-
1
-
-
79551477688
-
Reduction of radiation-induced vascular nitrosative stress by the vitamin E analog γ-tocotrienol: evidence of a role for tetrahydrobiopterin
-
Berbee M., Fu Q., Boerma M., Pathak R., Zhou D., Sreekumar K., Hauer-Jensen M. Reduction of radiation-induced vascular nitrosative stress by the vitamin E analog γ-tocotrienol: evidence of a role for tetrahydrobiopterin. Int. J. Radiat. Oncol. Biol. Phys. 2011, 79:884-891.
-
(2011)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.79
, pp. 884-891
-
-
Berbee, M.1
Fu, Q.2
Boerma, M.3
Pathak, R.4
Zhou, D.5
Sreekumar, K.6
Hauer-Jensen, M.7
-
2
-
-
84861134293
-
Identification of novel components of NAD-utilizing metabolic pathways and prediction of their biochemical functions
-
Desouza R.F., Aravind L. Identification of novel components of NAD-utilizing metabolic pathways and prediction of their biochemical functions. Mol. Biosyst. 2012, 8:1661-1677.
-
(2012)
Mol. Biosyst.
, vol.8
, pp. 1661-1677
-
-
Desouza, R.F.1
Aravind, L.2
-
3
-
-
0025230367
-
Trends and developments in radioprotection: the effect of nicotinamide on DNA repair
-
Riklis E., Kol R., Marko R. Trends and developments in radioprotection: the effect of nicotinamide on DNA repair. Int. J. Radiat. Biol. 1990, 57:699-708.
-
(1990)
Int. J. Radiat. Biol.
, vol.57
, pp. 699-708
-
-
Riklis, E.1
Kol, R.2
Marko, R.3
-
4
-
-
0027105871
-
Radioprotection of DNA by biochemical mechanisms
-
Riklis E. Radioprotection of DNA by biochemical mechanisms. Adv. Space Res. 1992, 12:209-212.
-
(1992)
Adv. Space Res.
, vol.12
, pp. 209-212
-
-
Riklis, E.1
-
5
-
-
20644452457
-
Ionizing radiations in Caenorhabditis elegans induce poly(ADP-ribosyl)ation, a conserved DNA-damage response essential for survival
-
Dequen F., Gagnon S.N., Desnoyers S. Ionizing radiations in Caenorhabditis elegans induce poly(ADP-ribosyl)ation, a conserved DNA-damage response essential for survival. DNA Repair 2005, 4:814-825.
-
(2005)
DNA Repair
, vol.4
, pp. 814-825
-
-
Dequen, F.1
Gagnon, S.N.2
Desnoyers, S.3
-
7
-
-
79952751250
-
Overcoming temozolomide resistance in glioblastoma via dual inhibition of NAD+ biosynthesis and base excision repair
-
Goellner E.M., Grimme B., Brown A.R., Lin Y.C., Wang X.H., Sugrue K.F., Mitchell L., Trivedi R.N., Tang J.B., Sobol R.W. Overcoming temozolomide resistance in glioblastoma via dual inhibition of NAD+ biosynthesis and base excision repair. Cancer Res. 2011, 71:2308-2317.
-
(2011)
Cancer Res.
, vol.71
, pp. 2308-2317
-
-
Goellner, E.M.1
Grimme, B.2
Brown, A.R.3
Lin, Y.C.4
Wang, X.H.5
Sugrue, K.F.6
Mitchell, L.7
Trivedi, R.N.8
Tang, J.B.9
Sobol, R.W.10
-
8
-
-
42049105745
-
Nicotinamide adenine dinucleotide based therapeutics
-
Chen L., Petrelli R., Felczak K., Gao G., Bonnac L., Yu J.S., Bennett E.M., Pankiewicz K.W. Nicotinamide adenine dinucleotide based therapeutics. Curr. Med. Chem. 2008, 15:650-670.
-
(2008)
Curr. Med. Chem.
, vol.15
, pp. 650-670
-
-
Chen, L.1
Petrelli, R.2
Felczak, K.3
Gao, G.4
Bonnac, L.5
Yu, J.S.6
Bennett, E.M.7
Pankiewicz, K.W.8
-
9
-
-
75149149167
-
Bioenergetic metabolites regulate base excision repair-dependent cell death in response to DNA damage
-
Tang J.B., Goellner E.M., Wang X.H., Trivedi R.N., Croix C.M., Jelezcova E., Svilar D., Brown A.R., Sobol R.W. Bioenergetic metabolites regulate base excision repair-dependent cell death in response to DNA damage. Mol. Cancer Res. 2010, 8:67-79.
