-
1
-
-
65649129982
-
Bile acids: Chemistry, physiology, and pathophysiology
-
Monte, M.J., Marin, J.J., Antelo, A. & Vazquez-tato, J. Bile acids: chemistry, physiology, and pathophysiology. World J. Gastroenterol. 15, 804-816 (2009)
-
(2009)
World J. Gastroenterol.
, vol.15
, pp. 804-816
-
-
Monte, M.J.1
Marin, J.J.2
Antelo, A.3
Vazquez-Tato, J.4
-
2
-
-
79960608008
-
Profle of serum bile acids in noncholestatic volunteers: Gender-related diferences in response to fenofbrate
-
Trottier, J., Caron, P., Straka, R.J. & Barbier, O. Profle of serum bile acids in noncholestatic volunteers: gender-related diferences in response to fenofbrate. Clin. Pharmacol. Ther. 90, 279-286 (2011).
-
(2011)
Clin. Pharmacol. Ther.
, vol.90
, pp. 279-286
-
-
Trottier, J.1
Caron, P.2
Straka, R.J.3
Barbier, O.4
-
4
-
-
77951561501
-
Nuclear receptor regulation of the adaptive response of bile acid transporters in cholestasis
-
Wagner, M., Zollner, G. & trauner, M. Nuclear receptor regulation of the adaptive response of bile acid transporters in cholestasis. Semin. Liver Dis. 30, 160-177 (2010).
-
(2010)
Semin. Liver Dis.
, vol.30
, pp. 160-177
-
-
Wagner, M.1
Zollner, G.2
Trauner, M.3
-
5
-
-
77954095142
-
Pharmacotherapy of cholestatic liver diseases
-
Paumgartner, G. Pharmacotherapy of cholestatic liver diseases. J. Dig. Dis. 11, 119-125 (2010)
-
(2010)
J. Dig. Dis.
, vol.11
, pp. 119-125
-
-
Paumgartner, G.1
-
6
-
-
33745797036
-
Coordinate regulation of hepatic bile acid oxidation and conjugation by nuclear receptors
-
DOI 10.1021/mp060020t
-
Trottier, J., Milkiewicz, P., Kaeding, J., Verreault, M. & Barbier, O. Coordinate regulation of hepatic bile acid oxidation and conjugation by nuclear receptors. Mol. Pharm. 3, 212-222 (2006). (Pubitemid 44021429)
-
(2006)
Molecular Pharmaceutics
, vol.3
, Issue.3
, pp. 212-222
-
-
Trottier, J.1
Milkiewicz, P.2
Kaeding, J.3
Verreault, M.4
Barbier, O.5
-
7
-
-
84857635070
-
Primary sclerosing cholangitis: Is any treatment worthwhile?
-
Barnabas, A. & Chapman, R.W. Primary sclerosing cholangitis: is any treatment worthwhile? Curr. Gastroenterol. Rep. 14, 17-24 (2012).
-
(2012)
Curr. Gastroenterol. Rep.
