-
2
-
-
0033851221
-
Autoimmune diseases: A leading cause of death among young and middle-aged women in the United States
-
S. J. Walsh, L. M. Rau, Autoimmune diseases: A leading cause of death among young and middle-aged women in the United States. Am. J. Public Health 90, 1463-1466 (2000).
-
(2000)
Am. J. Public Health
, vol.90
, pp. 1463-1466
-
-
Walsh, S.J.1
Rau, L.M.2
-
3
-
-
79960835109
-
Interrogating the repertoire: Broadening the scope of peptide - MHC multimer analysis
-
M. M. Davis, J. D. Altman, E. W. Newell, Interrogating the repertoire: Broadening the scope of peptide - MHC multimer analysis. Nat. Rev. Immunol. 11, 551-558 (2011).
-
(2011)
Nat. Rev. Immunol.
, vol.11
, pp. 551-558
-
-
Davis, M.M.1
Altman, J.D.2
Newell, E.W.3
-
4
-
-
74049160009
-
Mechanisms maintaining peripheral tolerance
-
D. L. Mueller, Mechanisms maintaining peripheral tolerance. Nat. Immunol. 11, 21-27 (2010).
-
(2010)
Nat. Immunol.
, vol.11
, pp. 21-27
-
-
Mueller, D.L.1
-
5
-
-
0026738641
-
Long-term survival of xenogeneic pancreatic islet grafts induced by CTLA4lg
-
D. J. Lenschow, Y. Zeng, J. R. Thistlethwaite, A. Montag, W. Brady, M. G. Gibson, P. S. Linsley, J. A. Bluestone, Long-term survival of xenogeneic pancreatic islet grafts induced by CTLA4lg. Science 257, 789-792 (1992).
-
(1992)
Science
, vol.257
, pp. 789-792
-
-
Lenschow, D.J.1
Zeng, Y.2
Thistlethwaite, J.R.3
Montag, A.4
Brady, W.5
Gibson, M.G.6
Linsley, P.S.7
Bluestone, J.A.8
-
6
-
-
76649140079
-
Abatacept for rheumatoid arthritis: A Cochrane systematic review
-
L. J. Maxwell, J. A. Singh, Abatacept for rheumatoid arthritis: A Cochrane systematic review. J. Rheumatol. 37, 234-245 (2010).
-
(2010)
J. Rheumatol.
, vol.37
, pp. 234-245
-
-
Maxwell, L.J.1
Singh, J.A.2
-
7
-
-
79953701653
-
Abatacept in the treatment of patients with psoriatic arthritis: Results of a six-month, multicenter, randomized, double-blind, placebo-controlled, phase II trial
-
P. Mease, M. C. Genovese, G. Gladstein, A. J. Kivitz, C. Ritchlin, P. P. Tak, J. Wollenhaupt, O. Bahary, J. C. Becker, S. Kelly, L. Sigal, J. Teng, D. Gladman, Abatacept in the treatment of patients with psoriatic arthritis: Results of a six-month, multicenter, randomized, double-blind, placebo-controlled, phase II trial. Arthritis Rheum. 63, 939-948 (2011).
-
(2011)
Arthritis Rheum.
, vol.63
, pp. 939-948
-
-
Mease, P.1
Genovese, M.C.2
Gladstein, G.3
Kivitz, A.J.4
Ritchlin, C.5
Tak, P.P.6
Wollenhaupt, J.7
Bahary, O.8
Becker, J.C.9
Kelly, S.10
Sigal, L.11
Teng, J.12
Gladman, D.13
-
8
-
-
79960912796
-
Co-stimulation modulation with abatacept in patients with recent-onset type 1 diabetes: A randomised, double-blind, placebo-controlled trial
-
Type 1 Diabetes TrialNet Abatacept Study Group
-
T. Orban, B. Bundy, D. J. Becker, L. A. DiMeglio, S. E. Gitelman, R. Goland, P. A. Gottlieb, C. J. Greenbaum, J. B. Marks, R. Monzavi, A. Moran, P. Raskin, H. Rodriguez, W. E. Russell, D. Schatz, D. Wherrett, D. M. Wilson, J. P. Krischer, J. S. Skyler; Type 1 Diabetes TrialNet Abatacept Study Group, Co-stimulation modulation with abatacept in patients with recent-onset type 1 diabetes: A randomised, double-blind, placebo-controlled trial. Lancet 378, 412-419 (2011).
-
(2011)
Lancet
, vol.378
, pp. 412-419
-
-
Orban, T.1
Bundy, B.2
Becker, D.J.3
DiMeglio, L.A.4
Gitelman, S.E.5
Goland, R.6
Gottlieb, P.A.7
Greenbaum, C.J.8
Marks, J.B.9
Monzavi, R.10
Moran, A.11
Raskin, P.12
Rodriguez, H.13
Russell, W.E.14
Schatz, D.15
Wherrett, D.16
Wilson, D.M.17
Krischer, J.P.18
Skyler, J.S.19
-
9
-
-
54049093695
-
CTLA4Ig treatment in patients with multiple sclerosis: An open-label, phase 1 clinical trial
-
V. Viglietta, K. Bourcier, G. J. Buckle, B. Healy, H. L. Weiner, D. A. Hafler, S. Egorova, C. R. G. Guttmann, J. R. Rusche, S. J. Khoury, CTLA4Ig treatment in patients with multiple sclerosis: An open-label, phase 1 clinical trial. Neurology 71, 917-924 (2008).
