메뉴 건너뛰기




Volumn 125, Issue 3, 2009, Pages 556-564

Nmi (N-Myc interactor) inhibits Wnt/β-catenin signaling and retards tumor growth

Author keywords

Dkk1; Nmi; Tumorigenesis; Wnt

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; BETA CATENIN; CANCER ANTIBODY; DICKKOPF 1 PROTEIN; GAMMA INTERFERON; MYC PROTEIN; N MYC INTERACTOR PROTEIN; NUCLEAR PROTEIN; UNCLASSIFIED DRUG; WNT PROTEIN;

EID: 67650088521     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.24276     Document Type: Article
Times cited : (64)

References (55)
  • 1
    • 0029892570 scopus 로고    scopus 로고
    • Isolation and characterization of Nmi, a novel partner of Myc proteins
    • Bao J, Zervos AS. Isolation and characterization of Nmi, a novel partner of Myc proteins. Oncogene 1996;12:2171-6.
    • (1996) Oncogene , vol.12 , pp. 2171-2176
    • Bao, J.1    Zervos, A.S.2
  • 2
    • 0033581841 scopus 로고    scopus 로고
    • Nmi protein interacts with regions that differ between MycN and Myc and is localized in the cytoplasm of neuroblastoma cells in contrast to nuclear MycN
    • Bannasch D, Weis I, Schwab M. Nmi protein interacts with regions that differ between MycN and Myc and is localized in the cytoplasm of neuroblastoma cells in contrast to nuclear MycN. Oncogene 1999; 18:6810-7.
    • (1999) Oncogene , vol.18 , pp. 6810-6817
    • Bannasch, D.1    Weis, I.2    Schwab, M.3
  • 3
    • 0033551388 scopus 로고    scopus 로고
    • New Myc-interacting proteins: A second Myc network emerges
    • Sakamuro D, Prendergast GC. New Myc-interacting proteins: a second Myc network emerges. Oncogene 1999;18:2942-54.
    • (1999) Oncogene , vol.18 , pp. 2942-2954
    • Sakamuro, D.1    Prendergast, G.C.2
  • 4
    • 27144478022 scopus 로고    scopus 로고
    • The high-mobility group transcription factor Sox10 interacts with the N-myc-interacting protein Nmi
    • Schlierf B, Lang S, Kosian T, Werner T, Wegner M. The high-mobility group transcription factor Sox10 interacts with the N-myc-interacting protein Nmi. J Mol Biol 2005;353:1033-42.
    • (2005) J Mol Biol , vol.353 , pp. 1033-1042
    • Schlierf, B.1    Lang, S.2    Kosian, T.3    Werner, T.4    Wegner, M.5
  • 5
    • 0034680854 scopus 로고    scopus 로고
    • Interferon-inducible Myc/STAT-interacting protein Nmi associates with IFP 35 into a high molecular mass complex and inhibits proteasome-mediated degradation of IFP 35
    • Chen J, Shpall RL, Meyerdierks A, Hagemeier M, Bottger EC, Naumovski L. Interferon-inducible Myc/STAT-interacting protein Nmi associates with IFP 35 into a high molecular mass complex and inhibits proteasome-mediated degradation of IFP 35. J Biol Chem 2000; 275:36278-84.
    • (2000) J Biol Chem , vol.275 , pp. 36278-36284
    • Chen, J.1    Shpall, R.L.2    Meyerdierks, A.3    Hagemeier, M.4    Bottger, E.C.5    Naumovski, L.6
  • 6
    • 0032706379 scopus 로고    scopus 로고
    • Subcellular localization of interferon-inducible Myc/stat-interacting protein Nmi is regulated by a novel IFP 35 homologous domain
    • Lee ND, Chen J, Shpall RL, Naumovski L. Subcellular localization of interferon-inducible Myc/stat-interacting protein Nmi is regulated by a novel IFP 35 homologous domain. J Interferon Cytokine Res 1999; 19:1245-52.
    • (1999) J Interferon Cytokine Res , vol.19 , pp. 1245-1252
    • Lee, N.D.1    Chen, J.2    Shpall, R.L.3    Naumovski, L.4
  • 7
    • 0036395172 scopus 로고    scopus 로고
    • Identification of a protein interacting with apoptin from human leucocyte cDNA library by using yeast two-hybrid screening]
    • Sun GJ, Tong X, Dong Y, Mei ZZ, Sun ZX. [Identification of a protein interacting with apoptin from human leucocyte cDNA library by using yeast two-hybrid screening]. Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai) 2002;34:369-72.