-
(2010)
Mol. Cancer Res.
, vol.8
, pp. 67-79
-
-
Tang, J.B.1
Goellner, E.M.2
Wang, X.H.3
Trivedi, R.N.4
Croix, C.M.5
Jelezcova, E.6
Svilar, D.7
Brown, A.R.8
Sobol, R.W.9
-
10
-
-
84861702357
-
Radiosensitization effect of poly(ADP-ribose) polymerase inhibition in cells exposed to low and high liner energy transfer radiation
-
Hirai T., Shirai H., Fujimori H., Okayasu R., Sasai K., Masutani M. Radiosensitization effect of poly(ADP-ribose) polymerase inhibition in cells exposed to low and high liner energy transfer radiation. Cancer Sci. 2012, 103:1045-1050.
-
(2012)
Cancer Sci.
, vol.103
, pp. 1045-1050
-
-
Hirai, T.1
Shirai, H.2
Fujimori, H.3
Okayasu, R.4
Sasai, K.5
Masutani, M.6
-
11
-
-
84860135976
-
Conformational transitions of proteins engaged in DNA double-strand break repair, analysed by tryptophan fluorescence emission and FRET
-
Stankova K., Ivanova K., Mladenov E., Rosidi B., Sharma A., Boteva R., Iliakis G. Conformational transitions of proteins engaged in DNA double-strand break repair, analysed by tryptophan fluorescence emission and FRET. Biochem. J. 2012, 443:701-709.
-
(2012)
Biochem. J.
, vol.443
, pp. 701-709
-
-
Stankova, K.1
Ivanova, K.2
Mladenov, E.3
Rosidi, B.4
Sharma, A.5
Boteva, R.6
Iliakis, G.7
-
12
-
-
0025733383
-
DNA strand breaks and DNA repair response in lymphocytes after chronic in vivo exposure to very low doses of ionizing radiation in mice
-
James S.J., Enger S.M., Makinodan T. DNA strand breaks and DNA repair response in lymphocytes after chronic in vivo exposure to very low doses of ionizing radiation in mice. Mutat. Res. Fundam. Mol. Mech. Mutagen. 1991, 249:255-263.
-
(1991)
Mutat. Res. Fundam. Mol. Mech. Mutagen.
, vol.249
, pp. 255-263
-
-
James, S.J.1
Enger, S.M.2
Makinodan, T.3
-
14
-
-
79957557182
-
Dissecting systemic control of metabolism and aging in the NAD World: The importance of SIRT1 and NAMPT-mediated NAD biosynthesis
-
Imai S. Dissecting systemic control of metabolism and aging in the NAD World: The importance of SIRT1 and NAMPT-mediated NAD biosynthesis. FEBS Lett. 2011, 585:1657-1662.
-
(2011)
FEBS Lett.
, vol.585
, pp. 1657-1662
-
-
Imai, S.1
-
15
-
-
77956487620
-
Poly(ADP-Ribose) polymerase inhibition as a model for synthetic lethality in developing radiation oncology targets
-
Chalmers A.J., Lakshman M., Chan N., Bristow R.G. Poly(ADP-Ribose) polymerase inhibition as a model for synthetic lethality in developing radiation oncology targets. Semin. Radiat. Oncol. 2010, 20:274-281.
-
(2010)
Semin. Radiat. Oncol.
, vol.20
, pp. 274-281
-
-
Chalmers, A.J.1
Lakshman, M.2
Chan, N.3
Bristow, R.G.4
-
16
-
-
84885391103
-
Mechanism of radiosensitization by inhibitors of poly (ADP-Ribose) polymerase (PARP)
-
Glazer P.M. Mechanism of radiosensitization by inhibitors of poly (ADP-Ribose) polymerase (PARP). Int. J. Radiat. Oncol. Biol. Phys. 2010, 78:S87-S88.
