-
1
-
-
0028097617
-
A centrally active drug that modulates AMPA receptor gated currents
-
Arai, A., Kessler, M., Xiao, P., Ambros-Ingerson, J., Rogers, G. and Lynch, G.A. (1994) ‘A centrally active drug that modulates AMPA receptor gated currents’, Brain Res. 638: 343-346.
-
(1994)
Brain Res
, vol.638
, pp. 343-346
-
-
Arai, A.1
Kessler, M.2
Xiao, P.3
Ambros-Ingerson, J.4
Rogers, G.5
Lynch, G.A.6
-
2
-
-
0032578635
-
Structure of a glutamate-receptor ligand-binding core in complex with kainate
-
Armstrong, N., Sun, Y., Chen, G.-Q. and Gouaux, E. (1998) ‘Structure of a glutamate-receptor ligand-binding core in complex with kainate’, Nature 395: 913-917.
-
(1998)
Nature
, vol.395
, pp. 913-917
-
-
Armstrong, N.1
Sun, Y.2
Chen, G.-Q.3
Gouaux, E.4
-
3
-
-
0028800039
-
Differentiation of in vivo effects of AMPA and NMDA receptor ligands using drug discrimination methods and convulsant/anticonvulsant activity
-
Arnt, J., Sánchez, C., Lenz, S.M., Madsen, U. and Krogsgaard-Larsen, P. (1995) ‘Differentiation of in vivo effects of AMPA and NMDA receptor ligands using drug discrimination methods and convulsant/anticonvulsant activity’, Eur. J. Pharmacol. 285: 289-297.
-
(1995)
Eur. J. Pharmacol
, vol.285
, pp. 289-297
-
-
Arnt, J.1
Sánchez, C.2
Lenz, S.M.3
Madsen, U.4
Krogsgaard-Larsen, P.5
-
4
-
-
0030820888
-
Heteroaryl analogues of AMPA. Synthesis and quantitative structure-activity relationships
-
Bang-Andersen, B., Lenz, S.M., Skjærbæk, N., Søby, K.K., Hansen, H.O., Ebert, B., Bøgesø, K.P. and Krogsgaard-Larsen, P. (1997) ‘Heteroaryl analogues of AMPA. Synthesis and quantitative structure-activity relationships’, J. Med. Chem. 40: 2831-2842.
-
(1997)
J. Med. Chem
, vol.40
, pp. 2831-2842
-
-
Bang-Andersen, B.1
Lenz, S.M.2
Skjærbæk, N.3
Søby, K.K.4
Hansen, H.O.5
Ebert, B.6
Bøgesø, K.P.7
Krogsgaard-Larsen, P.8
-
5
-
-
0033010020
-
Novel potent AMPA analogues differentially affect desensitisation of AMPA receptors in cultured hippocampal neurons
-
Banke, T.G. and Lambert, J.D.C. (1999) ‘Novel potent AMPA analogues differentially affect desensitisation of AMPA receptors in cultured hippocampal neurons’, Eur. J. Pharmacol. 367: 405-412.
-
(1999)
Eur. J. Pharmacol
, vol.367
, pp. 405-412
-
-
Banke, T.G.1
Lambert, J.D.C.2
-
6
-
-
0029043312
-
Excitatory amino acid receptor ligands: Asymmetric synthesis, absolute stereochemistry and pharmacology of (R)- and (S)-homoibotenic acid
-
Bischoff, F., Johansen, T.N., Ebert, B., Krogsgaard-Larsen, P. and Madsen, U. (1995) ‘Excitatory amino acid receptor ligands: asymmetric synthesis, absolute stereochemistry and pharmacology of (R)- and (S)-homoibotenic acid’, Bioorg. Med. Chem. 3: 553-558.
-
(1995)
Bioorg. Med. Chem
, vol.3
, pp. 553-558
-
-
Bischoff, F.1
Johansen, T.N.2
Ebert, B.3
Krogsgaard-Larsen, P.4
Madsen, U.5
-
7
-
-
0029979667
-
Pharmacological discrimination of GluR5 and GluR6 kainate receptor subtypes by (3S,4aR,6R,8aR)-6-[2-(1(2)H-tetrazole-5-yl)ethyl]decahydroisoquinoline-3-carboxylic acid
-
Bleakman, D., Schoepp, D.D., Ballyk, B., Bufton, H., Sharpe, E.F., Thomas, K., Ornstein, P.L. and Kamboj, R.K. (1996) ‘Pharmacological discrimination of GluR5 and GluR6 kainate receptor subtypes by (3S,4aR,6R,8aR)-6-[2-(1(2)H-tetrazole-5-yl)ethyl]decahydroisoquinoline-3-carboxylic acid’, Mol. Pharmacol. 49: 581-585.
-
(1996)
Mol. Pharmacol
, vol.49
, pp. 581-585
-
-
Bleakman, D.1
Schoepp, D.D.2
Ballyk, B.3
Bufton, H.4
Sharpe, E.F.5
Thomas, K.6
Ornstein, P.L.7
Kamboj, R.K.8
-
8
-
-
0027196057
-
Thiocyanate ions selectively antagonize AMPA-evoked responses in Xenopus laevis oocytes microinjected with rat brain mRNA
-
Bowie, D. and Smart, T.G. (1993) ‘Thiocyanate ions selectively antagonize AMPA-evoked responses in Xenopus laevis oocytes microinjected with rat brain mRNA’, Br. J. Pharmacol. 109: 779-787.
-
(1993)
Br. J. Pharmacol
, vol.109
, pp. 779-787
-
-
Bowie, D.1
Smart, T.G.2
-
9
-
-
0029742345
-
A new highly selective metabotropic excitatory amino acid agonist: 2-amino-4-(3-hydroxy-5-methyl-4-yl)butyric acid
-
Bräuner-Osborne, H., Sløk, F.A., Skjærbæk, N., Ebert, B., Sekiyama, N., Nakanishi, S. and Krogsgaard-Larsen, P. (1996) ‘A new highly selective metabotropic excitatory amino acid agonist: 2-amino-4-(3-hydroxy-5-methyl-4-yl)butyric acid’, J. Med. Chem. 39: 3188-3194.
-
(1996)
J. Med. Chem
, vol.39
, pp. 3188-3194
-
-
Bräuner-Osborne, H.1
Sløk, F.A.2
Skjærbæk, N.3
Ebert, B.4
Sekiyama, N.5
Nakanishi, S.6
Krogsgaard-Larsen, P.7
-
10
-
-
0343907173
-
Molecular pharmacology of 4-substituted glutamic acid analogues at ionotropic and metabotropic excitatory amino acid receptors
-
Bräuner-Osborne, H., Nielsen, B., Stensbøl, T.B., Johansen, T.N., Skjærbæk, N. and Krogsgaard-Larsen, P. (1997) ‘Molecular pharmacology of 4-substituted glutamic acid analogues at ionotropic and metabotropic excitatory amino acid receptors’, Eur. J. Pharmacol. 335: R1-3.
-
(1997)
Eur. J. Pharmacol
, vol.335
, pp. R1-R3
-
-
Bräuner-Osborne, H.1
Nielsen, B.2
Stensbøl, T.B.3
Johansen, T.N.4
Skjærbæk, N.5
Krogsgaard-Larsen, P.6
-
11
-
-
0042683081
-
Molecular pharmacology of homologues of ibotenic acid at cloned metabotropic glutamic acid receptors
-
Bräuner-Osborne, H., Nielsen, B. and Krogsgaard-Larsen, P. (1998) ‘Molecular pharmacology of homologues of ibotenic acid at cloned metabotropic glutamic acid receptors’, Eur. J. Pharmacol. 350: 311-316.
-
(1998)
Eur. J. Pharmacol
, vol.350
, pp. 311-316
-
-
Bräuner-Osborne, H.1
Nielsen, B.2
Krogsgaard-Larsen, P.3
-
12
-
-
0032572821
-
'3,5-Dihydro-4H-2,3-benzodiazepine-4-thiones: A new class of AMPA receptor antagonists’
-
Chimirri, A., DeSarro, G., DeSarro, A., Gitto, R., Quartarone, S., Zappala, M., Constanti, A. and Libri, V. (1998) '3,5-Dihydro-4H-2,3-benzodiazepine-4-thiones: a new class of AMPA receptor antagonists’, J. Med. Chem. 41: 3409-3416.
