메뉴 건너뛰기




Volumn 23, Issue 5, 2013, Pages 188-197

Effect of BDNF Val66Met and serotonin transporter 5-HTTLPR polymorphisms on psychopathological characteristics in a sample of university students

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; SEROTONIN TRANSPORTER; SEROTONIN TRANSPORTER LINKED POLYMORPHIC REGION; UNCLASSIFIED DRUG;

EID: 84883653018     PISSN: 09558829     EISSN: 14735873     Source Type: Journal    
DOI: 10.1097/YPG.0b013e3283643629     Document Type: Article
Times cited : (6)

References (91)
  • 1
    • 67649964222 scopus 로고    scopus 로고
    • Early adversity and 5-HTT/BDNF genes: New evidence of gene-environment interactions on depressive symptoms in a general population
    • Aguilera M, Arias B, Wichers M., Barrantes-Vidal N, Moya J, Villa H., et al. (2009). Early adversity and 5-HTT/BDNF genes: new evidence of gene-environment interactions on depressive symptoms in a general population. Psychol Med 39:1425-1432.
    • (2009) Psychol Med , vol.39 , pp. 1425-1432
    • Aguilera, M.1    Arias, B.2    Wichers, M.3    Barrantes-Vidal, N.4    Moya, J.5    Villa, H.6
  • 3
    • 0042121277 scopus 로고    scopus 로고
    • A systematic review of association studies investigating genes coding for serotonin receptors and the serotonin transporter: II. Suicidal behavior
    • DOI 10.1038/sj.mp.4001336
    • Anguelova M, Benkelfat C, Turecki G. (2003). A systematic review of association studies investigating genes coding for serotonin receptors and the serotonin transporter: II. Suicidal behavior. Mol Psychiatry 8:646-653. (Pubitemid 36976297)
    • (2003) Molecular Psychiatry , vol.8 , Issue.7 , pp. 646-653
    • Anguelova, M.1    Benkelfat, C.2    Turecki, G.3
  • 4
    • 84856958685 scopus 로고    scopus 로고
    • The role of genetic variability in the SLC6A4, BDNF and GABRA6 genes in anxiety-related traits
    • Arias B, Aguilera M, Moya J., Saiz PA, Villa H, Ibanez MI, et al (2012). The role of genetic variability in the SLC6A4, BDNF and GABRA6 genes in anxiety-related traits. Acta Psychiatr Scand 125:194-202.
    • (2012) Acta Psychiatr Scand , vol.125 , pp. 194-202
    • Arias, B.1    Aguilera, M.2    Moya, J.3    Saiz, P.A.4    Villa, H.5    Ibanez, M.I.6
  • 6
    • 78751617979 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor and serotonin transporter gene-linked promoter region genes alter serum levels of brain-derived neurotrophic factor in humans
    • Bhang S, Ahn JH, Choi S.W. (2011). Brain-derived neurotrophic factor and serotonin transporter gene-linked promoter region genes alter serum levels of brain-derived neurotrophic factor in humans. J Affect Disord 128:299-304.
    • (2011) J Affect Disord , vol.128 , pp. 299-304
    • Bhang, S.1    Ahn, J.H.2    Choi, S.W.3
  • 9
  • 10
    • 79952673018 scopus 로고    scopus 로고
    • The 5-HTTLPR polymorphism and eating disorders: A meta-analysis
    • Calati R, De Ronchi D, Bellini M, Serretti A. (2011). The 5-HTTLPR polymorphism and eating disorders: a meta-analysis. Int J Eat Disord 44:191-199.
    • (2011) Int J Eat Disord , vol.44 , pp. 191-199
    • Calati, R.1    De Ronchi, D.2    Bellini, M.3    Serretti, A.4
  • 12
    • 14844298782 scopus 로고    scopus 로고
    • Is mood chemistry?
    • DOI 1038/nrn1629
    • Castren E (2005). Is mood chemistry? Nat Rev Neurosci 6:241-246. (Pubitemid 40342418)
    • (2005) Nature Reviews Neuroscience , vol.6 , Issue.3 , pp. 241-246
    • Castren, E.1
  • 14
    • 2342550552 scopus 로고    scopus 로고
    • Variant Brain-Derived Neurotrophic Factor (BDNF) (Met66) Alters the Intracellular Trafficking and Activity-Dependent Secretion of Wild-Type BDNF in Neurosecretory Cells and Cortical Neurons
    • DOI 10.1523/JNEUROSCI.0348-04.2004
    • Chen ZY, Patel PD, Sant G, Meng C.X., Teng KK, Hempstead BL, Lee F.S. (2004). Variant brain-derived neurotrophic factor (BDNF) (Met66) alters the intracellular trafficking and activity-dependent secretion of wild-type BDNF in neurosecretory cells and cortical neurons. J Neurosci 24:4401-4411. (Pubitemid 38608151)
    • (2004) Journal of Neuroscience , vol.24 , Issue.18 , pp. 4401-4411
    • Chen, Z.-Y.1    Patel, P.D.2    Sant, G.3    Meng, C.-X.4    Teng, K.K.5    Hempstead, B.L.6    Lee, F.S.7
  • 15
    • 59949101593 scopus 로고    scopus 로고
    • Effects of the brain-derived neurotrophic growth factor val66met variation on hippocampus morphology in bipolar disorder
    • Chepenik LG, Fredericks C, Papademetris X., Spencer L, Lacadie C, Wang F., et al. (2009). Effects of the brain-derived neurotrophic growth factor val66met variation on hippocampus morphology in bipolar disorder. Neuropsychopharmacology 34:944-951.
