The roles of costimulation and Fas in T cell apoptosis and peripheral tolerance

Immunity

Volumn 4, Issue 3, 1996, Pages 321-328

  Van Parijs, Luk ^a   Ibraghimov, Alexander ^b   Abbas, Abul K ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD28 ANTIGEN; FAS ANTIGEN; INTERLEUKIN 2; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; FLOW CYTOMETRY; IMMUNOLOGICAL TOLERANCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE;

ANIMALS; ANTIGEN PRESENTATION; ANTIGENS, CD28; ANTIGENS, CD95; APOPTOSIS; CD4-POSITIVE T-LYMPHOCYTES; CLONAL DELETION; FAS LIGAND PROTEIN; GENE EXPRESSION REGULATION; IMMUNE TOLERANCE; LIGANDS; LYMPHOCYTE ACTIVATION; MEMBRANE GLYCOPROTEINS; MICE; MICE, TRANSGENIC; PROTO-ONCOGENES; SIGNAL TRANSDUCTION;

EID: 0029939945     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7613(00)80440-9     Document Type: Article

References (36)

1. Alderson, M.R., Armitage, R.J., Marashakovsky, E., Tough, T.W., Roux, E., Schooley, K., Ramsdell, F., and Lynch, D.H. (1993). Fas transduces activation signals in normal human T lymphocytes. J. Exp. Med. 178, 2231-2235.
2. Beutler, B., and van Huffel, C. (1994). Unraveling function in the TNF ligand and receptor families. Science 264, 667-668.
3. L. Immunity 3, 87-98.
4. Brunner, T., Mogil, R.J., LaFace, D., Yoo, N.J., Mahboubi, A., Echeverri, F., Martin, S.J., Force, W.R., Lynch, D.H., Ware, C.F., and Green, D.R. (1995). Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T cell hybridomas. Nature 373, 441-444.
5. Burstein, H.J., and Abbas, A.K. (1993). In vivo role of interleukin 4 in T cell tolerance induced by aqueous protein antigen. J. Exp. Med. 177, 457-463.
6. Burstein, H.J., Shea, C.M.,and Abbas, A.K. (1992). Aqueous antigens induce in vivo tolerance selectively In IL-2- and IFN-γ-producing (Th1) cells. J. Immunol. 148, 3687-3691.
7. Cohen, J.J., Duke, R.C., Fadok, V.A., and Sellins, K.S. (1992). Apoptosis and programmed cell death in immunity. Annu. Rev. Immunol. 10, 267-293.
8. De Wit, D., Van Mechelen, M., Ryelandt, M., Figueiredo, A.C., Abramowicz, D., Goldman, M., Bazin, H., Urbain, J., and Leo, O. (1992). The injection of deaggregated gamma globulins in adult mice induces antigen-specific unresponsiveness of T helper type 1 but not type 2 lymphocytes. J. Exp. Med. 175, 9-14.
9. Dhein, J., Walczak, H., Baumler, C., Debatin, K.-M., and Krammer, P.H. (1995). Autocrine T-cell suicide mediated by APO-1/(Fas/CD95). Nature. 373, 438-441.
10. Fang, W., Rivard, J.J., Mueller, D.L., and Behrens, T.W. (1994). Cloning and molecular characterization of mouse bcl-x in B and T lymphocytes. J. Immunol. 153, 4388-4398.
11. Fisher, G.H., Rosenberg, F.J., Straus, S.E., Dale, J.K., Middelton, L.A., Lin, A.Y., Strober, W., Lenardo, M.J., and Puck, J.M. (1995). Dominant interfering fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome. Cell 81, 935-946.
12. Green, D.R., and Scott, D.W. (1994). Activation-induced apoptosis in lymphocytes. Curr. Opin. Immunol. 6, 476-487.
13. Gribben, J.G., Freeman, G.J., Boussiotis, V.A., Rennert, P., Jellis, C.L., Greenfield, E., Barber, M., Restivo, V.A., Jr., Gray, G.S., and Nadler, L.M. (1995). CTLA4 mediates antigen specific apoptosis in T cells. Proc. Natl. Acad. Sci. USA 92, 811-815.
14. Ju, S.-T., Panka, D.J., Cui, H., Ettinger, R., El-Kharib, M., Sherr, D.H., Stanger, B.Z., and Marshak-Rothstein, A. (1995). Fas (CD95)/ FasL interactions required for programmed cell death after T-cell activation. Nature 373, 441-448.