, vol.14
, pp. 17-24
-
-
Barnabas, A.1
Chapman, R.W.2
-
8
-
-
1842482944
-
Fenofibrate for patients with asymptomatic primary biliary cirrhosis
-
Dohmen, K., Mizuta, t., Nakamuta, M., Shimohashi, N., Ishibashi, H. & Yamamoto, K. Fenofbrate for patients with asymptomatic primary biliary cirrhosis. World J. Gastroenterol. 10, 894-898 (2004). (Pubitemid 38418369)
-
(2004)
World Journal of Gastroenterology
, vol.10
, Issue.6
, pp. 894-898
-
-
Dohmen, K.1
Mizuta, T.2
Nakamuta, M.3
Shimohashi, N.4
Ishibashi, H.5
Yamamoto, K.6
-
9
-
-
43049149045
-
The efficacy of ursodeoxycholic acid and bezafibrate combination therapy for primary biliary cirrhosis: A prospective, multicenter study
-
DOI 10.1111/j.1872-034X.2007.00305.x
-
Iwasaki, S. et al.; Study Group of Intractable Liver Diseases for Research on a Specifc Disease, Health Science Research Grant, Ministry of Health, Labour and Welfare of Japan. The efcacy of ursodeoxycholic acid and bezafbrate combination therapy for primary biliary cirrhosis: a prospective, multicenter study. Hepatol. Res. 38, 557-564 (2008). (Pubitemid 351622281)
-
(2008)
Hepatology Research
, vol.38
, Issue.6
, pp. 557-564
-
-
Iwasaki, S.1
Ohira, H.2
Nishiguchi, S.3
Zeniya, M.4
Kaneko, S.5
Onji, M.6
Ishibashi, H.7
Sakaida, I.8
Kuriyama, S.9
Ichida, T.10
Onishi, S.11
Toda, G.12
Tomita, E.13
Shibata, M.14
Watanabe, Y.15
Iwasaki., Y.16
Hirohara, J.17
Nakamura, K.18
Kiyosawa, K.19
Suzuki, K.20
Yasumura, S.21
more..
-
10
-
-
0033989267
-
Combination therapy of bezafibrate and ursodeoxycholic acid in primary biliary cirrhosis: A preliminary study [15]
-
DOI 10.1016/S0002-9270(99)00726-1
-
Nakai, S., Masaki, t., Kurokohchi, K., Deguchi, A. & Nishioka, M. Combination therapy of bezafbrate and ursodeoxycholic acid in primary biliary cirrhosis: a preliminary study. Am. J. Gastroenterol. 95, 326-327 (2000). (Pubitemid 30041596)
-
(2000)
American Journal of Gastroenterology
, vol.95
, Issue.1
, pp. 326-327
-
-
Nakai, S.1
Masaki, T.2
Kurokohchi, K.3
Deguchi, A.4
Nishioka, M.5
-
11
-
-
0036678375
-
Fenofbrate treatment in patients with primary biliary cirrhosis
-
Ohira, H., Sato, Y., Ueno, t. & Sata, M. Fenofbrate treatment in patients with primary biliary cirrhosis. Am. J. Gastroenterol. 97, 2147-2149 (2002).
-
(2002)
Am. J. Gastroenterol.
, vol.97
, pp. 2147-2149
-
-
Ohira, H.1
Sato, Y.2
Ueno, T.3
Sata, M.4
-
12
-
-
78650260680
-
Pilot study: Fenofbrate for patients with primary biliary cirrhosis and an incomplete response to ursodeoxycholic acid
-
Levy, C. et al. Pilot study: fenofbrate for patients with primary biliary cirrhosis and an incomplete response to ursodeoxycholic acid. Aliment. Pharmacol. Ther. 33, 235-242 (2011).
-
(2011)
Aliment. Pharmacol. Ther.
, vol.33
, pp. 235-242
-
-
Levy, C.1
-
13
-
-
79960590369
-
Fenofbrate improves liver tests in primary sclerosing cholangitis with incomplete biochemical response to ursodeoxycholic acid
-
Boston, MA; 29 October-2 November 2010)
-
Chazouilleres, O., Corpechot, C., Gaouar, F., Poupon, R. Fenofbrate improves liver tests in primary sclerosing cholangitis with incomplete biochemical response to ursodeoxycholic acid. 61st Annual Meeting of the American Association for the Study of Liver Diseases (Boston, MA; 29 October-2 November 2010) 488A.
-
61st Annual Meeting of the American Association for the Study of Liver Diseases
-
-
Chazouilleres, O.1
Corpechot, C.2
Gaouar, F.3
Poupon, R.4
-
14
-
-
50649089597
-
Fibrates and future PPARalpha agonists in the treatment of cardiovascular disease
-
Staels, B., Maes, M. & Zambon, A. Fibrates and future PPARalpha agonists in the treatment of cardiovascular disease. Nat. Clin. Pract. Cardiovasc. Med. 5, 542-553 (2008).