-
(1998)
J. Med. Chem
, vol.41
, pp. 3409-3416
-
-
Chimirri, A.1
DeSarro, G.2
DeSarro, A.3
Gitto, R.4
Quartarone, S.5
Zappala, M.6
Constanti, A.7
Libri, V.8
-
13
-
-
0024849550
-
Excitatory amino acid agonists and partial agonists
-
Christensen, I.T., Reinhardt, A., Nielsen, B., Ebert, B., Madsen, U., Nielsen, E.Ø., Brehm, L. and Krogsgaard-Larsen, P. (1989) ‘Excitatory amino acid agonists and partial agonists’, Drug Des. Del. 5: 57-71.
-
(1989)
Drug Des. Del
, vol.5
, pp. 57-71
-
-
Christensen, I.T.1
Reinhardt, A.2
Nielsen, B.3
Ebert, B.4
Madsen, U.5
Nielsen, E.Ø.6
Brehm, L.7
Krogsgaard-Larsen, P.8
-
14
-
-
0026649570
-
Excitatory amino acid receptor ligands. Synthesis and biological activity of 3-isoxazolol amino acids structurally related to homoibotenic acid
-
Christensen, I.T., Ebert, B., Madsen, U., Nielsen, B., Brehm, L. and Krogsgaard-Larsen, P. (1992) ‘Excitatory amino acid receptor ligands. Synthesis and biological activity of 3-isoxazolol amino acids structurally related to homoibotenic acid’, J. Med. Chem. 35: 3512-3519.
-
(1992)
J. Med. Chem
, vol.35
, pp. 3512-3519
-
-
Christensen, I.T.1
Ebert, B.2
Madsen, U.3
Nielsen, B.4
Brehm, L.5
Krogsgaard-Larsen, P.6
-
15
-
-
0030863091
-
A hippocampal GluR5 kainate receptor regulating inhibitory synaptic transmission
-
Clarke, V.R.J., Ballyk, B.A., Hoo, K.H., Mandelzys, A., Pellizzari, A., Bath, C.P., Thomas, J., Sharpe, E.F., Davies, C.H., Ornstein, P.L., Schoepp, D.D., Kamboj, R.K., Collingridge, G.L., Lodge, D. and Bleakman, D. (1997) ‘A hippocampal GluR5 kainate receptor regulating inhibitory synaptic transmission’, Nature 389: 599-603.
-
(1997)
Nature
, vol.389
, pp. 599-603
-
-
Clarke, V.R.J.1
Ballyk, B.A.2
Hoo, K.H.3
Mandelzys, A.4
Pellizzari, A.5
Bath, C.P.6
Thomas, J.7
Sharpe, E.F.8
Davies, C.H.9
Ornstein, P.L.10
Schoepp, D.D.11
Kamboj, R.K.12
Collingridge, G.L.13
Lodge, D.14
Bleakman, D.15
-
16
-
-
0000439129
-
Excitatory amino acid receptors in the vertebrate central nervous system
-
Collingridge, G.L. and Lester, R.A.S. (1989) ‘Excitatory amino acid receptors in the vertebrate central nervous system’, Pharmacol. Rev. 40: 145-195.
-
(1989)
Pharmacol. Rev
, vol.40
, pp. 145-195
-
-
Collingridge, G.L.1
Lester, R.A.S.2
-
17
-
-
0028809208
-
Cyclothiazide acts at a site on the α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor complex that does not recognize competitive or noncompetitive AMPA receptor antagonists
-
Desai, M.A., Burnett, J.P., Ornstein, P.L. and Schoepp, D.D. (1995) ‘Cyclothiazide acts at a site on the α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor complex that does not recognize competitive or noncompetitive AMPA receptor antagonists’, J. Pharmacol. Exp. Ther. 272: 38-43.
-
(1995)
J. Pharmacol. Exp. Ther
, vol.272
, pp. 38-43
-
-
Desai, M.A.1
Burnett, J.P.2
Ornstein, P.L.3
Schoepp, D.D.4
-
18
-
-
0027404879
-
GYKI 52466, a 2,3-benzodiazepine, is a highly selective, noncompetitive antagonist of AMPA/kainate receptor responses
-
Donevan, S.D. and Rogawski, M.A. (1993) ‘GYKI 52466, a 2,3-benzodiazepine, is a highly selective, noncompetitive antagonist of AMPA/kainate receptor responses’, Neuron 10: 51-59.
-
(1993)
Neuron
, vol.10
, pp. 51-59
-
-
Donevan, S.D.1
Rogawski, M.A.2
-
19
-
-
0032483107
-
Allosteric regulation of α-amino-3-hydroxy-5-methyl-4-isoxazole-propionate receptors by thiocyanate and cyclothiazide at a common modulatory site distinct from that of 2,3-benzodiazepines
-
Donevan, S.D. and Rogawski, M.A. (1998) ‘Allosteric regulation of α-amino-3-hydroxy-5-methyl-4-isoxazole-propionate receptors by thiocyanate and cyclothiazide at a common modulatory site distinct from that of 2,3-benzodiazepines’, Neuroscience 87: 615-629.
-
(1998)
Neuroscience
, vol.87
, pp. 615-629
-
-
Donevan, S.D.1
Rogawski, M.A.2
-
20
-
-
0031836732
-
The methylglutamate, SYM 2081, is a potent and highly selective agonist at kainate receptors
-
Donevan, S.D., Beg, A., Gunther, J.M. and Twyman, R.E. (1998) ‘The methylglutamate, SYM 2081, is a potent and highly selective agonist at kainate receptors’, J. Pharmacol. Exp. Ther. 285: 539-545.
-
(1998)
J. Pharmacol. Exp. Ther
, vol.285
, pp. 539-545
-
-
Donevan, S.D.1
Beg, A.2
Gunther, J.M.3
Twyman, R.E.4
-
21
-
-
0026634107
-
Molecular pharmacology of cortical and spinal AMPA receptors
-
Ebert, B., Madsen, U., Lund, T.M., Holm, T. and Krogsgaard-Larsen, P. (1992) ‘Molecular pharmacology of cortical and spinal AMPA receptors’, Mol. Neuropharmacol. 2: 47-49.
-
(1992)
Mol. Neuropharmacol
, vol.2
, pp. 47-49
-
-
Ebert, B.1
Madsen, U.2
Lund, T.M.3
Holm, T.4
Krogsgaard-Larsen, P.5
-
22
-
-
0028202566
-
Resolution, absolute stereochemistry, and pharmacology of the (S)-(+)- and (R)-(-)-isomers of the apparent partial AMPA receptor agonist (R, S)-2-amino-3-(3-hydroxy-5-phenylisoxazol-4-yl)propionic acid [(R, S)-APPA]
-
Ebert, B., Lenz, S., Brehm, L., Bregnedal, P., Hansen, J.J., Frederiksen, K., Bøgesø, K.P. and Krogsgaard-Larsen, P. (1994a) ‘Resolution, absolute stereochemistry, and pharmacology of the (S)-(+)- and (R)-(-)-isomers of the apparent partial AMPA receptor agonist (R, S)-2-amino-3-(3-hydroxy-5-phenylisoxazol-4-yl)propionic acid [(R, S)-APPA]’, J. Med. Chem. 37: 878-884.
-
(1994)
J. Med. Chem
, vol.37
, pp. 878-884
-
-
Ebert, B.1
Lenz, S.2
Brehm, L.3
Bregnedal, P.4
Hansen, J.J.5
Frederiksen, K.6
Bøgesø, K.P.7
Krogsgaard-Larsen, P.8
-
23
-
-
0028272399
-
Molecular pharmacology of the AMPA agonist (S)-2-amino-3-(3-hydroxy-5-phenyl-4-isoxazolyl)propionic acid [(S)-APPA] and the AMPA antagonist, (R)-APPA
-
Ebert, B., Madsen, U., Lund, T.M., Lenz, S.M. and Krogsgaard-Larsen, P. (1994b) ‘Molecular pharmacology of the AMPA agonist (S)-2-amino-3-(3-hydroxy-5-phenyl-4-isoxazolyl)propionic acid [(S)-APPA] and the AMPA antagonist, (R)-APPA’, Neurochem. Int. 24: 507-515.
