Identification and characterization of amino acid residues essential for the active site of UDP-N-acetylenolpyruvylglucosamine reductase (MurB) from Staphylococcus aureus

Journal of Biological Chemistry

Volumn 281, Issue 3, 2006, Pages 1714-1724

  Nishida, Satoshi ^a,c   Kurokawa, Kenji ^a   Matsuo, Miki ^a   Sakamoto, Kimitoshi ^b   Ueno, Kohji ^c   Kita, Kiyoshi ^c   Sekimizu, Kazuhisa ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c MUSASHINO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; CATALYSIS; CRYSTAL STRUCTURE; DRUG PRODUCTS; ENZYMES; GENES;

BIOCHEMICAL CHARACTERIZATION; ELECTRONIC STATE; PEPTIDOGLYCAN; X-RAY CRYSTAL STRUCTURES;

AMINO ACIDS;

AMINO ACID; ARGININE; BACTERIAL ENZYME; FLAVINE ADENINE NUCLEOTIDE; FLAVOPROTEIN; LIGAND; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; PEPTIDOGLYCAN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; UNCLASSIFIED DRUG; URIDINE DIPHOSPHATE; URIDINE DIPHOSPHATE N ACETYLENOLPYRUVYLGLUCOSAMINE REDUCTASE; BACTERIAL PROTEIN; OXIDOREDUCTASE; PRIMER DNA; RECOMBINANT PROTEIN; UDP N ACETYLMURAMATE DEHYDROGENASE; UDP-N-ACETYLMURAMATE DEHYDROGENASE;

ARTICLE; BACTERIAL GENE; CRYSTAL STRUCTURE; GENE OVEREXPRESSION; MURB GENE; NONHUMAN; PLASMID; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; STAPHYLOCOCCUS AUREUS; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; BINDING SITE; CHEMISTRY; ENZYMOLOGY; GENETICS; KINETICS; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY;

BACTERIA (MICROORGANISMS); STAPHYLOCOCCUS AUREUS;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; BACTERIAL PROTEINS; BASE SEQUENCE; BINDING SITES; CARBOHYDRATE DEHYDROGENASES; CONSERVED SEQUENCE; DNA PRIMERS; KINETICS; MOLECULAR SEQUENCE DATA; RECOMBINANT PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; STAPHYLOCOCCUS AUREUS;

EID: 33644986330     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M509277200     Document Type: Article

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