-
(2008)
Neurology
, vol.71
, pp. 917-924
-
-
Viglietta, V.1
Bourcier, K.2
Buckle, G.J.3
Healy, B.4
Weiner, H.L.5
Hafler, D.A.6
Egorova, S.7
Guttmann, C.R.G.8
Rusche, J.R.9
Khoury, S.J.10
-
10
-
-
77957682858
-
The efficacy and safety of abatacept in patients with non - Life-threatening manifestations of systemic lupus erythematosus: Results of a twelve-month, multicenter, exploratory, phase IIb, randomized, double-blind, placebo-controlled trial
-
J. T. Merrill, R. Burgos-Vargas, R. Westhovens, A. Chalmers, D. D'Cruz, D. J. Wallace, S. C. Bae, L. Sigal, J. C. Becker, S. Kelly, K. Raghupathi, T. Li, Y. Peng, M. Kinaszczuk, P. Nash, The efficacy and safety of abatacept in patients with non - life-threatening manifestations of systemic lupus erythematosus: Results of a twelve-month, multicenter, exploratory, phase IIb, randomized, double-blind, placebo-controlled trial. Arthritis Rheum. 62, 3077-3087 (2010).
-
(2010)
Arthritis Rheum.
, vol.62
, pp. 3077-3087
-
-
Merrill, J.T.1
Burgos-Vargas, R.2
Westhovens, R.3
Chalmers, A.4
D'Cruz, D.5
Wallace, D.J.6
Bae, S.C.7
Sigal, L.8
Becker, J.C.9
Kelly, S.10
Raghupathi, K.11
Li, T.12
Peng, Y.13
Kinaszczuk, M.14
Nash, P.15
-
11
-
-
77958020886
-
Targeting lymphocyte co-stimulation: From bench to bedside
-
N. J. Felix, A. Suri, L. Salter-Cid, S. G. Nadler, S. Gujrathi, M. Corbo, R. Aranda, Targeting lymphocyte co-stimulation: From bench to bedside. Autoimmunity 43, 514-525 (2010).
-
(2010)
Autoimmunity
, vol.43
, pp. 514-525
-
-
Felix, N.J.1
Suri, A.2
Salter-Cid, L.3
Nadler, S.G.4
Gujrathi, S.5
Corbo, M.6
Aranda, R.7
-
12
-
-
0035059417
-
Complexities of CD28/B7: CTLA-4 costimulatory pathways in autoimmunity and transplantation
-
B. Salomon, J. A. Bluestone, Complexities of CD28/B7: CTLA-4 costimulatory pathways in autoimmunity and transplantation. Annu. Rev. Immunol. 19, 225-252 (2001).
-
(2001)
Annu. Rev. Immunol.
, vol.19
, pp. 225-252
-
-
Salomon, B.1
Bluestone, J.A.2
-
14
-
-
0347785480
-
Control of regulatory T cell development by the transcription factor Foxp3
-
S. Hori, T. Nomura, S. Sakaguchi, Control of regulatory T cell development by the transcription factor Foxp3. Science 299, 1057-1061 (2003).
-
(2003)
Science
, vol.299
, pp. 1057-1061
-
-
Hori, S.1
Nomura, T.2
Sakaguchi, S.3
-
16
-
-
33746338535
-
Interleukin-10-secreting type 1 regulatory T cells in rodents and humans
-
M. G. Roncarolo, S. Gregori, M. Battaglia, R. Bacchetta, K. Fleischhauer, M. K. Levings, Interleukin-10-secreting type 1 regulatory T cells in rodents and humans. Immunol. Rev. 212, 28-50 (2006).
-
(2006)
Immunol. Rev.
, vol.212
, pp. 28-50
-
-
Roncarolo, M.G.1
Gregori, S.2
Battaglia, M.3
Bacchetta, R.4
Fleischhauer, K.5
Levings, M.K.6
-
17
-
-
33746369415
-
Regulatory T-cell physiology and application to treat autoimmunity
-
Q. Tang, J. A. Bluestone, Regulatory T-cell physiology and application to treat autoimmunity. Immunol. Rev. 212, 217-237 (2006).
-
(2006)
Immunol. Rev.
, vol.212
, pp. 217-237
-
-
Tang, Q.1
Bluestone, J.A.2
-
18
-
-
33751207432
-
Cell-surface IL-7 receptor expression facilitates the purification of FOXP3+ regulatory T cells
-
A. H. Banham, Cell-surface IL-7 receptor expression facilitates the purification of FOXP3+ regulatory T cells. Trends Immunol. 27, 541-544 (2006).
-
(2006)
Trends Immunol.
, vol.27
, pp. 541-544
-
-
Banham, A.H.1
-
20
-
-
47249102067
-
+ T-regulatory cells: Toward therapy for human diseases
-
+ T-regulatory cells: Toward therapy for human diseases. Immunol. Rev. 223, 391-421 (2008).
