A phosphoenzyme mimic, overlapping catalytic sites and reaction coordinate motion for human NAMPT

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 33, 2009, Pages 13748-13753

  Burgos, Emmanuel S ^a   Ho, Meng Chiao ^a   Almo, Steven C ^a   Schramm, Vern L ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

NAD+ regulation; Nicotinamide; Nicotinamide phosphoribosyltransferase; Phosphohistidine; Phosphoribosyltransferase

Indexed keywords

NICOTINAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE;

ARTICLE; CRYSTAL STRUCTURE; ENZYME PHOSPHORYLATION; ENZYME STRUCTURE; HUMAN; PRIORITY JOURNAL;

ADENOSINE TRIPHOSPHATASES; ADENOSINE TRIPHOSPHATE; BINDING SITES; CATALYSIS; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; DIPHOSPHATES; ENZYME ACTIVATION; HISTIDINE; HUMANS; KINETICS; MOTION; NIACINAMIDE; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; PHOSPHORYLATION; SUBSTRATE SPECIFICITY;

EID: 69549117127     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0903898106     Document Type: Article

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