    • (2009) Neuropsychopharmacology , vol.34 , pp. 944-951
    • Chepenik, L.G.1    Fredericks, C.2    Papademetris, X.3    Spencer, L.4    Lacadie, C.5    Wang, F.6
  • 17
    • 78650308693 scopus 로고    scopus 로고
    • Association of the 5-HTTLPR genotype and unipolar depression: A meta-analysis
    • Clarke H, Flint J, Attwood A.S., Munafo M.R. (2010). Association of the 5-HTTLPR genotype and unipolar depression: a meta-analysis. Psychol Med 40: 1767-1778.
    • (2010) Psychol Med , vol.40 , pp. 1767-1778
    • Clarke, H.1    Flint, J.2    Attwood, A.S.3    Munafo, M.R.4
  • 18
    • 84866286536 scopus 로고    scopus 로고
    • Essential role of brain-derived neurotrophic factor in the regulation of serotonin transmission in the basolateral amygdala
    • Daftary SS, Calderon G, Rios M. (2012). Essential role of brain-derived neurotrophic factor in the regulation of serotonin transmission in the basolateral amygdala. Neuroscience 224:125-134.
    • (2012) Neuroscience , vol.224 , pp. 125-134
    • Daftary, S.S.1    Calderon, G.2    Rios, M.3
  • 20
    • 0040950682 scopus 로고
    • The eysenck personality questionnaire (EPQ). The validity of the greek, adult and junior version
    • Dimitriou E (1986). The Eysenck Personality Questionnaire (EPQ). The validity of the Greek, adult and junior version. Engefalos 12:41-54.
    • (1986) Engefalos , vol.12 , pp. 41-54
    • Dimitriou, E.1
  • 21
    • 0002515026 scopus 로고
    • Standardization of the symptom checklist-90-R rating scale in a greek population
    • Donias S, Karastergiou A, Manos N. (1991). Standardization of the symptom checklist-90-R rating scale in a Greek population. Psychiatriki 2:42-48.
    • (1991) Psychiatriki , vol.2 , pp. 42-48
    • Donias, S.1    Karastergiou, A.2    Manos, N.3
  • 22
    • 62649103330 scopus 로고    scopus 로고
    • Variation in brain-derived neurotrophic factor (BDNF) gene is associated with symptoms of depression
    • Duncan LE, Hutchison KE, Carey G, Craighead W.E. (2009). Variation in brain-derived neurotrophic factor (BDNF) gene is associated with symptoms of depression. J Affect Disord 115 (1-2):215-219.
    • (2009) J Affect Disord , vol.115 , Issue.1-2 , pp. 215-219
    • Duncan, L.E.1    Hutchison, K.E.2    Carey, G.3    Craighead, W.E.4
  • 25
    • 0345901465 scopus 로고    scopus 로고
    • Reliability, validity and psychometric properties of the greek translation of the center for epidemiological studies-depression (CES-D) scale
    • Fountoulakis K, Iacovides A, Kleanthous S., Samolis S, Kaprinis SG, Sitzoglou K, et al (2001). Reliability, validity and psychometric properties of the Greek translation of the Center for Epidemiological Studies-Depression (CES-D) Scale. BMC Psychiatry 1:3.
    • (2001) BMC Psychiatry , vol.1 , pp. 3
    • Fountoulakis, K.1    Iacovides, A.2    Kleanthous, S.3    Samolis, S.4    Kaprinis, S.G.5    Sitzoglou, K.6
  • 27
    • 55349093982 scopus 로고    scopus 로고
    • Reduced hippocampal volumes associated with the long variant of the tri-and diallelic serotonin transporter polymorphism in major depression
    • Frodl T, Zill P, Baghai T., Schule C, Rupprecht R, Zetzsche T., et al. (2008). Reduced hippocampal volumes associated with the long variant of the tri-and diallelic serotonin transporter polymorphism in major depression. Am J Med Genet B Neuropsychiatr Genet 147B:1003-1007.