-
(2010)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.78
-
-
Glazer, P.M.1
-
17
-
-
84861231399
-
The diverse roles and clinical relevance of PARPs in DNA damage repair: current state of the art
-
Vos M.D., Schreiber V., Dantzer F. The diverse roles and clinical relevance of PARPs in DNA damage repair: current state of the art. Biochem. Pharmacol. 2012, 84:137-146.
-
(2012)
Biochem. Pharmacol.
, vol.84
, pp. 137-146
-
-
Vos, M.D.1
Schreiber, V.2
Dantzer, F.3
-
18
-
-
79952008439
-
The DNA-binding domain of human PARP-1 interacts with DNA single-strand breaks as a monomer through its second zinc finger
-
Eustermann S., Videler H., Yang J., Cole P.T., Gruszka D., Veprintsev D., Neuhaus D. The DNA-binding domain of human PARP-1 interacts with DNA single-strand breaks as a monomer through its second zinc finger. J. Mol. Biol. 2011, 407:149-170.
-
(2011)
J. Mol. Biol.
, vol.407
, pp. 149-170
-
-
Eustermann, S.1
Videler, H.2
Yang, J.3
Cole, P.T.4
Gruszka, D.5
Veprintsev, D.6
Neuhaus, D.7
-
19
-
-
37149051869
-
Changes in poly(ADP-ribose) level modulate the kinetics of DNA strand break rejoining
-
Ryabokon N.I., Goncharova R.I., Duburs G., Hancock R., Rzeszowska-Wolny J. Changes in poly(ADP-ribose) level modulate the kinetics of DNA strand break rejoining. Mutat. Res. Fundam. Mol. Mech. Mutagen. 2008, 637:173-181.
-
(2008)
Mutat. Res. Fundam. Mol. Mech. Mutagen.
, vol.637
, pp. 173-181
-
-
Ryabokon, N.I.1
Goncharova, R.I.2
Duburs, G.3
Hancock, R.4
Rzeszowska-Wolny, J.5
-
20
-
-
0035281786
-
The world according to PARP
-
Smith S. The world according to PARP. Trends Biochem. Sci. 2001, 26:174-179.
-
(2001)
Trends Biochem. Sci.
, vol.26
, pp. 174-179
-
-
Smith, S.1
-
21
-
-
0030938581
-
Poly(ADP-ribose) polymerase enhances activator-dependent transcription in vitro
-
Meisterernst M., Stelzer G., Roeder R.G. Poly(ADP-ribose) polymerase enhances activator-dependent transcription in vitro. Proc. Natl. Acad. Sci. 1997, 94:2261-2265.
-
(1997)
Proc. Natl. Acad. Sci.
, vol.94
, pp. 2261-2265
-
-
Meisterernst, M.1
Stelzer, G.2
Roeder, R.G.3
-
22
-
-
67649888368
-
Molecular mechanism of poly(ADP-ribosyl)ation by PARP1 and identification of lysine residues as ADP-ribose acceptor sites
-
Altmeyer M., Paul S., Hassa O., Fey M., Hottiger M.O. Molecular mechanism of poly(ADP-ribosyl)ation by PARP1 and identification of lysine residues as ADP-ribose acceptor sites. Nucleic Acids Res. 2009, 37:3723-3738.
-
(2009)
Nucleic Acids Res.
, vol.37
, pp. 3723-3738
-
-
Altmeyer, M.1
Paul, S.2
Hassa, O.3
Fey, M.4
Hottiger, M.O.5
-
23
-
-
33749260519
-
Nuclear ADP-ribosylation reactions in mammalian cells: where are we today and where are we going?
-
Hassa P.O., Haenni S.S., Elser M., Hottiger M.O. Nuclear ADP-ribosylation reactions in mammalian cells: where are we today and where are we going?. Microbiol. Mol. Biol. Rev. 2006, 70:789-829.
-
(2006)
Microbiol. Mol. Biol. Rev.
, vol.70
, pp. 789-829
-
-
Hassa, P.O.1
Haenni, S.S.2
Elser, M.3
Hottiger, M.O.4
-
25
-
-
79960206370
-
PARG is recruited to DNA damage sites through poly(ADP-ribose)- and PCNA-dependent mechanisms
-
Mortusewicz O., Fouquerel E., Amé J.C., Leonhardt H., Schreiber V. PARG is recruited to DNA damage sites through poly(ADP-ribose)- and PCNA-dependent mechanisms. Nucleic Acids Res. 2011, 39:5045-5056.
