Abul Abbas: An epitome of scholarship

Journal of Autoimmunity

Volumn 45, Issue , 2013, Pages 1-6

  Eric Gershwin, M ^a   Shoenfeld, Yehuda ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b TEL AVIV UNIVERSITY   (Israel)

Author keywords

Autoimmunity; Immune regulation; Immunopathology; T cell subsets

Indexed keywords

ARTICLE; AUTOIMMUNE DISEASE; AUTOIMMUNITY; CAREER; HUMAN; IMMUNE SYSTEM; LYMPH NODE; MEDICAL LITERATURE; PRIORITY JOURNAL; PUBLICATION; SPLEEN;

AUTOIMMUNITY; IMMUNE REGULATION; IMMUNOPATHOLOGY; T CELL SUBSETS;

ALLERGY AND IMMUNOLOGY; AUTOIMMUNE DISEASES; AUTOIMMUNITY; HISTORY, 20TH CENTURY; HISTORY, 21ST CENTURY; HUMANS; INDIA; MALE; RESEARCH; UNITED STATES;

EID: 84884284703     PISSN: 08968411     EISSN: 10959157     Source Type: Journal    
DOI: 10.1016/j.jaut.2013.07.006     Document Type: Article

References (117)

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70. Grupp S.A., Campbell K., Mitchell R.N., Cambier J.C., Abbas A.K. Signaling-defective mutants of the B lymphocyte antigen receptor fail to associate with Ig-alpha and Ig-beta/gamma. The Journal of Biological Chemistry 1993, 268:25776-25779.
71. McKnight A.J., Perez V.L., Shea C.M., Gray G.S., Abbas A.K. Costimulator dependence of lymphokine secretion by naive and activated CD4+ T lymphocytes from TCR transgenic mice. Journal of Immunology 1994, 152:5220-5225.
72. McKnight A.J., Zimmer G.J., Fogelman I., Wolf S.F., Abbas A.K. Effects of IL-12 on helper T cell-dependent immune responses invivo. Journal of Immunology 1994, 152:2172-2179.
73. Sethna M.P., van Parijs L., Sharpe A.H., Abbas A.K., Freeman G.J. Anegative regulatory function of B7 revealed in B7-1 transgenic mice. Immunity 1994, 1:415-421.
74. Bliss J., Van Cleave V., Murray K., Wiencis A., Ketchum M., Maylor R., et al. IL-12, as an adjuvant, promotes a T helper 1 cell, but does not suppress a T helper 2 cell recall response. Journal of Immunology 1996, 156:887-894.
75. Cronin F.E., Jiang M., Abbas A.K., Grupp S.A. Role of mu heavy chain in B cell development. I. Blocked B cell maturation but complete allelic exclusion in the absence of Ig alpha/beta. Journal of Immunology 1998, 161:252-259.
76. Van Parijs L., Abbas A.K. Homeostasis and self-tolerance in the immune system: turning lymphocytes off. Science 1998, 280:243-248.
77. Van Parijs L., Biuckians A., Abbas A.K. Functional roles of Fas and Bcl-2-regulated apoptosis of T lymphocytes. Journal of Immunology 1998, 160:2065-2071.
78. Van Parijs L., Biuckians A., Ibragimov A., Alt F.W., Willerford D.M., Abbas A.K. Functional responses and apoptosis of CD25 (IL-2R alpha)-deficient T cells expressing a transgenic antigen receptor. Journal of Immunology 1997, 158:3738-3745.
79. Van Parijs L., Ibraghimov A., Abbas A.K. The roles of costimulation and Fas in T cell apoptosis and peripheral tolerance. Immunity 1996, 4:321-328.
80. Van Parijs L., Sethna M.P., Schweitzer A.N., Borriello F., Sharpe A.H., Abbas A.K. Functional consequences of dysregulated B7-1 (CD80) and B7-2 (CD86) expression in B or T lymphocytes of transgenic mice. Journal of Immunology 1997, 159:5336-5344.
81. Zhang B.W., Zimmer G., Chen J., Ladd D., Li E., Alt F.W., et al. Tcell responses in calcineurin A alpha-deficient mice. The Journal of Experimental Medicine 1996, 183:413-420.