-
(2008)
Immunol. Rev.
, vol.223
, pp. 391-421
-
-
Allan, S.E.1
Broady, R.2
Gregori, S.3
Himmel, M.E.4
Locke, N.5
Roncarolo, M.G.6
Bacchetta, R.7
Levings, M.K.8
-
21
-
-
79956258982
-
regs) with minimal loss of in vivo functional activity
-
regs) with minimal loss of in vivo functional activity. Sci. Transl. Med. 3, 83ra41 (2011).
-
(2011)
Sci. Transl. Med.
, vol.3
-
-
Hippen, K.L.1
Merkel, S.C.2
Schirm, D.K.3
Sieben, C.M.4
Sumstad, D.5
Kadidlo, D.M.6
McKenna, D.H.7
Bromberg, J.S.8
Levine, B.L.9
Riley, J.L.10
June, C.H.11
Scheinberg, P.12
Douek, D.C.13
Miller, J.S.14
Wagner, J.E.15
Blazar, B.R.16
-
22
-
-
62749201002
-
Expansion of human regulatory T-cells from patients with type 1 diabetes
-
A. L. Putnam, T. M. Brusko, M. R. Lee, W. Liu, G. L. Szot, T. Ghosh, M. A. Atkinson, J. A. Bluestone, Expansion of human regulatory T-cells from patients with type 1 diabetes. Diabetes 58, 652-662 (2009).
-
(2009)
Diabetes
, vol.58
, pp. 652-662
-
-
Putnam, A.L.1
Brusko, T.M.2
Lee, M.R.3
Liu, W.4
Szot, G.L.5
Ghosh, T.6
Atkinson, M.A.7
Bluestone, J.A.8
-
23
-
-
33745861719
-
+ T cells
-
+ T cells. J. Immunol. 177, 944-949 (2006).
-
(2006)
J. Immunol.
, vol.177
, pp. 944-949
-
-
Valmori, D.1
Tosello, V.2
Souleimanian, N.E.3
Godefroy, E.4
Scotto, L.5
Wang, Y.6
Ayyoub, M.7
-
24
-
-
79251589897
-
Retinoic acid and rapamycin differentially affect and synergistically promote the ex vivo expansion of natural human T regulatory cells
-
T. N. Golovina, T. Mikheeva, T. M. Brusko, B. R. Blazar, J. A. Bluestone, J. L. Riley, Retinoic acid and rapamycin differentially affect and synergistically promote the ex vivo expansion of natural human T regulatory cells. PLoS One 6, e15868 (2011).
-
(2011)
PLoS One
, vol.6
-
-
Golovina, T.N.1
Mikheeva, T.2
Brusko, T.M.3
Blazar, B.R.4
Bluestone, J.A.5
Riley, J.L.6
-
26
-
-
69049107358
-
Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo
-
X. Zhou, S. L. Bailey-Bucktrout, L. T. Jeker, C. Penaranda, M. Martínez-Llordella, M. Ashby, M. Nakayama, W. Rosenthal, J. A. Bluestone, Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo. Nat. Immunol. 10, 1000-1007 (2009).
-
(2009)
Nat. Immunol.
, vol.10
, pp. 1000-1007
-
-
Zhou, X.1
Bailey-Bucktrout, S.L.2
Jeker, L.T.3
Penaranda, C.4
Martínez-Llordella, M.5
Ashby, M.6
Nakayama, M.7
Rosenthal, W.8
Bluestone, J.A.9
-
27
-
-
63849183918
-
+ regulatory T cells in humans
-
+ regulatory T cells in humans. Proc. Natl. Acad. Sci. U.S.A. 106, 4793-4798 (2009).
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 4793-4798
-
-
Voo, K.S.1
Wang, Y.H.2
Santori, F.R.3
Boggiano, C.4
Wang, Y.H.5
Arima, K.6
Bover, L.7
Hanabuchi, S.8
Khalili, J.9
Marinova, E.10
Zheng, B.11
Littman, D.R.12
Liu, Y.J.13
-
28
-
-
65549088243
-
IL-17-producing human peripheral regulatory T cells retain suppressive function
-
G. Beriou, C. M. Costantino, C. W. Ashley, L. Yang, V. K. Kuchroo, C. Baecher-Allan, D. A. Hafler, IL-17-producing human peripheral regulatory T cells retain suppressive function. Blood 113, 4240-4249 (2009).
-
(2009)
Blood
, vol.113
, pp. 4240-4249
-
-
Beriou, G.1
Costantino, C.M.2
Ashley, C.W.3
Yang, L.4
Kuchroo, V.K.5
Baecher-Allan, C.6
Hafler, D.A.7
-
30
-
-
79956288367
-
Human regulatory T cells with alloantigen specificity are more potent inhibitors of alloimmune skin graft damage than polyclonal regulatory T cells
-
P. Sagoo, N. Ali, G. Garg, F. O. Nestle, R. I. Lechler, G. Lombardi, Human regulatory T cells with alloantigen specificity are more potent inhibitors of alloimmune skin graft damage than polyclonal regulatory T cells. Sci. Transl. Med. 3, 83ra42 (2011).
