Immunology: Improving on nature in the twenty-first century

Cell

Volumn 100, Issue 1, 2000, Pages 129-138

  Abbas, Abul K ^a   Janeway Jr , Charles A ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN RECOGNITION; CLONAL ANERGY; EFFECTOR CELL; IMMUNE RESPONSE; IMMUNITY; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; LYMPHOCYTE FUNCTION; NONHUMAN; PRIORITY JOURNAL; REVIEW; TH1 CELL; TH2 CELL;

EID: 0034614546     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)81689-X     Document Type: Review

References (65)

1. Abbas, A.K., Lichtman, A.H., and Pober, J.S. (1997). Cellular and Molecular Immunology, Third Edition (Philadelphia: W.B. Saunders).
2. Agrawal, A., Eastman, Q.M., and Schatz, D.G. (1998). Transposition mediated by RAG1 and RAG2 and its implications for the evolution of the immune system. Nature 394, 744-751.
3. Alam, S.M., Davies, G.M., Lin, C.M., Zal, T., Nasholds, W., Jameson, S.C., Hogquist, K.A., Gascoigne, N.R., and Travers, P.J. (1999). Qualitative and quantitative differences in T cell receptor binding of agonist and antagonist ligands. Immunity 10, 227-237.
4. Altman, J.D., Moss, P.A.H., Goulder, P.J.R., Barouch, D.H., McHeyzer-Williams, M.G., Bell, J.I., McMichael, A.J., and Davis, M.M. (1996). Phenotypic analysis of antigen-specific T lymphocytes. Science 274, 94-96.
5. Babbitt, B.P., Allen, P.M., Matsueda, G., Haber, E., and Unanue, E.R. (1985). Binding of immunogenic peptides to la histocompatibility molecules. Nature 317, 359-361.
6. Banchereau, J., and Steinman, R.M. (1998). Dendritic cells and the control of immunity. Nature 392, 245-252.
7. Benacerraf, B., and McDevitt, H.O. (1972). Histocompatibility-linked immune response genes. Science 175, 273-279.
8. Berger, E.A., Murphy, P.M., and Farber, J.M. (1999). Chemokine receptors as HIV-1 coreceptors: Roles in viral entry, tropism, and disease. Annu. Rev. Immunol. 17, 657-700.
9. Bjorkman, P.J. (1997). MHC restriction in three dimensions: A view of T cell receptor/ligand interactions. Cell 89, 167-170.
10. Bjorkman, P.J., Saper, M.A., Samraoui, B., Bennett, W.S., Strominger, J.L., and Wiley, D.C. (1987). Structure of the human class I histocompatibility antigen, HLA-A2. Nature 329, 506-512.
11. Burnet, F.M. (1959). The Clonal Selection Theory (London: Cambridge University Press).
12. Cresswell, P. (1994). Assembly, transport, and function of MHC class II molecules. Annu. Rev. Immunol. 12, 259-293.
13. Dustin, M.L., Olszowy, M.W., Holdorf, A.D., Li, J., Bromley, S., Desai, N., Widder, P., Rosenberger, F., van der Merwe, P.A., Allen, P.M., and Shaw, A.S. (1998). A novel adaptor protein orchestrates receptor patterning and cytoskeletal polarity in T-cell contacts. Cell 94, 667-677.
14. Ernst, B., Lee, D.S., Chang, J.M., Sprent, J., and Surh, C.D. (1999). The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery. Immunity 11, 173-181.
15. Foy, T.M., Aruffo, A., Bajorath, J., Buhlmann, J.E., and Noelle, R.J. (1996). Immune regulation by CD40 and its ligand GP39. Annu. Rev. Immunol. 14, 591-617.
16. Garboczi, D.N., Ghosh, P., Utz, U., Fan, Q.R., Biddison, W.E., and Wiley, D.C. (1996). Structure of the complex between human T-cell receptor, viral peptide and HLA-A2. Nature 384, 134-141.
17. Garcia, K.C., Degano, M., Stanfield, R.L., Brunmark, A., Jackson, M.R., Peterson, P.A., Teyton, L., and Wilson, I.A. (1996). An alphabeta T cell receptor structure at 2.5 A and its orientation in the TCR-MHC complex. Science 274, 209-219.
18. Germain, R.N. (1994). MHC-dependent antigen processing and peptide presentation: Providing ligands for T lymphocyte activation. Cell 76, 287-299.
19. Goldrath, A.W., and Bevan, M.J. (1999). Low-affinity ligands for the TCR drive proliferation of mature CD8+ T cells in lymphopenic hosts. Immunity 11, 183-190.
20. Gowans, J.L., McGregor, D.D., Cowen, D.M., and Ford, C.E. (1962). Initiation of immune responses by small lymphocytes. Nature 196, 651-655.
21. Harding, F.A., McArthur, J.G., Gross, J.A., Raulet, D.H., and Allison, J.P. (1992). CD28-mediated signaling co-stimulates murine T cells and prevents induction of anergy in T-cell clones. Nature 356, 607-609.