    • (2002) Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai) , vol.34 , pp. 369-372
    • Sun, G.J.1    Tong, X.2    Dong, Y.3    Mei, Z.Z.4    Sun, Z.X.5
  • 8
    • 0033534562 scopus 로고    scopus 로고
    • Functional association of Nmi with Stat5 and Stat1 in IL-2- and IFNgamma-mediated signaling
    • Zhu M, John S, Berg M, Leonard WJ. Functional association of Nmi with Stat5 and Stat1 in IL-2- and IFNgamma-mediated signaling. Cell 1999;96:121-30.
    • (1999) Cell , vol.96 , pp. 121-130
    • Zhu, M.1    John, S.2    Berg, M.3    Leonard, W.J.4
  • 9
    • 0037036349 scopus 로고    scopus 로고
    • A novel tricomplex of BRCA1. Nmi, and c-Myc inhibits c-Myc-induced human telomerase reverse transcriptase gene (h. TERT) promoter activity in breast cancer
    • Li H, Lee TH, Avraham H. A novel tricomplex of BRCA1. Nmi, and c-Myc inhibits c-Myc-induced human telomerase reverse transcriptase gene (h. TERT) promoter activity in breast cancer. J Biol Chem 2002; 277:20965-73.
    • (2002) J Biol Chem , vol.277 , pp. 20965-20973
    • Li, H.1    Lee, T.H.2    Avraham, H.3
  • 11
    • 0035159881 scopus 로고    scopus 로고
    • Identification of novel deletion regions on chromosome arms 2q and 6p in breast carcinomas by amplotype analysis
    • Piao Z, Lee KS, Kim H, Perucho M, Malkhosyan S. Identification of novel deletion regions on chromosome arms 2q and 6p in breast carcinomas by amplotype analysis. Genes Chromosomes Cancer 2001;30: 113-22.
    • (2001) Genes Chromosomes Cancer , vol.30 , pp. 113-122
    • Piao, Z.1    Lee, K.S.2    Kim, H.3    Perucho, M.4    Malkhosyan, S.5
  • 12
    • 0842266786 scopus 로고    scopus 로고
    • Interferon-gamma: An overview of signals, mechanisms and functions
    • Schroder K, Hertzog PJ, Ravasi T, Hume DA. Interferon-gamma: an overview of signals, mechanisms and functions. J Leukoc Biol 2004; 75:163-89.
    • (2004) J Leukoc Biol , vol.75 , pp. 163-189
    • Schroder, K.1    Hertzog, P.J.2    Ravasi, T.3    Hume, D.A.4
  • 13
    • 18844457095 scopus 로고    scopus 로고
    • Mechanisms of type-I- and type-II-interferon-mediated signalling
    • Platanias LC. Mechanisms of type-I- and type-II-interferon-mediated signalling. Nat Rev Immunol 2005;5:375-86.
    • (2005) Nat Rev Immunol , vol.5 , pp. 375-386
    • Platanias, L.C.1
  • 15
    • 34447530928 scopus 로고    scopus 로고
    • c-Myc transforms human mammary epithelial cells through repression of the Wnt inhibitors DKK1 and SFRP1
    • Cowling VH, D'Cruz CM, Chodosh LA, Cole MD. c-Myc transforms human mammary epithelial cells through repression of the Wnt inhibitors DKK1 and SFRP1. Mol Cell Biol 2007;27:5135-46.
    • (2007) Mol Cell Biol , vol.27 , pp. 5135-5146
    • Cowling, V.H.1    D'Cruz, C.M.2    Chodosh, L.A.3    Cole, M.D.4
  • 17
    • 34250869019 scopus 로고    scopus 로고
    • MDAMB-435 cells are derived from M14 melanoma cells-a loss for breast cancer, but a boon for melanoma research
    • Rae JM, Creighton CJ, Meck JM, Haddad BR, Johnson MD. MDAMB-435 cells are derived from M14 melanoma cells-a loss for breast cancer, but a boon for melanoma research. Breast Cancer Res Treat 2007;104:13-9.