-
(2011)
Sci. Transl. Med.
, vol.3
-
-
Sagoo, P.1
Ali, N.2
Garg, G.3
Nestle, F.O.4
Lechler, R.I.5
Lombardi, G.6
-
31
-
-
79953809817
-
Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation
-
M. Di Ianni, F. Falzetti, A. Carotti, A. Terenzi, F. Castellino, E. Bonifacio, B. Del Papa, T. Zei, R. I. Ostini, D. Cecchini, T. Aloisi, K. Perruccio, L. Ruggeri, C. Balucani, A. Pierini, P. Sportoletti, C. Aristei, B. Falini, Y. Reisner, A. Velardi, F. Aversa, M. F. Martelli, Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation. Blood 117, 3921-3928 (2011).
-
(2011)
Blood
, vol.117
, pp. 3921-3928
-
-
Di Ianni, M.1
Falzetti, F.2
Carotti, A.3
Terenzi, A.4
Castellino, F.5
Bonifacio, E.6
Del Papa, B.7
Zei, T.8
Ostini, R.I.9
Cecchini, D.10
Aloisi, T.11
Perruccio, K.12
Ruggeri, L.13
Balucani, C.14
Pierini, A.15
Sportoletti, P.16
Aristei, C.17
Falini, B.18
Reisner, Y.19
Velardi, A.20
Aversa, F.21
Martelli, M.F.22
more..
-
32
-
-
20644470338
-
Full haplotype-mismatched hematopoietic stem-cell transplantation: A phase II study in patients with acute leukemia at high risk of relapse
-
F. Aversa, A. Terenzi, A. Tabilio, F. Falzetti, A. Carotti, S. Ballanti, R. Felicini, F. Falcinelli, A. Velardi, L. Ruggeri, T. Aloisi, J. P. Saab, A. Santucci, K. Perruccio, M. P. Martelli, C. Mecucci, Y. Reisner, M. F. Martelli, Full haplotype-mismatched hematopoietic stem-cell transplantation: A phase II study in patients with acute leukemia at high risk of relapse. J. Clin. Oncol. 23, 3447-3454 (2005).
-
(2005)
J. Clin. Oncol.
, vol.23
, pp. 3447-3454
-
-
Aversa, F.1
Terenzi, A.2
Tabilio, A.3
Falzetti, F.4
Carotti, A.5
Ballanti, S.6
Felicini, R.7
Falcinelli, F.8
Velardi, A.9
Ruggeri, L.10
Aloisi, T.11
Saab, J.P.12
Santucci, A.13
Perruccio, K.14
Martelli, M.P.15
Mecucci, C.16
Reisner, Y.17
Martelli, M.F.18
-
33
-
-
78751696183
-
Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: Safety profile and detection kinetics
-
C. G. Brunstein, J. S. Miller, Q. Cao, D. H. McKenna, K. L. Hippen, J. Curtsinger, T. Defor, B. L. Levine, C. H. June, P. Rubinstein, P. B. McGlave, B. R. Blazar, J. E. Wagner, Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: Safety profile and detection kinetics. Blood 117, 1061-1070 (2011).
-
(2011)
Blood
, vol.117
, pp. 1061-1070
-
-
Brunstein, C.G.1
Miller, J.S.2
Cao, Q.3
McKenna, D.H.4
Hippen, K.L.5
Curtsinger, J.6
Defor, T.7
Levine, B.L.8
June, C.H.9
Rubinstein, P.10
McGlave, P.B.11
Blazar, B.R.12
Wagner, J.E.13
-
34
-
-
79955477145
-
Immunological mechanisms of allergen-specific immunotherapy
-
M. Jutel, C. A. Akdis, Immunological mechanisms of allergen-specific immunotherapy. Allergy 66, 725-732 (2011).
-
(2011)
Allergy
, vol.66
, pp. 725-732
-
-
Jutel, M.1
Akdis, C.A.2
-
35
-
-
58149306013
-
In vivo switch to IL-10-secreting T regulatory cells in high dose allergen exposure
-
F. Meiler, J. Zumkehr, S. Klunker, B. Rückert, C. A. Akdis, M. Akdis, In vivo switch to IL-10-secreting T regulatory cells in high dose allergen exposure. J. Exp. Med. 205, 2887-2898 (2008).
-
(2008)
J. Exp. Med.
, vol.205
, pp. 2887-2898
-
-
Meiler, F.1
Zumkehr, J.2
Klunker, S.3
Rückert, B.4
Akdis, C.A.5
Akdis, M.6
-
36
-
-
80051792906
-
Mechanisms of immunotherapy to wasp and bee venom
-
C. Ozdemir, U. C. Kucuksezer, M. Akdis, C. A. Akdis, Mechanisms of immunotherapy to wasp and bee venom. Clin. Exp. Allergy 41, 1226-1234 (2011).