22. Hendrick, S.M., Cohen, D.I., Neilsen, E.A., and Davis, M.M. (1984). Isolation of cDNA clones encoding T cell-specific membrane-associated proteins. Nature 308, 149-153.
23. Hiom, K., Melek, M., and Gellert, M. (1998). DNA transposition by the RAG1 and RAG2 proteins: A possible source of oncogenic translocations. Cell 94, 463-470.
24. Huang, Y., Paxton, W.A., Wolinsky, S.M., Neumann, A.U., Zhang, L., He, T., Kang, S., Ceradini, D., Jin, Z., Yazdanbakhsh, K., et al. (1996). The role of a mutant CCR5 allele in HIV-1 transmission and disease progression. Nat. Med. 2, 1240-1243.
25. Janeway, C.A., Jr. (1989). Approaching the asymptote? Evolution and revolution in immunology. Cold Spring Harb. Symp. Quant. Biol. 54, 1-13.
26. Janeway, C.A., Travers, P., Walport, M., and Capra, D. (1999). Immunobiology: The Immune System in Health and Disease, Fourth Edition (London: Garland Publishing).
27. Jenner, E. (1798). An Inquiry Into the Causes and Effects of the Variola Vacciniae, A Disease Discovered in Some of the Western Counties of England, Particulary Gloucestershire, and Known by the Name of Cowpox (London: for the author by Sompson Lew).
28. Kappler, J.W., Skidmore, B., White, J., and Marrack, P. (1981). Antigen-inducible, H-2-restricted, interleukin-2-producing T cell hybridomas. Lack of independent antigen and H-2 recognition. J. Exp. Med. 153, 1198-1214.
29. Katz, D.H., Hamaoka, T., Dorf, M.E., Maurer, P.H., and Benacerraf, B. (1973). Cell interactions between histoincompatible T and B lymphocytes. IV. Involvement of the immune response (Ir) gene in the control of lymphocyte interactions in responses controlled by the gene. J. Exp. Med. 138, 734-739.
30. Kenyon, N.S., Chatzipetrou, M., Masetti, M., Ranuncoli, A., Oliveira, M., Wagner, J.L., Kirk, A.D., Harlan, D.M., Burkly, L.C., and Ricordi, C. (1999). Long-term survival and function of intrahepatic islet allografts in rhesus monkeys treated with humanized anti-CD154. Proc. Natl. Acad. Sci. USA 96, 8132-8137.
31. Kim, J., Woods, A., Becker-Dunn, E., and Bottomly, K. (1985). Distinct functional phenotypes of cloned la-restricted helper T cells. J. Exp. Med. 162, 188-201.
32. Kirk, A.D., Burkly, L.C., Batty, D.S., Baumgartner, R.E., Berning, J.D., Buchanan, K., Fechner, J.H., Jr., Germond, R.L., Kampen, R.L., Patterson, N.B., et al. (1999). Treatment with humanized monoclonal antibody against CD154 prevents acute renal allograft rejection in nonhuman primates. Nat. Med. 5, 686-693.
33. Köhler, G., and Milstein, C. (1975). Continuous cultures of fused cells secreting antibody of predefined structure. Nature 256, 495-497.
34. Lam, K.P., Kuhn, R., and Rajewsky, K. (1997). In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death. Cell 90, 1073-1083.
35. Lee, K.M., Chuang, E., Griffin, M., Khattri, R., Hong, D.K., Zhang, W., Straus, D., Samelson, L.E., Thompson, C.B., and Bluestone, J.A. (1998). Molecular basis of T cell inactivation by CTLA-4. Science 282, 2263-2266.
36. Libby, P., and Ridker, P.M. (1999). Novel inflammatory markers of coronary risk: Theory versus practice. Circulation 100, 1148-1150.
37. Linsley, P.S., and Ledbetter, J.A. (1993). The role of the CD28 receptor during T cell responses to antigen. Annu. Rev. Immunol. 11, 191-212.
38. Ljunggren, H.G., and Karre, K. (1990). In search of the 'missing self': MHC molecules and NK cell recognition. Immunol. Today 11, 237-244.
39. Markees, T.G., Phillips, N.E., Gordon, E.J., Noelle, R.J., Shultz, L.D., Mordes, J.P., Greiner, D.L., and Rossini, A.A. (1998). Long-term survival of skin allografts induced by donor splenocytes and anti-CD154 antibody in thymectomized mice requires CD4(+) T cells, interferon-gamma, and CTLA4. J. Clin. Invest. 101, 2446-2455.
40. Medzhitov, R., Preston-Hurlburt, P., and Janeway, C.A., Jr. (1997). A human homologue of the drosophila toll protein signals activation of adaptive immunity. Nature 388, 394-397.
41. Melchers, F., Rolink, A.G., and Schaniel, C. (1999). The role of chemokines in regulating cell migration during humoral immune responses. Cell 99, 351-354.