-
(2011)
Nucleic Acids Res.
, vol.39
, pp. 5045-5056
-
-
Mortusewicz, O.1
Fouquerel, E.2
Amé, J.C.3
Leonhardt, H.4
Schreiber, V.5
-
26
-
-
34547783237
-
Spatial and functional relationship between poly(ADP-ribose) polymerase-1 and poly(ADP-ribose) glycohydrolase in the brain
-
Poitras M.F., Koh D.W., Yu S.W., Andrabi S.A., Mandir A.S., Poirier G.G., Dawson V.L., Dawson T.M. Spatial and functional relationship between poly(ADP-ribose) polymerase-1 and poly(ADP-ribose) glycohydrolase in the brain. Neuroscience 2007, 148:198-211.
-
(2007)
Neuroscience
, vol.148
, pp. 198-211
-
-
Poitras, M.F.1
Koh, D.W.2
Yu, S.W.3
Andrabi, S.A.4
Mandir, A.S.5
Poirier, G.G.6
Dawson, V.L.7
Dawson, T.M.8
-
27
-
-
77958108544
-
Factors affecting the yields of C1' and C5' oxidation products in radiation-damaged DNA: the indirect effect
-
Price C.S., Razskazovskiy Y., Bernhard W.A. Factors affecting the yields of C1' and C5' oxidation products in radiation-damaged DNA: the indirect effect. Radiat. Res. 2010, 174:645-649.
-
(2010)
Radiat. Res.
, vol.174
, pp. 645-649
-
-
Price, C.S.1
Razskazovskiy, Y.2
Bernhard, W.A.3
-
28
-
-
0033995752
-
Protection against radiation-induced degradation of DNA bases by polyamines
-
Douki T., Bretonniere Y., Cadet J. Protection against radiation-induced degradation of DNA bases by polyamines. Radiat. Res. 2000, 153:29-35.
-
(2000)
Radiat. Res.
, vol.153
, pp. 29-35
-
-
Douki, T.1
Bretonniere, Y.2
Cadet, J.3
-
29
-
-
84455161816
-
Poly(ADP-ribose) polymerase 1 (PARP-1) binds to 8-oxoguanine-DNA glycosylase (OGG1)
-
Hooten N.N., Kompaniez K., Barnes J., Lohani A., Evans M.K. Poly(ADP-ribose) polymerase 1 (PARP-1) binds to 8-oxoguanine-DNA glycosylase (OGG1). J. Biol. Chem. 2011, 286:44679-44690.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 44679-44690
-
-
Hooten, N.N.1
Kompaniez, K.2
Barnes, J.3
Lohani, A.4
Evans, M.K.5
-
30
-
-
25444460601
-
Recognition and incision of gamma-radiation-induced cross-linked guanine-thymine tandem lesion G[8,5-Me]T by UvrABC nuclease
-
Yang Z., Colis L.C., Basu A.K., Zou Y. Recognition and incision of gamma-radiation-induced cross-linked guanine-thymine tandem lesion G[8,5-Me]T by UvrABC nuclease. Chem. Res. Toxicol. 2005, 18:1339-1346.
-
(2005)
Chem. Res. Toxicol.
, vol.18
, pp. 1339-1346
-
-
Yang, Z.1
Colis, L.C.2
Basu, A.K.3
Zou, Y.4
-
31
-
-
0032565577
-
Mutagenicity and repair of oxidative DNA damage: insights from studies using defined lesions
-
Wang D., Kreutzer D.A., Essigmann J.M. Mutagenicity and repair of oxidative DNA damage: insights from studies using defined lesions. Mutat. Res. Fundam. Mol. Mech. Mutagen. 1998, 400:99-115.
-
(1998)
Mutat. Res. Fundam. Mol. Mech. Mutagen.
, vol.400
, pp. 99-115
-
-
Wang, D.1
Kreutzer, D.A.2
Essigmann, J.M.3
-
32
-
-
0033377611
-
Comparison of the mutagenic properties of 8-oxo-7,8-dihydro-2'-deoxyadenosine and 8-oxo-7,8-dihydro-2'-deoxyguanosine DNA lesions in mammalian cells
-
Tan X., Grollman A.P., Shibutani S. Comparison of the mutagenic properties of 8-oxo-7,8-dihydro-2'-deoxyadenosine and 8-oxo-7,8-dihydro-2'-deoxyguanosine DNA lesions in mammalian cells. Carcinogenesis 1999, 20:2287-2292.