    • (2008) Am J Med Genet B Neuropsychiatr Genet , vol.147 B , pp. 1003-1007
    • Frodl, T.1    Zill, P.2    Baghai, T.3    Schule, C.4    Rupprecht, R.5    Zetzsche, T.6
  • 28
    • 57649107434 scopus 로고    scopus 로고
    • Meta-analysis of the brain-derived neurotrophic factor gene (BDNF) val66met polymorphism in anxiety disorders and anxiety-related personality traits
    • Frustaci A, Pozzi G, Gianfagna F., Manzoli L, Boccia S. (2008). Meta-analysis of the brain-derived neurotrophic factor gene (BDNF) Val66Met polymorphism in anxiety disorders and anxiety-related personality traits. Neuropsychobiology 58 (3-4):163-170.
    • (2008) Neuropsychobiology , vol.58 , Issue.3-4 , pp. 163-170
    • Frustaci, A.1    Pozzi, G.2    Gianfagna, F.3    Manzoli, L.4    Boccia, S.5
  • 29
    • 4444322215 scopus 로고    scopus 로고
    • Linkage disequilibrium of the brain-derived neurotrophic factor Val66Met polymorphism in children with a prepubertal and early adolescent bipolar disorder phenotype
    • DOI 10.1176/appi.ajp.161.9.1698
    • Geller B, Badner JA, Tillman R, Christian S.L., Bolhofner K., Cook EH Jr (2004). Linkage disequilibrium of the brain-derived neurotrophic factor Val66Met polymorphism in children with a prepubertal and early adolescent bipolar disorder phenotype. Am J Psychiatry 161:1698-1700. (Pubitemid 39201469)
    • (2004) American Journal of Psychiatry , vol.161 , Issue.9 , pp. 1698-1700
    • Geller, B.1    Badner, J.A.2    Tillman, R.3    Christian, S.L.4    Bolhofner, K.5    Cook Jr., E.H.6
  • 30
    • 0037494707 scopus 로고    scopus 로고
    • Serotonin transporter gene polymorphism and schizoid personality traits in the patients with psychosis and psychiatrically well subjects
    • Golimbet VE, Alfimova MV, Shcherbatikh T, Kaleda V.G., Abramova LI, Rogaev E.I. (2003). Serotonin transporter gene polymorphism and schizoid personality traits in the patients with psychosis and psychiatrically well subjects. World J Biol Psychiatry 4:25-29.
    • (2003) World J Biol Psychiatry , vol.4 , pp. 25-29
    • Golimbet, V.E.1    Alfimova, M.V.2    Shcherbatikh, T.3    Kaleda, V.G.4    Abramova, L.I.5    Rogaev, E.I.6
  • 31
    • 84855354000 scopus 로고    scopus 로고
    • Genetic epistasis between the brain-derived neurotrophic factor val66met polymorphism and the 5-HTT promoter polymorphism moderates the susceptibility to depressive disorders after childhood abuse
    • Grabe HJ, Schwahn C, Mahler J., Appel K, Schulz A, Spitzer C., et al. (2012). Genetic epistasis between the brain-derived neurotrophic factor Val66Met polymorphism and the 5-HTT promoter polymorphism moderates the susceptibility to depressive disorders after childhood abuse. Prog Neuropsycho-pharmacol Biol Psychiatry 36 (2-3):264-270.
    • (2012) Prog Neuropsycho-pharmacol Biol Psychiatry , vol.36 , Issue.2-3 , pp. 264-270
    • Grabe, H.J.1    Schwahn, C.2    Mahler, J.3    Appel, K.4    Schulz, A.5    Spitzer, C.6
  • 32
    • 33947235663 scopus 로고    scopus 로고
    • Brain-Derived Neurotrophic Factor Val66Met and Psychiatric Disorders: Meta-Analysis of Case-Control Studies Confirm Association to Substance-Related Disorders, Eating Disorders, and Schizophrenia
    • DOI 10.1016/j.biopsych.2006.08.025, PII S0006322306010729
    • Gratacos M, Gonzalez JR, Mercader J.M., De Cid R, Urretavizcaya M, Estivill X. (2007). Brain-derived neurotrophic factor Val66Met and psychiatric disorders: meta-analysis of case-control studies confirm association to substance-related disorders, eating disorders, and schizophrenia. Biol Psychiatry 61:911-922. (Pubitemid 46420580)
    • (2007) Biological Psychiatry , vol.61 , Issue.7 , pp. 911-922
    • Gratacos, M.1    Gonzalez, J.R.2    Mercader, J.M.3    De Cid, R.4    Urretavizcaya, M.5    Estivill, X.6
  • 34
    • 33750044049 scopus 로고    scopus 로고
    • Association study of the 5-HTTLPR polymorphism and depression in 75-year-old nondemented subjects from the Vienna Transdanube Aging (VITA) study
    • Grunblatt E, Loffler C, Zehetmayer S., Jungwirth S, Tragl KH, Riederer P, Fischer P. (2006). Association study of the 5-HTTLPR polymorphism and depression in 75-year-old nondemented subjects from the Vienna Transdanube Aging (VITA) study. J Clin Psychiatry 670:1373-1378. (Pubitemid 44583384)
    • (2006) Journal of Clinical Psychiatry , vol.67 , Issue.9 , pp. 1373-1378
    • Grunblatt, E.1    Loffler, C.2    Zehetmayer, S.3    Jungwirth, S.4    Tragl, K.-H.5    Riederer, P.6    Fischer, P.7
  • 36
    • 84875210968 scopus 로고    scopus 로고
    • Genome-wide association data provide further support for an association between 5-HTTLPR and major depressive disorder
    • Haenisch B, Herms S, Mattheisen M., Steffens M, Breuer R, Strohmaier J., et al. (2013). Genome-wide association data provide further support for an association between 5-HTTLPR and major depressive disorder. J Affect Disord 146:438-440.