-
(2008)
Nat. Clin. Pract. Cardiovasc. Med.
, vol.5
, pp. 542-553
-
-
Staels, B.1
Maes, M.2
Zambon, A.3
-
15
-
-
67349247085
-
Lipid-activated transcription factors control bile acid glucuronidation
-
Barbier, O., trottier, J., Kaeding, J., Caron, P. & Verreault, M. Lipid-activated transcription factors control bile acid glucuronidation. Mol. Cell. Biochem. 326, 3-8 (2009).
-
(2009)
Mol. Cell. Biochem.
, vol.326
, pp. 3-8
-
-
Barbier, O.1
Trottier, J.2
Kaeding, J.3
Caron, P.4
Verreault, M.5
-
16
-
-
0042858402
-
Peroxisome proliferator-activated receptor α induces hepatic expression of the human bile acid glucuronidating UDP-glucuronosyltransferase 2B4 enzyme
-
DOI 10.1074/jbc.M305361200
-
Barbier, O., Duran-Sandoval, D., Pineda-torra, I., Kosykh, V., Fruchart, J.C. & Staels, B. Peroxisome proliferator-activated receptor alpha induces hepatic expression of the human bile acid glucuronidating UDP- glucuronosyltransferase 2B4 enzyme. J. Biol. Chem. 278, 32852-32860 (2003). (Pubitemid 37055727)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.35
, pp. 32852-32860
-
-
Barbier, O.1
Duran-Sandoval, D.2
Pineda-Torra, I.3
Kosykh, V.4
Fruchart, J.-C.5
Staels, B.6
-
17
-
-
33751007567
-
Human UDP-glucuronosyltransferase (UGT)1A3 enzyme conjugates chenodeoxycholic acid in the liver
-
DOI 10.1002/hep.21362
-
Trottier, J. et al. Human UDP-glucuronosyltransferase (UGt)1A3 enzyme conjugates chenodeoxycholic acid in the liver. Hepatology 44, 1158-1170 (2006). (Pubitemid 44748367)
-
(2006)
Hepatology
, vol.44
, Issue.5
, pp. 1158-1170
-
-
Trottier, J.1
Verreault, M.2
Grepper, S.3
Monte, D.4
Belanger, J.5
Kaeding, J.6
Caron, P.7
Inaba, T.T.8
Barbier, O.9
-
18
-
-
33847421803
-
Expression of the human UGt1 locus in transgenic mice by 4-chloro-6-(2, 3-xylidino)-2-pyrimidinylthioacetic acid (WY-14643) and implications on drug metabolism through peroxisome proliferator-activated receptor alpha activation
-
Senekeo-Efenberger, K. et al. Expression of the human UGt1 locus in transgenic mice by 4-chloro-6-(2, 3-xylidino)-2-pyrimidinylthioacetic acid (WY-14643) and implications on drug metabolism through peroxisome proliferator-activated receptor alpha activation. Drug Metab. Dispos. 35, 419-427 (2007).
-
(2007)
Drug Metab. Dispos.