-
(1999)
Carcinogenesis
, vol.20
, pp. 2287-2292
-
-
Tan, X.1
Grollman, A.P.2
Shibutani, S.3
-
33
-
-
79956197636
-
Delayed repair of radiation induced clustered DNA damage: friend or foe?
-
Eccles L.J., O'Neill P., Lomax M.E. Delayed repair of radiation induced clustered DNA damage: friend or foe?. Mutat. Res. 2011, 711:134-141.
-
(2011)
Mutat. Res.
, vol.711
, pp. 134-141
-
-
Eccles, L.J.1
O'Neill, P.2
Lomax, M.E.3
-
34
-
-
0027487229
-
AIN-93 purified diets for laboratory rodents: final report of the american institute of nutrition ad hoc writing committee on the reformulation of AIN-76A rodent diet
-
Reeves P.G., Nielsen F.H., Fahey G.C. AIN-93 purified diets for laboratory rodents: final report of the american institute of nutrition ad hoc writing committee on the reformulation of AIN-76A rodent diet. J. Nutr. 1993, 123:1939-1951.
-
(1993)
J. Nutr.
, vol.123
, pp. 1939-1951
-
-
Reeves, P.G.1
Nielsen, F.H.2
Fahey, G.C.3
-
35
-
-
0029012892
-
Assay methods for nicotinamide mononucleotide adenylyltransferase of wide applicability
-
Balducci E., Emanuelli M., Raffaelli N., Ruggieri S., Amici A., Magni G., Orsomando G., Polzonetti V., Natalini P. Assay methods for nicotinamide mononucleotide adenylyltransferase of wide applicability. Anal. Biochem. 1995, 228:64-68.
-
(1995)
Anal. Biochem.
, vol.228
, pp. 64-68
-
-
Balducci, E.1
Emanuelli, M.2
Raffaelli, N.3
Ruggieri, S.4
Amici, A.5
Magni, G.6
Orsomando, G.7
Polzonetti, V.8
Natalini, P.9
-
36
-
-
0015888084
-
An improved cycling assay for nicotinamide adenine dinucleotide
-
Bernofsky C., Swan M. An improved cycling assay for nicotinamide adenine dinucleotide. Anal. Biochem. 1973, 53:452-458.
-
(1973)
Anal. Biochem.
, vol.53
, pp. 452-458
-
-
Bernofsky, C.1
Swan, M.2
-
37
-
-
0343416906
-
+ content strictly depends on ATP concentration in isolated liver cells
-
+ content strictly depends on ATP concentration in isolated liver cells. FEBS Lett. 1997, 410:329-332.
-
(1997)
FEBS Lett.
, vol.410
, pp. 329-332
-
-
Devin, A.1
Guérin, B.2
Rigoulet, M.3
-
38
-
-
0037401302
-
High levels of apoptosis induced by total body irradiation in mice fed a low protein-low vitamin E diet
-
Shin S.J. High levels of apoptosis induced by total body irradiation in mice fed a low protein-low vitamin E diet. Food Chem. Toxicol. 2003, 41:665-670.
-
(2003)
Food Chem. Toxicol.
, vol.41
, pp. 665-670
-
-
Shin, S.J.1
-
39
-
-
0037536623
-
-
CRC, Press, Boca Raton, FL, E.A. Bump, K.K. Malaker (Eds.)
-
Radioprotectors: Chemical, Biological and Clinical Perspective 1998, CRC, Press, Boca Raton, FL. E.A. Bump, K.K. Malaker (Eds.).
-
(1998)
Radioprotectors: Chemical, Biological and Clinical Perspective
-
-
-
40
-
-
84859359102
-
A review of radiation countermeasure work ongoing at the Armed Forces Radiobiology Research Institute
-
Singh V.K., Ducey E.J., Brown D.S., Whitnall M.H. A review of radiation countermeasure work ongoing at the Armed Forces Radiobiology Research Institute. Int. J. Radiat. Biol. 2012, 88:296-310.
-
(2012)
Int. J. Radiat. Biol.