-
(1994)
Neurochem. Int
, vol.24
, pp. 507-515
-
-
Ebert, B.1
Madsen, U.2
Lund, T.M.3
Lenz, S.M.4
Krogsgaard-Larsen, P.5
-
24
-
-
0025765017
-
Cloning of a cDNA for a glutamate receptor subunit activated by kainate but not AMPA
-
Egebjerg, J., Bettler, B., Hermans, B.I. and Heinemann, S. (1991) ‘Cloning of a cDNA for a glutamate receptor subunit activated by kainate but not AMPA’, Nature 351: 745-748.
-
(1991)
Nature
, vol.351
, pp. 745-748
-
-
Egebjerg, J.1
Bettler, B.2
Hermans, B.I.3
Heinemann, S.4
-
25
-
-
0029742385
-
Thiocyanate ions inhibit AMPA-activated currents in recombinant non-NMDA receptors expressed in Xenopus laevis oocytes: The role of the GluR2 subunit
-
Eugene, D., Moss, S.J. and Smart, T.G. (1996) ‘Thiocyanate ions inhibit AMPA-activated currents in recombinant non-NMDA receptors expressed in Xenopus laevis oocytes: the role of the GluR2 subunit’, Eur. J. Neurosci. 8: 1983-1993.
-
(1996)
Eur. J. Neurosci
, vol.8
, pp. 1983-1993
-
-
Eugene, D.1
Moss, S.J.2
Smart, T.G.3
-
26
-
-
0019172988
-
Willardiine: A potent quisqualate-like excitant
-
Evans, R.H., Jones, A.W. and Watkins, J.C. (1980) ‘Willardiine: a potent quisqualate-like excitant’, J. Physiol. (London) 308: 71P-72P.
-
(1980)
J. Physiol. (London)
, vol.308
, pp. 71P-72P
-
-
Evans, R.H.1
Jones, A.W.2
Watkins, J.C.3
-
27
-
-
0032474872
-
Heteroaryl analogues of AMPA. 2. Synthesis, absolute stereochemistry, photochemistry, and structure-activity relationships
-
Falch, E., Brehm, L., Mikkelsen, I., Johansen, T.N., Skjærbæk, N., Nielsen, B., Stensbøl, T.B., Ebert, B. and Krogsgaard-Larsen, P. (1998) ‘Heteroaryl analogues of AMPA. 2. Synthesis, absolute stereochemistry, photochemistry, and structure-activity relationships’, J. Med. Chem. 41: 2513-2523.
-
(1998)
J. Med. Chem
, vol.41
, pp. 2513-2523
-
-
Falch, E.1
Brehm, L.2
Mikkelsen, I.3
Johansen, T.N.4
Skjærbæk, N.5
Nielsen, B.6
Stensbøl, T.B.7
Ebert, B.8
Krogsgaard-Larsen, P.9
-
28
-
-
0028983334
-
3H]Aniracetam binds to specific recognition sites in brain membranes
-
3H]Aniracetam binds to specific recognition sites in brain membranes’, J. Neurochem. 65: 912-918.
-
(1995)
J. Neurochem
, vol.65
, pp. 912-918
-
-
Fallarino, F.1
Genazzani, A.A.2
Silla, S.3
Lepiscopo, M.R.4
Camici, O.5
Corazzi, L.6
Nicoletti, F.7
Fioretti, M.C.8
-
29
-
-
0029990678
-
New developments in the molecular pharmacology of α-amino-3-hydroxy-5-methyl-4-isoxazole propionate and kainate receptors
-
Fletcher, E.J. and Lodge, D. (1996) ‘New developments in the molecular pharmacology of α-amino-3-hydroxy-5-methyl-4-isoxazole propionate and kainate receptors’, Pharmacol. Ther. 70: 65-89.
-
(1996)
Pharmacol. Ther
, vol.70
, pp. 65-89
-
-
Fletcher, E.J.1
Lodge, D.2
-
30
-
-
0023805670
-
Quinoxalinediones selectively block quisqualate and kainate receptors and synaptic events in rat neocortex and hippocampus and frog spinal cord in vitro
-
Fletcher, E.J., Martin, D., Aram, J.A., Lodge, D. and Honoré, T. (1988) ‘Quinoxalinediones selectively block quisqualate and kainate receptors and synaptic events in rat neocortex and hippocampus and frog spinal cord in vitro’, Br. J. Pharmacol. 95: 585-597.
-
(1988)
Br. J. Pharmacol
, vol.95
, pp. 585-597
-
-
Fletcher, E.J.1
Martin, D.2
Aram, J.A.3
Lodge, D.4
Honoré, T.5
-
31
-
-
0021434352
-
Acidic amino acid binding sites in mammalian neuronal membranes: Their characteristics and relationship to synaptic receptors
-
Foster, A.C. and Fagg, G.E. (1984) ‘Acidic amino acid binding sites in mammalian neuronal membranes: their characteristics and relationship to synaptic receptors’, Brain Res. Rev. 7: 103-164.
-
(1984)
Brain Res. Rev
, vol.7
, pp. 103-164
-
-
Foster, A.C.1
Fagg, G.E.2
-
32
-
-
0029045977
-
Synthesis, resolution, and biological evaluation of the four stereoisomers of 4-methylglutamic acid: Selective probes of kainate receptors
-
Gu, Z.-Q., Hesson, D.P., Pelletier, J.C., Maccecchini, M.-L., Zhou, L.M. and Skolnick, P. (1995) ‘Synthesis, resolution, and biological evaluation of the four stereoisomers of 4-methylglutamic acid: selective probes of kainate receptors’, J. Med. Chem. 38: 2518-2520.
-
(1995)
J. Med. Chem
, vol.38
, pp. 2518-2520
-
-
Gu, Z.-Q.1
Hesson, D.P.2
Pelletier, J.C.3
Maccecchini, M.-L.4
Zhou, L.M.5
Skolnick, P.6
-
33
-
-
0019262610
-
Isoxazole amino acids as glutamic acid agonists. Synthesis of some analogues and homologues of ibotenic acid
-
Hansen, J.J. and Krogsgaard-Larsen, P. (1980) ‘Isoxazole amino acids as glutamic acid agonists. Synthesis of some analogues and homologues of ibotenic acid’, J. Chem. Soc. Perkin Trans. I: 1826-1833.
-
(1980)
J. Chem. Soc. Perkin Trans
, vol.1
, pp. 1826-1833
-
-
Hansen, J.J.1
Krogsgaard-Larsen, P.2
-
34
-
-
0020549223
-
Enzymic resolution and binding to rat brain membranes of the glutamic acid agonist α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid
-
Hansen, J.J., Lauridsen, J., Nielsen, E. and Krogsgaard-Larsen, P. (1983) ‘Enzymic resolution and binding to rat brain membranes of the glutamic acid agonist α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid’, J. Med. Chem. 26: 901-903.
-
(1983)
J. Med. Chem
, vol.26
, pp. 901-903
-
-
Hansen, J.J.1
Lauridsen, J.2
Nielsen, E.3
Krogsgaard-Larsen, P.4
-
35
-
-
0024435507
-
Excitatory amino acid agonists. Enzymic resolution, X-ray structure and enantioselective activities of (R)- and (S)-bromohomoibotenic acid
-
Hansen, J.J., Nielsen, B., Krogsgaard-Larsen, P., Brehm, L., Nielsen, E.Ø. and Curtis, D.R. (1989) ‘Excitatory amino acid agonists. Enzymic resolution, X-ray structure and enantioselective activities of (R)- and (S)-bromohomoibotenic acid’, J. Med. Chem. 32: 2254-2260.
