-
1
-
-
0034209203
-
New consensus research on neuropathological aspects of familial amyotrophic lateral sclerosis with superoxide dismutase 1 (sod1) gene mutations: Inclusions containing sod1 in neurons and astrocytes
-
Kato, S.; Takikawa, M.; Nakashima, K.; Hirano, A.; Cleveland, D.W.; Kusaka, H.; Shibata, N.; Kato, M.; Nakano, I.; Ohama, E. New consensus research on neuropathological aspects of familial amyotrophic lateral sclerosis with superoxide dismutase 1 (sod1) gene mutations: Inclusions containing sod1 in neurons and astrocytes. Amyotrophic Lateral Scler. Other Mot. Neuron Disord. 2000, 1, 163-184.
-
(2000)
Amyotrophic Lateral Scler. Other Mot. Neuron Disord
, vol.1
, pp. 163-184
-
-
Kato, S.1
Takikawa, M.2
Nakashima, K.3
Hirano, A.4
Cleveland, D.W.5
Kusaka, H.6
Shibata, N.7
Kato, M.8
Nakano, I.9
Ohama, E.10
-
2
-
-
0027401203
-
Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
-
Rosen, D.R.; Siddique, T.; Patterson, D.; Figlewicz, D.A.; Sapp, P.; Hentati, A.; Donaldson, D.; Goto, J.; O'Regan, J.P.; Deng, H.X.; et al. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 1993, 362, 59-62.
-
(1993)
Nature
, vol.362
, pp. 59-62
-
-
Rosen, D.R.1
Siddique, T.2
Patterson, D.3
Figlewicz, D.A.4
Sapp, P.5
Hentati, A.6
Donaldson, D.7
Goto, J.8
O'Regan, J.P.9
Deng, H.X.10
-
3
-
-
77955352066
-
Novel antibodies reveal inclusions containing non-native SOD1 in sporadic als patients
-
Forsberg, K.; Jonsson, P.A.; Andersen, P.M.; Bergemalm, D.; Graffmo, K.S.; Hultdin, M.; Jacobsson, J.; Rosquist, R.; Marklund, S.L.; Brannstrom, T. Novel antibodies reveal inclusions containing non-native SOD1 in sporadic als patients. PLoS One 2010, 5, e11552.
-
(2010)
PLoS One
, vol.5
-
-
Forsberg, K.1
Jonsson, P.A.2
Andersen, P.M.3
Bergemalm, D.4
Graffmo, K.S.5
Hultdin, M.6
Jacobsson, J.7
Rosquist, R.8
Marklund, S.L.9
Brannstrom, T.10
-
4
-
-
0029842923
-
Immunohistochemical study on superoxide dismutases in spinal cords from autopsied patients with amyotrophic lateral sclerosis
-
Shibata, N.; Asayama, K.; Hirano, A.; Kobayashi, M. Immunohistochemical study on superoxide dismutases in spinal cords from autopsied patients with amyotrophic lateral sclerosis. Dev. Neurosci. 1996, 18, 492-498.
-
(1996)
Dev. Neurosci
, vol.18
, pp. 492-498
-
-
Shibata, N.1
Asayama, K.2
Hirano, A.3
Kobayashi, M.4
-
5
-
-
79958135335
-
Glial nuclear aggregates of superoxide dismutase-1 are regularly present in patients with amyotrophic lateral sclerosis
-
Forsberg, K.; Andersen, P.M.; Marklund, S.L.; Brannstrom, T. Glial nuclear aggregates of superoxide dismutase-1 are regularly present in patients with amyotrophic lateral sclerosis. Acta Neuropathol. 2011, 121, 623-634.
-
(2011)
Acta Neuropathol
, vol.121
, pp. 623-634
-
-
Forsberg, K.1
Andersen, P.M.2
Marklund, S.L.3
Brannstrom, T.4
-
6
-
-
37849007550
-
Oxidized/misfolded superoxide dismutase-1: The cause of all amyotrophic lateral sclerosis?
-
Kabashi, E.; Valdmanis, P.N.; Dion, P.; Rouleau, G.A. Oxidized/misfolded superoxide dismutase-1: The cause of all amyotrophic lateral sclerosis? Ann. Neurol. 2007, 62, 553-559.
-
(2007)
Ann. Neurol
, vol.62
, pp. 553-559
-
-
Kabashi, E.1
Valdmanis, P.N.2
Dion, P.3
Rouleau, G.A.4
-
7
-
-
34547640096
-
Common molecular signature in sod1 for both sporadic and familial amyotrophic lateral sclerosis
-
Gruzman, A.; Wood, W.L.; Alpert, E.; Prasad, M.D.; Miller, R.G.; Rothstein, J.D.; Bowser, R.; Hamilton, R.; Wood, T.D.; Cleveland, D.W.; et al. Common molecular signature in sod1 for both sporadic and familial amyotrophic lateral sclerosis. Proc. Natl. Acad. Sci. USA 2007, 104, 12524-12529.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 12524-12529
-
-
Gruzman, A.1
Wood, W.L.2
Alpert, E.3
Prasad, M.D.4
Miller, R.G.5
Rothstein, J.D.6
Bowser, R.7
Hamilton, R.8
Wood, T.D.9
Cleveland, D.W.10
-
8
-
-
0035664213
-
Histological evidence of protein aggregation in mutant sod1 transgenic mice and in amyotrophic lateral sclerosis neural tissues
-
Watanabe, M.; Dykes-Hoberg, M.; Culotta, V.C.; Price, D.L.; Wong, P.C.; Rothstein, J.D. Histological evidence of protein aggregation in mutant sod1 transgenic mice and in amyotrophic lateral sclerosis neural tissues. Neurobiol. Dis. 2001, 8, 933-941.
