
-
Khan, T.Z.1
Wagener, J.S.2
Bost, T.3
Martinez, J.4
Accurso, F.J.5
Riches, D.W.6
-
18
-
-
0028914667
-
Effect of high-dose ibuprofen in patients with cystic fibrosis
-
Konstan MW, Byard PJ, Hoppel CL, Davis PB. Effect of high-dose ibuprofen in patients with cystic fibrosis. N Engl J Med 332: 848-854, 1995.
-
(1995)
N Engl J Med
, vol.332
, pp. 848-854
-
-
Konstan, M.W.1
Byard, P.J.2
Hoppel, C.L.3
Davis, P.B.4
-
19
-
-
0345358534
-
Statin-mediated correction of STAT1 signaling and inducible nitric oxide synthase expression in cystic fibrosis epithelial cells
-
Kreiselmeier NE, Kraynack NC, Corey DA, Kelley TJ. Statin-mediated correction of STAT1 signaling and inducible nitric oxide synthase expression in cystic fibrosis epithelial cells. Am J Physiol Lung Cell Mol Physiol 285: L1286-L1295, 2003.
-
(2003)
Am J Physiol Lung Cell Mol Physiol
, vol.285
-
-
Kreiselmeier, N.E.1
Kraynack, N.C.2
Corey, D.A.3
Kelley, T.J.4
-
20
-
-
0035006957
-
Terminal sialylation is altered in airway cells with impaired CFTR-mediated chloride transport
-
Kube D, Adams L, Perez A, Davis PB. Terminal sialylation is altered in airway cells with impaired CFTR-mediated chloride transport. Am J Physiol Lung Cell Mol Physiol 280: L482-L492, 2001.
-
(2001)
Am J Physiol Lung Cell Mol Physiol
, vol.280
-
-
Kube, D.1
Adams, L.2
Perez, A.3
Davis, P.B.4
-
21
-
-
0034997191
-
Proinflammatory cytokine responses to P. aeruginosa infection in human airway epithelial cell lines
-
Kube D, Sontich U, Fletcher D, Davis PB. Proinflammatory cytokine responses to P. aeruginosa infection in human airway epithelial cell lines. Am J Physiol Lung Cell Mol Physiol 280: L493-L502, 2001.
-
(2001)
Am J Physiol Lung Cell Mol Physiol
, vol.280
-
-
Kube, D.1
Sontich, U.2
Fletcher, D.3
Davis, P.B.4
-
22
-
-
33745451812
-
Peroxisome proliferator activated receptor-gamma modulates reactive oxygen species generation and activation of nuclear factor-kappaB and hypoxia-inducible factor 1 alpha in allergic airway disease of mice
-
Lee KS, Kim SR, Park SJ, Park HS, Min KH, Jin SM, Lee MK, Kim UH, Lee YC. Peroxisome proliferator activated receptor-gamma modulates reactive oxygen species generation and activation of nuclear factor-kappaB and hypoxia-inducible factor 1 alpha in allergic airway disease of mice. J Allergy Clin Immunol 118: 120-127, 2006.
-
(2006)
J Allergy Clin Immunol
, vol.118
, pp. 120-127
-
-
Lee, K.S.1
Kim, S.R.2
Park, S.J.3
Park, H.S.4
Min, K.H.5
Jin, S.M.6
Lee, M.K.7
Kim, U.H.8
Lee, Y.C.9
-
23
-
-
0034822263
-
G551D CF mice display an abnormal host response and have impaired clearance of Pseudomonas lung disease
-
McMorran BJ, Palmer JS, Lunn DP, Oceandy D, Costelloe EO, Thomas GR, Hume DA, Wainwright BJ. G551D CF mice display an abnormal host response and have impaired clearance of Pseudomonas lung disease. Am J Physiol Lung Cell Mol Physiol 281: L740-L747, 2001.
-
(2001)
Am J Physiol Lung Cell Mol Physiol
, vol.281
-
-
McMorran, B.J.1
Palmer, J.S.2
Lunn, D.P.3
Oceandy, D.4
Costelloe, E.O.5
Thomas, G.R.6
Hume, D.A.7
Wainwright, B.J.8
-
24
-
-
0032770489
-
Quantification of inflammatory responses to bacteria in young cystic fibrosis and control patients
-
Muhlebach MS, Stewart PW, Leigh MW, Noah TL. Quantification of inflammatory responses to bacteria in young cystic fibrosis and control patients. Am J Respir Crit Care Med 160: 186-191, 1999.