-
(1989)
J. Med. Chem
, vol.32
, pp. 2254-2260
-
-
Hansen, J.J.1
Nielsen, B.2
Krogsgaard-Larsen, P.3
Brehm, L.4
Nielsen, E.Ø.5
Curtis, D.R.6
-
36
-
-
0000064234
-
AMPA receptor agonists: Structural, conformational and stereochemical aspects
-
P. Krogsgaard-Larsen and J.J. Hansen (eds), Chichester: Ellis Horwood
-
Hansen, J.J., Jørgensen, F.S., Lund, T.M., Nielsen, B., Reinhardt, A., Breum, I., Brehm, L. and Krogsgaard-Larsen, P. (1992) ‘AMPA receptor agonists: structural, conformational and stereochemical aspects’, in P. Krogsgaard-Larsen and J.J. Hansen (eds) Excitatory Amino Acid Receptors: Design of Agonists and Antagonists, Chichester: Ellis Horwood, pp. 216-245.
-
(1992)
Excitatory Amino Acid Receptors: Design of Agonists and Antagonists
, pp. 216-245
-
-
Hansen, J.J.1
Jørgensen, F.S.2
Lund, T.M.3
Nielsen, B.4
Reinhardt, A.5
Breum, I.6
Brehm, L.7
Krogsgaard-Larsen, P.8
-
38
-
-
0021991131
-
Complex structure of quisqualate-sensitive glutamate receptors in rat cortex
-
Honoré, T. and Nielsen, M. (1985) ‘Complex structure of quisqualate-sensitive glutamate receptors in rat cortex’, Neurosci. Lett. 54: 27-32.
-
(1985)
Neurosci. Lett
, vol.54
, pp. 27-32
-
-
Honoré, T.1
Nielsen, M.2
-
39
-
-
0023767546
-
Quinoxalinediones: Potent competitive non-NMDA glutamate receptor antagonists
-
Honoré, T., Davies, S.N., Drejer, J., Fletcher, E.J., Jacobsen, P., Lodge, D. and Nielsen, F.E. (1988) ‘Quinoxalinediones: potent competitive non-NMDA glutamate receptor antagonists’, Science 241: 701-703.
-
(1988)
Science
, vol.241
, pp. 701-703
-
-
Honoré, T.1
Davies, S.N.2
Drejer, J.3
Fletcher, E.J.4
Jacobsen, P.5
Lodge, D.6
Nielsen, F.E.7
-
40
-
-
0025040913
-
Glutamate receptor channels in rat DRG neurons: Activation by kainate and quisqualate and blockade of desensitization by Con A
-
Huettner, J.E. (1990) ‘Glutamate receptor channels in rat DRG neurons: activation by kainate and quisqualate and blockade of desensitization by Con A’, Neuron 5: 255-266.
-
(1990)
Neuron
, vol.5
, pp. 255-266
-
-
Huettner, J.E.1
-
41
-
-
0025786139
-
Aniracetam reduces glutamate receptor desensitization and slows the decay of fast excitatory synaptic currents in the hippocampus
-
Isaacson, J.S. and Nicoll, R.A. (1991) ‘Aniracetam reduces glutamate receptor desensitization and slows the decay of fast excitatory synaptic currents in the hippocampus’, Proc. Natl. Acad. Sci. USA 88: 10,936-10,940.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 10,936-10,940
-
-
Isaacson, J.S.1
Nicoll, R.A.2
-
42
-
-
0023775468
-
Acromelic acid is a much more potent excitant than kainic acid or domoic acid in the isolated rat spinal cord
-
Ishida, M. and Shinozaki, H. (1988) ‘Acromelic acid is a much more potent excitant than kainic acid or domoic acid in the isolated rat spinal cord’, Brain Res. 474: 386-389.
-
(1988)
Brain Res
, vol.474
, pp. 386-389
-
-
Ishida, M.1
Shinozaki, H.2
-
43
-
-
0025726155
-
A novel glutamate agonist, TAN-950 A, isolated from streptomycetes
-
Iwama, T., Nagai, Y., Tamura, N., Harada, S. and Nagaoka, A. (1991) ‘A novel glutamate agonist, TAN-950 A, isolated from streptomycetes’, Eur. J. Pharmacol. 197: 187-192.
-
(1991)
Eur. J. Pharmacol
, vol.197
, pp. 187-192
-
-
Iwama, T.1
Nagai, Y.2
Tamura, N.3
Harada, S.4
Nagaoka, A.5
-
44
-
-
0030693165
-
Synthesis of willardiine and 6-azawillardiine analogs: Pharmacological characterization on cloned homomeric human AMPA and kainate receptor subtypes
-
Jane, D.E., Hoo, K., Kamboj, R., Deverill, M., Bleakman, D. and Mandelzys, A. (1997) ‘Synthesis of willardiine and 6-azawillardiine analogs: pharmacological characterization on cloned homomeric human AMPA and kainate receptor subtypes’, J. Med. Chem. 40: 3645-3650.
-
(1997)
J. Med. Chem
, vol.40
, pp. 3645-3650
-
-
Jane, D.E.1
Hoo, K.2
Kamboj, R.3
Deverill, M.4
Bleakman, D.5
Mandelzys, A.6
-
46
-
-
0030915716
-
‘AMPA receptor agonists: Resolution, configurational assignment, and pharmacology or (+)-(S)- and (-)-(R)-2-amino-3-[3-hydroxy-5-(2-pyridyl)-isoxazol-4]-propionic acid (2-Py-AMPA)'
-
Johansen, T.N, Ebert, B., Falch, E. and Krogsgaard-Larsen, P. (1997a) ‘AMPA receptor agonists: resolution, configurational assignment, and pharmacology or (+)-(S)- and (-)-(R)-2-amino-3-[3-hydroxy-5-(2-pyridyl)-isoxazol-4]-propionic acid (2-Py-AMPA)', Chirality 9: 274-280.
-
(1997)
Chirality
, vol.9
, pp. 274-280
-
-
Johansen, T.N.1
Ebert, B.2
Falch, E.3
Krogsgaard-Larsen, P.4
-
47
-
-
0030955204
-
‘Excitatory amino acid receptor antagonists: Resolution, absolute stereochemistry, and pharmacology of (S)- and (R)-2-amino-2-(5-tert-butyl-3-hydroxyisoxazol-4-yl)acetic acid (ATAA)'
-
Johansen, T.N., Frydenvang, K., Ebert, B., Madsen, U. and Krogsgaard-Larsen, P. (1997b) ‘Excitatory amino acid receptor antagonists: resolution, absolute stereochemistry, and pharmacology of (S)- and (R)-2-amino-2-(5-tert-butyl-3-hydroxyisoxazol-4-yl)acetic acid (ATAA)', Chirality 9: 529-536.
-
(1997)
Chirality
, vol.9
, pp. 529-536
-
-
Johansen, T.N.1
Frydenvang, K.2
Ebert, B.3
Madsen, U.4
Krogsgaard-Larsen, P.5
-
48
-
-
0032510387
-
Excitatory amino acid receptor ligands: Resolution, absolute stereochemistry, and enantiopharmacology of 2-amino-3-(4-butyl-3-hydroxyisoxazolyl-5-yl)propionic acid
-
Johansen, T.N., Ebert, B., Bräuner-Osborne, H., Didriksen, M., Christensen, I.T., Søby, K.K., Madsen, U., Krogsgaard-Larsen, P. and Brehm, L. (1998) ‘Excitatory amino acid receptor ligands: resolution, absolute stereochemistry, and enantiopharmacology of 2-amino-3-(4-butyl-3-hydroxyisoxazolyl-5-yl)propionic acid’, J. Med. Chem. 41: 930-939.