-
(2001)
Neurobiol. Dis
, vol.8
, pp. 933-941
-
-
Watanabe, M.1
Dykes-Hoberg, M.2
Culotta, V.C.3
Price, D.L.4
Wong, P.C.5
Rothstein, J.D.6
-
9
-
-
0032544674
-
Aggregation and motor neuron toxicity of an ALS-linked SOD1 mutant independent from wild-type SOD1
-
Bruijn, L.I.; Houseweart, M.K.; Kato, S.; Anderson, K.L.; Anderson, S.D.; Ohama, E.; Reaume, A.G.; Scott, R.W.; Cleveland, D.W. Aggregation and motor neuron toxicity of an ALS-linked SOD1 mutant independent from wild-type SOD1. Science 1998, 281, 1851-1854.
-
(1998)
Science
, vol.281
, pp. 1851-1854
-
-
Bruijn, L.I.1
Houseweart, M.K.2
Kato, S.3
Anderson, K.L.4
Anderson, S.D.5
Ohama, E.6
Reaume, A.G.7
Scott, R.W.8
Cleveland, D.W.9
-
10
-
-
74049164709
-
Non-cell autonomous toxicity in neurodegenerative disorders: Als and beyond
-
Ilieva, H.; Polymenidou, M.; Cleveland, D.W. Non-cell autonomous toxicity in neurodegenerative disorders: Als and beyond. J. Cell Biol. 2009, 187, 761-772.
-
(2009)
J. Cell Biol
, vol.187
, pp. 761-772
-
-
Ilieva, H.1
Polymenidou, M.2
Cleveland, D.W.3
-
11
-
-
77952570883
-
Four familial als pedigrees discordant for two SOD1 mutations: Are all SOD1 mutations pathogenic?
-
Felbecker, A.; Camu, W.; Valdmanis, P.N.; Sperfeld, A.D.; Waibel, S.; Steinbach, P.; Rouleau, G.A.; Ludolph, A.C.; Andersen, P.M. Four familial als pedigrees discordant for two SOD1 mutations: Are all SOD1 mutations pathogenic? J. Neurol. Neurosurg. Psychiatry 2010, 81, 572-577.
-
(2010)
J. Neurol. Neurosurg. Psychiatry
, vol.81
, pp. 572-577
-
-
Felbecker, A.1
Camu, W.2
Valdmanis, P.N.3
Sperfeld, A.D.4
Waibel, S.5
Steinbach, P.6
Rouleau, G.A.7
Ludolph, A.C.8
Andersen, P.M.9
-
12
-
-
84872611309
-
Extracellular aggregated Cu/Zn superoxide dismutase activates microglia to give a cytotoxic phenotype
-
Roberts, K.; Zeineddine, R.; Corcoran, L.; Li, W.; Campbell, I.L.; Yerbury, J.J. Extracellular aggregated Cu/Zn superoxide dismutase activates microglia to give a cytotoxic phenotype. Glia 2013, 61, 409-419.
-
(2013)
Glia
, vol.61
, pp. 409-419
-
-
Roberts, K.1
Zeineddine, R.2
Corcoran, L.3
Li, W.4
Campbell, I.L.5
Yerbury, J.J.6
-
13
-
-
79952743365
-
Prion-like propagation of mutant superoxide dismutase-1 misfolding in neuronal cells
-
Munch, C.; O'Brien, J.; Bertolotti, A. Prion-like propagation of mutant superoxide dismutase-1 misfolding in neuronal cells. Proc. Natl. Acad. Sci. USA 2011, 108, 3548-3553.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 3548-3553
-
-
Munch, C.1
O'Brien, J.2
Bertolotti, A.3
-
14
-
-
84858280794
-
Als patients with mutations in the sod1 gene have an unique metabolomic profile in the cerebrospinal fluid compared with als patients without mutations
-
Wuolikainen, A.; Andersen, P.M.; Moritz, T.; Marklund, S.L.; Antti, H. Als patients with mutations in the sod1 gene have an unique metabolomic profile in the cerebrospinal fluid compared with als patients without mutations. Mol. Genet. Metab. 2012, 105, 472-478.
-
(2012)
Mol. Genet. Metab
, vol.105
, pp. 472-478
-
-
Wuolikainen, A.1
Andersen, P.M.2
Moritz, T.3
Marklund, S.L.4
Antti, H.5
-
15
-
-
84863462965
-
Csf markers in amyotrophic lateral sclerosis
-
Tarasiuk, J.; Kulakowska, A.; Drozdowski, W.; Kornhuber, J.; Lewczuk, P. Csf markers in amyotrophic lateral sclerosis. J. Neural Transm. 2012, 119, 747-757.
-
(2012)
J. Neural Transm
, vol.119
, pp. 747-757
-
-
Tarasiuk, J.1
Kulakowska, A.2
Drozdowski, W.3
Kornhuber, J.4
Lewczuk, P.5
-
16
-
-
79953717156
-
Disease-related changes in the cerebrospinal fluid metabolome in amyotrophic lateral sclerosis detected by gc/tofms
-
Wuolikainen, A.; Moritz, T.; Marklund, S.L.; Antti, H.; Andersen, P.M. Disease-related changes in the cerebrospinal fluid metabolome in amyotrophic lateral sclerosis detected by gc/tofms. PLoS One 2011, 6, e17947.
