Suppression of the notch signaling pathway by γ-secretase inhibitor GSI inhibits human nasopharyngeal carcinoma cell proliferation

Cancer Letters

Volumn 306, Issue 1, 2011, Pages 76-84

  Chen, Shi Ming ^a,b   Liu, Jun Ping ^b   Zhou, Jun Xu ^a   Chen, Chen ^a   Deng, Yu Qin ^a   Wang, Yan ^a   Tao, Ze Zhang ^a  

^a RENMIN HOSPITAL OF WUHAN UNIVERSITY   (China)

^b MONASH UNIVERSITY   (Australia)

Author keywords

AKT; Apoptosis; GSI; Nasopharyngeal carcinoma cells; Notch

Indexed keywords

GAMMA SECRETASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE KINASE; NOTCH1 RECEPTOR; NOTCH2 RECEPTOR; NOTCH4 RECEPTOR; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CARCINOMA CELL; CELL CYCLE ARREST; CELL LEVEL; CELL PROLIFERATION; CELL SURVIVAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG SELECTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; NASOPHARYNX CARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

AMYLOID PRECURSOR PROTEIN SECRETASES; APOPTOSIS; BISBENZIMIDAZOLE; CARCINOMA; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; DNA; ENZYME INHIBITORS; FLUORESCENT DYES; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MEMBRANE POTENTIALS; MODELS, BIOLOGICAL; NASOPHARYNGEAL NEOPLASMS; RECEPTORS, NOTCH;

EID: 79955471162     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2011.02.034     Document Type: Article

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