42. Metchnikoff, E. (1893). Lectures on the Comparative Pathology of Inflammation (London: Kegan, Paul, Trench, Trubner).
43. Monks, C.R., Freiberg, B.A., Kupfer, H., Sciaky, N., and Kupfer, A. (1998). Three-dimensional segregation of supramolecular activation clusters in T cells. Nature 395, 82-86.
44. Mosmann, T.R., Cherwinski, H., Bond, M.W., Giedlin, M.A., and CoffMan, R.L. (1986). Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. J. Immunol. 136, 2348-2357.
45. Murali-Krishna, K., Altman, J.D., Suresh, M., Sourdive, D.J., Zajac, A.J., Miller, J.D., Slansky, J., and Ahmed, R. (1998). Counting antigen-specific CD8 T cells: A reevaluation of bystander activation during viral infection. Immunity 8, 177-187.
46. Nakagawa, T.Y., Brissette, W.H., Lira, P.D., Griffiths, R.J., Petrushova, N., Stock, J., McNeish, J.D., Eastman, S.E., Howard, E.D., Clarke, S.R., et al. (1999). Impaired invariant chain degradation and antigen presentation and diminished collagen-induced arthritis in cathepsin S null mice. Immunity 10, 207-217.
47. Nossal, G.J. (1994). Negative selection of lymphocytes. Cell 76, 229-239.
48. Ogg, G.S., Jin, X., Bonhoeffer, S., Dunbar, P.R., Nowak, M.A., Monard, S., Segal, J.P., Cao, Y., Rowland-Jones, S.L., Cerundolo, V., et al. (1998). Quantitation of HIV-1-specific cytotoxic T lymphocytes and plasma load of viral RNA. Science 279, 2103-2106.
49. Paul, W.E. (1999). Fundamental Immunology (Philadelphia: Lippincott-Raven), p. 1589.
50. Ploegh, H.L. (1998). Viral strategies of immune evasion. Science 280, 248-253.
51. Rose, N.R., and Mackay, I.R. (1998). The Autoimmune Diseases, Third Edition (San Diego: Academic Press).
52. Rosenthal, A.S., and Shevach, E.M. (1973). Function of macrophages in antigen recognition by guinea pig T lymphocytes. I. Requirement for histocompatible macrophages and lymphocytes. J. Exp. Med. 138, 1194-1212.
53. Sallusto, F., and Lanzavecchia, A. (1999). Mobilizing dendritic cells for tolerance, priming, and chronic inflammation. J. Exp. Med. 189, 611-614.
54. Sant'Angelo, D.B., Waterbury, G., Preston-Hurlburt, P., Yoon, S.T., Medzhitov, R., Hong, S.C., and Janeway, C.A., Jr. (1996). The specificity and orientation of a TCR to its peptide-MHC class II ligands. Immunity 4, 367-376.
55. Schenk, D., Barbour, R., Dunn, W., Gordon, G., Grajeda, H., Guido, T., Hu, K., Huang, J., Johnson-Wood, K., Khan, K., et al. (1999). Immunization with amyloid-beta attenuates alzheimer-disease-like pathology in the PDAPP mouse. Nature 400, 173-177.
56. Schwartz, R.H. (1992). Costimulation of T lymphocytes: The role of CD28, CTLA-4, and B7/BB1 in interleukin-2 production and immunotherapy. Cell 71, 1065-1068.
57. Tanchot, C., Lemonnier, F.A., Perarnau, B., Freitas, A.A., and Rocha, B. (1997). Differential requirements for survival and proliferation of CD8 naive or memory T cells. Science 276, 2057-2062.
58. Tonegawa, S., Hozumi, N., Matthyssens, G., and Schuller, R. (1977). Somatic changes in the content and context of immunoglobulin genes. Cold Spring Harb. Symp. Quant. Biol. 41, 877-889.
59. Van Parijs, L., and Abbas, A.K. (1998). Homeostasis and self-tolerance in the immune system: Turning lymphocytes off. Science 280, 243-248.
60. Viret, C., Wong, F.S., and Janeway, C.A., Jr. (1999). Designing and maintaining the mature TCR repertoire: The continuum of self-peptide:self-MHC complex recognition. Immunity 10, 559-568.
61. von Boehmer, H. (1994). Positive selection of lymphocytes. Cell 76, 219-228.
62. Weiss, A., and Littman, D.R. (1994). Signal transduction by lymphocyte antigen receptors. Cell 76, 263-274.
63. Yokoyama, W.M., and Seaman, W.E. (1993). The Ly-49 and NKR-P1 gene families encoding lectin-like receptors on natural killer cells: The NK gene complex. Annu. Rev. Immunol. 11, 613-635.
64. Zinkernagel, R.M., and Doherty, P.C. (1974). Immunological surveillance against altered self components by sensitised T lymphocytes in lymphocytic choriomeningitis. Nature 251, 547-548.
65. Zuniga-Pflucker, J.C., Di, J., and Lenardo, M.J. (1995). Requirement for TNF-alpha and IL-1 alpha in fetal thymocyte commitment and differentiation. Science 268, 1906-1909.