15. June, C.H., Bluestone, J.A., Nadler, L.M., and Thompson, C.B. (1994). The B7 and CD28 receptor families. Immunol. Today. 15, 321-331.
16. Kearney, E.K., Pape, K.A., Loh, D.Y., and Jenkins, M.K. (1994). Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo. Immunity 1, 327-339.
17. + T cells in vivo is dependent on CD28 costimulation and inhibited by CTLA-4. J. Immunol. 155, 1032-1036.
18. Lenardo, M.J. (1991). Interleukin-2 programs mouse αβ T lymphocytes for apoptosis. Nature 353, 858-861.
19. Lucas, P.J., Negishi, I., Nakayama, K.-I., Fields, LE., and Loh, D.Y. (1995). Naive CD28-deficient T cells can initiate but not sustain an in vitro antigen-specific immune response. J. Immunol. 154, 5757-5768.
20. McKnight, A.J., Ferez, V.L., Shea, C.M., Fray, G.S., and Abbas, A.K. (1994). Costimulator dependence of lymphokine secretion by naive and activated CD4 T lymphocytes from TCR transgenic mice. J. Immunol. 152, 5220-5225.
21. Memon, S.A., Moreno, M.B., Petrak, D., and Zacharchuk, C.M. (1995). Bcl-2 blocks glucocorticoid-but not Fas-or activation-induced apoptosis in a T cell hybridoma. J. Immunol. 155, 4644-4652.
22. Miller, J.F.A.P., and Flavell, R.A. (1994). T-cell tolerance and autoimmunity in transgenic models of central and peripheral tolerance. Curr. Opin. Immunol. 6, 892-899.
23. Nagata, S., and Suda, T. (1995). Fas and fas ligand: Ipr and gld mutations. Immunol. Today. 16, 39-43.
24. Nunez, G., Merino, R., Grillot, D., and Gonzalez-Garcia, M. (1994). Bcl-2 and Bcl-x: regulatory switches for lymphoid death and survival. Immunol. Today 15, 582-588.
25. Prabhu Das, M.R., Zamvil, S.S., Borriello, F., Weiner, H.L, Sharpe, A.H., and Kuchroo, V.K. (1995). Reciprocal expression of co-stimulatory molecules, B7-1 and B7-2, on murine T cells following activation. Eur. J. Immunol. 25, 207-211.
26. + T cells by staphylococcal enterotoxin B. J. Exp. Med. 172, 1091-1100.
27. Rieux-Laucat, F., Le Deist, F., Hivroz, C., Roberts, I.A.G., Debatin, K.M., Fischer, A., and de Villartay, J.P. (1995). Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity. Science 268, 1347-1349.
28. Russell, J.H. (1995). Activation-induced death of mature T cells in the regulation of immune responses. Curr. Opin. Immunol. 7, 382-388.
29. Schwartz, R.H. (1990). A cell culture model for T lymphocyte clonal anergy. Science 248, 1349-1356.
30. Schwartz, R.H. (1992). Costimulation of T lymphocytes: the role of CD28, CTLA-4, and B7/BB1 in interleukin-2 production and immunotherapy. Cell 71, 1065-1068.
31. Singer, G.G., and Abbas, A.K. (1994). The fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice. Immunity 1, 365-371.
32. Steller, H. (1995). Mechanisms and genes of cellular suicide. Science 267, 1445-1449.
33. Strasser, A., Harris, A.W., Huang, D.C.S., Krammer, P.H., and Cory, S. (1996). Bcl-2 and Fas/Apo-1 regulate distinct pathways to lymphocyte apoptosis. EMBO J., in press.
34. Vidard, L., Colarusso, L.J., and Benacerraf, B. (1994). Specific T-cell tolerance may be proceeded by a primary response. Proc. Natl. Acad. Sci. USA 91, 5627-5631.
35. Willerford, D.M., Chen, J., Ferry, J.A., Ma, A., and Alt, F.W. (1995). Interleukin-2 receptor a chain regulates the size and content of the peripheral lymphoid compartment. Immunity 3, 521-530.
36. Yuh, K., Siminovitch, K.A., and Ochi, A. (1993). T cell anergy is programmed early after exposure to bacterial superantigen in vivo. Int. Immunol. 5, 1375-1382.