-
(2011)
PLoS One
, vol.6
-
-
Wuolikainen, A.1
Moritz, T.2
Marklund, S.L.3
Antti, H.4
Andersen, P.M.5
-
17
-
-
34047245280
-
Metabolic progression markers of neurodegeneration in the transgenic g93a-sod1 mouse model of amyotrophic lateral sclerosis
-
Niessen, H.G.; Debska-Vielhaber, G.; Sander, K.; Angenstein, F.; Ludolph, A.C.; Hilfert, L.; Willker, W.; Leibfritz, D.; Heinze, H.J.; Kunz, W.S.; et al. Metabolic progression markers of neurodegeneration in the transgenic g93a-sod1 mouse model of amyotrophic lateral sclerosis. Eur. J. Neurosci. 2007, 25, 1669-1677.
-
(2007)
Eur. J. Neurosci
, vol.25
, pp. 1669-1677
-
-
Niessen, H.G.1
Debska-Vielhaber, G.2
Sander, K.3
Angenstein, F.4
Ludolph, A.C.5
Hilfert, L.6
Willker, W.7
Leibfritz, D.8
Heinze, H.J.9
Kunz, W.S.10
-
18
-
-
0037474171
-
The Cu, Zn superoxide dismutase in neuroblastoma SK-N-BE cells is exported by a microvesicles dependent pathway
-
Mondola, P.; Ruggiero, G.; Seru, R.; Damiano, S.; Grimaldi, S.; Garbi, C.; Monda, M.; Greco, D.; Santillo, M. The Cu, Zn superoxide dismutase in neuroblastoma SK-N-BE cells is exported by a microvesicles dependent pathway. Brain Res. Mol. Brain Res. 2003, 110, 45-51.
-
(2003)
Brain Res. Mol. Brain Res
, vol.110
, pp. 45-51
-
-
Mondola, P.1
Ruggiero, G.2
Seru, R.3
Damiano, S.4
Grimaldi, S.5
Garbi, C.6
Monda, M.7
Greco, D.8
Santillo, M.9
-
19
-
-
29444443348
-
Chromogranin-mediated secretion of mutant superoxide dismutase proteins linked to amyotrophic lateral sclerosis
-
Urushitani, M.; Sik, A.; Sakurai, T.; Nukina, N.; Takahashi, R.; Julien, J.P. Chromogranin-mediated secretion of mutant superoxide dismutase proteins linked to amyotrophic lateral sclerosis. Nat. Neurosci. 2006, 9, 108-118.
-
(2006)
Nat. Neurosci
, vol.9
, pp. 108-118
-
-
Urushitani, M.1
Sik, A.2
Sakurai, T.3
Nukina, N.4
Takahashi, R.5
Julien, J.P.6
-
20
-
-
0034956740
-
Superoxide dismutase in csf from amyotrophic lateral sclerosis patients with and without Cu/Zn-superoxide dismutase mutations
-
Jacobsson, J.; Jonsson, P.A.; Andersen, P.M.; Forsgren, L.; Marklund, S.L. Superoxide dismutase in csf from amyotrophic lateral sclerosis patients with and without Cu/Zn-superoxide dismutase mutations. Brain 2001, 124, 1461-1466.
-
(2001)
Brain
, vol.124
, pp. 1461-1466
-
-
Jacobsson, J.1
Jonsson, P.A.2
Andersen, P.M.3
Forsgren, L.4
Marklund, S.L.5
-
21
-
-
79952572373
-
Misfolded superoxide dismutase-1 in CSF from amyotrophic lateral sclerosis patients
-
Zetterström, P.; Andersen, P.M.; Brännström, T.; Marklund, S.L. Misfolded superoxide dismutase-1 in CSF from amyotrophic lateral sclerosis patients. J. Neurochem. 2011, 117, 91-99.
-
(2011)
J. Neurochem
, vol.117
, pp. 91-99
-
-
Zetterström, P.1
Andersen, P.M.2
Brännström, T.3
Marklund, S.L.4
-
22
-
-
84874905513
-
Protein misfolding in disease and small molecule therapies
-
Gomes, C.M. Protein misfolding in disease and small molecule therapies. Curr. Top. Med. Chem. 2012, 12, 2460-2469.
-
(2012)
Curr. Top. Med. Chem
, vol.12
, pp. 2460-2469
-
-
Gomes, C.M.1
-
23
-
-
84874923658
-
Cofactors and metabolites as protein folding helpers in metabolic diseases
-
Rodrigues, J.V.; Henriques, B.J.; Lucas, T.G.; Gomes, C.M. Cofactors and metabolites as protein folding helpers in metabolic diseases. Curr. Top. Med. Chem. 2012, 12, 2546-2559.
-
(2012)
Curr. Top. Med. Chem
, vol.12
, pp. 2546-2559
-
-
Rodrigues, J.V.1
Henriques, B.J.2
Lucas, T.G.3
Gomes, C.M.4
-
24
-
-
80054078305
-
Cofactors and metabolites as potential stabilizers of mitochondrial acyl-coa dehydrogenases
-
Lucas, T.G.; Henriques, B.J.; Rodrigues, J.V.; Bross, P.; Gregersen, N.; Gomes, C.M. Cofactors and metabolites as potential stabilizers of mitochondrial acyl-coa dehydrogenases. Biochim. Biophys. Acta 2011, 1812, 1658-1663.