    • (2007) Breast Cancer Res Treat , vol.104 , pp. 13-19
    • Rae, J.M.1    Creighton, C.J.2    Meck, J.M.3    Haddad, B.R.4    Johnson, M.D.5
  • 19
    • 0026562946 scopus 로고
    • Comparative studies between nude and scid mice on the growth and metastatic behavior of xenografted human tumors
    • Xie X, Brunner N, Jensen G, Albrectsen J, Gotthardsen B, Rygaard J. Comparative studies between nude and scid mice on the growth and metastatic behavior of xenografted human tumors. Clin Exp Metastasis 1992;10:201-10.
    • (1992) Clin Exp Metastasis , vol.10 , pp. 201-210
    • Xie, X.1    Brunner, N.2    Jensen, G.3    Albrectsen, J.4    Gotthardsen, B.5    Rygaard, J.6
  • 20
    • 0034534734 scopus 로고    scopus 로고
    • Progression of premalignant MCF10AT generates heterogeneous malignant variants with characteristic histologic types and immunohistochemical markers
    • Strickland LB, Dawson PJ, Santner SJ, Miller FR. Progression of premalignant MCF10AT generates heterogeneous malignant variants with characteristic histologic types and immunohistochemical markers. Breast Cancer Res Treat 2000;64:235-40.
    • (2000) Breast Cancer Res Treat , vol.64 , pp. 235-240
    • Strickland, L.B.1    Dawson, P.J.2    Santner, S.J.3    Miller, F.R.4
  • 23
    • 0034686626 scopus 로고    scopus 로고
    • MCF10DCIS.com xenograft model of human comedo ductal carcinoma in situ
    • Miller FR, Santner SJ, Tait L, Dawson PJ. MCF10DCIS.com xenograft model of human comedo ductal carcinoma in situ. J Natl Cancer Inst 2000;92:1185-6.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 1185-1186
    • Miller, F.R.1    Santner, S.J.2    Tait, L.3    Dawson, P.J.4
  • 24
    • 13244299109 scopus 로고    scopus 로고
    • FGF-20 and DKK1 are transcriptional targets of beta-catenin and FGF-20 is implicated in cancer and development
    • Chamorro MN, Schwartz DR, Vonica A, Brivanlou AH, Cho KR, Varmus HE. FGF-20 and DKK1 are transcriptional targets of beta-catenin and FGF-20 is implicated in cancer and development. Embo J 2005;24:73-84.
    • (2005) Embo J , vol.24 , pp. 73-84
    • Chamorro, M.N.1    Schwartz, D.R.2    Vonica, A.3    Brivanlou, A.H.4    Cho, K.R.5    Varmus, H.E.6
  • 25
    • 25444469884 scopus 로고    scopus 로고
    • Gene expression changes and signaling events associated with the direct antimelanoma effect of IFN-gamma
    • Gollob JA, Sciambi CJ, Huang Z, Dressman HK. Gene expression changes and signaling events associated with the direct antimelanoma effect of IFN-gamma. Cancer Res 2005;65:8869-77.
    • (2005) Cancer Res , vol.65 , pp. 8869-8877
    • Gollob, J.A.1    Sciambi, C.J.2    Huang, Z.3    Dressman, H.K.4
  • 26
    • 0035822594 scopus 로고    scopus 로고
    • Wnt signalling: Antagonistic Dickkopfs
    • Zorn AM. Wnt signalling: antagonistic Dickkopfs. Curr Biol 2001;11: R592-5
    • (2001) Curr Biol , vol.11
    • Zorn, A.M.1
  • 27
    • 33845359084 scopus 로고    scopus 로고
    • Function and biological roles of the Dickkopf family of Wnt modulators
    • Niehrs C. Function and biological roles of the Dickkopf family of Wnt modulators. Oncogene 2006;25:7469-81.
    • (2006) Oncogene , vol.25 , pp. 7469-7481
    • Niehrs, C.1
  • 29
    • 33746808398 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling in development and disease
    • Clevers H. Wnt/beta-catenin signaling in development and disease. Cell 2006;127:469-80.
    • (2006) Cell , vol.127 , pp. 469-480
    • Clevers, H.1
  • 30
    • 35648949978 scopus 로고    scopus 로고
    • beta-Catenin signaling in biological control and cancer
    • Gavert N, Ben-Ze'ev A. beta-Catenin signaling in biological control and cancer. J Cell Biochem 2007;102:820-8.
