Implementation challenges for designing Integrated In Vitro Testing Strategies (ITS) aiming at reducing and replacing animal experimentation

Toxicology in Vitro

Volumn 26, Issue 3, 2012, Pages 526-534

  De Wever, Bart ^a,b   Fuchs, Horst W ^c   Gaca, Marianna ^d   Krul, Cyrille ^e   Mikulowski, Stan ^f   Poth, Albrecht ^g   Roggen, Erwin L ^h   Vilà, Maya R ⁱ  

^a HENKEL KGAA   (Germany)

^b ALTEXA Development   (Monaco)

^c Biotechnologie Vertrieb GmbH   (Germany)

^d BRITISH AMERICAN TOBACCO   (United Kingdom)

^e TNO   (Netherlands)

^f Biovator AB   (Sweden)

^g Harlan   (Switzerland)

^h NOVOZYMES A S   (Denmark)

ⁱ LEITAT TECHNOLOGICAL CENTER   (Spain)

Author keywords

Eye irritation; ITS; ITS design; IVTIP; Replacement; Reproductive toxicity; Testing strategies; Validation

Indexed keywords

ANIMAL TESTING REDUCTION; ANIMAL TESTING REPLACEMENT; ARTICLE; BIOSAFETY; CHEMICAL INDUSTRY; DATA COLLECTION METHOD; DECISION MAKING; DRUG INDUSTRY; EXPERIMENTAL STUDY; EYE IRRITATION; HUMAN; IN VITRO STUDY; INFORMATION DISSEMINATION; LEGAL PROCEDURE; NONHUMAN; PREDICTION; PROCESS DESIGN; REPRODUCTIVE TOXICITY; RISK ASSESSMENT; STRATEGIC PLANNING; TOXICITY TESTING; VALIDATION PROCESS;

ANIMAL TESTING ALTERNATIVES; ANIMALS; CHEMICAL INDUSTRY; DRUG INDUSTRY; HUMANS; MODELS, BIOLOGICAL; RISK ASSESSMENT; TOXICITY TESTS; TOXICOLOGY;

ANIMALIA;

EID: 84857686257     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2012.01.009     Document Type: Article

References (9)

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