-
(2011)
Clin. Exp. Allergy
, vol.41
, pp. 1226-1234
-
-
Ozdemir, C.1
Kucuksezer, U.C.2
Akdis, M.3
Akdis, C.A.4
-
37
-
-
77949901839
-
Birch pollen immunotherapy leads to differential induction of regulatory T cells and delayed helper T cell immune deviation
-
C. Möbs, C. Slotosch, H. Löffler, T. Jakob, M. Hertl, W. Pfützner, Birch pollen immunotherapy leads to differential induction of regulatory T cells and delayed helper T cell immune deviation. J. Immunol. 184, 2194-2203 (2010).
-
(2010)
J. Immunol.
, vol.184
, pp. 2194-2203
-
-
Möbs, C.1
Slotosch, C.2
Löffler, H.3
Jakob, T.4
Hertl, M.5
Pfützner, W.6
-
39
-
-
80054814347
-
Specific immunotherapy and turning off the T cell: How does it work?
-
C. Ozdemir, U. C. Kucuksezer, M. Akdis, C. A. Akdis, Specific immunotherapy and turning off the T cell: How does it work? Ann. Allergy Asthma Immunol. 107, 381-392 (2011).
-
(2011)
Ann. Allergy Asthma Immunol.
, vol.107
, pp. 381-392
-
-
Ozdemir, C.1
Kucuksezer, U.C.2
Akdis, M.3
Akdis, C.A.4
-
40
-
-
84355162741
-
Response to self antigen imprints regulatory memory in tissues
-
M. D. Rosenblum, I. K. Gratz, J. S. Paw, K. Lee, A. Marshak-Rothstein, A. K. Abbas, Response to self antigen imprints regulatory memory in tissues. Nature 480, 538-542 (2011).
-
(2011)
Nature
, vol.480
, pp. 538-542
-
-
Rosenblum, M.D.1
Gratz, I.K.2
Paw, J.S.3
Lee, K.4
Marshak-Rothstein, A.5
Abbas, A.K.6
-
41
-
-
57349101501
-
Spliceosomal peptide P140 for immunotherapy of systemic lupus erythematosus: Results of an early phase II clinical trial
-
S. Muller, F. Monneaux, N. Schall, R. K. Rashkov, B. A. Oparanov, P. Wiesel, J. M. Geiger, R. Zimmer, Spliceosomal peptide P140 for immunotherapy of systemic lupus erythematosus: Results of an early phase II clinical trial. Arthritis Rheum. 58, 3873-3883 (2008).
-
(2008)
Arthritis Rheum.
, vol.58
, pp. 3873-3883
-
-
Muller, S.1
Monneaux, F.2
Schall, N.3
Rashkov, R.K.4
Oparanov, B.A.5
Wiesel, P.6
Geiger, J.M.7
Zimmer, R.8
-
42
-
-
80052908633
-
Immune intervention in type 1 diabetes
-
A. W. Michels, G. S. Eisenbarth, Immune intervention in type 1 diabetes. Semin. Immunol. 23, 214-219 (2011).
-
(2011)
Semin. Immunol.
, vol.23
, pp. 214-219
-
-
Michels, A.W.1
Eisenbarth, G.S.2
-
43
-
-
0035944844
-
β-Cell function in new-onset type 1 diabetes and immunomodulation with a heat-shock protein peptide (DiaPep277): A randomised, double-blind, phase II trial
-
I. Raz, D. Elias, A. Avron, M. Tamir, M. Metzger, I. R. Cohen, β-Cell function in new-onset type 1 diabetes and immunomodulation with a heat-shock protein peptide (DiaPep277): A randomised, double-blind, phase II trial. Lancet 358, 1749-1753 (2001).
-
(2001)
Lancet
, vol.358
, pp. 1749-1753
-
-
Raz, I.1
Elias, D.2
Avron, A.3
Tamir, M.4
Metzger, M.5
Cohen, I.R.6
-
44
-
-
80755168854
-
C-peptide response and HLA genotypes in subjects with recent-onset type 1 diabetes after immunotherapy with DiaPep277: An exploratory study
-
DiaPep Trialists Group
-
R. Buzzetti, S. Cernea, A. Petrone, M. Capizzi, M. Spoletini, S. Zampetti, C. Guglielmi, C. Venditti, P. Pozzilli; DiaPep Trialists Group, C-peptide response and HLA genotypes in subjects with recent-onset type 1 diabetes after immunotherapy with DiaPep277: An exploratory study. Diabetes 60, 3067-3072 (2011).
-
(2011)
Diabetes
, vol.60
, pp. 3067-3072
-
-
Buzzetti, R.1
Cernea, S.2
Petrone, A.3
Capizzi, M.4
Spoletini, M.5
Zampetti, S.6
Guglielmi, C.7
Venditti, C.8
Pozzilli, P.9
-
45
-
-
0023143676
-
Antigen presentation by chemically modified splenocytes induces antigen-specific T cell unresponsiveness in vitro and in vivo
-
M. K. Jenkins, R. H. Schwartz, Antigen presentation by chemically modified splenocytes induces antigen-specific T cell unresponsiveness in vitro and in vivo. J. Exp. Med. 165, 302-319 (1987).