, vol.35
, pp. 419-427
-
-
Senekeo-Efenberger, K.1
-
19
-
-
0037251316
-
Sequence variations in the UDP - Glucuronosyltransferase 2B7 (UGT2B7) gene: Identification of 10 novel single nucleotide polymorphisms (SNPs) and analysis of their relevance to morphine glucoronidation in cancer patients
-
DOI 10.1038/sj.tpj.6500139
-
Holthe, M. et al. Sequence variations in the UDP-glucuronosyltransferase 2B7 (UGt2B7) gene: identifcation of 10 novel single nucleotide polymorphisms (SNPs) and analysis of their relevance to morphine glucuronidation in cancer patients. Pharmacogenomics J. 3, 17-26 (2003). (Pubitemid 36432463)
-
(2003)
Pharmacogenomics Journal
, vol.3
, Issue.1
, pp. 17-26
-
-
Holthe, M.1
Rakvag, T.N.2
Klepstad, P.3
Idle, J.R.4
Kaasa, S.5
Krokan, H.E.6
Skorpen, F.7
-
20
-
-
0034118356
-
85Y)
-
Lampe, J.W., Bigler, J., Bush, A.C. & Potter, J.D. Prevalence of polymorphisms in the human UDP-glucuronosyltransferase 2B family: UGt2B4(D458E), UGt2B7(H268Y), and UGt2B15(D85Y). Cancer Epidemiol. Biomarkers Prev. 9, 329-333 (2000). (Pubitemid 30165447)
-
(2000)
Cancer Epidemiology Biomarkers and Prevention
, vol.9
, Issue.3
, pp. 329-333
-
-
Lampe, J.W.1
Bigler, J.2
Bush, A.C.3
Potter, J.D.4
-
21
-
-
55749107288
-
Single nucleotide polymorphism discovery and functional assessment of variation in the UDP-glucuronosyltransferase 2B7 gene
-
Innocenti, F. et al. Single nucleotide polymorphism discovery and functional assessment of variation in the UDP-glucuronosyltransferase 2B7 gene. Pharmacogenet. Genomics 18, 683-697 (2008).
-
(2008)
Pharmacogenet. Genomics
, vol.18
, pp. 683-697
-
-
Innocenti, F.1
-
22
-
-
1942424750
-
Six novel UDP-glucuronosyltransferase (UGT1A3) polymorphisms with varying activity
-
DOI 10.1007/s10038-003-0119-y
-
Iwai, M., Maruo, Y., Ito, M., Yamamoto, K., Sato, H. & takeuchi, Y. Six novel UDP-glucuronosyltransferase (UGt1A3) polymorphisms with varying activity. J. Hum. Genet. 49, 123-128 (2004). (Pubitemid 38506725)
-
(2004)
Journal of Human Genetics
, vol.49
, Issue.3
, pp. 123-128
-
-
Iwai, M.1
Maruo, Y.2
Ito, M.3
Yamamoto, K.4
Sato, H.5
Takeuchi, Y.6
-
23
-
-
76149117207
-
Associations between polymorphisms in glucuronidation and sulfation enzymes and mammographic breast density in premenopausal women in the United States
-
Yong, M. et al. Associations between polymorphisms in glucuronidation and sulfation enzymes and mammographic breast density in premenopausal women in the United States. Cancer Epidemiol. Biomarkers Prev. 19, 537-546 (2010).
-
(2010)
Cancer Epidemiol. Biomarkers Prev.
, vol.19
, pp. 537-546
-
-
Yong, M.1
-
24
-
-
34250214170
-
A pharmacogenomics study of the human estrogen glucuronosyltransferase UGT1A3
-
DOI 10.1097/FPC.0b013e32806d87a4, PII 0121301120070700000003
-
Caillier, B. et al. A pharmacogenomics study of the human estrogen glucuronosyltransferase UGt1A3. Pharmacogenet. Genomics 17, 481-495 (2007). (Pubitemid 46905215)
-
(2007)
Pharmacogenetics and Genomics
, vol.17
, Issue.7
, pp. 481-495
-
-
Caillier, B.1
Lepine, J.2
Tojcic, J.3
Menard, V.4
Perusse, L.5
Belanger, A.6
Barbier, O.7
Guillemette, C.8
-
25
-
-
0031894377
-
The glucuronidation of opioids, other xenobiotics, and androgens by human UGT2B7Y(268) and UGT2B7H(268)
-
Cofman, B.L., King, C.D., Rios, G.R. & tephly, t.R. The glucuronidation of opioids, other xenobiotics, and androgens by human UGt2B7Y(268) and UGt2B7H(268). Drug Metab. Dispos. 26, 73-77 (1998). (Pubitemid 28071328)
-
(1998)
Drug Metabolism and Disposition
, vol.26
, Issue.1
, pp. 73-77
-
-
Coffman, B.L.1
King, C.D.2
Rios, G.R.3
Tephly, T.R.4
-
26
-
-
79959453365
-
In vitro investigation of human UDP-glucuronosyltransferase isoforms responsible for tacrolimus glucuronidation: Predominant contribution of UGt1A4
-
Laverdière, I., Caron, P., Harvey, M., Lévesque, É. & Guillemette, C. In vitro investigation of human UDP- glucuronosyltransferase isoforms responsible for tacrolimus glucuronidation: predominant contribution of UGt1A4. Drug Metab. Dispos. 39, 1127-1130 (2011).
