The power of meta-analysis in genome-wide association studies

Annual Review of Genomics and Human Genetics

Volumn 14, Issue , 2013, Pages 441-465

  Panagiotou, Orestis A ^a,g   Willer, Cristen J ^b   Hirschhorn, Joel N ^c,d,e   Ioannidis, John P A ^f  

^a UNIVERSITY OF IOANNINA   (Greece)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c BOSTON CHILDREN S HOSPITAL   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

^e BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^f STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Common variants; Consortium; Gene discovery; Missing heritability; Rare variants; Sample size; Variance explained

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; CAFFEINE; CALCIUM;

AGING; BODY FAT; CROHN DISEASE; DEATH; EFFECT SIZE; GENE CONTROL; GENE FREQUENCY; GENE LOCUS; GENE PROBE; GENETIC ASSOCIATION; GENETIC HETEROGENEITY; GENETIC TRAIT; GENETIC VARIABILITY; GENOTYPE; HARDY WEINBERG DISTRIBUTION LAW; HEREDITY; HERITABILITY; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; META ANALYSIS; MISSING HERITABILITY; MOLECULAR BIOLOGY; MULTIPLE SCLEROSIS; PARKINSON DISEASE; PHENOTYPE; QUANTITATIVE TRAIT LOCUS; REVIEW; RHEUMATOID ARTHRITIS; SAMPLE SIZE; ULCERATIVE COLITIS; WAIST CIRCUMFERENCE; HAPLOTYPE MAP; HUMAN GENOME; MEDICAL GENETICS; META ANALYSIS (TOPIC);

GENETICS, MEDICAL; GENOME, HUMAN; GENOME-WIDE ASSOCIATION STUDY; HAPMAP PROJECT; HUMANS; META-ANALYSIS AS TOPIC;

EID: 84884345860     PISSN: 15278204     EISSN: 1545293X     Source Type: Book Series    
DOI: 10.1146/annurev-genom-091212-153520     Document Type: Review

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