    • (2007) J Cell Biochem , vol.102 , pp. 820-828
    • Gavert, N.1    Ben-Ze'ev, A.2
  • 31
    • 0038783316 scopus 로고    scopus 로고
    • Secreted antagonists of the Wnt signalling pathway
    • Kawano Y, Kypta R. Secreted antagonists of the Wnt signalling pathway. J Cell Sci 2003;116:2627-34.
    • (2003) J Cell Sci , vol.116 , pp. 2627-2634
    • Kawano, Y.1    Kypta, R.2
  • 36
    • 30544447981 scopus 로고    scopus 로고
    • Transcriptional silencing of secreted frizzled related protein 1 (SFRP 1) by promoter hypermethylation in non-small-cell lung cancer
    • Fukui T, Kondo M, Ito G, Maeda O, Sato N, Yoshioka H, Yokoi K, Ueda Y, Shimokata K, Sekido Y. Transcriptional silencing of secreted frizzled related protein 1 (SFRP 1) by promoter hypermethylation in non-small-cell lung cancer. Oncogene 2005;24:6323-7.
    • (2005) Oncogene , vol.24 , pp. 6323-6327
    • Fukui, T.1    Kondo, M.2    Ito, G.3    Maeda, O.4    Sato, N.5    Yoshioka, H.6    Yokoi, K.7    Ueda, Y.8    Shimokata, K.9    Sekido, Y.10
  • 38
    • 47249164378 scopus 로고    scopus 로고
    • Epigenetic inactivation of the Secreted frizzled-related protein-5 (SFRP5) gene in human breast cancer is associated with unfavorable prognosis
    • Veeck J, Geisler C, Noetzel E, Alkaya S, Hartmann A, Knuchel R, Dahl E. Epigenetic inactivation of the Secreted frizzled-related protein-5 (SFRP5) gene in human breast cancer is associated with unfavorable prognosis. Carcinogenesis 2008;29:991-8.
    • (2008) Carcinogenesis , vol.29 , pp. 991-998
    • Veeck, J.1    Geisler, C.2    Noetzel, E.3    Alkaya, S.4    Hartmann, A.5    Knuchel, R.6    Dahl, E.7
  • 39
    • 7944230668 scopus 로고    scopus 로고
    • An autocrine mechanism for constitutive Wnt pathway activation in human cancer cells
    • Bafico A, Liu G, Goldin L, Harris V, Aaronson SA. An autocrine mechanism for constitutive Wnt pathway activation in human cancer cells. Cancer Cell 2004;6:497-506.
    • (2004) Cancer Cell , vol.6 , pp. 497-506
    • Bafico, A.1    Liu, G.2    Goldin, L.3    Harris, V.4    Aaronson, S.A.5
  • 40
    • 0037778008 scopus 로고    scopus 로고
    • The Wnt signaling pathway and its role in tumor development
    • Lustig B, Behrens J. The Wnt signaling pathway and its role in tumor development. J Cancer Res Clin Oncol 2003;129:199-221.
    • (2003) J Cancer Res Clin Oncol , vol.129 , pp. 199-221
    • Lustig, B.1    Behrens, J.2
  • 41
    • 85047699343 scopus 로고    scopus 로고
    • Human Dkk-1, a gene encoding a Wnt antagonist, responds to DNA damage and its overexpression sensitizes brain tumor cells to apoptosis following alkylation damage of DNA
    • Shou J, Ali-Osman F, Multani AS, Pathak S, Fedi P, Srivenugopal KS. Human Dkk-1, a gene encoding a Wnt antagonist, responds to DNA damage and its overexpression sensitizes brain tumor cells to apoptosis following alkylation damage of DNA. Oncogene 2002;21:878-89.
    • (2002) Oncogene , vol.21 , pp. 878-889
    • Shou, J.1    Ali-Osman, F.2    Multani, A.S.3    Pathak, S.4    Fedi, P.5    Srivenugopal, K.S.6
  • 42
    • 0035719960 scopus 로고    scopus 로고
    • Wnt signaling in breast cancer: Have we come full circle?
    • Brown AM. Wnt signaling in breast cancer: have we come full circle? Breast Cancer Res 2001;3:351-5.