-
(2011)
Drug Metab. Dispos.
, vol.39
, pp. 1127-1130
-
-
Laverdière, I.1
Caron, P.2
Harvey, M.3
Lévesque, É.4
Guillemette, C.5
-
27
-
-
33747040567
-
The liver X-receptor alpha controls hepatic expression of the human bile acid-glucuronidating UGT1A3 enzyme in human cells and transgenic mice
-
DOI 10.1002/hep.21259
-
Verreault, M. et al. The liver X-receptor alpha controls hepatic expression of the human bile acid-glucuronidating UGt1A3 enzyme in human cells and transgenic mice. Hepatology 44, 368-378 (2006). (Pubitemid 44214876)
-
(2006)
Hepatology
, vol.44
, Issue.2
, pp. 368-378
-
-
Verreault, M.1
Senekeo-Effenberger, K.2
Trottier, J.3
Bonzo, J.A.4
Belanger, J.5
Kaeding, J.6
Staels, B.7
Caron, P.8
Tukey, R.H.9
Barbier, O.10
-
28
-
-
0027209892
-
Lithocholate-3-O-glucuronide-induced cholestasis. A study with congenital hyperbilirubinemic rats and effects of ursodeoxycholate conjugates
-
Takikawa, H., Minagawa, K., Sano, N. & Yamanaka M. Lithocholate-3-O-glucuronide-induced cholestasis. A study with congenital hyperbilirubinemic rats and efects of ursodeoxycholate conjugates. Dig. Dis. Sci. 38, 1543-1548 (1993). (Pubitemid 23266640)
-
(1993)
Digestive Diseases and Sciences
, vol.38
, Issue.8
, pp. 1543-1548
-
-
Takikawa, H.1
Minagawa, K.2
Sano, N.3
Yamanaka, M.4
-
29
-
-
0032838879
-
Differential glucuronidation of bile acids, androgens and estrogens by human UGT1A3 and 2B7
-
DOI 10.1016/S0960-0760(99)00088-6, PII S0960076099000886
-
Gall, W.E. et al. Diferential glucuronidation of bile acids, androgens and estrogens by human UGt1A3 and 2B7. J. Steroid Biochem. Mol. Biol. 70, 101-108 (1999). (Pubitemid 29406026)
-
(1999)
Journal of Steroid Biochemistry and Molecular Biology
, vol.70
, Issue.1-3
, pp. 101-108
-
-
Gall, W.E.1
Zawada, G.2
Mojarrabi, B.3
Tephly, T.R.4
Green, M.D.5
Coffman, B.L.6
Mackenzie, P.I.7
Radominska-Pandya, A.8
-
30
-
-
33745795303
-
Enzymatic production of bile acid glucuronides used as analytical standards for liquid chromatography-mass spectrometry analyses
-
DOI 10.1021/mp060021l
-
Caron, P., trottier, J., Verreault, M., Bélanger, J., Kaeding, J. & Barbier, O. Enzymatic production of bile Acid glucuronides used as analytical standards for liquid chromatography-mass spectrometry analyses. Mol. Pharm. 3, 293-302 (2006). (Pubitemid 44021435)
-
(2006)
Molecular Pharmaceutics
, vol.3
, Issue.3
, pp. 293-302
-
-
Caron, P.1
Trottier, J.2
Verreault, M.3
Belanger, J.4
Kaeding, J.5
Barbier, O.6
-
31
-
-
34247331741
-
Why bile acid glucuronidation is a minor pathway for conjugation of endogenous bile acids in man [3]
-
DOI 10.1002/hep.21576
-
Hofmann, A.F. Why bile acid glucuronidation is a minor pathway for conjugation of endogenous bile acids in man. Hepatology 45, 1083-1084; author reply 1084 (2007). (Pubitemid 46631579)
-
(2007)
Hepatology
, vol.45
, Issue.4
, pp. 1083-1084
-
-
Hofmann, A.F.1
-
32
-
-
78649495086
-
Acyl glucuronides: The good, the bad and the ugly
-
Regan, S.L., Maggs, J.L., Hammond, t.G., Lambert, C., Williams, D.P. & Park, B.K. Acyl glucuronides: the good, the bad and the ugly. Biopharm. Drug Dispos. 31, 367-395 (2010).