    • (2013) J Affect Disord , vol.146 , pp. 438-440
    • Haenisch, B.1    Herms, S.2    Mattheisen, M.3    Steffens, M.4    Breuer, R.5    Strohmaier, J.6
  • 37
    • 0042165043 scopus 로고    scopus 로고
    • Sequence variants of the brain-derived neurotrophic factor (BDNF) gene are strongly associated with obsessive-compulsive disorder
    • DOI 10.1086/377003
    • Hall D, Dhilla A, Charalambous A., Gogos JA, Karayiorgou M. (2003). Sequence variants of the brain-derived neurotrophic factor (BDNF) gene are strongly associated with obsessive-compulsive disorder. Am J Hum Genet 73: 370-376. (Pubitemid 36920998)
    • (2003) American Journal of Human Genetics , vol.73 , Issue.2 , pp. 370-376
    • Hall, D.1    Dhilla, A.2    Charalambous, A.3    Gogos, J.A.4    Karayiorgou, M.5
  • 38
    • 33645799676 scopus 로고    scopus 로고
    • Genetics of emotional regulation: The role of the serotonin transporter in neural function
    • Hariri AR, Holmes A. (2006). Genetics of emotional regulation: the role of the serotonin transporter in neural function. Trends Cogn Sci 4:182-191.
    • (2006) Trends Cogn Sci , vol.4 , pp. 182-191
    • Hariri, A.R.1    Holmes, A.2
  • 40
    • 77955078119 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor as a biomarker for mood disorders: An historical overview and future directions
    • Hashimoto K (2010). Brain-derived neurotrophic factor as a biomarker for mood disorders: an historical overview and future directions. Psychiatry Clin Neurosci 64:341-357.
    • (2010) Psychiatry Clin Neurosci , vol.64 , pp. 341-357
    • Hashimoto, K.1
  • 41
    • 0031435392 scopus 로고    scopus 로고
    • The human serotonin transporter gene polymorphism-basic research and clinical implications
    • DOI 10.1007/BF01273314
    • Heils A, Mossner R, Lesch K.P. (1997). The human serotonin transporter gene polymorphism - basic research and clinical implications. J Neural Transm 104:1005-1014. (Pubitemid 28031667)
    • (1997) Journal of Neural Transmission , vol.104 , Issue.10 , pp. 1005-1014
    • Heils, A.1    Mossner, R.2    Lesch, K.P.3
  • 43
    • 33646072813 scopus 로고    scopus 로고
    • Serotonin transporter promoter gain-of-function genotypes are linked to obsessive-compulsive disorder
    • Hu XZ, Lipsky RH, Zhu G, Akhtar L.A., Taubman J., Greenberg BD, et al (2006). Serotonin transporter promoter gain-of-function genotypes are linked to obsessive-compulsive disorder. Am J Hum Genet 78:815-826.
    • (2006) Am J Hum Genet , vol.78 , pp. 815-826
    • Hu, X.Z.1    Lipsky, R.H.2    Zhu, G.3    Akhtar, L.A.4    Taubman, J.5    Greenberg, B.D.6
  • 44
    • 36248971736 scopus 로고    scopus 로고
    • Interaction between BDNF Val66Met and dopamine transporter gene variation influences anxiety-related traits
    • DOI 10.1038/sj.npp.1301383, PII 1301383
    • Hunnerkopf R, Strobel A, Gutknecht L., Brocke B, Lesch K.P. (2007). Interaction between BDNF Val66Met and dopamine transporter gene variation influences anxiety-related traits. Neuropsychopharmacology 32:2552-2560. (Pubitemid 350126836)
    • (2007) Neuropsychopharmacology , vol.32 , Issue.12 , pp. 2552-2560
    • Hunnerkopf, R.1    Strobel, A.2    Gutknecht, L.3    Brocke, B.4    Lesch, K.P.5
  • 46
    • 0036202956 scopus 로고    scopus 로고
    • Decreased serum brain-derived neurotrophic factor levels in major depressed patients
    • DOI 10.1016/S0165-1781(02)00005-7, PII S0165178102000057
    • Karege F, Perret G, Bondolfi G., Schwald M, Bertschy G, Aubry J.M. (2002). Decreased serum brain-derived neurotrophic factor levels in major depressed patients. Psychiatry Res 109:143-148. (Pubitemid 34258493)
    • (2002) Psychiatry Research , vol.109 , Issue.2 , pp. 143-148
    • Karege, F.1    Perret, G.2    Bondolfi, G.3    Schwald, M.4    Bertschy, G.5    Aubry, J.-M.6
  • 47
    • 33645337891 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor-5-HTTLPR gene interactions and environmental modifiers of depression in children
    • Kaufman J, Yang BZ, Douglas-Palumberi H, Grasso D., Lipschitz D, Houshyar S, et al (2006). Brain-derived neurotrophic factor-5-HTTLPR gene interactions and environmental modifiers of depression in children. Biol Psychiatry 59:673-680.