82. Abbas A.K., Janeway C.A. Immunology: improving on nature in the twenty-first century. Cell. 2000, 100:129-138.
83. Dooms H., Abbas A.K. Life and death in effector T cells. Nature Immunology 2002, 3:797-798.
84. Greenwald R.J., Boussiotis V.A., Lorsbach R.B., Abbas A.K., Sharpe A.H. CTLA-4 regulates induction of anergy invivo. Immunity 2001, 14:145-155.
85. Kane L.P., Andres P.G., Howland K.C., Abbas A.K., Weiss A. Akt provides the CD28 costimulatory signal for up-regulation of IL-2 and IFN-gamma but not TH2 cytokines. Nature Immunology 2001, 2:37-44.
86. London C.A., Lodge M.P., Abbas A.K. Functional responses and costimulator dependence of memory CD4+ T cells. Journal of Immunology 2000, 164:265-272.
87. London C.A., Perez V.L., Abbas A.K. Functional characteristics and survival requirements of memory CD4+ T lymphocytes invivo. Journal of Immunology 1999, 162:766-773.
88. Refaeli Y., Van Parijs L., Abbas A.K. Genetic models of abnormal apoptosis in lymphocytes. Immunological Reviews 1999, 169:273-282.
89. Refaeli Y., Van Parijs L., Alexander S.I., Abbas A.K. Interferon gamma is required for activation-induced death of T lymphocytes. The Journal of Experimental Medicine 2002, 196:999-1005.
90. Walker L.S., Abbas A.K. The enemy within: keeping self-reactive T cells at bay in the periphery. Nature Reviews Immunology 2002, 2:11-19.
91. Walker L.S., Ausubel L.J., Chodos A., Bekarian N., Abbas A.K. CTLA-4 differentially regulates T cell responses to endogenous tissue protein versus exogenous immunogen. Journal of Immunology 2002, 169:6202-6209.
92. Abbas A.K., Sharpe A.H. Dendritic cells giveth and taketh away. Nature Immunology 2005, 6:227-228.
93. Eggena M.P., Walker L.S., Nagabhushanam V., Barron L., Chodos A., Abbas A.K. Cooperative roles of CTLA-4 and regulatory T cells in tolerance to an islet cell antigen. The Journal of Experimental Medicine 2004, 199:1725-1730.
94. Lohr J., Knoechel B., Nagabhushanam V., Abbas A.K. T-cell tolerance and autoimmunity to systemic and tissue-restricted self-antigens. Immunological Reviews 2005, 204:116-127.
95. Walker L.S., Chodos A., Eggena M., Dooms H., Abbas A.K. Antigen-dependent proliferation of CD4+ CD25+ regulatory T cells invivo. The Journal of Experimental Medicine 2003, 198:249-258.
96. Barron L., Knoechel B., Lohr J., Abbas A.K. Cutting edge: contributions of apoptosis and anergy to systemic T cell tolerance. Journal of Immunology 2008, 180:2762-2766.
97. Bour-Jordan H., Salomon B.L., Thompson H.L., Santos R., Abbas A.K., Bluestone J.A. Constitutive expression of B7-1 on B cells uncovers autoimmunity toward the B cell compartment in the nonobese diabetic mouse. Journal of Immunology 2007, 179:1004-1012.
98. Chikuma S., Abbas A.K., Bluestone J.A. B7-independent inhibition of T cells by CTLA-4. Journal of Immunology 2005, 175:177-181.
99. Dooms H., Abbas A.K. Control of CD4+ T-cell memory by cytokines and costimulators. Immunological Reviews 2006, 211:23-38.
100. Dooms H., Wolslegel K., Lin P., Abbas A.K. Interleukin-2 enhances CD4+ T cell memory by promoting the generation of IL-7R alpha-expressing cells. The Journal of Experimental Medicine 2007, 204:547-557.
