Aprataxin, poly-ADP ribose polymerase 1 (PARP-1) and apurinic endonuclease 1 (APE1) function together to protect the genome against oxidative damage

Human Molecular Genetics

Volumn 18, Issue 21, 2009, Pages 4102-4117

  Harris, Janelle L ^a,b   Jakob, Burkhard ^c   Taucher Scholz, Gisela ^c   Dianov, Grigory L ^d   Becherel, Olivier J ^a   Lavin, Martin F ^a,e  

^a QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^b QUEENSLAND UNIVERSITY OF TECHNOLOGY   (Australia)

^c GSI HELMHOLTZZENTRUM FÜR SCHWERIONENFORSCHUNG GMBH   (Germany)

^d UNIVERSITY OF OXFORD   (United Kingdom)

^e UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

APRATAXIN; APURINIC ENDONUCLEASE 1; CELL PROTEIN; DNA (APURINIC OR APYRIMIDINIC SITE) LYASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; PROTEIN OGG1; UNCLASSIFIED DRUG;

ADENYLATION; ANIMAL CELL; ARTICLE; ATAXIA WITH OCULOMOTOR APRAXIA TYPE 1; CONTROLLED STUDY; DNA DAMAGE; DNA FLANKING REGION; ENZYME ACTIVITY; ENZYME INHIBITION; EXCISION REPAIR; HUMAN; HUMAN CELL; IN VITRO STUDY; MALE; NEUROLOGIC DISEASE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION;

ANIMALS; BINDING SITES; CELL LINE; CELLS, CULTURED; DNA DAMAGE; DNA GLYCOSYLASES; DNA REPAIR; DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE; DNA-BINDING PROTEINS; FIBROBLASTS; GREEN FLUORESCENT PROTEINS; HELA CELLS; HUMANS; HYDROGEN PEROXIDE; IMMUNOBLOTTING; MICE; MICE, KNOCKOUT; MICROSCOPY, CONFOCAL; NUCLEAR PROTEINS; OXIDATIVE STRESS; POLY(ADP-RIBOSE) POLYMERASES; PROTEIN BINDING; PROTEIN INTERACTION MAPPING; SPINOCEREBELLAR ATAXIAS;

EID: 70349978979     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddp359     Document Type: Article

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