-
(1998)
J. Med. Chem
, vol.41
, pp. 930-939
-
-
Johansen, T.N.1
Ebert, B.2
Bräuner-Osborne, H.3
Didriksen, M.4
Christensen, I.T.5
Søby, K.K.6
Madsen, U.7
Krogsgaard-Larsen, P.8
Brehm, L.9
-
49
-
-
0034778767
-
Resolution, configurational assignment and enantiopharmacology at glutamate receptors of 2-amino-3-(3-carboxy-5-methyl-4-isoxazolyl)propionic acid (ACPA) and Demethyl-ACPA
-
(in press)
-
Johansen, T.N., Stensbøl, T., Neilsen, B., Vogensen, S.B., Frydenvang, K., Sløk, F., Bräuner-Osborne, H., Madsen, U. and Krogsgaard-Larsen (2001) ‘Resolution, configurational assignment and enantiopharmacology at glutamate receptors of 2-amino-3-(3-carboxy-5-methyl-4-isoxazolyl)propionic acid (ACPA) and Demethyl-ACPA’, Chirality (in press).
-
(2001)
Chirality
-
-
Johansen, T.N.1
Stensbøl, T.2
Neilsen, B.3
Vogensen, S.B.4
Frydenvang, K.5
Sløk, F.6
Bräuner-Osborne, H.7
Madsen, U.8
Krogsgaard-Larsen9
-
50
-
-
0030836752
-
Desensitization of kainate receptors by kainate, glutamate and diastereomers of 4-methylglutamate
-
Jones, K.A., Wilding, T.J., Huettner, J.E. and Costa, A.-M. (1997) ‘Desensitization of kainate receptors by kainate, glutamate and diastereomers of 4-methylglutamate’, Neuropharmacology 36: 853-863.
-
(1997)
Neuropharmacology
, vol.36
, pp. 853-863
-
-
Jones, K.A.1
Wilding, T.J.2
Huettner, J.E.3
Costa, A.-M.4
-
51
-
-
0019223440
-
New class of glutamate agonist structurally related to ibotenic acid
-
Krogsgaard-Larsen, P., Honoré, T., Hansen, J.J., Curtis, D.R. and Lodge, D. (1980) ‘New class of glutamate agonist structurally related to ibotenic acid’, Nature 284: 64-66.
-
(1980)
Nature
, vol.284
, pp. 64-66
-
-
Krogsgaard-Larsen, P.1
Honoré, T.2
Hansen, J.J.3
Curtis, D.R.4
Lodge, D.5
-
52
-
-
0021953106
-
Synthesis and structure-activity studies on excitatory amino acids structurally related to ibotenic acid
-
Krogsgaard-Larsen, P., Brehm, L., Johansen, J.S., Vinzents, P., Lauridsen, J. and Curtis, D.R. (1985) ‘Synthesis and structure-activity studies on excitatory amino acids structurally related to ibotenic acid’, J. Med. Chem. 28: 673-679.
-
(1985)
J. Med. Chem
, vol.28
, pp. 673-679
-
-
Krogsgaard-Larsen, P.1
Brehm, L.2
Johansen, J.S.3
Vinzents, P.4
Lauridsen, J.5
Curtis, D.R.6
-
53
-
-
0025970909
-
‘Novel class of amino acid antagonists at non-N-methyl-D-aspartic acid excitatory amino acid receptors. Synthesis
-
vitro and in vivo pharmacology, and neuroprotection’
-
Krogsgaard-Larsen, P., Ferkany, J.W., Nielsen, E.Ø., Madsen, U., Ebert, B., Johansen, J.S., Diemer, N.H., Bruhn, T., Beattie, D.T. and Curtis, D.R. (1991) ‘Novel class of amino acid antagonists at non-N-methyl-D-aspartic acid excitatory amino acid receptors. Synthesis, in vitro and in vivo pharmacology, and neuroprotection’, J. Med. Chem. 34: 123-130.
-
(1991)
J. Med. Chem
, vol.34
, pp. 123-130
-
-
Krogsgaard-Larsen, P.1
Ferkany, J.W.2
Nielsen, E.Ø.3
Madsen, U.4
Ebert, B.5
Johansen, J.S.6
Diemer, N.H.7
Bruhn, T.8
Beattie, D.T.9
Curtis, D.R.10
-
54
-
-
0021910630
-
Ibotenic acid analogues. Synthesis, molecular flexibility, and in vitro activity of agonists and antagonists at central glutamic acid receptors
-
Lauridsen, J., Honoré, T. and Krogsgaard-Larsen, P. (1985) ‘Ibotenic acid analogues. Synthesis, molecular flexibility, and in vitro activity of agonists and antagonists at central glutamic acid receptors’, J. Med. Chem. 28: 668-672.
-
(1985)
J. Med. Chem
, vol.28
, pp. 668-672
-
-
Lauridsen, J.1
Honoré, T.2
Krogsgaard-Larsen, P.3
-
55
-
-
0022671193
-
Ibotenic acid analogues. Synthesis and biological testing of two bicyclic 3-isoxazolol amino acids
-
Madsen, U., Schaumburg, K., Brehm, L., Curtis, D.R. and Krogsgaard-Larsen, P. (1986) ‘Ibotenic acid analogues. Synthesis and biological testing of two bicyclic 3-isoxazolol amino acids’, Acta Chem. Scand. B40: 92-97.
-
(1986)
Acta Chem. Scand
, vol.B40
, pp. 92-97
-
-
Madsen, U.1
Schaumburg, K.2
Brehm, L.3
Curtis, D.R.4
Krogsgaard-Larsen, P.5
-
56
-
-
0025021573
-
Relationship between structure, conformational flexibility, and biological activity of agonists and antagonists at the N-methyl-D-aspartic acid subtype of excitatory amino acid receptors
-
Madsen, U., Brehm, L., Schaumburg, K., Jørgensen, F.S. and Krogsgaard-Larsen, P. (1990) ‘Relationship between structure, conformational flexibility, and biological activity of agonists and antagonists at the N-methyl-D-aspartic acid subtype of excitatory amino acid receptors’, J. Med. Chem. 33: 374-380.
-
(1990)
J. Med. Chem
, vol.33
, pp. 374-380
-
-
Madsen, U.1
Brehm, L.2
Schaumburg, K.3
Jørgensen, F.S.4
Krogsgaard-Larsen, P.5
-
57
-
-
0026803105
-
Synthesis and pharmacology of (RS)-2-amino-3-(3-hydroxy-5-flouromethyl-4-isoxazolyl)propionic acid, a potent AMPA receptor agonist
-
Madsen, U., Ebert, B., Krogsgaard-Larsen, P. and Wong, E.H.F. (1992) ‘Synthesis and pharmacology of (RS)-2-amino-3-(3-hydroxy-5-flouromethyl-4-isoxazolyl)propionic acid, a potent AMPA receptor agonist’, Eur. J. Med. Chem. 27: 479-484.
-
(1992)
Eur. J. Med. Chem
, vol.27
, pp. 479-484
-
-
Madsen, U.1
Ebert, B.2
Krogsgaard-Larsen, P.3
Wong, E.H.F.4
-
58
-
-
0026569392
-
Heterocyclic excitatory amino acids. Synthesis and biological activity of novel analogues of AMPA
-
Madsen, U. and Wong, E.H.F. (1992) ‘Heterocyclic excitatory amino acids. Synthesis and biological activity of novel analogues of AMPA’, J. Med. Chem. 35: 107-111.
-
(1992)
J. Med. Chem
, vol.35
, pp. 107-111
-
-
Madsen, U.1
Wong, E.H.F.2
-
59
-
-
0027463640
-
The non-depolarizing D-form of bromohomoibotenic acid enhances depolarizations evoked by the L-form or quisqualate
-
Madsen, U., Ebert, B., Hansen, J.J. and Krogsgaard-Larsen, P. (1993a) ‘The non-depolarizing D-form of bromohomoibotenic acid enhances depolarizations evoked by the L-form or quisqualate’, Eur. J. Pharmacol. 230: 383-386.
-
(1993)
Eur. J. Pharmacol
, vol.230
, pp. 383-386
-
-
Madsen, U.1
Ebert, B.2
Hansen, J.J.3
Krogsgaard-Larsen, P.4
-
60
-
-
0027433244
-
Design, synthesis and pharmacology of model compounds for indirect elucidation of the topography of AMPA receptor sites
-
Madsen, U., Frølund, B., Lund, T.M., Ebert, B. and Krogsgaard-Larsen, P. (1993b) ‘Design, synthesis and pharmacology of model compounds for indirect elucidation of the topography of AMPA receptor sites’, Eur. J. Med. Chem. 28: 791-800.