-
(2011)
Biochim. Biophys. Acta
, vol.1812
, pp. 1658-1663
-
-
Lucas, T.G.1
Henriques, B.J.2
Rodrigues, J.V.3
Bross, P.4
Gregersen, N.5
Gomes, C.M.6
-
25
-
-
50149112642
-
Protein misfolding in conformational disorders: Rescue of folding defects and chemical chaperoning
-
Leandro, P.; Gomes, C.M. Protein misfolding in conformational disorders: Rescue of folding defects and chemical chaperoning. Mini Rev. Med. Chem. 2008, 8, 901-911.
-
(2008)
Mini Rev. Med. Chem
, vol.8
, pp. 901-911
-
-
Leandro, P.1
Gomes, C.M.2
-
26
-
-
84864548981
-
Metal ions as modulators of protein conformation and misfolding in neurodegeneration
-
Leal, S.S.; Botelho, H.M.; Gomes, C.M. Metal ions as modulators of protein conformation and misfolding in neurodegeneration. Coord. Chem. Rev. 2012, 256, 2253-2270.
-
(2012)
Coord. Chem. Rev
, vol.256
, pp. 2253-2270
-
-
Leal, S.S.1
Botelho, H.M.2
Gomes, C.M.3
-
27
-
-
0031005995
-
Aggregation of beta-amyloid peptide is promoted by membrane phospholipid metabolites elevated in Alzheimer's disease brain
-
Klunk, W.E.; Xu, C.J.; McClure, R.J.; Panchalingam, K.; Stanley, J.A.; Pettegrew, J.W. Aggregation of beta-amyloid peptide is promoted by membrane phospholipid metabolites elevated in Alzheimer's disease brain. J. Neurochem. 1997, 69, 266-272.
-
(1997)
J. Neurochem
, vol.69
, pp. 266-272
-
-
Klunk, W.E.1
Xu, C.J.2
McClure, R.J.3
Panchalingam, K.4
Stanley, J.A.5
Pettegrew, J.W.6
-
28
-
-
78650634568
-
Regulation of in vitro abeta1-40 aggregation mediated by small molecules
-
Kim, H.Y.; Kim, Y.; Han, G.; Kim, D.J. Regulation of in vitro abeta1-40 aggregation mediated by small molecules. J. Alzheimer's Dis. 2010, 22, 73-85.
-
(2010)
J. Alzheimer's Dis
, vol.22
, pp. 73-85
-
-
Kim, H.Y.1
Kim, Y.2
Han, G.3
Kim, D.J.4
-
29
-
-
84860112673
-
Inhibition of aggregation of amyloid beta42 by arginine-containing small compounds
-
Kawasaki, T.; Kamijo, S. Inhibition of aggregation of amyloid beta42 by arginine-containing small compounds. Biosci. Biotechnol. Biochem. 2012, 76, 762-766.
-
(2012)
Biosci. Biotechnol. Biochem
, vol.76
, pp. 762-766
-
-
Kawasaki, T.1
Kamijo, S.2
-
30
-
-
13744262405
-
Contribution of simple saccharides to the stabilization of amyloid structure
-
Fung, J.; Darabie, A.A.; McLaurin, J. Contribution of simple saccharides to the stabilization of amyloid structure. Biochem. Biophys. Res. Commun. 2005, 328, 1067-1072.
-
(2005)
Biochem. Biophys. Res. Commun
, vol.328
, pp. 1067-1072
-
-
Fung, J.1
Darabie, A.A.2
McLaurin, J.3
-
31
-
-
79955426954
-
Chemical library screening identifies a small molecule that downregulates sod1 transcription for drugs to treat amyotrophic lateral sclerosis
-
Murakami, G.; Inoue, H.; Tsukita, K.; Asai, Y.; Amagai, Y.; Aiba, K.; Shimogawa, H.; Uesugi, M.; Nakatsuji, N.; Takahashi, R. Chemical library screening identifies a small molecule that downregulates sod1 transcription for drugs to treat amyotrophic lateral sclerosis. J. Biomol. Screen. 2011, 16, 405-414.
-
(2011)
J. Biomol. Screen
, vol.16
, pp. 405-414
-
-
Murakami, G.1
Inoue, H.2
Tsukita, K.3
Asai, Y.4
Amagai, Y.5
Aiba, K.6
Shimogawa, H.7
Uesugi, M.8
Nakatsuji, N.9
Takahashi, R.10
-
32
-
-
84877256610
-
Recent progress in the discovery of small molecules for the treatment of amyotrophic lateral sclerosis (ALS)
-
Limpert, A.S.; Mattmann, M.E.; Cosford, N.D. Recent progress in the discovery of small molecules for the treatment of amyotrophic lateral sclerosis (ALS). Beilstein J. Org. Chem. 2013, 9, 717-732.