    • (2001) Breast Cancer Res , vol.3 , pp. 351-355
    • Brown, A.M.1
  • 43
    • 41549152176 scopus 로고    scopus 로고
    • Wnt signaling pathway in invasive ductal carcinoma of the breast: Relationship between beta-catenin, dishevelled and cyclin D1 expression
    • Prasad CP, Gupta SD, Rath G, Ralhan R. Wnt signaling pathway in invasive ductal carcinoma of the breast: relationship between beta-catenin, dishevelled and cyclin D1 expression. Oncology 2007;73:112-7.
    • (2007) Oncology , vol.73 , pp. 112-117
    • Prasad, C.P.1    Gupta, S.D.2    Rath, G.3    Ralhan, R.4
  • 44
    • 0036005884 scopus 로고    scopus 로고
    • The roles of IFN gamma in protection against tumor development and cancer immunoediting
    • Ikeda H, Old LJ, Schreiber RD. The roles of IFN gamma in protection against tumor development and cancer immunoediting. Cytokine Growth Factor Rev 2002;13:95-109.
    • (2002) Cytokine Growth Factor Rev , vol.13 , pp. 95-109
    • Ikeda, H.1    Old, L.J.2    Schreiber, R.D.3
  • 45
    • 42349113210 scopus 로고    scopus 로고
    • The functions and possible significance of Kremen as the gatekeeper of Wnt signalling in development and pathology
    • Nakamura T, Matsumoto K. The functions and possible significance of Kremen as the gatekeeper of Wnt signalling in development and pathology. J Cell Mol Med 2008;12:391-408.
    • (2008) J Cell Mol Med , vol.12 , pp. 391-408
    • Nakamura, T.1    Matsumoto, K.2
  • 47
    • 0035939818 scopus 로고    scopus 로고
    • Beta-catenin is a downstream effector of Wnt-mediated tumorigenesis in the mammary gland
    • Michaelson JS, Leder P. Beta-catenin is a downstream effector of Wnt-mediated tumorigenesis in the mammary gland. Oncogene 2001; 20:5093-9.
    • (2001) Oncogene , vol.20 , pp. 5093-5099
    • Michaelson, J.S.1    Leder, P.2
  • 48
    • 0033513071 scopus 로고    scopus 로고
    • Activation and repression of wingless/Wnt target genes by the TCF/LEF-1 family of transcription factors
    • Korswagen HC, Clevers HC. Activation and repression of wingless/Wnt target genes by the TCF/LEF-1 family of transcription factors. Cold Spring Harb Symp Quant Biol 1999;64:141-7.
    • (1999) Cold Spring Harb Symp Quant Biol , vol.64 , pp. 141-147
    • Korswagen, H.C.1    Clevers, H.C.2
  • 51
    • 36849033467 scopus 로고    scopus 로고
    • Turning the tables: Myc activates Wnt in breast cancer
    • Cowling VH, Cole MD. Turning the tables: Myc activates Wnt in breast cancer. Cell Cycle 2007;6:2625-7.
    • (2007) Cell Cycle , vol.6 , pp. 2625-2627
    • Cowling, V.H.1    Cole, M.D.2
  • 53
    • 0037994177 scopus 로고    scopus 로고
    • Genetic background is an important determinant of metastatic potential
    • author reply 25
    • Hunter K, Welch DR, Liu ET. Genetic background is an important determinant of metastatic potential. Nat Genet 2003;34:23-4; author reply 25.
    • (2003) Nat Genet , vol.34 , pp. 23-24
    • Hunter, K.1    Welch, D.R.2    Liu, E.T.3
  • 54
    • 0242285692 scopus 로고    scopus 로고
    • TGF-beta switches from tumor suppressor to prometastatic factor in a model of breast cancer progression
    • Tang B, Vu M, Booker T, Santner SJ, Miller FR, Anver MR, Wakefield LM. TGF-beta switches from tumor suppressor to prometastatic factor in a model of breast cancer progression. J Clin Invest 2003;112: 1116-24.
    • (2003) J Clin Invest , vol.112 , pp. 1116-1124
    • Tang, B.1    Vu, M.2    Booker, T.3    Santner, S.J.4    Miller, F.R.5    Anver, M.R.6    Wakefield, L.M.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.