Allosteric regulation of α-amino-3-hydroxy-5-methyl-4-isoxazole- propionate receptors by thiocyanate and cyclothiazide at a common modulatory site distinct from that of 2,3-benzodiazepines

Neuroscience

Volumn 87, Issue 3, 1998, Pages 615-629

  Donevan, S D ^a,b   Rogawski, M A ^a  

^a Human Motor Control Section   (United States)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

2,3 benzodiazepine; AMPA receptor; Cyclothiazide; Desensitization; flip and flop; Thiocyanate

Indexed keywords

1 (4 AMINOPHENYL) 3,4 DIHYDRO 4 METHYL 3 METHYLCARBAMOYL 7,8 METHYLENEDIOXY 5H 2,3 BENZODIAZEPINE; 1 (4 AMINOPHENYL) 4 METHYL 7,8 METHYLENEDIOXY 5H 2,3 BENZODIAZEPINE; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; AMPA RECEPTOR; BENZODIAZEPINE DERIVATIVE; CYCLOTHIAZIDE; THIOCYANATE;

ALLOSTERISM; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG RECEPTOR BINDING; EMBRYO; HIPPOCAMPUS; ION CURRENT; NEUROMODULATION; NEUROTRANSMITTER RELEASE; NONHUMAN; OOCYTE; PRIORITY JOURNAL; RAT; RECEPTOR DOWN REGULATION;

ALLOSTERIC REGULATION; ANIMALS; ANTI-ANXIETY AGENTS; ANTIHYPERTENSIVE AGENTS; BENZODIAZEPINES; BENZOTHIADIAZINES; BINDING SITES; CELLS, CULTURED; EXCITATORY AMINO ACID AGONISTS; EXCITATORY AMINO ACID ANTAGONISTS; GAMMA-AMINOBUTYRIC ACID; HIPPOCAMPUS; ION CHANNEL GATING; KAINIC ACID; MEMBRANE POTENTIALS; N-METHYLASPARTATE; NEURONS; OOCYTES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, AMPA; THIOCYANATES; XENOPUS;

EID: 0032483107     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(98)00109-2     Document Type: Article

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