-
(1993)
Eur. J. Med. Chem
, vol.28
, pp. 791-800
-
-
Madsen, U.1
Frølund, B.2
Lund, T.M.3
Ebert, B.4
Krogsgaard-Larsen, P.5
-
61
-
-
0029863920
-
Synthesis and pharmacology of highly selective carboxy and phosphono isoxazole amino acid AMPA receptor antagonists
-
Madsen, U., Bang-Andersen, B., Brehm, L., Christensen, I.T., Ebert, B., Kristoffersen, I.T.S., Lang, Y. and Krogsgaard-Larsen, P. (1996) ‘Synthesis and pharmacology of highly selective carboxy and phosphono isoxazole amino acid AMPA receptor antagonists’, J. Med. Chem. 39: 1682-1691.
-
(1996)
J. Med. Chem
, vol.39
, pp. 1682-1691
-
-
Madsen, U.1
Bang-Andersen, B.2
Brehm, L.3
Christensen, I.T.4
Ebert, B.5
Kristoffersen, I.T.S.6
Lang, Y.7
Krogsgaard-Larsen, P.8
-
62
-
-
0034092795
-
Ionotropic excitatory amino acid receptor ligands. Synthesis and pharmacology of a new amino acid AMPA antagonist
-
Madsen, U., Sløk, F.A., Stensbøl, T.B., Bräuner-Osborne, H., Lützhøft, H.-C.H., Poulsen, M., Eriksen, L. and Krogsgaard-Larsen, P. (2000) ‘Ionotropic excitatory amino acid receptor ligands. Synthesis and pharmacology of a new amino acid AMPA antagonist’, Eur. J. Med. Chem. 35: 69-76.
-
(2000)
Eur. J. Med. Chem
, vol.35
, pp. 69-76
-
-
Madsen, U.1
Sløk, F.A.2
Stensbøl, T.B.3
Bräuner-Osborne, H.4
Lützhøft, H.-C.H.5
Poulsen, M.6
Eriksen, L.7
Krogsgaard-Larsen, P.8
-
63
-
-
0018392022
-
The antagonism of amino acid-induced excitation of spinal neurons in the cat
-
McLennan, H. and Lodge, D. (1979) ‘The antagonism of amino acid-induced excitation of spinal neurons in the cat’, Brain Res. 169: 83-90.
-
(1979)
Brain Res
, vol.169
, pp. 83-90
-
-
McLennan, H.1
Lodge, D.2
-
64
-
-
0024596865
-
The excitatory amino acid receptors: Their classes, pharmacology, and distinct properties in the function of the central nervous system
-
Monaghan, D.T., Bridges, R.J. and Cotman, C.W. (1989) ‘The excitatory amino acid receptors: their classes, pharmacology, and distinct properties in the function of the central nervous system’, Ann. Rev. Pharmacol. Toxicol. 29: 365-402.
-
(1989)
Ann. Rev. Pharmacol. Toxicol
, vol.29
, pp. 365-402
-
-
Monaghan, D.T.1
Bridges, R.J.2
Cotman, C.W.3
-
65
-
-
0032731808
-
Resolution, absolute stereochemistry, and enantiopharmacology of the GluR1-4 and GluR5 antagonist 2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acid
-
Møller, E.H., Egebjerg, J., Brehm, L., Stensbøl, T.B., Johansen, T.N., Madsen, U. and Krogsgaard-Larsen, P. (1999) ‘Resolution, absolute stereochemistry, and enantiopharmacology of the GluR1-4 and GluR5 antagonist 2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acid’, Chirality 11: 752-759.
-
(1999)
Chirality
, vol.11
, pp. 752-759
-
-
Møller, E.H.1
Egebjerg, J.2
Brehm, L.3
Stensbøl, T.B.4
Johansen, T.N.5
Madsen, U.6
Krogsgaard-Larsen, P.7
-
66
-
-
0027455114
-
Enzymatic resolution of AMPA by use of a-chymotrypsin
-
Nielsen, B., Fisker, H., Ebert, B., Madsen, U., Curtis, D.R., Krogsgaard-Larsen, P. and Hansen, J.J. (1993) ‘Enzymatic resolution of AMPA by use of a-chymotrypsin’, Bioorg. Med. Chem. Lett. 3: 107-114.
-
(1993)
Bioorg. Med. Chem. Lett
, vol.3
, pp. 107-114
-
-
Nielsen, B.1
Fisker, H.2
Ebert, B.3
Madsen, U.4
Curtis, D.R.5
Krogsgaard-Larsen, P.6
Hansen, J.J.7
-
67
-
-
0028314957
-
'6-(1H-Imidazol-1-yl)-7-nitro-2,3-(1H,4H)-quinoxalinedione hydrochloride (YM90K) and related compounds: Structure-activity relationships for the AMPA-type non-NMDA receptor’
-
Ohmori, J., Sakamoto, S., Kubota, H., Shimizu-Sasamata, M., Okada, M., Kawasaki, S., Hidaka, K., Togami, J., Furuya, T. and Murase, K. (1994) '6-(1H-Imidazol-1-yl)-7-nitro-2,3-(1H,4H)-quinoxalinedione hydrochloride (YM90K) and related compounds: structure-activity relationships for the AMPA-type non-NMDA receptor’, J. Med. Chem. 37: 467-475.
-
(1994)
J. Med. Chem
, vol.37
, pp. 467-475
-
-
Ohmori, J.1
Sakamoto, S.2
Kubota, H.3
Shimizu-Sasamata, M.4
Okada, M.5
Kawasaki, S.6
Hidaka, K.7
Togami, J.8
Furuya, T.9
Murase, K.10
-
68
-
-
0032191984
-
Decahydroisoquinolines: Novel competitive AMPA/kainate antagonists with neuroprotective effects in global cerebral ischaemia
-
O’Neill, M.J., Bond, A., Ornstein, P.L., Ward, M.A., Hicks, C.A., Hoo, K., Bleakman, D. and Lodge, D. (1998) ‘Decahydroisoquinolines: novel competitive AMPA/kainate antagonists with neuroprotective effects in global cerebral ischaemia’, Neuropharmacology 37: 1211-1222.
-
(1998)
Neuropharmacology
, vol.37
, pp. 1211-1222
-
-
O’Neill, M.J.1
Bond, A.2
Ornstein, P.L.3
Ward, M.A.4
Hicks, C.A.5
Hoo, K.6
Bleakman, D.7
Lodge, D.8
-
69
-
-
0027296719
-
'(3SR,4aRS,6RS,8aRS)-6-[2-(1H-Tetrazol-5-yl)ethyl)decahydroisoquinoline-3-carboxylic acid: A structurally novel, systematically active, competitive AMPA receptor antagonist’
-
Ornstein, P.L., Arnold, M.B., Augenstein, N.K., Lodge, D., Leander, D.J. and Schoepp, D.D. (1993) '(3SR,4aRS,6RS,8aRS)-6-[2-(1H-Tetrazol-5-yl)ethyl)decahydroisoquinoline-3-carboxylic acid: a structurally novel, systematically active, competitive AMPA receptor antagonist’, J. Med. Chem. 36: 2046-2048.
-
(1993)
J. Med. Chem
, vol.36
, pp. 2046-2048
-
-
Ornstein, P.L.1
Arnold, M.B.2
Augenstein, N.K.3
Lodge, D.4
Leander, D.J.5
Schoepp, D.D.6
-
70
-
-
0028836733
-
Selective antagonism of AMPA receptors unmasks kainate receptor-mediated responses in hippocampal neurons
-
Paternain, A.V., Morales, M. and Lerma, J. (1995) ‘Selective antagonism of AMPA receptors unmasks kainate receptor-mediated responses in hippocampal neurons’, Neuron 14: 185-189.
