Down-regulation of Notch signaling by a γ-secretase inhibitor enhances the radiosensitivity of nasopharyngeal carcinoma cells

Oncology Reports

Volumn 26, Issue 5, 2011, Pages 1323-1328

  Yu, Shudong ^a   Zhang, Ruxin ^a   Liu, Fenye ^b   Hu, Hua ^a   Yu, Shaoqing ^a   Wang, Hong ^a  

^a FUDAN UNIVERSITY   (China)

^b SHANDONG UNIVERSITY   (China)

Author keywords

secretase inhibitor; Nasopharyngeal carcinoma; Notch signaling; Radiosensitization

Indexed keywords

[N [(3,5 DIFLUOROPHENYL)ACETYL]ALANYL 2 PHENYL]GLYCINE 1,1 DIMETHYLETHYL ESTER; GAMMA SECRETASE INHIBITOR; NOTCH1 RECEPTOR; RADIOSENSITIZING AGENT; UNCLASSIFIED DRUG;

APOPTOSIS ASSAY; ARTICLE; ASSAY; CANCER CELL; CANCER INHIBITION; CELL SURVIVAL; COLONY FORMATION ASSAY; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; HUMAN; HUMAN CELL; IN VITRO STUDY; NASOPHARYNX CARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIOSENSITIVITY; SIGNAL TRANSDUCTION;

AMYLOID PRECURSOR PROTEIN SECRETASES; CELL LINE, TUMOR; COMBINED MODALITY THERAPY; DIPEPTIDES; DOWN-REGULATION; HUMANS; NASOPHARYNGEAL NEOPLASMS; RADIATION TOLERANCE; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION;

EID: 80053162884     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2011.1402     Document Type: Article

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