-
(2010)
Biopharm. Drug Dispos.
, vol.31
, pp. 367-395
-
-
Regan, S.L.1
Maggs, J.L.2
Hammond, T.G.3
Lambert, C.4
Williams, D.P.5
Park, K.B.6
-
33
-
-
0037306174
-
Acyl glucuronide drug metabolites: Toxicological and analytical implications
-
DOI 10.1097/00007691-200302000-00001
-
Shipkova, M., Armstrong, V.W., Oellerich, M. & Wieland, E. Acyl glucuronide drug metabolites: toxicological and analytical implications. Ther. Drug Monit. 25, 1-16 (2003). (Pubitemid 36139819)
-
(2003)
Therapeutic Drug Monitoring
, vol.25
, Issue.1
, pp. 1-16
-
-
Shipkova, M.1
Armstrong, V.W.2
Oellerich, M.3
Wieland, E.4
-
34
-
-
78650736079
-
Plasma stability-dependent circulation of acyl glucuronide metabolites in humans: How circulating metabolite profles of muraglitazar and peliglitazar can lead to misleading risk assessment
-
Zhang, D. et al. Plasma stability-dependent circulation of acyl glucuronide metabolites in humans: how circulating metabolite profles of muraglitazar and peliglitazar can lead to misleading risk assessment. Drug Metab. Dispos. 39, 123-131 (2011).
-
(2011)
Drug Metab. Dispos.
, vol.39
, pp. 123-131
-
-
Zhang, D.1
-
35
-
-
63849241530
-
Mechanism of gender-divergent UDP-glucuronosyltransferase mRNA expression in mouse liver and kidney
-
Buckley, D.B. & Klaassen, C.D. Mechanism of gender-divergent UDP-glucuronosyltransferase mRNA expression in mouse liver and kidney. Drug Metab. Dispos. 37, 834-840 (2009).
-
(2009)
Drug Metab. Dispos.
, vol.37
, pp. 834-840
-
-
Buckley, D.B.1
Klaassen, C.D.2
-
36
-
-
74049083754
-
The human UGt1A3 enzyme conjugates norursodeoxycholic acid into a C23-ester glucuronide in the liver
-
Trottier, J. et al. The human UGt1A3 enzyme conjugates norursodeoxycholic acid into a C23-ester glucuronide in the liver. J. Biol. Chem. 285, 1113-1121 (2010).
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 1113-1121
-
-
Trottier, J.1
-
37
-
-
74549174924
-
Regulation of endobiotics glucuronidation by ligand-activated transcription factors: Physiological function and therapeutic potential
-
Verreault, M. et al. Regulation of endobiotics glucuronidation by ligand-activated transcription factors: physiological function and therapeutic potential. Drug Metab. Rev. 42, 110-122 (2010)
-
(2010)
Drug Metab. Rev.