101. Fife B.T., Griffin M.D., Abbas A.K., Locksley R.M., Bluestone J.A. Inhibition of T cell activation and autoimmune diabetes using a B cell surface-linked CTLA-4 agonist. The Journal of Clinical Investigation 2006, 116:2252-2261.
102. Hoyer K.K., Dooms H., Barron L., Abbas A.K. Interleukin-2 in the development and control of inflammatory disease. Immunological Reviews 2008, 226:19-28.
103. Hoyer K.K., Wolslegel K., Dooms H., Abbas A.K. Targeting T cell-specific costimulators and growth factors in a model of autoimmune hemolytic anemia. Journal of Immunology 2007, 179:2844-2850.
104. Knoechel B., Lohr J., Zhu S., Wong L., Hu D., Ausubel L., et al. Functional and molecular comparison of anergic and regulatory T lymphocytes. Journal of Immunology 2006, 176:6473-6483.
105. Lohr J., Knoechel B., Abbas A.K. Regulatory T cells in the periphery. Immunological Reviews 2006, 212:149-162.
106. Lohr J., Knoechel B., Wang J.J., Villarino A.V., Abbas A.K. Role of IL-17 and regulatory T lymphocytes in a systemic autoimmune disease. The Journal of Experimental Medicine 2006, 203:2785-2791.
107. Sharpe A.H., Abbas A.K. T-cell costimulation-biology, therapeutic potential, and challenges. The New England Journal of Medicine 2006, 355:973-975.
108. Barron L., Dooms H., Hoyer K.K., Kuswanto W., Hofmann J., O'Gorman W.E., et al. Cutting edge: mechanisms of IL-2-dependent maintenance of functional regulatory T cells. Journal of Immunology 2010, 185:6426-6430.
109. Caretto D., Katzman S.D., Villarino A.V., Gallo E., Abbas A.K. Cutting edge: the Th1 response inhibits the generation of peripheral regulatory T cells. Journal of Immunology 2010, 184:30-34.
110. Hoyer K.K., Kuswanto W.F., Gallo E., Abbas A.K. Distinct roles of helper T-cell subsets in a systemic autoimmune disease. Blood 2009, 113:389-395.
111. Katzman S.D., Gallo E., Hoyer K.K., Abbas A.K. Differential requirements for Th1 and Th17 responses to a systemic self-antigen. Journal of Immunology 2011, 186:4668-4673.
112. Katzman S.D., O'Gorman W.E., Villarino A.V., Gallo E., Friedman R.S., Krummel M.F., et al. Duration of antigen receptor signaling determines T-cell tolerance or activation. Proceedings of the National Academy of Sciences of the United States of America 2010, 107:18085-18090.
113. O'Gorman W.E., Dooms H., Thorne S.H., Kuswanto W.F., Simonds E.F., Krutzik P.O., et al. The initial phase of an immune response functions to activate regulatory T cells. Journal of Immunology 2009, 183:332-339.
114. Rosenblum M.D., Gratz I.K., Paw J.S., Abbas A.K. Treating human autoimmunity: current practice and future prospects. Science Translational Medicine 2012, 4. 125sr1.
115. Schmidt E.M., Wang C.J., Ryan G.A., Clough L.E., Qureshi O.S., Goodall M., et al. Ctla-4 controls regulatory T cell peripheral homeostasis and is required for suppression of pancreatic islet autoimmunity. Journal of Immunology 2009, 182:274-282.
116. Villarino A.V., Gallo E., Abbas A.K. STAT1-activating cytokines limit Th17 responses through both T-bet-dependent and -independent mechanisms. Journal of Immunology 2010, 185:6461-6471.
117. Villarino A.V., Katzman S.D., Gallo E., Miller O., Jiang S., McManus M.T., et al. Posttranscriptional silencing of effector cytokine mRNA underlies the anergic phenotype of self-reactive T cells. Immunity 2011, 34:50-60.