, vol.88
, pp. 296-310
-
-
Singh, V.K.1
Ducey, E.J.2
Brown, D.S.3
Whitnall, M.H.4
-
41
-
-
33750699697
-
Influence of ferulic acid on γ-radiation induced DNA damage, lipid peroxidation and antioxidant status in primary culture of isolated rat hepatocytes
-
Srinivasan M., RamSudheer A., Pillai K.R., RaghuKumar P., Sudhakaran P.R., Menon V.P. Influence of ferulic acid on γ-radiation induced DNA damage, lipid peroxidation and antioxidant status in primary culture of isolated rat hepatocytes. Toxicology 2006, 228:249-258.
-
(2006)
Toxicology
, vol.228
, pp. 249-258
-
-
Srinivasan, M.1
RamSudheer, A.2
Pillai, K.R.3
RaghuKumar, P.4
Sudhakaran, P.R.5
Menon, V.P.6
-
42
-
-
74149092425
-
Enhanced one-carbon flux towards DNA methylation: effect of dietary methyl supplements against gamma-radiation-induced epigenetic modifications
-
Batra V., Sridhar S., Devasagayam T.P. Enhanced one-carbon flux towards DNA methylation: effect of dietary methyl supplements against gamma-radiation-induced epigenetic modifications. Chem. Biol. Interact. 2010, 183:425-433.
-
(2010)
Chem. Biol. Interact.
, vol.183
, pp. 425-433
-
-
Batra, V.1
Sridhar, S.2
Devasagayam, T.P.3
-
44
-
-
79960346496
-
Cancer stem cell overexpression of nicotinamide N-methyltransferase enhances cellular radiation resistance
-
D'Andrea F.P., Safwat A., Kassem M., Gautier L., Overgaard J., Horsman M.R. Cancer stem cell overexpression of nicotinamide N-methyltransferase enhances cellular radiation resistance. Radiother. Oncol. 2011, 99:373-378.
-
(2011)
Radiother. Oncol.
, vol.99
, pp. 373-378
-
-
D'Andrea, F.P.1
Safwat, A.2
Kassem, M.3
Gautier, L.4
Overgaard, J.5
Horsman, M.R.6
-
45
-
-
0014409901
-
Metabolism of pyridinium precursors of pyridine nucleotides in perfused rat liver
-
Hagino Y., Lan S.J., Ng C.Y., Henderson L.M. Metabolism of pyridinium precursors of pyridine nucleotides in perfused rat liver. J. Biol. Chem. 1968, 243:4980-4986.
-
(1968)
J. Biol. Chem.
, vol.243
, pp. 4980-4986
-
-
Hagino, Y.1
Lan, S.J.2
Ng, C.Y.3
Henderson, L.M.4
-
46
-
-
29544433799
-
Directed evolution of metabolic pathways
-
Chatterjee R., Yuan L. Directed evolution of metabolic pathways. Trends Biotechnol. 2006, 24:28-38.
-
(2006)
Trends Biotechnol.
, vol.24
, pp. 28-38
-
-
Chatterjee, R.1
Yuan, L.2
-
47
-
-
62649156291
-
Nampt: linking NAD biology, metabolism and cancer
-
Garten A., Petzold S., Körner A., Imai S., Kiess W. Nampt: linking NAD biology, metabolism and cancer. Trends. Endocrinol. Metab. 2009, 20:130-138.
-
(2009)
Trends. Endocrinol. Metab.
, vol.20
, pp. 130-138
-
-
Garten, A.1
Petzold, S.2
Körner, A.3
Imai, S.4
Kiess, W.5
-
48
-
-
2342507720
-
A.P. endonuclease and poly(ADP-ribose) polymerase-1 interact with the same base excision repair intermediate
-
Cistulli C., Lavrik O.I., Prasad R., Hou E., Wilson S.H. A.P. endonuclease and poly(ADP-ribose) polymerase-1 interact with the same base excision repair intermediate. DNA Repair 2004, 3:581-591.
-
(2004)
DNA Repair
, vol.3
, pp. 581-591
-
-
Cistulli, C.1
Lavrik, O.I.2
Prasad, R.3
Hou, E.4
Wilson, S.H.5
-
49
-
-
0034720734
-
Base excision repair is impaired in mammalian cells lacking poly(ADP-ribose) polymerase-1
-
Dantzer F., de La Rubia G., Ménissier-De Murcia J., Hostomsky Z., de Murcia G., Schreiber V. Base excision repair is impaired in mammalian cells lacking poly(ADP-ribose) polymerase-1. Biochemistry 2000, 39:7559-7569.