-
(1995)
Neuron
, vol.14
, pp. 185-189
-
-
Paternain, A.V.1
Morales, M.2
Lerma, J.3
-
71
-
-
0025456905
-
Structure-activity relationships for amino acid transmitter candidates acting at N-methyl-D-aspartate and quisqualate receptors
-
Patneau, D.K. and Mayer, M.L. (1990) ‘Structure-activity relationships for amino acid transmitter candidates acting at N-methyl-D-aspartate and quisqualate receptors’, J. Neurosci. 10: 2385-2399.
-
(1990)
J. Neurosci
, vol.10
, pp. 2385-2399
-
-
Patneau, D.K.1
Mayer, M.L.2
-
72
-
-
0026556811
-
Activation and desensitization of AMPA/kainate receptors by novel derivatives of willardiine
-
Patneau, D.K., Mayer, M.L., Jane, D.E. and Watkins, J.C. (1992) ‘Activation and desensitization of AMPA/kainate receptors by novel derivatives of willardiine’, J. Neurosci. 12: 595-606.
-
(1992)
J. Neurosci
, vol.12
, pp. 595-606
-
-
Patneau, D.K.1
Mayer, M.L.2
Jane, D.E.3
Watkins, J.C.4
-
73
-
-
0027228511
-
Hippocampal neurons exhibit cyclothiazidesensitive rapidly desensitizing responses to kainate
-
Patneau, D.K., Vyklicky, L.J. and Mayer, M.L. (1993) ‘Hippocampal neurons exhibit cyclothiazidesensitive rapidly desensitizing responses to kainate’, J. Neurosci. 13: 595-606.
-
(1993)
J. Neurosci
, vol.13
, pp. 595-606
-
-
Patneau, D.K.1
Vyklicky, L.J.2
Mayer, M.L.3
-
74
-
-
0025117827
-
'2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline. A neuroprotectant for cerebral ischemia’
-
Sheardown, M.J., Nielsen, E.Ø., Hansen, A.J., Jacobsen, P. and Honoré, T. (1990) '2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline. A neuroprotectant for cerebral ischemia’, Science 247: 571-574.
-
(1990)
Science
, vol.247
, pp. 571-574
-
-
Sheardown, M.J.1
Nielsen, E.Ø.2
Hansen, A.J.3
Jacobsen, P.4
Honoré, T.5
-
75
-
-
0023877576
-
Pharmacology of the glutamate receptor
-
Shinozaki, H. (1988) ‘Pharmacology of the glutamate receptor’, Prog. Neurobiol. 30: 399-435.
-
(1988)
Prog. Neurobiol
, vol.30
, pp. 399-435
-
-
Shinozaki, H.1
-
76
-
-
0001828255
-
Kainic acid receptor agonists
-
P. Krogsgaard-Larsen and J.J. Hansen (eds), Chichester: Ellis Horwood
-
Shinozaki, H. (1992) ‘Kainic acid receptor agonists’, in P. Krogsgaard-Larsen and J.J. Hansen (eds) Excitatory Amino Acid Receptors: Design of Agonists and Antagonists, Chichester: Ellis Horwood, pp. 261-291.
-
(1992)
Excitatory Amino Acid Receptors: Design of Agonists and Antagonists
, pp. 261-291
-
-
Shinozaki, H.1
-
77
-
-
37049082189
-
Excitatory amino acids. Synthesis of (RS)-2-amino-3-(5-cyclopropyl-3-hydroxyisoxazol-4-yl)propionic acid, a new potent and specific AMPA receptor agonist
-
Skjærbæk, N., Ebert, B., Falch, E., Brehm, L. and Krogsgaard-Larsen, P. (1995) ‘Excitatory amino acids. Synthesis of (RS)-2-amino-3-(5-cyclopropyl-3-hydroxyisoxazol-4-yl)propionic acid, a new potent and specific AMPA receptor agonist’, J. Chem. Soc. Perkin Trans. I: 221-225.
-
(1995)
J. Chem. Soc. Perkin Trans
, vol.1
, pp. 221-225
-
-
Skjærbæk, N.1
Ebert, B.2
Falch, E.3
Brehm, L.4
Krogsgaard-Larsen, P.5
-
78
-
-
0022370635
-
Glutamate stimulates inositol phosphate formation in striatal neurons
-
Sladeczek, F., Pin, J.P., Récasens, M., Bockaert, J. and Wiess, S. (1985) ‘Glutamate stimulates inositol phosphate formation in striatal neurons’, Nature 317: 717-719.
-
(1985)
Nature
, vol.317
, pp. 717-719
-
-
Sladeczek, F.1
Pin, J.P.2
Récasens, M.3
Bockaert, J.4
Wiess, S.5
-
79
-
-
0030995529
-
‘Excitatory amino acid receptor agonists. Synthesis and pharmacology of analogues of 2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic acid (AMPA)'
-
Sløk, F.A., Ebert, B., Lang, Y., Krogsgaard-Larsen, P., Lenz, S.M. and Madsen, U. (1997) ‘Excitatory amino acid receptor agonists. Synthesis and pharmacology of analogues of 2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic acid (AMPA)', Eur. J. Med. Chem. 32: 329-338.
-
(1997)
Eur. J. Med. Chem
, vol.32
, pp. 329-338
-
-
Sløk, F.A.1
Ebert, B.2
Lang, Y.3
Krogsgaard-Larsen, P.4
Lenz, S.M.5
Madsen, U.6
-
80
-
-
0032872268
-
Resolution, absolute stereochemistry and molecular pharmacology of the enantiomers of ATPA
-
Stensbøl, T.B., Borre, L., Johansen, T.N., Egebjerg, J., Madsen, U., Ebert, B. and Krogsgaard-Larsen, P. (1999a) ‘Resolution, absolute stereochemistry and molecular pharmacology of the enantiomers of ATPA’, Eur. J. Pharmacol. 380: 153-162.
-
(1999)
Eur. J. Pharmacol
, vol.380
, pp. 153-162
-
-
Stensbøl, T.B.1
Borre, L.2
Johansen, T.N.3
Egebjerg, J.4
Madsen, U.5
Ebert, B.6
Krogsgaard-Larsen, P.7
-
81
-
-
0033021196
-
3H]2-amino-3-(3-carboxy-5-methyl-4-isoxazolyl)propionic acid
-
3H]2-amino-3-(3-carboxy-5-methyl-4-isoxazolyl)propionic acid’, Eur. J. Pharmacol. 373: 251-262.
-
(1999)
Eur. J. Pharmacol
, vol.373
, pp. 251-262
-
-
Stensbøl, T.B.1
Sløk, F.A.2
Trometer, J.3
Hurt, J.4
Ebert, B.5
Kjøller, C.6
Egebjerg, J.7
Madsen, U.8
Diemer, N.H.9
Krogsgaard-Larsen, P.10
-
82
-
-
0031750767
-
Kainate receptors exhibit differential sensitivities to (S)-5-iodowillardiine
-
Swanson, G.T., Green, T. and Heinemann, S.F. (1998) ‘Kainate receptors exhibit differential sensitivities to (S)-5-iodowillardiine’, Mol. Pharmacol. 53: 942-949.
-
(1998)
Mol. Pharmacol
, vol.53
, pp. 942-949
-
-
Swanson, G.T.1
Green, T.2
Heinemann, S.F.3
-
83
-
-
0024317594
-
‘Electrophysiological studies with a 2,3-benzodiazepine muscle relaxant: GYKI52466'
-
Tarnawa, I., Farkas, S., Berzsenyi, P., Pataki, A. and Andrási, F. (1989) ‘Electrophysiological studies with a 2,3-benzodiazepine muscle relaxant: GYKI52466', Eur. J. Pharmacol. 167: 193-199.
-
(1989)
Eur. J. Pharmacol
, vol.167
, pp. 193-199
-
-
Tarnawa, I.1
Farkas, S.2
Berzsenyi, P.3
Pataki, A.4
Andrási, F.5
-
84
-
-
0026563864
-
Relief of experimental spasticity and anxiolytic/anticonvulsant actions of the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate antagonist 2,3-dihydroxy-6-nitro-7-sulfamoylbenzo(F)quinoxaline
-
Turski, L., Jacobsen, P., Honoré, T. and Stephens, D.N. (1992) ‘Relief of experimental spasticity and anxiolytic/anticonvulsant actions of the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate antagonist 2,3-dihydroxy-6-nitro-7-sulfamoylbenzo(F)quinoxaline’, J. Pharmacol. Exp. Ther. 260: 742-747.