-
(1987)
J. Exp. Med.
, vol.165
, pp. 302-319
-
-
Jenkins, M.K.1
Schwartz, R.H.2
-
46
-
-
80052670800
-
+and IL-10-producing splenic macrophages and maintained by T regulatory cells
-
+ and IL-10-producing splenic macrophages and maintained by T regulatory cells. J. Immunol. 187, 2405-2417 (2011).
-
(2011)
J. Immunol.
, vol.187
, pp. 2405-2417
-
-
Getts, D.R.1
Turley, D.M.2
Smith, C.E.3
Harp, C.T.4
McCarthy, D.5
Feeney, E.M.6
Getts, M.T.7
Martin, A.J.8
Luo, X.9
Terry, R.L.10
King, N.J.C.11
Miller, S.D.12
-
47
-
-
80052772272
-
Opposing functions of IL-2 and IL-7 in the regulation of immune responses
-
S. D. Katzman, K. K. Hoyer, H. Dooms, I. K. Gratz, M. D. Rosenblum, J. S. Paw, S. H. Isakson, A. K. Abbas, Opposing functions of IL-2 and IL-7 in the regulation of immune responses. Cytokine 56, 116-121 (2011).
-
(2011)
Cytokine
, vol.56
, pp. 116-121
-
-
Katzman, S.D.1
Hoyer, K.K.2
Dooms, H.3
Gratz, I.K.4
Rosenblum, M.D.5
Paw, J.S.6
Isakson, S.H.7
Abbas, A.K.8
-
48
-
-
33645465526
-
Selective stimulation of T cell subsets with antibody-cytokine immune complexes
-
O. Boyman, M. Kovar, M. P. Rubinstein, C. D. Surh, J. Sprent, Selective stimulation of T cell subsets with antibody-cytokine immune complexes. Science 311, 1924-1927 (2006).
-
(2006)
Science
, vol.311
, pp. 1924-1927
-
-
Boyman, O.1
Kovar, M.2
Rubinstein, M.P.3
Surh, C.D.4
Sprent, J.5
-
49
-
-
33845339257
-
Potential use of IL-2/anti-IL-2 antibody immune complexes for the treatment of cancer and autoimmune disease
-
O. Boyman, C. D. Surh, J. Sprent, Potential use of IL-2/anti-IL-2 antibody immune complexes for the treatment of cancer and autoimmune disease. Expert Opin. Biol. Ther. 6, 1323-1331 (2006).
-
(2006)
Expert Opin. Biol. Ther.
, vol.6
, pp. 1323-1331
-
-
Boyman, O.1
Surh, C.D.2
Sprent, J.3
-
50
-
-
79961026869
-
In vivo expansion of regulatory T cells with IL-2/IL-2 mAb complexes prevents anti-factor VIII immune responses in hemophilia A mice treated with factor VIII plasmid-mediated gene therapy
-
C. L. Liu, P. Ye, B. C. Yen, C. H. Miao, In vivo expansion of regulatory T cells with IL-2/IL-2 mAb complexes prevents anti-factor VIII immune responses in hemophilia A mice treated with factor VIII plasmid-mediated gene therapy. Mol. Ther. 19, 1511-1520 (2011).
-
(2011)
Mol. Ther.
, vol.19
, pp. 1511-1520
-
-
Liu, C.L.1
Ye, P.2
Yen, B.C.3
Miao, C.H.4
-
51
-
-
77953297342
-
Expansion of regulatory T cells via IL-2/anti-IL-2 mAb complexes suppresses experimental myasthenia
-
R. Liu, Q. Zhou, A. La Cava, D. I. Campagnolo, L. Van Kaer, F. D. Shi, Expansion of regulatory T cells via IL-2/anti-IL-2 mAb complexes suppresses experimental myasthenia. Eur. J. Immunol. 40, 1577-1589 (2010).
-
(2010)
Eur. J. Immunol.
, vol.40
, pp. 1577-1589
-
-
Liu, R.1
Zhou, Q.2
La Cava, A.3
Campagnolo, D.I.4
Van Kaer, L.5
Shi, F.D.6
-
52
-
-
65549091509
-
In vivo expansion of T reg cells with IL-2-mAb complexes: Induction of resistance to EAE and long-term acceptance of islet allografts without immunosuppression
-
K. E. Webster, S. Walters, R. E. Kohler, T. Mrkvan, O. Boyman, C. D. Surh, S. T. Grey, J. Sprent, In vivo expansion of T reg cells with IL-2-mAb complexes: Induction of resistance to EAE and long-term acceptance of islet allografts without immunosuppression. J. Exp. Med. 206, 751-760 (2009).
-
(2009)
J. Exp. Med.
, vol.206
, pp. 751-760
-
-
Webster, K.E.1
Walters, S.2
Kohler, R.E.3
Mrkvan, T.4
Boyman, O.5
Surh, C.D.6
Grey, S.T.7
Sprent, J.8
-
53
-
-
43049174722
-
Central role of defective interleukin-2 production in the triggering of islet autoimmune destruction
-
Q. Tang, J. Y. Adams, C. Penaranda, K. Melli, E. Piaggio, E. Sgouroudis, C. A. Piccirillo, B. L. Salomon, J. A. Bluestone, Central role of defective interleukin-2 production in the triggering of islet autoimmune destruction. Immunity 28, 687-697 (2008).