    • (2006) Biol Psychiatry , vol.59 , pp. 673-680
    • Kaufman, J.1    Yang, B.Z.2    Douglas-Palumberi, H.3    Grasso, D.4    Lipschitz, D.5    Houshyar, S.6
  • 48
    • 18244389951 scopus 로고    scopus 로고
    • The interaction of stressful life events and a serotonin transporter polymorphism in the prediction of episodes of major depression: A replication
    • DOI 10.1001/archpsyc.62.5.529
    • Kendler KS, Kuhn JW, Vittum J, Prescott C.A., Riley B. (2005). The interaction of stressful life events and a serotonin transporter polymorphism in the prediction of episodes of major depression: a replication. Arch Gen Psychiatry 62:529-535. (Pubitemid 40628882)
    • (2005) Archives of General Psychiatry , vol.62 , Issue.5 , pp. 529-535
    • Kendler, K.S.1    Kuhn, J.W.2    Vittum, J.3    Prescott, C.A.4    Riley, B.5
  • 49
    • 34548021027 scopus 로고    scopus 로고
    • Interactions Between Life Stressors and Susceptibility Genes (5-HTTLPR and BDNF) on Depression in Korean Elders
    • DOI 10.1016/j.biopsych.2006.11.020, PII S0006322306015095
    • Kim JM, Stewart R, Kim S.W., Yang SJ, Shin IS, Kim YH, Yoon J.S. (2007). Interactions between life stressors and susceptibility genes (5-HTTLPR and BDNF) on depression in Korean elders. Biol Psychiatry 62:423-428. (Pubitemid 47284032)
    • (2007) Biological Psychiatry , vol.62 , Issue.5 , pp. 423-428
    • Kim, J.-M.1    Stewart, R.2    Kim, S.-W.3    Yang, S.-J.4    Shin, I.-S.5    Kim, Y.-H.6    Yoon, J.-S.7
  • 50
    • 70449671191 scopus 로고    scopus 로고
    • Interaction between brain-derived neurotrophic factor val66met polymorphism and recent negative stressor in harm avoidance
    • Kim SJ, Cho SJ, Jang H.M., Shin J., Park PW, Lee YJ, et al (2010). Interaction between brain-derived neurotrophic factor Val66Met polymorphism and recent negative stressor in harm avoidance. Neuropsychobiology 61:19-26.
    • (2010) Neuropsychobiology , vol.61 , pp. 19-26
    • Kim, S.J.1    Cho, S.J.2    Jang, H.M.3    Shin, J.4    Park, P.W.5    Lee, Y.J.6
  • 51
    • 77955267304 scopus 로고    scopus 로고
    • Changes in 5-HT2A-mediated behavior and 5-HT2A-and 5-HT1A receptor binding and expression in conditional brain-derived neurotrophic factor knock-out mice
    • Klein AB, Santini MA, Aznar S, Knudsen G.M., Rios M. (2010). Changes in 5-HT2A-mediated behavior and 5-HT2A-and 5-HT1A receptor binding and expression in conditional brain-derived neurotrophic factor knock-out mice. Neuroscience 169:1007-1016.
    • (2010) Neuroscience , vol.169 , pp. 1007-1016
    • Klein, A.B.1    Santini, M.A.2    Aznar, S.3    Knudsen, G.M.4    Rios, M.5
  • 54
    • 65549105390 scopus 로고    scopus 로고
    • Novel sequence variations in the brain-derived neurotrophic factor gene and association with major depression and antidepressant treatment response
    • Licinio J, Dong C, Wong M.L. (2009). Novel sequence variations in the brain-derived neurotrophic factor gene and association with major depression and antidepressant treatment response. Arch Gen Psychiatry 66:488-497.