-
(2013)
Beilstein J. Org. Chem
, vol.9
, pp. 717-732
-
-
Limpert, A.S.1
Mattmann, M.E.2
Cosford, N.D.3
-
33
-
-
14844361966
-
Small-molecule-mediated stabilization of familial amyotrophic lateral sclerosis-linked superoxide dismutase mutants against unfolding and aggregation
-
Ray, S.S.; Nowak, R.J.; Brown, R.H., Jr.; Lansbury, P.T., Jr. Small-molecule-mediated stabilization of familial amyotrophic lateral sclerosis-linked superoxide dismutase mutants against unfolding and aggregation. Proc. Natl. Acad. Sci. USA 2005, 102, 3639-3644.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 3639-3644
-
-
Ray, S.S.1
Nowak, R.J.2
Brown Jr., R.H.3
Lansbury Jr., P.T.4
-
34
-
-
80655137663
-
Protein folding inside the cell
-
Wittung-Stafshede, P. Protein folding inside the cell. Biophys. J. 2011, 101, 265-266.
-
(2011)
Biophys. J
, vol.101
, pp. 265-266
-
-
Wittung-Stafshede, P.1
-
35
-
-
84874914445
-
Enhancing mitochondrial calcium buffering capacity reduces aggregation of misfolded SOD1 and motor neuron cell death without extending survival in mouse models of inherited amyotrophic lateral sclerosis
-
Parone, P.A.; da Cruz, S.; Han, J.S.; McAlonis-Downes, M.; Vetto, A.P.; Lee, S.K.; Tseng, E.; Cleveland, D.W. Enhancing mitochondrial calcium buffering capacity reduces aggregation of misfolded SOD1 and motor neuron cell death without extending survival in mouse models of inherited amyotrophic lateral sclerosis. J. Neurosci. 2013, 33, 4657-4671.
-
(2013)
J. Neurosci
, vol.33
, pp. 4657-4671
-
-
Parone, P.A.1
da Cruz, S.2
Han, J.S.3
McAlonis-Downes, M.4
Vetto, A.P.5
Lee, S.K.6
Tseng, E.7
Cleveland, D.W.8
-
36
-
-
79954633016
-
Calcium dysregulation, mitochondrial pathology and protein aggregation in a culture model of amyotrophic lateral sclerosis: Mechanistic relationship and differential sensitivity to intervention
-
Tradewell, M.L.; Cooper, L.A.; Minotti, S.; Durham, H.D. Calcium dysregulation, mitochondrial pathology and protein aggregation in a culture model of amyotrophic lateral sclerosis: Mechanistic relationship and differential sensitivity to intervention. Neurobiol. Dis. 2011, 42, 265-275.
-
(2011)
Neurobiol. Dis
, vol.42
, pp. 265-275
-
-
Tradewell, M.L.1
Cooper, L.A.2
Minotti, S.3
Durham, H.D.4
-
37
-
-
84883434936
-
Calcium ions promote superoxide dismutase 1 (SOD1) aggregation into non fibrillar amyloid: A link to toxic effects of calcium overload in amyotrophic lateral sclerosis (ALS)?
-
Leal, S.S.; Cardoso, I.; Valentine, J.S.; Gomes, C.M. Calcium ions promote superoxide dismutase 1 (SOD1) aggregation into non fibrillar amyloid: A link to toxic effects of calcium overload in amyotrophic lateral sclerosis (ALS)? J. Biol. Chem. 2013, 288, 25219-25228.
-
(2013)
J. Biol. Chem
, vol.288
, pp. 25219-25228
-
-
Leal, S.S.1
Cardoso, I.2
Valentine, J.S.3
Gomes, C.M.4
-
38
-
-
53049109088
-
Complete loss of post-translational modifications triggers fibrillar aggregation of SOD1 in the familial form of amyotrophic lateral sclerosis
-
Furukawa, Y.; Kaneko, K.; Yamanaka, K.; O'Halloran, T.V.; Nukina, N. Complete loss of post-translational modifications triggers fibrillar aggregation of SOD1 in the familial form of amyotrophic lateral sclerosis. J. Biol. Chem. 2008, 283, 24167-24176.
-
(2008)
J. Biol. Chem
, vol.283
, pp. 24167-24176
-
-
Furukawa, Y.1
Kaneko, K.2
Yamanaka, K.3
O'Halloran, T.V.4
Nukina, N.5
-
39
-
-
20444504724
-
Amyotrophic lateral sclerosis mutations have the greatest destabilizing effect on the apo-and reduced form of SOD1, leading to unfolding and oxidative aggregation
-
Furukawa, Y.; O'Halloran, T.V. Amyotrophic lateral sclerosis mutations have the greatest destabilizing effect on the apo-and reduced form of SOD1, leading to unfolding and oxidative aggregation. J. Biol. Chem. 2005, 280, 17266-17274.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 17266-17274
-
-
Furukawa, Y.1
O'Halloran, T.V.2
-
40
-
-
31544467869
-
Disulphide-reduced superoxide dismutase-1 in CNS of transgenic amyotrophic lateral sclerosis models
-
Jonsson, P.A.; Graffmo, K.S.; Andersen, P.M.; Brannstrom, T.; Lindberg, M.; Oliveberg, M.; Marklund, S.L. Disulphide-reduced superoxide dismutase-1 in CNS of transgenic amyotrophic lateral sclerosis models. Brain 2006, 129, 451-464.
-
(2006)
Brain
, vol.129
, pp. 451-464
-
-
Jonsson, P.A.1
Graffmo, K.S.2
Andersen, P.M.3
Brannstrom, T.4
Lindberg, M.5
Oliveberg, M.6
Marklund, S.L.7
-
41
-
-
78951472170
-
Copper and zinc metallation status of copper-zinc superoxide dismutase from amyotrophic lateral sclerosis transgenic mice
-
Lelie, H.L.; Liba, A.; Bourassa, M.W.; Chattopadhyay, M.; Chan, P.K.; Gralla, E.B.; Miller, L.M.; Borchelt, D.R.; Valentine, J.S.; Whitelegge, J.P. Copper and zinc metallation status of copper-zinc superoxide dismutase from amyotrophic lateral sclerosis transgenic mice. J. Biol. Chem. 2011, 286, 2795-2806.
