Excitatory amino-acid receptor agonists. Synthesis and pharmacology of analogues of 2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl) propionic acid.

European Journal of Medicinal Chemistry

Volumn 32, Issue 4, 1997, Pages 329-338

  Slok F A ^a   Ebert, B ^a   Lang, Y ^a   Krogsgaard Larsen, P ^a   Lenz, S M ^b   Madsen, U ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b H LUNDBECK A S   (Denmark)

Author keywords

AMPA agonist; AMPA receptor; Excitatory amino acid; Receptor binding; Structure activity studies

Indexed keywords

4 (3 PHOSPHONOPROPYL) 2 PIPERAZINECARBOXYLIC ACID; 6 NITRO 7 SULFAMOYLBENZO[F]QUINOXALINE 2,3 DIONE; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; AMPA RECEPTOR; AMPA RECEPTOR ANTAGONIST; KAINIC ACID;

ANIMAL TISSUE; ARTICLE; BINDING SITE; BRAIN CORTEX; CONTROLLED STUDY; DOSE RESPONSE; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; ELECTROPHYSIOLOGY; IN VITRO STUDY; NONHUMAN; RAT; STRUCTURE ACTIVITY RELATION;

EID: 0030995529     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0223-5234(97)89085-X     Document Type: Article

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