-
(1999)
Am J Respir Crit Care Med
, vol.160
, pp. 186-191
-
-
Muhlebach, M.S.1
Stewart, P.W.2
Leigh, M.W.3
Noah, T.L.4
-
25
-
-
2442581515
-
Quantitative cytokine gene expression in CF airway
-
Muhlebach MS, Reed W, Noah TL. Quantitative cytokine gene expression in CF airway. Pediatr Pulmonol 37: 393-399, 2004.
-
(2004)
Pediatr Pulmonol
, vol.37
, pp. 393-399
-
-
Muhlebach, M.S.1
Reed, W.2
Noah, T.L.3
-
26
-
-
0031035884
-
Nasal and bronchoalveolar lavage fluid cytokines in early cystic fibrosis
-
Noah TL, Black HR, Chenq PW, Wood RE, Leigh MW. Nasal and bronchoalveolar lavage fluid cytokines in early cystic fibrosis. J Infect Dis 175: 638-647, 1997.
-
(1997)
J Infect Dis
, vol.175
, pp. 638-647
-
-
Noah, T.L.1
Black, H.R.2
Chenq, P.W.3
Wood, R.E.4
Leigh, M.W.5
-
27
-
-
3042856185
-
Decreased expression of peroxisome proliferator activated receptor gamma in cftr-/- mice
-
Ollero M, Junaidi O, Zaman MM, Tzameli I, Ferrando AA, Andersson C, Blanco PG, Bialecki E, Freedman SD. Decreased expression of peroxisome proliferator activated receptor gamma in cftr-/- mice. J Cell Physiol 200: 235-244, 2004.
-
(2004)
J Cell Physiol
, vol.200
, pp. 235-244
-
-
Ollero, M.1
Junaidi, O.2
Zaman, M.M.3
Tzameli, I.4
Ferrando, A.A.5
Andersson, C.6
Blanco, P.G.7
Bialecki, E.8
Freedman, S.D.9
-
28
-
-
0037373271
-
Activation of peroxisome proliferator-activated receptors in human airway smooth muscle cells has a superior anti-inflammatory profile to corticosteroids: Relevance for chronic obstructive pulmonary disease therapy
-
Patel HJ, Belvisi MG, Bishop-Bailey D, Yacoub MH, Mitchell JA. Activation of peroxisome proliferator-activated receptors in human airway smooth muscle cells has a superior anti-inflammatory profile to corticosteroids: relevance for chronic obstructive pulmonary disease therapy. J Immunol 170: 2663-2669, 2003.
-
(2003)
J Immunol
, vol.170
, pp. 2663-2669
-
-
Patel, H.J.1
Belvisi, M.G.2
Bishop-Bailey, D.3
Yacoub, M.H.4
Mitchell, J.A.5
-
29
-
-
3543150782
-
Gene profile after Pseudomonas aeruginosa exposure in cystic fibrosis tracheal epithelial cells vs. normal tracheal cells
-
Perez A, Davis PB. Gene profile after Pseudomonas aeruginosa exposure in cystic fibrosis tracheal epithelial cells vs. normal tracheal cells. JSFG 5: 179-194, 2004.
-
(2004)
JSFG
, vol.5
, pp. 179-194
-
-
Perez, A.1
Davis, P.B.2
-
30
-
-
33847025695
-
CFTR inhibition mimics the cystic fibrosis inflammatory profile
-
Perez A, Issler AC, Cotton CU, Kelley TJ, Verkman AS, Davis PB. CFTR inhibition mimics the cystic fibrosis inflammatory profile. Am J Physiol Lung Cell Mol Physiol 292: L383-L395, 2007.
-
(2007)
Am J Physiol Lung Cell Mol Physiol
, vol.292
-
-
Perez, A.1
Issler, A.C.2
Cotton, C.U.3
Kelley, T.J.4
Verkman, A.S.5
Davis, P.B.6
-
31
-
-
0033823601
-
Pseudomonas aeruginosa induction of apoptosis in respiratory epithelial cells: Analysis of the effects of cystic fibrosis transmembrane conductance regulator dysfunction and bacterial virulence factors
-
Rajan S, Cacalano G, Bryan R, Ratner AJ, Sontich CU, van Heeckeren A, Davis PB, Prince A. Pseudomonas aeruginosa induction of apoptosis in respiratory epithelial cells: analysis of the effects of cystic fibrosis transmembrane conductance regulator dysfunction and bacterial virulence factors. Am J Respir Cell Mol Biol 23: 304-312, 2000.
-
(2000)
Am J Respir Cell Mol Biol
, vol.23
, pp. 304-312
-
-
Rajan, S.1
Cacalano, G.2
Bryan, R.3
Ratner, A.J.4
Sontich, C.U.5
van Heeckeren, A.6
Davis, P.B.7
Prince, A.8
-
32
-
-
0037399647
-
Nuclear receptors: Integration of multiple signaling pathways through phosphorylation
-
Rochette-Egly C. Nuclear receptors: integration of multiple signaling pathways through phosphorylation. Cell Signal 15: 355-366, 2003.