, vol.42
, pp. 110-122
-
-
Verreault, M.1
-
38
-
-
77949654677
-
Regulation of the human bile acid UDP-glucuronosyltransferase 1A3 by the farnesoid X receptor and bile acids
-
Erichsen, T.J., Aehlen, A., Ehmer, U., Kalthof, S., Manns, M.P. & Strassburg, C.P. Regulation of the human bile acid UDP-glucuronosyltransferase 1A3 by the farnesoid X receptor and bile acids. J. Hepatol. 52, 570-578 (2010).
-
(2010)
J. Hepatol.
, vol.52
, pp. 570-578
-
-
Erichsen, T.J.1
Aehlen, A.2
Ehmer, U.3
Kalthof, S.4
Manns, M.P.5
Strassburg, C.P.6
-
39
-
-
0032812606
-
458): A UDP-glucuronosyltransferase encoded by a polymorphic gene
-
Lévesque, E., Beaulieu, M., Hum, D.W. & Bélanger, A. Characterization and substrate specifcity of UGt2B4 (E458): a UDP-glucuronosyltransferase encoded by a polymorphic gene. Pharmacogenetics 9, 207-216 (1999). (Pubitemid 29359003)
-
(1999)
Pharmacogenetics
, vol.9
, Issue.2
, pp. 207-216
-
-
Levesque, E.1
Beaulieu, M.2
Hum, D.W.3
Belanger, A.4
-
40
-
-
76749156700
-
Extensive splicing of transcripts encoding the bile acid-conjugating enzyme UGt2B4 modulates glucuronidation
-
Lévesque, E. et al. Extensive splicing of transcripts encoding the bile acid-conjugating enzyme UGt2B4 modulates glucuronidation. Pharmacogenet. Genomics 20, 195-210 (2010).
-
(2010)
Pharmacogenet. Genomics
, vol.20
, pp. 195-210
-
-
Lévesque, E.1
-
41
-
-
33645865553
-
Induction of hepatic transporters multidrug resistance-associated proteins (Mrp) 3 and 4 by clofbrate is regulated by peroxisome proliferator-activated receptor alpha
-
Moft, J.S., Aleksunes, L.M., Maher, J.M., Schefer, G.L., Klaassen, C.D. & Manautou, J.E. Induction of hepatic transporters multidrug resistance-associated proteins (Mrp) 3 and 4 by clofbrate is regulated by peroxisome proliferator-activated receptor alpha. J. Pharmacol. Exp. Ther. 317, 537-545 (2006).
-
(2006)
J. Pharmacol. Exp. Ther.
, vol.317
, pp. 537-545
-
-
Moft, J.S.1
Aleksunes, L.M.2
Maher, J.M.3
Schefer, G.L.4
Klaassen, C.D.5
Manautou, J.E.6
-
42
-
-
22344433760
-
Induction of the multidrug resistance-associated protein family of transporters by chemical activators of receptor-mediated pathways in mouse liver
-
DOI 10.1124/dmd.105.003798
-
Maher, J.M., Cheng, X., Slitt, A.L., Dieter, M.Z. & Klaassen, C.D. Induction of the multidrug resistance-associated protein family of transporters by chemical activators of receptor-mediated pathways in mouse liver. Drug Metab. Dispos. 33, 956-962 (2005). (Pubitemid 41002777)
-
(2005)
Drug Metabolism and Disposition
, vol.33
, Issue.7
, pp. 956-962
-
-
Maher, J.M.1
Cheng, X.2
Slitt, A.L.3
Dieter, M.Z.4
Klaassen, C.D.5
-
43
-
-
70349282243
-
Construction of triple-transfected cells [organic anion-transporting polypeptide (OAtP) 1B1/multidrug resistance-associated protein (MRP) 2/MRP3 and OAtP1B1/MRP2/MRP4] for analysis of the sinusoidal function of MRP3 and MRP4
-
Hirouchi, M., Kusuhara, H., Onuki, R., Ogilvie, B.W., Parkinson, A. & Sugiyama, Y. Construction of triple-transfected cells [organic anion-transporting polypeptide (OAtP) 1B1/multidrug resistance-associated protein (MRP) 2/MRP3 and OAtP1B1/MRP2/MRP4] for analysis of the sinusoidal function of MRP3 and MRP4. Drug Metab. Dispos. 37, 2103-2111 (2009).