    • (2009) Arch Gen Psychiatry , vol.66 , pp. 488-497
    • Licinio, J.1    Dong, C.2    Wong, M.L.3
  • 58
    • 36549042458 scopus 로고    scopus 로고
    • Interaction between BDNF and serotonin: Role in mood disorders
    • DOI 10.1038/sj.npp.1301571, PII 1301571
    • Martinowich K, Lu B. (2008). Interaction between BDNF and serotonin: role in mood disorders. Neuropsychopharmacology 33:73-83. (Pubitemid 350191318)
    • (2008) Neuropsychopharmacology , vol.33 , Issue.1 , pp. 73-83
    • Martinowich, K.1    Lu, B.2
  • 62
    • 0032890036 scopus 로고    scopus 로고
    • An immunohistochemical study of the distribution of brain-derived neurotrophic factor in the adult human brain, with particular reference to Alzheimer's disease
    • DOI 10.1016/S0306-4522(98)00219-X, PII S030645229800219X
    • Murer MG, Boissiere F, Yan Q., Hunot S, Villares J, Faucheux B., et al. (1999). An immunohistochemical study of the distribution of brain-derived neurotrophic factor in the adult human brain, with particular reference to Alzheimer's disease. Neuroscience 88:1015-1032. (Pubitemid 28546985)
    • (1999) Neuroscience , vol.88 , Issue.4 , pp. 1015-1032
    • Murer, M.G.1    Boissiere, F.2    Yan, Q.3    Hunot, S.4    Villares, J.5    Faucheux, B.6    Agid, Y.7    Hirsch, E.8    Raisman-Vozari, R.9
  • 63
    • 77954214296 scopus 로고    scopus 로고
    • Interaction between childhood adversity, brain-derived neurotrophic factor val/met and serotonin transporter promoter polymorphism on depression: The TRAILS study
    • Nederhof E, Bouma EM, Oldehinkel A.J., Ormel J. (2010). Interaction between childhood adversity, brain-derived neurotrophic factor val/met and serotonin transporter promoter polymorphism on depression: the TRAILS study. Biol Psychiatry 68:209-212.
    • (2010) Biol Psychiatry , vol.68 , pp. 209-212
    • Nederhof, E.1    Bouma, E.M.2    Oldehinkel, A.J.3    Ormel, J.4
  • 65
    • 0036724341 scopus 로고    scopus 로고
    • The brain-derived neurotrophic factor gene confers susceptibility to bipolar disorder: Evidence from a family-based association study
    • DOI 10.1086/342288
    • Neves-Pereira M., Mundo E, Muglia P., King N, Macciardi F, Kennedy J.L. (2002). The brain-derived neurotrophic factor gene confers susceptibility to bipolar disorder: evidence from a family-based association study. Am J Hum Genet 71:651-655. (Pubitemid 34970137)
    • (2002) American Journal of Human Genetics , vol.71 , Issue.3 , pp. 651-655
    • Neves-Pereira, M.1    Mundo, E.2    Muglia, P.3    King, N.4    Macciardi, F.5    Kennedy, J.L.6
  • 66
    • 79952282874 scopus 로고    scopus 로고
    • Gene-environment interactions: Early life stress and risk for depressive and anxiety disorders
    • Nugent NR, Tyrka AR, Carpenter L.L., Price L.H. (2011). Gene-environment interactions: early life stress and risk for depressive and anxiety disorders. Psychopharmacology (Berl) 214:175-196.
    • (2011) Psychopharmacology (Berl) , vol.214 , pp. 175-196
    • Nugent, N.R.1    Tyrka, A.R.2    Carpenter, L.L.3    Price, L.H.4
  • 67
    • 24044439736 scopus 로고    scopus 로고
    • No implication of brain-derived neurotrophic factor (BDNF) gene in unipolar affective disorder: Evidence from Belgian first and replication patient-control studies
    • DOI 10.1016/j.euroneuro.2005.01.001, PII S0924977X05000325
    • Oswald P, Del-Favero J, Massat I., Souery D, Claes S, Van Broeckhoven C, Mendlewicz J (2005). No implication of brain-derived neurotrophic factor (BDNF) gene in unipolar affective disorder: evidence from Belgian first and replication patient-control studies. Eur Neuropsychopharmacol 15: 491-495. (Pubitemid 41219618)
    • (2005) European Neuropsychopharmacology , vol.15 , Issue.5 , pp. 491-495
    • Oswald, P.1    Del-Favero, J.2    Massat, I.3    Souery, D.4    Claes, S.5    Van Broeckhoven, C.6    Mendlewicz, J.7
  • 71
    • 36549030795 scopus 로고    scopus 로고
    • Stress, depression, and neuroplasticity: A convergence of mechanisms
    • DOI 10.1038/sj.npp.1301574, PII 1301574
    • Pittenger C, Duman R.S. (2008). Stress, depression, and neuroplasticity: a convergence of mechanisms. Neuropsychopharmacology 33:88-109. (Pubitemid 350191319)
    • (2008) Neuropsychopharmacology , vol.33 , Issue.1 , pp. 88-109
    • Pittenger, C.1    Duman, R.S.2
  • 72
    • 0035234670 scopus 로고    scopus 로고
    • Neurotrophins as synaptic modulators
    • Poo MM (2001). Neurotrophins as synaptic modulators. Nat Rev Neurosci 2:24-32.
