Induction of hepatic transporters multidrug resistance-associated proteins (Mrp) 3 and 4 by clofibrate is regulated by peroxisome proliferator-activated receptor α

Journal of Pharmacology and Experimental Therapeutics

Volumn 317, Issue 2, 2006, Pages 537-545

  Moffit, Jeffrey S ^a   Aleksunes, Lauren M ^a   Maher, Jonathan M ^b   Scheffer, George L ^c   Klaassen, Curtis D ^b   Manautou, José E ^a  

^a UNIVERSITY OF CONNECTICUT   (United States)

^b UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^c VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BREAST CANCER RESISTANCE PROTEIN; CARRIER PROTEIN; CLOFIBRATE; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN 1; MULTIDRUG RESISTANCE PROTEIN 1A; MULTIDRUG RESISTANCE PROTEIN 1B; MULTIDRUG RESISTANCE PROTEIN 2; MULTIDRUG RESISTANCE PROTEIN 3; MULTIDRUG RESISTANCE PROTEIN 4; ORGANIC ANION TRANSPORTER 1; ORGANIC ANION TRANSPORTER 1A1; ORGANIC ANION TRANSPORTER 1A4; ORGANIC ANION TRANSPORTER 1B2; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA AGONIST; SODIUM TAUROCHOLATE COTRANSPORTING POLYPEPTIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DOSE RESPONSE; DRUG MECHANISM; FUNCTIONAL PROTEOMICS; GENE EXPRESSION; LIVER FUNCTION; MALE; MOUSE; NONHUMAN; PHARMACODYNAMICS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; RECEPTOR INTRINSIC ACTIVITY; REGULATORY MECHANISM; UPREGULATION; WESTERN BLOTTING;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BLOTTING, WESTERN; CLOFIBRATE; GENE EXPRESSION; LIVER; MALE; MICE; MICE, INBRED STRAINS; MICE, KNOCKOUT; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; PPAR ALPHA; RNA, MESSENGER;

EID: 33645865553     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.105.093765     Document Type: Article

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