-
(2009)
Drug Metab. Dispos.
, vol.37
, pp. 2103-2111
-
-
Hirouchi, M.1
Kusuhara, H.2
Onuki, R.3
Ogilvie, B.W.4
Parkinson, A.5
Sugiyama, Y.6
-
44
-
-
77950863027
-
Latest and emerging therapies for primary biliary cirrhosis and primary sclerosing cholangitis
-
Zein, C.O. & Lindor, K.D. Latest and emerging therapies for primary biliary cirrhosis and primary sclerosing cholangitis. Curr. Gastroenterol. Rep. 12, 13-22 (2010).
-
(2010)
Curr. Gastroenterol. Rep.
, vol.12
, pp. 13-22
-
-
Zein, C.O.1
Lindor, K.D.2
-
45
-
-
21844436858
-
Enterohepatic transport of bile salts and genetics of cholestasis
-
DOI 10.1016/j.jhep.2005.03.017, PII S0168827805003077
-
Pauli-Magnus, C., Stieger, B., Meier, Y., Kullak-Ublick, G.A. & Meier, P.J. Enterohepatic transport of bile salts and genetics of cholestasis. J. Hepatol. 43, 342-357 (2005). (Pubitemid 40956889)
-
(2005)
Journal of Hepatology
, vol.43
, Issue.2
, pp. 342-357
-
-
Pauli-Magnus, C.1
Stieger, B.2
Meier, Y.3
Kullak-Ublick, G.A.4
Meier, P.J.5
-
46
-
-
35348900226
-
Fibrate for treatment of primary biliary cirrhosis
-
DOI 10.1111/j.1872-034X.2007.00232.x
-
Iwasaki, S., Akisawa, N., Saibara, t. & Onishi, S. Fibrate for treatment of primary biliary cirrhosis. Hepatol. Res. 37 (suppl. 3), S515-S517 (2007). (Pubitemid 47570668)
-
(2007)
Hepatology Research
, vol.37
, Issue.SUPPL. 3
-
-
Iwasaki, S.1
Akisawa, N.2
Saibara, T.3
Onishi, S.4
-
47
-
-
34249294501
-
Fenofbrate efect on triglyceride and postprandial response of apolipoprotein A5 variants: The GOLDN study
-
Lai, C.Q. et al. Fenofbrate efect on triglyceride and postprandial response of apolipoprotein A5 variants: the GOLDN study. Arterioscler. Thromb. Vasc. Biol. 27, 1417-1425 (2007).
-
(2007)
Arterioscler. Thromb. Vasc. Biol.
, vol.27
, pp. 1417-1425
-
-
Lai, C.Q.1
-
48
-
-
80355130039
-
Modifed annexin V/propidium iodide apoptosis assay for accurate assessment of cell death
-
e-pub 24 April 2011
-
Rieger, A.M., Nelson, K.L., Konowalchuk, J.D. & Barreda, D.R. Modifed annexin V/propidium iodide apoptosis assay for accurate assessment of cell death. J. Vis. Exp. (2011); e-pub 24 April 2011.
-
(2011)
J. Vis. Exp.
-
-
Rieger, A.M.1
Nelson, K.L.2
Konowalchuk, J.D.3
Barreda, D.R.4
-
49
-
-
73949095106
-
A pharmacogenetics study of the human glucuronosyltransferase UGt1A4
-
Benoit-Biancamano, M.O. et al. A pharmacogenetics study of the human glucuronosyltransferase UGt1A4. Pharmacogenet. Genomics 19, 945-954 (2009).
-
(2009)
Pharmacogenet. Genomics
, vol.19
, pp. 945-954
-
-
Benoit-Biancamano, M.O.1
|