-
(2011)
J. Biol. Chem
, vol.286
, pp. 2795-2806
-
-
Lelie, H.L.1
Liba, A.2
Bourassa, M.W.3
Chattopadhyay, M.4
Chan, P.K.5
Gralla, E.B.6
Miller, L.M.7
Borchelt, D.R.8
Valentine, J.S.9
Whitelegge, J.P.10
-
42
-
-
84876148784
-
Hmdb 3.0-The human metabolome database in 2013
-
Wishart, D.S.; Jewison, T.; Guo, A.C.; Wilson, M.; Knox, C.; Liu, Y.; Djoumbou, Y.; Mandal, R.; Aziat, F.; Dong, E.; et al. Hmdb 3.0-The human metabolome database in 2013. Nucleic Acids Res. 2013, 41, D801-D807.
-
(2013)
Nucleic Acids Res
, vol.41
-
-
Wishart, D.S.1
Jewison, T.2
Guo, A.C.3
Wilson, M.4
Knox, C.5
Liu, Y.6
Djoumbou, Y.7
Mandal, R.8
Aziat, F.9
Dong, E.10
-
43
-
-
33749365298
-
A molecular mechanism for osmolyte-induced protein stability
-
Street, T.O.; Bolen, D.W.; Rose, G.D. A molecular mechanism for osmolyte-induced protein stability. Proc. Natl. Acad. Sci. USA 2006, 103, 13997-14002.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 13997-14002
-
-
Street, T.O.1
Bolen, D.W.2
Rose, G.D.3
-
44
-
-
71749117373
-
Metal-free superoxide dismutase-1 and three different amyotrophic lateral sclerosis variants share a similar partially unfolded beta-barrel at physiological temperature
-
Durazo, A.; Shaw, B.F.; Chattopadhyay, M.; Faull, K.F.; Nersissian, A.M.; Valentine, J.S.; Whitelegge, J.P. Metal-free superoxide dismutase-1 and three different amyotrophic lateral sclerosis variants share a similar partially unfolded beta-barrel at physiological temperature. J. Biol. Chem. 2009, 284, 34382-34389.
-
(2009)
J. Biol. Chem
, vol.284
, pp. 34382-34389
-
-
Durazo, A.1
Shaw, B.F.2
Chattopadhyay, M.3
Faull, K.F.4
Nersissian, A.M.5
Valentine, J.S.6
Whitelegge, J.P.7
-
45
-
-
44649133131
-
Extrinsic fluorescent dyes as tools for protein characterization
-
Hawe, A.; Sutter, M.; Jiskoot, W. Extrinsic fluorescent dyes as tools for protein characterization. Pharm. Res. 2008, 25, 1487-1499.
-
(2008)
Pharm. Res
, vol.25
, pp. 1487-1499
-
-
Hawe, A.1
Sutter, M.2
Jiskoot, W.3
-
46
-
-
23844471242
-
Aberrantly increased hydrophobicity shared by mutants of Cu, Zn-superoxide dismutase in familial amyotrophic lateral sclerosis
-
Tiwari, A.; Xu, Z.; Hayward, L.J. Aberrantly increased hydrophobicity shared by mutants of Cu, Zn-superoxide dismutase in familial amyotrophic lateral sclerosis. J. Biol. Chem. 2005, 280, 29771-29779.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 29771-29779
-
-
Tiwari, A.1
Xu, Z.2
Hayward, L.J.3
-
47
-
-
77954757268
-
Exposure of hydrophobic surfaces initiates aggregation of diverse ALS-causing superoxide dismutase-1 mutants
-
Munch, C.; Bertolotti, A. Exposure of hydrophobic surfaces initiates aggregation of diverse ALS-causing superoxide dismutase-1 mutants. J. Mol. Biol. 2010, 399, 512-525.
-
(2010)
J. Mol. Biol
, vol.399
, pp. 512-525
-
-
Munch, C.1
Bertolotti, A.2
-
48
-
-
0032849874
-
Quantification of beta-sheet amyloid fibril structures with thioflavin T
-
LeVine, H., 3rd. Quantification of beta-sheet amyloid fibril structures with thioflavin T. Methods Enzymol. 1999, 309, 274-284.
-
(1999)
Methods Enzymol
, vol.309
, pp. 274-284
-
-
LeVine III, H.1
-
49
-
-
0027502784
-
Thioflavine T interaction with synthetic Alzheimer's disease beta-amyloid peptides: Detection of amyloid aggregation in solution
-
LeVine, H., 3rd. Thioflavine T interaction with synthetic Alzheimer's disease beta-amyloid peptides: Detection of amyloid aggregation in solution. Protein Sci. 1993, 2, 404-410.
-
(1993)
Protein Sci
, vol.2
, pp. 404-410
-
-
LeVine III, H.1
-
50
-
-
77952320068
-
Molecular mechanism of thioflavin-T binding to amyloid fibrils
-
Biancalana, M.; Koide, S. Molecular mechanism of thioflavin-T binding to amyloid fibrils. Biochim. Biophys. Acta 2010, 1804, 1405-1412.