-
(2000)
Biochemistry
, vol.39
, pp. 7559-7569
-
-
Dantzer, F.1
de La Rubia, G.2
Ménissier-De Murcia, J.3
Hostomsky, Z.4
de Murcia, G.5
Schreiber, V.6
-
50
-
-
84859248021
-
DNA damage in nijmegen breakage syndrome cells leads to PARP hyperactivation and increased oxidative stress
-
Krenzlin H., Demuth I., Salewsky B., Wessendorf P., Weidele K., Bürkle A., Digweed M. DNA damage in nijmegen breakage syndrome cells leads to PARP hyperactivation and increased oxidative stress. PLoS Genet. 2012, 8:e1002557.
-
(2012)
PLoS Genet.
, vol.8
-
-
Krenzlin, H.1
Demuth, I.2
Salewsky, B.3
Wessendorf, P.4
Weidele, K.5
Bürkle, A.6
Digweed, M.7
-
51
-
-
40849119972
-
+ and vitamin B3: from metabolism to therapies
-
+ and vitamin B3: from metabolism to therapies. J. Pharmacol. Exp. Ther. 2008, 324:883-893.
-
(2008)
J. Pharmacol. Exp. Ther.
, vol.324
, pp. 883-893
-
-
Sauve, A.A.1
-
52
-
-
84860584591
-
Niacin requirements for genomic stability
-
Kirkland J.B. Niacin requirements for genomic stability. Mutat. Res. 2012, 733:14-20.
-
(2012)
Mutat. Res.
, vol.733
, pp. 14-20
-
-
Kirkland, J.B.1
-
53
-
-
84858774472
-
The ups and downs of DNA repair biomarkers for PARP inhibitor therapies
-
Wang X., Weaver D.T. The ups and downs of DNA repair biomarkers for PARP inhibitor therapies. Am. J. Cancer Res. 2011, 1:301-327.
-
(2011)
Am. J. Cancer Res.
, vol.1
, pp. 301-327
-
-
Wang, X.1
Weaver, D.T.2
-
54
-
-
34548627517
-
Nutrient-sensitive mitochondrial NAD+ levels dictate cell survival
-
Yang H., Yang T., Baur J.A., Perez E., Matsui T., Carmona J.J., Lamming D.W., Souza-Pinto N.C., Bohr V.A., Rosenzweig A., Cabo R., Sauve A.A., Sinclair D.A. Nutrient-sensitive mitochondrial NAD+ levels dictate cell survival. Cell 2007, 130:1095-1107.
-
(2007)
Cell
, vol.130
, pp. 1095-1107
-
-
Yang, H.1
Yang, T.2
Baur, J.A.3
Perez, E.4
Matsui, T.5
Carmona, J.J.6
Lamming, D.W.7
Souza-Pinto, N.C.8
Bohr, V.A.9
Rosenzweig, A.10
Cabo, R.11
Sauve, A.A.12
Sinclair, D.A.13
-
55
-
-
70349978979
-
Aprataxin, poly-ADP ribose polymerase 1 (PARP-1) and apurinic endonuclease 1 (APE1) function together to protect the genome against oxidative damage
-
Harris J.L., Jakob B., Taucher-Scholz G., Dianov G.L., Becherel O.J., Lavin M.F. Aprataxin, poly-ADP ribose polymerase 1 (PARP-1) and apurinic endonuclease 1 (APE1) function together to protect the genome against oxidative damage. Hum. Mol. Genet. 2009, 18:4102-4117.
-
(2009)
Hum. Mol. Genet.
, vol.18
, pp. 4102-4117
-
-
Harris, J.L.1
Jakob, B.2
Taucher-Scholz, G.3
Dianov, G.L.4
Becherel, O.J.5
Lavin, M.F.6
-
56
-
-
0345448125
-
Repair of abasic sites in DNA
-
Dianov G.L., Sleeth K.M., Dianova I.I., Allinson S.L. Repair of abasic sites in DNA. Mutat. Res. 2003, 531:157-163.
-
(2003)
Mutat. Res.