-
(1992)
J. Pharmacol. Exp. Ther
, vol.260
, pp. 742-747
-
-
Turski, L.1
Jacobsen, P.2
Honoré, T.3
Stephens, D.N.4
-
85
-
-
13144306063
-
ZK200775: A phosphonate quinoxazolinedione AMPA antagonist for neuroprotection in stroke and trauma
-
Turski, L., Huth, A., Sheardown, M., McDonald, F., Neuhaus, R., Schneider, H.H., Dirnagl, U., Wiegand, F., Jacobsen, P. and Ottow, E. (1998) ‘ZK200775: A phosphonate quinoxazolinedione AMPA antagonist for neuroprotection in stroke and trauma’, Proc. Natl. Acad. Sci. USA 95: 10,960-10,965.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 10,960-10,965
-
-
Turski, L.1
Huth, A.2
Sheardown, M.3
McDonald, F.4
Neuhaus, R.5
Schneider, H.H.6
Dirnagl, U.7
Wiegand, F.8
Jacobsen, P.9
Ottow, E.10
-
86
-
-
0028169790
-
Selective block of recombinant GluR6 receptors by NS-102, a novel non-NMDA receptor antagonist
-
Verdoorn, T.A., Johansen, T.H., Drejer, J. and Nielsen, E.Ø. (1994) ‘Selective block of recombinant GluR6 receptors by NS-102, a novel non-NMDA receptor antagonist’, Eur. J. Pharmacol. 269: 43-49.
-
(1994)
Eur. J. Pharmacol
, vol.269
, pp. 43-49
-
-
Verdoorn, T.A.1
Johansen, T.H.2
Drejer, J.3
Nielsen, E.Ø.4
-
87
-
-
0026457736
-
Stereoselective effects of AMOA on non-NMDA receptors expressed in Xenopus oocytes
-
Wahl, P., Nielsen, B., Krogsgaard-Larsen, P., Hansen, J.J., Schousboe, A. and Miledi, R. (1992) ‘Stereoselective effects of AMOA on non-NMDA receptors expressed in Xenopus oocytes’, J. Neurosci. Res. 33: 392-397.
-
(1992)
J. Neurosci. Res
, vol.33
, pp. 392-397
-
-
Wahl, P.1
Nielsen, B.2
Krogsgaard-Larsen, P.3
Hansen, J.J.4
Schousboe, A.5
Miledi, R.6
-
88
-
-
0030592145
-
Different characteristics of AMPA receptor agonists acting at AMPA receptors expressed in Xenopus oocytes
-
Wahl, P., Madsen, U., Banke, T., Krogsgaard-Larsen, P. and Schousboe, A. (1996) ‘Different characteristics of AMPA receptor agonists acting at AMPA receptors expressed in Xenopus oocytes’, Eur. J. Pharmacol. 308: 211-218.
-
(1996)
Eur. J. Pharmacol
, vol.308
, pp. 211-218
-
-
Wahl, P.1
Madsen, U.2
Banke, T.3
Krogsgaard-Larsen, P.4
Schousboe, A.5
-
89
-
-
0031965689
-
Antagonist properties of a phosphono isoxazole amino acid at glutamate R1-4 (R, S)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid receptor subtypes
-
Wahl, P., Anker, C., Traynelis, S.F., Egebjerg, J., Rasmussen, J.S., Krogsgaard-Larsen, P. and Madsen, U. (1998) ‘Antagonist properties of a phosphono isoxazole amino acid at glutamate R1-4 (R, S)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid receptor subtypes’, Mol. Pharmacol. 53: 590-596.
-
(1998)
Mol. Pharmacol
, vol.53
, pp. 590-596
-
-
Wahl, P.1
Anker, C.2
Traynelis, S.F.3
Egebjerg, J.4
Rasmussen, J.S.5
Krogsgaard-Larsen, P.6
Madsen, U.7
-
90
-
-
0027455788
-
Isatin oximes - a novel series of bioavailable non-NMDA antagonists
-
Wätjen, F., Nielsen, E.Ø., Drejer, J. and Jensen, L.H. (1993) ‘Isatin oximes - a novel series of bioavailable non-NMDA antagonists’, Bioorg. Med. Chem. Lett. 3: 105-106.
-
(1993)
Bioorg. Med. Chem. Lett
, vol.3
, pp. 105-106
-
-
Wätjen, F.1
Nielsen, E.Ø.2
Drejer, J.3
Jensen, L.H.4
-
91
-
-
0028269844
-
NS 257 (1,2,3,6,7,8-hexahydro-3-(hydroxyimino)-N, N,7-trimethyl-2-oxobenzo[2,1-b:3,4-c’]dipyrrole-5-sulfonamide) is a potent, systemically active AMPA receptor antagonist
-
Wätjen, F., Bigge, C.F., Jensen, L.H., Boxer, P.A., Lescosky, L.J., Nielsen, E.Ø., Malone, T.C., Campbell, G.W., Coughenour, L.L., Rock, D.M., Drejer, J. and Marcoux, F.W. (1994) ‘NS 257 (1,2,3,6,7,8-hexahydro-3-(hydroxyimino)-N, N,7-trimethyl-2-oxobenzo[2,1-b:3,4-c’]dipyrrole-5-sulfonamide) is a potent, systemically active AMPA receptor antagonist’, Bioorg. Med. Chem. Lett. 4: 371-376.
-
(1994)
Bioorg. Med. Chem. Lett
, vol.4
, pp. 371-376
-
-
Wätjen, F.1
Bigge, C.F.2
Jensen, L.H.3
Boxer, P.A.4
Lescosky, L.J.5
Nielsen, E.Ø.6
Malone, T.C.7
Campbell, G.W.8
Coughenour, L.L.9
Rock, D.M.10
Drejer, J.11
Marcoux, F.W.12
-
93
-
-
0025191432
-
Structure-activity relationships in the development of excitatory amino acid receptor agonists and competitive antagonists
-
Watkins, J.C., Krogsgaard-Larsen, P. and Honoré, T. (1990) ‘Structure-activity relationships in the development of excitatory amino acid receptor agonists and competitive antagonists’, Trends Pharmacol. Sci. 11: 25-33.
-
(1990)
Trends Pharmacol. Sci
, vol.11
, pp. 25-33
-
-
Watkins, J.C.1
Krogsgaard-Larsen, P.2
Honoré, T.3
-
94
-
-
0028988215
-
Differential antagonism of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-preferring and kainate-preferring receptors by 2,3-benzodiazepines
-
Wilding, T.J. and Huettner, J.E. (1995) ‘Differential antagonism of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-preferring and kainate-preferring receptors by 2,3-benzodiazepines’, Mol. Pharmacol. 47: 582-587.
-
(1995)
Mol. Pharmacol
, vol.47
, pp. 582-587
-
-
Wilding, T.J.1
Huettner, J.E.2
-
95
-
-
0025342419
-
Excitatory amino acid receptors in the brain: Membrane binding and receptor autoradiographic approaches
-
Young, A.B. and Fagg, G.E. (1990) ‘Excitatory amino acid receptors in the brain: membrane binding and receptor autoradiographic approaches’, Trends Pharmacol. Sci. 11: 126-133.
-
(1990)
Trends Pharmacol. Sci
, vol.11
, pp. 126-133
-
-
Young, A.B.1
Fagg, G.E.2
-
96
-
-
0027464959
-
A benzodiazepine recognition site associated with the non-NMDA glutamate receptor
-
Zorumski, C.F., Yamada, K.A., Price, M.T. and Olney, J.W. (1993) ‘A benzodiazepine recognition site associated with the non-NMDA glutamate receptor’, Neuron 10: 61-67.
-
(1993)
Neuron
, vol.10
, pp. 61-67
-
-
Zorumski, C.F.1
Yamada, K.A.2
Price, M.T.3
Olney, J.W.4
|