-
(2010)
Biochim. Biophys. Acta
, vol.1804
, pp. 1405-1412
-
-
Biancalana, M.1
Koide, S.2
-
51
-
-
57149145222
-
The ratio of monomeric to aggregated forms of abeta40 and abeta42 is an important determinant of amyloid-beta aggregation, fibrillogenesis, and toxicity
-
Jan, A.; Gokce, O.; Luthi-Carter, R.; Lashuel, H.A. The ratio of monomeric to aggregated forms of abeta40 and abeta42 is an important determinant of amyloid-beta aggregation, fibrillogenesis, and toxicity. J. Biol. Chem. 2008, 283, 28176-28189.
-
(2008)
J. Biol. Chem
, vol.283
, pp. 28176-28189
-
-
Jan, A.1
Gokce, O.2
Luthi-Carter, R.3
Lashuel, H.A.4
-
52
-
-
37349075778
-
Congo red and thioflavin-t analogs detect abeta oligomers
-
Maezawa, I.; Hong, H.S.; Liu, R.; Wu, C.Y.; Cheng, R.H.; Kung, M.P.; Kung, H.F.; Lam, K.S.; Oddo, S.; Laferla, F.M.; et al. Congo red and thioflavin-t analogs detect abeta oligomers. J. Neurochem. 2008, 104, 457-468.
-
(2008)
J. Neurochem
, vol.104
, pp. 457-468
-
-
Maezawa, I.1
Hong, H.S.2
Liu, R.3
Wu, C.Y.4
Cheng, R.H.5
Kung, M.P.6
Kung, H.F.7
Lam, K.S.8
Oddo, S.9
Laferla, F.M.10
-
53
-
-
28944433479
-
The changing face of glucagon fibrillation: Structural polymorphism and conformational imprinting
-
Pedersen, J.S.; Dikov, D.; Flink, J.L.; Hjuler, H.A.; Christiansen, G.; Otzen, D.E. The changing face of glucagon fibrillation: Structural polymorphism and conformational imprinting. J. Mol. Biol. 2006, 355, 501-523.
-
(2006)
J. Mol. Biol
, vol.355
, pp. 501-523
-
-
Pedersen, J.S.1
Dikov, D.2
Flink, J.L.3
Hjuler, H.A.4
Christiansen, G.5
Otzen, D.E.6
-
54
-
-
34547120448
-
Amyotrophic lateral sclerosis-associated copper/zinc superoxide dismutase mutations preferentially reduce the repulsive charge of the proteins
-
Sandelin, E.; Nordlund, A.; Andersen, P.M.; Marklund, S.S.; Oliveberg, M. Amyotrophic lateral sclerosis-associated copper/zinc superoxide dismutase mutations preferentially reduce the repulsive charge of the proteins. J. Biol. Chem. 2007, 282, 21230-21236.
-
(2007)
J. Biol. Chem
, vol.282
, pp. 21230-21236
-
-
Sandelin, E.1
Nordlund, A.2
Andersen, P.M.3
Marklund, S.S.4
Oliveberg, M.5
-
55
-
-
43149117084
-
Inhibition of protein aggregation: Supramolecular assemblies of arginine hold the key
-
Das, U.; Hariprasad, G.; Ethayathulla, A.S.; Manral, P.; Das, T.K.; Pasha, S.; Mann, A.; Ganguli, M.; Verma, A.K.; Bhat, R.; et al. Inhibition of protein aggregation: Supramolecular assemblies of arginine hold the key. PLoS One 2007, 2, e1176.
-
(2007)
PLoS One
, vol.2
-
-
Das, U.1
Hariprasad, G.2
Ethayathulla, A.S.3
Manral, P.4
Das, T.K.5
Pasha, S.6
Mann, A.7
Ganguli, M.8
Verma, A.K.9
Bhat, R.10
-
56
-
-
24944581330
-
Review: Why is arginine effective in suppressing aggregation?
-
Tsumoto, K.; Ejima, D.; Kita, Y.; Arakawa, T. Review: Why is arginine effective in suppressing aggregation? Protein Pept. Lett. 2005, 12, 613-619.
-
(2005)
Protein Pept. Lett
, vol.12
, pp. 613-619
-
-
Tsumoto, K.1
Ejima, D.2
Kita, Y.3
Arakawa, T.4
-
57
-
-
79954426524
-
Effects of arginine on heat-induced aggregation of concentrated protein solutions
-
Shah, D.; Shaikh, A.R.; Peng, X.; Rajagopalan, R. Effects of arginine on heat-induced aggregation of concentrated protein solutions. Biotechnol. Prog. 2011, 27, 513-520.
-
(2011)
Biotechnol. Prog
, vol.27
, pp. 513-520
-
-
Shah, D.1
Shaikh, A.R.2
Peng, X.3
Rajagopalan, R.4
-
58
-
-
57749100302
-
Initiation and elongation in fibrillation of ALS-linked superoxide dismutase
-
Chattopadhyay, M.; Durazo, A.; Sohn, S.H.; Strong, C.D.; Gralla, E.B.; Whitelegge, J.P.; Valentine, J.S. Initiation and elongation in fibrillation of ALS-linked superoxide dismutase. Proc. Natl. Acad. Sci. USA 2008, 105, 18663-18668.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 18663-18668
-
-
Chattopadhyay, M.1
Durazo, A.2
Sohn, S.H.3
Strong, C.D.4
Gralla, E.B.5
Whitelegge, J.P.6
Valentine, J.S.7
-
59
-
-
63449092530
-
Loss of metal ions, disulfide reduction and mutations related to familial als promote formation of amyloid-like aggregates from superoxide dismutase
-
Oztug Durer, Z.A.; Cohlberg, J.A.; Dinh, P.; Padua, S.; Ehrenclou, K.; Downes, S.; Tan, J.K.; Nakano, Y.; Bowman, C.J.; Hoskins, J.L.; et al. Loss of metal ions, disulfide reduction and mutations related to familial als promote formation of amyloid-like aggregates from superoxide dismutase. PLoS One 2009, 4, e5004.