    • (2001) Nat Rev Neurosci , vol.2 , pp. 24-32
    • Poo, M.M.1
  • 73
    • 16444364771 scopus 로고    scopus 로고
    • Loss of brain-derived neurotrophic factor gene allele exacerbates brain monoamine deficiencies and increases stress abnormalities of serotonin transporter knockout mice
    • DOI 10.1002/jnr.20410
    • Ren-Patterson R.F., Cochran LW, Holmes A, Sherrill S., Huang SJ, Tolliver T, et al (2005). Loss of brain-derived neurotrophic factor gene allele exacerbates brain monoamine deficiencies and increases stress abnormalities of serotonin transporter knockout mice. J Neurosci Res 79:756-771. (Pubitemid 40476500)
    • (2005) Journal of Neuroscience Research , vol.79 , Issue.6 , pp. 756-771
    • Ren-Patterson, R.F.1    Cochran, L.W.2    Holmes, A.3    Sherrill, S.4    Huang, S.-J.5    Tolliver, T.6    Lesch, K.-P.7    Lu, B.8    Murphy, D.L.9
  • 74
    • 34447544142 scopus 로고    scopus 로고
    • The brain-derived neurotrophic factor rs6265 (Val66Met) polymorphism and depression in Mexican-Americans
    • DOI 10.1097/WNR.0b013e328273bcb0, PII 0000175620070806000018
    • Ribeiro L, Busnello JV, Cantor R.M., Whelan F., Whittaker P, Deloukas P, et al (2007). The brain-derived neurotrophic factor rs6265 (Val66Met) polymorphism and depression in Mexican-Americans. Neuroreport 18:1291-1293. (Pubitemid 47075599)
    • (2007) NeuroReport , vol.18 , Issue.12 , pp. 1291-1293
    • Ribeiro, L.1    Busnello, J.V.2    Cantor, R.M.3    Whelan, F.4    Whittaker, P.5    Deloukas, P.6    Wong, M.-L.7    Licinio, J.8
  • 75
    • 0034792085 scopus 로고    scopus 로고
    • Conditional deletion of brain-derived neurotrophic factor in the postnatal brain leads to obesity and hyperactivity
    • DOI 10.1210/me.15.10.1748
    • Rios M, Fan G, Fekete C., Kelly J, Bates B, Kuehn R., et al. (2001). Conditional deletion of brain-derived neurotrophic factor in the postnatal brain leads to obesity and hyperactivity. Mol Endocrinol 15:1748-1757. (Pubitemid 32939305)
    • (2001) Molecular Endocrinology , vol.15 , Issue.10 , pp. 1748-1757
    • Rios, M.1    Guoping, F.A.N.2    Fekete, C.3    Kelly, J.4    Bates, B.5    Kuehn, R.6    Lechan, R.M.7    Jaenisch, R.8
  • 76
    • 0036364912 scopus 로고    scopus 로고
    • Catechol O-methyltransferase, serotonin transporter, and tryptophan hydroxylase gene polymorphisms in bipolar disorder patients with and without comorbid panic disorder
    • DOI 10.1176/appi.ajp.159.1.23
    • Rotondo A, Mazzanti C, Dell'Osso L, Rucci P, Sullivan P, Bouanani S, et al. (2002). Catechol o-methyltransferase, serotonin transporter, and tryptophan hydroxylase gene polymorphisms in bipolar disorder patients with and without comorbid panic disorder. Am J Psychiatry 159:23-29. (Pubitemid 41070722)
    • (2002) American Journal of Psychiatry , vol.159 , Issue.1 , pp. 23-29
    • Rotondo, A.1    Mazzanti, C.2    Dell'Osso, L.3    Rucci, P.4    Sullivan, P.5    Bouanani, S.6    Gonnelli, C.7    Goldman, D.8    Cassano, G.B.9
  • 78
    • 0037310231 scopus 로고    scopus 로고
    • A BDNF coding variant is associated with the NEO personality inventory domain neuroticism, a risk factor for depression
    • Sen S, Nesse RM, Stoltenberg S.F., Li S., Gleiberman L, Chakravarti A, et al (2003). A BDNF coding variant is associated with the NEO personality inventory domain neuroticism, a risk factor for depression. Neuropsycho- pharmacology 28:397-401.
    • (2003) Neuropsycho-pharmacology , vol.28 , pp. 397-401
    • Sen, S.1    Nesse, R.M.2    Stoltenberg, S.F.3    Li, S.4    Gleiberman, L.5    Chakravarti, A.6
  • 82
    • 79955811339 scopus 로고    scopus 로고
    • Association between C-281A and val66met functional polymorphisms of BDNF gene and risk of recurrent major depressive disorder in polish population
    • Suchanek R, Owczarek A, Kowalczyk M., Kuci K, Kowalski J. (2011). Association between C-281A and val66met functional polymorphisms of BDNF gene and risk of recurrent major depressive disorder in Polish population. J Mol Neurosci 43:524-530.
