Identification of druggable targets for Acinetobacter baumannii via subtractive genomics and plausible inhibitors for MurA and MurB

Applied Biochemistry and Biotechnology

Volumn 171, Issue 2, 2013, Pages 417-436

  Kaur, Navkiran ^a   Khokhar, Mansimran ^a   Jain, Vaibhav ^b   Bharatam, P V ^b   Sandhir, Rajat ^a   Tewari, Rupinder ^a  

^a PANJAB UNIVERSITY   (India)

^b NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

Author keywords

Acinetobacter baumannii; Homology modeling; Molecular docking; Molecular dynamics; MurA; MurB; Peptidoglycan; Subtractive genomics

Indexed keywords

BAUMANNII; GENOMICS; HOMOLOGY MODELING; MOLECULAR DOCKING; MURA; MURB; PEPTIDOGLYCANS;

AMINO ACIDS; BINDING ENERGY; BIOCHEMISTRY; DRUG DELIVERY; DRUG PRODUCTS; HYDROGEN BONDS; LIGANDS; MOLECULAR DYNAMICS; PATHOGENS; PROTEINS;

ENZYMES;

BACTERIAL ENZYME; CARBIDOPA; ESCULIN; MURA ENZYME; MURB ENZYME; PEPTIDOGLYCAN; UNCLASSIFIED DRUG;

ACINETOBACTER BAUMANNII; ARTICLE; BIOSYNTHESIS; COMPUTER MODEL; DRUG DESIGN; DRUG TARGETING; GENOMICS; HYDROGEN BOND; MOLECULAR DYNAMICS; NONHUMAN;

ACINETOBACTER BAUMANNII; BACTERIA (MICROORGANISMS);

ACINETOBACTER BAUMANNII; ALKYL AND ARYL TRANSFERASES; ANTI-BACTERIAL AGENTS; DRUG DISCOVERY; ENZYME INHIBITORS; GENOMICS; METABOLIC NETWORKS AND PATHWAYS; MOLECULAR DOCKING SIMULATION; MOLECULAR DYNAMICS SIMULATION; PROTEIN CONFORMATION;

EID: 84883793397     PISSN: 02732289     EISSN: 15590291     Source Type: Journal    
DOI: 10.1007/s12010-013-0372-2     Document Type: Article

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