-
(2008)
Immunity
, vol.28
, pp. 687-697
-
-
Tang, Q.1
Adams, J.Y.2
Penaranda, C.3
Melli, K.4
Piaggio, E.5
Sgouroudis, E.6
Piccirillo, C.A.7
Salomon, B.L.8
Bluestone, J.A.9
-
54
-
-
82555168440
-
Interleukin-2 and regulatory T cells in graft-versus-host disease
-
J. Koreth, K. Matsuoka, H. T. Kim, S. M. McDonough, B. Bindra, E. P. Alyea III, P. Armand, C. Cutler, V. T. Ho, N. S. Treister, D. C. Bienfang, S. Prasad, D. Tzachanis, R. M. Joyce, D. E. Avigan, J. H. Antin, J. Ritz, R. J. Soiffer, Interleukin-2 and regulatory T cells in graft-versus-host disease. N. Engl. J. Med. 365, 2055-2066 (2011).
-
(2011)
N. Engl. J. Med.
, vol.365
, pp. 2055-2066
-
-
Koreth, J.1
Matsuoka, K.2
Kim, H.T.3
McDonough, S.M.4
Bindra, B.5
Alyea III, E.P.6
Armand, P.7
Cutler, C.8
Ho, V.T.9
Treister, N.S.10
Bienfang, D.C.11
Prasad, S.12
Tzachanis, D.13
Joyce, R.M.14
Avigan, D.E.15
Antin, J.H.16
Ritz, J.17
Soiffer, R.J.18
-
55
-
-
84855810504
-
Discovery of T cell antigens by high-throughput screening of synthetic minigene libraries
-
B. D. Hondowicz, K. V. Schwedhelm, A. Kas, M. A. Tasch, C. Rawlings, N. Ramchurren, M. McIntosh, L. A. D'Amico, S. Sanda, N. E. Standifer, J. Shendure, B. Stone, Discovery of T cell antigens by high-throughput screening of synthetic minigene libraries. PLoS One 7, e29949 (2012).
-
(2012)
PLoS One
, vol.7
-
-
Hondowicz, B.D.1
Schwedhelm, K.V.2
Kas, A.3
Tasch, M.A.4
Rawlings, C.5
Ramchurren, N.6
McIntosh, M.7
D'Amico, L.A.8
Sanda, S.9
Standifer, N.E.10
Shendure, J.11
Stone, B.12
-
57
-
-
35349024802
-
CXCR3 signaling reduces the severity of experimental autoimmune encephalomyelitis by controlling the parenchymal distribution of effector and regulatory T cells in the central nervous system
-
M. Müller, S. L. Carter, M. J. Hofer, P. Manders, D. R. Getts, M. T. Getts, A. Dreykluft, B. Lu, C. Gerard, N. J. C. King, I. L. Campbell, CXCR3 signaling reduces the severity of experimental autoimmune encephalomyelitis by controlling the parenchymal distribution of effector and regulatory T cells in the central nervous system. J. Immunol. 179, 2774-2786 (2007).
-
(2007)
J. Immunol.
, vol.179
, pp. 2774-2786
-
-
Müller, M.1
Carter, S.L.2
Hofer, M.J.3
Manders, P.4
Getts, D.R.5
Getts, M.T.6
Dreykluft, A.7
Lu, B.8
Gerard, C.9
King, N.J.C.10
Campbell, I.L.11
-
60
-
-
80053571014
-
Sustained disease remission and inhibition of radiographic progression in methotrexate-naive patients with rheumatoid arthritis and poor prognostic factors treated with abatacept: 2-year outcomes
-
J. Bathon, M. Robles, A. C. Ximenes, S. Nayiager, J. Wollenhaupt, P. Durez, J. Gomez-Reino, W. Grassi, B. Haraoui, W. Shergy, S. H. Park, H. Genant, C. Peterfy, J. C. Becker, A. Covucci, D. Moniz Reed, R. Helfrick, R. Westhovens, Sustained disease remission and inhibition of radiographic progression in methotrexate-naive patients with rheumatoid arthritis and poor prognostic factors treated with abatacept: 2-year outcomes. Ann. Rheum. Dis. 70, 1949-1956 (2011).
-
(2011)
Ann. Rheum. Dis.
, vol.70
, pp. 1949-1956
-
-
Bathon, J.1
Robles, M.2
Ximenes, A.C.3
Nayiager, S.4
Wollenhaupt, J.5
Durez, P.6
Gomez-Reino, J.7
Grassi, W.8
Haraoui, B.9
Shergy, W.10
Park, S.H.11
Genant, H.12
Peterfy, C.13
Becker, J.C.14
Covucci, A.15
Moniz Reed, D.16
Helfrick, R.17
Westhovens, R.18
-
61
-
-
33748416499
-
Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412
-
G. Suntharalingam,M. R. Perry, S.Ward, S. J. Brett, A. Castello-Cortes, M. D. Brunner, N. Panoskaltsis, Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412. N. Engl. J. Med. 355, 1018-1028 (2006).