, vol.531
, pp. 157-163
-
-
Dianov, G.L.1
Sleeth, K.M.2
Dianova, I.I.3
Allinson, S.L.4
-
57
-
-
61349196954
-
Base excision repair of reactive oxygen species-initiated 7,8-dihydro-8-oxo-2'-deoxyguanosine inhibits the cytotoxicity of platinum anticancer drugs, Mol
-
Preston T.J., Henderson J.T., McCallum G.P., Wells P.G. Base excision repair of reactive oxygen species-initiated 7,8-dihydro-8-oxo-2'-deoxyguanosine inhibits the cytotoxicity of platinum anticancer drugs, Mol. Cancer Ther. 2009, 8:2015-2026.
-
(2009)
Cancer Ther.
, vol.8
, pp. 2015-2026
-
-
Preston, T.J.1
Henderson, J.T.2
McCallum, G.P.3
Wells, P.G.4
-
58
-
-
0031469841
-
Analysis of a form of oxidative DNA damage, 8-hydroxy-2'-deoxyguanosine, as a marker of cellular oxidative stress during carcinogenesis
-
Kasai H. Analysis of a form of oxidative DNA damage, 8-hydroxy-2'-deoxyguanosine, as a marker of cellular oxidative stress during carcinogenesis. Mutat. Res. Rev. Mutat. Res. 1997, 387:147-163.
-
(1997)
Mutat. Res. Rev. Mutat. Res.
, vol.387
, pp. 147-163
-
-
Kasai, H.1
-
59
-
-
84870396074
-
Nicotinamide supplementation protects gestational diabetic rats by reducing oxidative stress and enhancing immune responses
-
John C.M., Ramasamy R., Naqeeb A.l., Nuaimi A.H., Adam A. Nicotinamide supplementation protects gestational diabetic rats by reducing oxidative stress and enhancing immune responses. Curr. Med. Chem. 2012, 19:5181-5186.
-
(2012)
Curr. Med. Chem.
, vol.19
, pp. 5181-5186
-
-
John, C.M.1
Ramasamy, R.2
Naqeeb, A.3
Nuaimi, A.H.4
Adam, A.5
-
60
-
-
84864137382
-
A dual role for poly(ADP-ribose) polymerase-1 during caspase-dependent apoptosis
-
Zhang F., Lau S.S., Monks T.J. A dual role for poly(ADP-ribose) polymerase-1 during caspase-dependent apoptosis. Toxicol. Sci. 2012, 128:103-114.
-
(2012)
Toxicol. Sci.
, vol.128
, pp. 103-114
-
-
Zhang, F.1
Lau, S.S.2
Monks, T.J.3
-
61
-
-
69549117127
-
A phosphoenzyme mimic, overlapping catalytic sites and reaction coordinate motion for human NAMPT
-
Burgos E.S., Ho M.C., Almo S.C., Schramm V.L. A phosphoenzyme mimic, overlapping catalytic sites and reaction coordinate motion for human NAMPT. Proc. Natl. Acad. Sci. U.S.A. 2009, 106:13748-13753.
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 13748-13753
-
-
Burgos, E.S.1
Ho, M.C.2
Almo, S.C.3
Schramm, V.L.4
-
62
-
-
33751113602
-
Mammalian sirtuins-emerging roles in physiology, aging, and calorie restriction
-
Haigis M.C., Guarente L.P. Mammalian sirtuins-emerging roles in physiology, aging, and calorie restriction. Genes & Dev. 2006, 20:2913-2921.
-
(2006)
Genes & Dev.
, vol.20
, pp. 2913-2921
-
-
Haigis, M.C.1
Guarente, L.P.2
-
63
-
-
77953356423
-
Genetic variation in the visfatin (PBEF1/NAMPT) gene and type 2 diabetes in the Greek population
-
Paschou P., Kukuvitis A., Yavropoulou M.P., Dritsoula A., Giapoutzidis V., Anastasiou O., Kazakos K., Yovos J.G. Genetic variation in the visfatin (PBEF1/NAMPT) gene and type 2 diabetes in the Greek population. Cytokine 2010, 51:25-27.
-
(2010)
Cytokine
, vol.51
, pp. 25-27
-
-
Paschou, P.1
Kukuvitis, A.2
Yavropoulou, M.P.3
Dritsoula, A.4
Giapoutzidis, V.5
Anastasiou, O.6
Kazakos, K.7
Yovos, J.G.8
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