The liver X-receptor alpha controls hepatic expression of the human bile acid-glucuronidating UGT1A3 enzyme in human cells and transgenic mice

Hepatology

Volumn 44, Issue 2, 2006, Pages 368-378

  Verreault, Mélanie ^a   Senekeo Effenberger, Kathy ^b   Trottier, Jocelyn ^a   Bonzo, Jessica A ^b   Bélanger, Julie ^a   Kaeding, Jenny ^a   Staels, Bart ^c   Caron, Patrick ^a   Tukey, Robert H ^b   Barbier, Olivier ^a  

^a LAVAL UNIVERSITY   (Canada)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c INSTITUT PASTEUR DE LILLE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BILE ACID; CHENODEOXYCHOLIC ACID; ENZYME; LITHOCHOLIC ACID; LIVER X RECEPTOR ALPHA; MESSENGER RNA; N (2,2,2 TRIFLUOROETHYL) N [4 [2,2,2 TRIFLUORO 1 HYDROXY 1 (TRIFLUOROMETHOXY)ETHYL]PHENYL]BENZENESULFONAMIDE; PROTEIN; PROTEIN PGC 1BETA; SRC 1ALPHA; UGT1A3 ENZYME; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME REGULATION; GEL MOBILITY SHIFT ASSAY; GENE TARGETING; HUMAN; HUMAN CELL; LIVER CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; SITE DIRECTED MUTAGENESIS; TRANSGENIC MOUSE;

ANIMALS; BLOTTING, WESTERN; CELLS, CULTURED; CHROMATIN IMMUNOPRECIPITATION; DNA-BINDING PROTEINS; GENE EXPRESSION; GLUCURONOSYLTRANSFERASE; HEPATOCYTES; HUMANS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PROMOTER REGIONS (GENETICS); RECEPTORS, CYTOPLASMIC AND NUCLEAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SULFONAMIDES;

EID: 33747040567     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.21259     Document Type: Article

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