-
(2003)
Cell Signal
, vol.15
, pp. 355-366
-
-
Rochette-Egly, C.1
-
33
-
-
33646143775
-
Acute Pseudomonas challenge in cystic fibrosis mice causes prolonged nuclear factor-kappaB activation, cytokine secretion, and persistent lung inflammation
-
Saadne A, Soltys J, Berger M. Acute Pseudomonas challenge in cystic fibrosis mice causes prolonged nuclear factor-kappaB activation, cytokine secretion, and persistent lung inflammation. J Allergy Clin Immunol 117: 1163-1169, 2006.
-
(2006)
J Allergy Clin Immunol
, vol.117
, pp. 1163-1169
-
-
Saadne, A.1
Soltys, J.2
Berger, M.3
-
34
-
-
16244368754
-
Induced sputum matrix metalloproteinase-9 correlates with lung function and airway inflammation in children with cystic fibrosis
-
Sagel SD, Kapsner RK, Osberg I. Induced sputum matrix metalloproteinase-9 correlates with lung function and airway inflammation in children with cystic fibrosis. Pediatr Pulmonol 39: 224-232, 2005.
-
(2005)
Pediatr Pulmonol
, vol.39
, pp. 224-232
-
-
Sagel, S.D.1
Kapsner, R.K.2
Osberg, I.3
-
35
-
-
0035888715
-
Airway inflammation in children with cystic fibrosis and healthy children assessed by sputum induction
-
Sagel SD, Kapsner R, Osberq I, Sontaq MK, Accurso FJ. Airway inflammation in children with cystic fibrosis and healthy children assessed by sputum induction. Am J Respir Crit Care Med 164: 1425-1431, 2001.
-
(2001)
Am J Respir Crit Care Med
, vol.164
, pp. 1425-1431
-
-
Sagel, S.D.1
Kapsner, R.2
Osberq, I.3
Sontaq, M.K.4
Accurso, F.J.5
-
36
-
-
0032569902
-
Interdomain communication regulating ligand binding by PPARγ
-
Shao D, Rangwala SM, Bailey ST, Krakow SL, Reginato MJ, Lazar MA. Interdomain communication regulating ligand binding by PPARγ. Nature 396: 377-380, 1998.
-
(1998)
Nature
, vol.396
, pp. 377-380
-
-
Shao, D.1
Rangwala, S.M.2
Bailey, S.T.3
Krakow, S.L.4
Reginato, M.J.5
Lazar, M.A.6
-
37
-
-
0031452350
-
Excessive inflammatory response of cystic fibrosis mice to bronchopulmonary infection with Pseudomonas
-
van Heeckeren A, Walenga R, Konstan MW, Bonfield T, Davis PB, Ferkol T. Excessive inflammatory response of cystic fibrosis mice to bronchopulmonary infection with Pseudomonas. J Clin Invest 100: 2810-2815, 1997.
-
(1997)
J Clin Invest
, vol.100
, pp. 2810-2815
-
-
van Heeckeren, A.1
Walenga, R.2
Konstan, M.W.3
Bonfield, T.4
Davis, P.B.5
Ferkol, T.6
-
39
-
-
32144455216
-
Response to acute lung infection with mucoid Pseudomonas aeruginosa in cystic fibrosis mice
-
van Heeckeren AM, Schluchter MD, Xue W, Davis PB. Response to acute lung infection with mucoid Pseudomonas aeruginosa in cystic fibrosis mice. Am J Respir Crit Care Med 173: 288-296, 2006.
-
(2006)
Am J Respir Crit Care Med
, vol.173
, pp. 288-296
-
-
van Heeckeren, A.M.1
Schluchter, M.D.2
Xue, W.3
Davis, P.B.4
-
40
-
-
0033831270
-
Exaggerated activation of nuclear factor-κB and altered IκB-β processing in cystic fibrosis bronchial epithelial cells
-
Venkatakrishnan A, Stecenko AA, King G, Blackwell TR, Brigham KL, Christman JW, Blackwell TS. Exaggerated activation of nuclear factor-κB and altered IκB-β processing in cystic fibrosis bronchial epithelial cells. Am J Respir Cell Mol Biol 23: 396-403, 2000.
-
(2000)
Am J Respir Cell Mol Biol
, vol.23
, pp. 396-403
-
-
Venkatakrishnan, A.1
Stecenko, A.A.2
King, G.3
Blackwell, T.R.4
Brigham, K.L.5
Christman, J.W.6
Blackwell, T.S.7
|