-
(2006)
N. Engl. J. Med.
, vol.355
, pp. 1018-1028
-
-
Suntharalingam, G.1
Perry, M.R.2
Ward, S.3
Brett, S.J.4
Castello-Cortes, A.5
Brunner, M.D.6
Panoskaltsis, N.7
-
62
-
-
0345107256
-
A novel targeted T-cell modulator, efalizumab, for plaque psoriasis
-
Efalizumab Study Group
-
M. Lebwohl, S. K. Tyring, T. K. Hamilton, D. Toth, S. Glazer, N. H. Tawfik, P. Walicke, W. Dummer, X. Wang, M. R. Garovoy, D. Pariser; Efalizumab Study Group, A novel targeted T-cell modulator, efalizumab, for plaque psoriasis. N. Engl. J. Med. 349, 2004-2013 (2003).
-
(2003)
N. Engl. J. Med.
, vol.349
, pp. 2004-2013
-
-
Lebwohl, M.1
Tyring, S.K.2
Hamilton, T.K.3
Toth, D.4
Glazer, S.5
Tawfik, N.H.6
Walicke, P.7
Dummer, W.8
Wang, X.9
Garovoy, M.R.10
Pariser, D.11
-
63
-
-
81255129068
-
Progressive multifocal leukoencephalopathy: An unexpected complication of modern therapeutic monoclonal antibody therapies
-
E. Tavazzi, P. Ferrante, K. Khalili, Progressive multifocal leukoencephalopathy: An unexpected complication of modern therapeutic monoclonal antibody therapies. Clin. Microbiol. Infect. 17, 1776-1780 (2011).
-
(2011)
Clin. Microbiol. Infect.
, vol.17
, pp. 1776-1780
-
-
Tavazzi, E.1
Ferrante, P.2
Khalili, K.3
-
64
-
-
0037333857
-
A short course of BG9588 (anti-CD40 ligand antibody) improves serologic activity and decreases hematuria in patients with proliferative lupus glomerulonephritis
-
BG9588 Lupus Nephritis Trial Group
-
D. T. Boumpas, R. Furie, S. Manzi, G. G. Illei, D. J. Wallace, J. E. Balow, A. Vaishnaw; BG9588 Lupus Nephritis Trial Group, A short course of BG9588 (anti-CD40 ligand antibody) improves serologic activity and decreases hematuria in patients with proliferative lupus glomerulonephritis. Arthritis Rheum. 48, 719-727 (2003).
-
(2003)
Arthritis Rheum
, vol.48
, pp. 719-727
-
-
Boumpas, D.T.1
Furie, R.2
Manzi, S.3
Illei, G.G.4
Wallace, D.J.5
Balow, J.E.6
Vaishnaw, A.7
-
65
-
-
70249122695
-
- T regulatory cells
-
- T regulatory cells. Clin. Immunol. 133, 22-26 (2009).
-
(2009)
Clin. Immunol.
, vol.133
, pp. 22-26
-
-
Trzonkowski, P.1
Bieniaszewska, M.2
Juścińska, J.3
Dobyszuk, A.4
Krzystyniak, A.5
Marek, N.6
Myśliwska, J.7
Hellmann, A.8
-
66
-
-
80053597291
-
Regulatory T cells in stem cell transplantation: Strategies and first clinical experiences
-
M. Edinger, P. Hoffmann, Regulatory T cells in stem cell transplantation: Strategies and first clinical experiences. Curr. Opin. Immunol. 23, 679-684 (2011).
-
(2011)
Curr. Opin. Immunol.
, vol.23
, pp. 679-684
-
-
Edinger, M.1
Hoffmann, P.2
-
67
-
-
79960743608
-
Antigen-based therapy with glutamic acid decarboxylase (GAD) vaccine in patients with recent-onset type 1 diabetes: A randomised double-blind trial
-
Type 1 Diabetes TrialNet GAD Study Group
-
D. K. Wherrett, B. Bundy, D. J. Becker, L. A. DiMeglio, S. E. Gitelman, R. Goland, P. A. Gottlieb, C. J. Greenbaum, K. C. Herold, J. B. Marks, R. Monzavi, A. Moran, T. Orban, J. P. Palmer, P. Raskin, H. Rodriguez, D. Schatz, D. M. Wilson, J. P. Krischer, J. S. Skyler; Type 1 Diabetes TrialNet GAD Study Group, Antigen-based therapy with glutamic acid decarboxylase (GAD) vaccine in patients with recent-onset type 1 diabetes: A randomised double-blind trial. Lancet 378, 319-327 (2011).
-
(2011)
Lancet
, vol.378
, pp. 319-327
-
-
Wherrett, D.K.1
Bundy, B.2
Becker, D.J.3
DiMeglio, L.A.4
Gitelman, S.E.5
Goland, R.6
Gottlieb, P.A.7
Greenbaum, C.J.8
Herold, K.C.9
Marks, J.B.10
Monzavi, R.11
Moran, A.12
Orban, T.13
Palmer, J.P.14
Raskin, P.15
Rodriguez, H.16
Schatz, D.17
Wilson, D.M.18
Krischer, J.P.19
Skyler, J.S.20
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