-
(2009)
PLoS One
, vol.4
-
-
Oztug Durer, Z.A.1
Cohlberg, J.A.2
Dinh, P.3
Padua, S.4
Ehrenclou, K.5
Downes, S.6
Tan, J.K.7
Nakano, Y.8
Bowman, C.J.9
Hoskins, J.L.10
-
60
-
-
77953291167
-
Critical evaluation of nanoparticle tracking analysis (NTA) by nanosight for the measurement of nanoparticles and protein aggregates
-
Filipe, V.; Hawe, A.; Jiskoot, W. Critical evaluation of nanoparticle tracking analysis (NTA) by nanosight for the measurement of nanoparticles and protein aggregates. Pharm. Res. 2010, 27, 796-810.
-
(2010)
Pharm. Res
, vol.27
, pp. 796-810
-
-
Filipe, V.1
Hawe, A.2
Jiskoot, W.3
-
61
-
-
0038442784
-
Amyloid-like filaments and water-filled nanotubes formed by SOD1 mutant proteins linked to familial ALS
-
Elam, J.; Taylor, A.; Strange, R.; Antonyuk, S.; Doucette, P.; Rodriguez, J.; Hasnain, S.; Hayward, L.; Valentine, J.; Yeates, T.; et al. Amyloid-like filaments and water-filled nanotubes formed by SOD1 mutant proteins linked to familial ALS. Nat. Struct. Biol. 2003, 10, 461-467.
-
(2003)
Nat. Struct. Biol
, vol.10
, pp. 461-467
-
-
Elam, J.1
Taylor, A.2
Strange, R.3
Antonyuk, S.4
Doucette, P.5
Rodriguez, J.6
Hasnain, S.7
Hayward, L.8
Valentine, J.9
Yeates, T.10
-
62
-
-
84879734853
-
Structural similarity of wild-type and ALS-mutant superoxide dismutase-1 fibrils using limited proteolysis and atomic force microscopy
-
Chan, P.K.; Chattopadhyay, M.; Sharma, S.; Souda, P.; Gralla, E.B.; Borchelt, D.R.; Whitelegge, J.P.; Valentine, J.S. Structural similarity of wild-type and ALS-mutant superoxide dismutase-1 fibrils using limited proteolysis and atomic force microscopy. Proc. Natl. Acad. Sci. USA 2013, 110, 10934-10939.
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 10934-10939
-
-
Chan, P.K.1
Chattopadhyay, M.2
Sharma, S.3
Souda, P.4
Gralla, E.B.5
Borchelt, D.R.6
Whitelegge, J.P.7
Valentine, J.S.8
-
63
-
-
4444291348
-
Coexpression of yeast copper chaperone (YCCS) and Cu/Zn-superoxide dismutases in Escherichia coli yields protein with high copper contents
-
Ahl, I.M.; Lindberg, M.J.; Tibell, L.A. Coexpression of yeast copper chaperone (YCCS) and Cu/Zn-superoxide dismutases in Escherichia coli yields protein with high copper contents. Protein Expression Purif. 2004, 37, 311-319.
-
(2004)
Protein Expression Purif
, vol.37
, pp. 311-319
-
-
Ahl, I.M.1
Lindberg, M.J.2
Tibell, L.A.3
-
64
-
-
34247505040
-
Binding of a single zinc ion to one subunit of copper-zinc superoxide dismutase apoprotein substantially influences the structure and stability of the entire homodimeric protein
-
Potter, S.Z.; Zhu, H.; Shaw, B.F.; Rodriguez, J.A.; Doucette, P.A.; Sohn, S.H.; Durazo, A.; Faull, K.F.; Gralla, E.B.; Nersissian, A.M.; et al. Binding of a single zinc ion to one subunit of copper-zinc superoxide dismutase apoprotein substantially influences the structure and stability of the entire homodimeric protein. J. Am. Chem. Soc. 2007, 129, 4575-4583.
-
(2007)
J. Am. Chem. Soc
, vol.129
, pp. 4575-4583
-
-
Potter, S.Z.1
Zhu, H.2
Shaw, B.F.3
Rodriguez, J.A.4
Doucette, P.A.5
Sohn, S.H.6
Durazo, A.7
Faull, K.F.8
Gralla, E.B.9
Nersissian, A.M.10
-
65
-
-
72049122126
-
A spectrophotometric method for the determination of zinc, copper, and cobalt ions in metalloproteins using zincon
-
Sabel, C.E.; Neureuther, J.M.; Siemann, S. A spectrophotometric method for the determination of zinc, copper, and cobalt ions in metalloproteins using zincon. Anal. Biochem. 2010, 397, 218-226.
-
(2010)
Anal. Biochem
, vol.397
, pp. 218-226
-
-
Sabel, C.E.1
Neureuther, J.M.2
Siemann, S.3
|