    • (2011) J Mol Neurosci , vol.43 , pp. 524-530
    • Suchanek, R.1    Owczarek, A.2    Kowalczyk, M.3    Kuci, K.4    Kowalski, J.5
  • 83
    • 77949541540 scopus 로고    scopus 로고
    • BDNF val66met is associated with introversion and interacts with 5-HTTLPR to influence neuroticism
    • Terracciano A, Tanaka T, Sutin A.R., Deiana B., Balaci L, Sanna S, et al (2010). BDNF Val66Met is associated with introversion and interacts with 5-HTTLPR to influence neuroticism. Neuropsychopharmacology 35:1083-1089.
    • (2010) Neuropsychopharmacology , vol.35 , pp. 1083-1089
    • Terracciano, A.1    Tanaka, T.2    Sutin, A.R.3    Deiana, B.4    Balaci, L.5    Sanna, S.6
  • 84
    • 38349150151 scopus 로고    scopus 로고
    • The moderation by the serotonin transporter gene of environmental adversity in the aetiology of mental illness: Review and methodological analysis
    • Uher R, McGuffin P. (2008). The moderation by the serotonin transporter gene of environmental adversity in the aetiology of mental illness: review and methodological analysis. Mol Psychiatry 13:131-146.
    • (2008) Mol Psychiatry , vol.13 , pp. 131-146
    • Uher, R.1    McGuffin, P.2
  • 85
    • 63049130126 scopus 로고    scopus 로고
    • Psychological vulnerability differences in students - Carriers or not of the serotonin transporter promoter allele S: Effect of adverse experiences
    • Veletza S, Samakouri M, Emmanouil G., Trypsianis G, Kourmouli N, Livaditis M. (2009). Psychological vulnerability differences in students - carriers or not of the serotonin transporter promoter allele S: effect of adverse experiences. Synapse 63:193-200.
    • (2009) Synapse , vol.63 , pp. 193-200
    • Veletza, S.1    Samakouri, M.2    Emmanouil, G.3    Trypsianis, G.4    Kourmouli, N.5    Livaditis, M.6
  • 87
    • 77956264472 scopus 로고    scopus 로고
    • Serotonin transporter and BDNF genetic variants interact to predict cognitive reactivity in healthy adults
    • Wells TT, Beevers CG, McGeary J.E. (2010). Serotonin transporter and BDNF genetic variants interact to predict cognitive reactivity in healthy adults. J Affect Disord 126 (1-2):223-229.
    • (2010) J Affect Disord , vol.126 , Issue.1-2 , pp. 223-229
    • Wells, T.T.1    Beevers, C.G.2    McGeary, J.E.3
  • 89
    • 27544495491 scopus 로고    scopus 로고
    • The Val66Met coding variant of the brain-derived neurotrophic factor (BDNF) gene does not contribute toward variation in the personality trait neuroticism
    • DOI 10.1016/j.biopsych.2005.05.014, PII S0006322305005901
    • Willis-Owen S.A., Fullerton J, Surtees P.G., Wainwright NW, Miller S, Flint J. (2005). The Val66Met coding variant of the brain-derived neurotrophic factor (BDNF) gene does not contribute toward variation in the personality trait neuroticism. Biol Psychiatry 58:738-742. (Pubitemid 41547242)
    • (2005) Biological Psychiatry , vol.58 , Issue.9 , pp. 738-742
    • Willis-Owen, S.A.G.1    Fullerton, J.2    Surtees, P.G.3    Wainwright, N.W.J.4    Miller, S.5    Flint, J.6
  • 90
    • 85047697355 scopus 로고    scopus 로고
    • Association of a triallelic seroton in transporter gene promoter region (5-HTTLPR) polymorphism with stressful life events and severity of depression
    • DOI 10.1176/appi.ajp.163.9.1588
    • Zalsman G, Huang YY, Oquendo M.A., Burke AK, Hu XZ, Brent DA, et al (2006). Association of a triallelic serotonin transporter gene promoter region (5-HTTLPR) polymorphism with stressful life events and severity of depression. Am J Psychiatry 163:1588-1593. (Pubitemid 44465760)
    • (2006) American Journal of Psychiatry , vol.163 , Issue.9 , pp. 1588-1593
    • Zalsman, G.1    Huang, Y.-Y.2    Oquendo, M.A.3    Burke, A.K.4    Hu, X.-Z.5    Brent, D.A.6    Ellis, S.P.7    Goldman, D.8    Mann, J.J.9
  • 91
    • 76549189227 scopus 로고
    • A self-rating depression scale
    • Zung WW (1965). A Self-Rating Depression Scale. Arch Gen Psychiatry 12: 63-70.
    • (1965) Arch Gen Psychiatry , vol.12 , pp. 63-70
    • Zung, W.W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.