Association between C-281A and Val66met functional polymorphisms of BDNF gene and risk of recurrent major depressive disorder in Polish population

Journal of Molecular Neuroscience

Volumn 43, Issue 3, 2011, Pages 524-530

  Suchanek, Renata ^a   Owczarek, Aleksander ^a   Kowalczyk, Małgorzata ^a   Kucia, Krzysztof ^a   Kowalski, Jan ^a  

^a MEDICAL UNIVERSITY OF SILESIA   (Poland)

Author keywords

Association study; BDNF; C 281A; Polymorphism; Recurrent major depression; Val66met

Indexed keywords

ALANINE; BRAIN DERIVED NEUROTROPHIC FACTOR; CYSTEINE; METHIONINE; VALINE;

ADULT; ALLELE; ARTICLE; CASE CONTROL STUDY; CONTROLLED STUDY; DNA POLYMORPHISM; FEMALE; GENE LINKAGE DISEQUILIBRIUM; GENOTYPE; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MALE; NUCLEOTIDE SEQUENCE; POLAND; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RISK FACTOR; SEX DIFFERENCE; SEX RATIO; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; AGED; ALLELES; BRAIN-DERIVED NEUROTROPHIC FACTOR; DEPRESSIVE DISORDER, MAJOR; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HAPLOTYPES; HUMANS; MALE; MIDDLE AGED; POLAND; POLYMORPHISM, SINGLE NUCLEOTIDE; RECURRENCE; RISK FACTORS;

EID: 79955811339     PISSN: 08958696     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12031-010-9478-y     Document Type: Article

References (37)

1. Anisman H, Merali Z, Hayley S (2008) Neurotransmitter, peptide and cytokine processes in relation to depressive disorder: comorbidity between depression and neurodegenerative disorders. Prog Neurobiol 85(1):1-74
2. Aydemir O, Deveci A, Taneli F (2005) The effect of chronic antidepressant treatment on serum brain-derived neurotrophic factor levels in depressed patients: a preliminary study. Prog Neuropsychopharmacol Biol Psychiatry 29(2):261-265 (Pubitemid 40202912)
3. Chao MV, Rajagopal R, Lee FS (2006) Neurotrophin signalling in health and disease. Clin Sci (Lond) 110(2):167-173 (Pubitemid 43241478)
4. Chen ZY, Patel PD, Sant G, Meng CX, Teng KK, Hempstead BL, Lee FS (2004) Variant brain-derived neurotrophic factor (BDNF) (Met66) alters the intracellular trafficking and activity-dependent secretion of wild-type BDNF in neurosecretory cells and cortical neurons. J Neurosci 24(18):4401-4411 (Pubitemid 38608151)
5. Craddock N, Forty L (2006) Genetics of affective (mood) disorders. Eur J Hum Genet 14(6):660-668 (Pubitemid 43797263)
6. Dell'osso L, Carmassi C, Del Debbio A et al (2009) Brain-derived neurotrophic factor plasma levels in patients suffering from posttraumatic stress disorder. Prog Neuropsychopharmacol Biol Psychiatry 33(5):899-902
7. Duman RS, Monteggia LM (2006) A neurotrophic model for stress-related mood disorders. Biol Psychiatry 59(12):1116-1127
8. Dwivedi Y, Rizavi HS, Conley RR, Roberts RC, Tamminga CA, Pandey GN (2003) Altered gene expression of brain-derived neurotrophic factor and receptor tyrosine kinase B in postmortem brain of suicide subjects. Arch Gen Psychiatry 60(8):804-815 (Pubitemid 36960912)
9. Egan MF, Kojima M, Callicott JH et al (2003) The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function. Cell 112(2):257-269 (Pubitemid 36144114)
10. Frodl T, Schüle C, Schmitt G, et al (2007) Association of the brain-derived neurotrophic factor Val66Met polymorphism with reduced hippocampal volumes in major depression. Arch Gen Psychiatry 64(4):410-416 (Pubitemid 46556460)
11. Ghaemi SN, Ko JY, Goodwin FK (2001) The bipolar spectrum and the antidepressant view of the world. J Psychiatr Pract 7:287-297
12. Gratacòs M, González JR, Mercader JM, de Cid R, Urretavizcaya M, Estivill X (2007) Brain-derived neurotrophic factor Val66Met and psychiatric disorders: meta-analysis of case-control studies confirm association to substance-related disorders, eating disorders, and schizophrenia. Biol Psychiatry 61(7):911-922 (Pubitemid 46420580)
13. Hilt LM, Sander LC, Nolen-Hoeksema S, Simen AA (2007) The BDNF Val66Met polymorphism predicts rumination and depression differently in young adolescent girls and their mothers. Neurosci Lett 429(1):12-16 (Pubitemid 350116345)
14. Hirschfeld RMA, Williams JBW, Spitzer RL, Calabrese JR, Flynn L, Keck PE, Lewis L et al (2000) Development and validation of a screening instrument for bipolar spectrum disorder: the mood disorder questionnaire. Am J Psychiatry 157:1873-1874
15. Hong CJ, Huo SJ, Yen FC, Tung CL, Pan GM, Tsai SJ (2003) Association study of a brain-derived neurotrophic-factor genetic polymorphism and mood disorders, age of onset and suicidal behavior. Neuropsychobiology 48(4):186-189
16. Hovanesian S, Isakov I, Cervellione KL (2009) Defensemechanisms and suicide risk in major depression. Arch Suicide Res 13(1):74-86
17. Jiang X, Xu K, Hoberman J, Tian F et al (2005) BDNF variation and mood disorders: a novel functional promoter polymorphism and Val66Met are associated with anxiety but have opposing effects. Neuropsychopharmacology 30(7):1353-1361 (Pubitemid 40848089)
18. Lang UE, Hellweg R, Kalus P et al (2005) Association of a functional BDNF polymorphism and anxiety-related personality traits. Psychopharmacology (Berl) 180(1):95-99 (Pubitemid 40897075)
19. Levinson DF (2006) The genetics of depression: a review. Biol Psychiatry 60(2):84-92
20. Lopez-Leon S, Janssens AC, González-Zuloeta Ladd AM, Del-Favero J, Claes SJ, Oostra BA, van Duijn CM (2008) Meta-analyses of genetic studies on major depressive disorder. Mol Psychiatry 13 (8):772-785 (Pubitemid 352032108)
21. Maes M, Yirmyia R, Noraberg J et al (2009) The inflammatory & neurodegenerative (I&ND) hypothesis of depression: leads for future research and new drug developments in depression. Metab Brain Dis 24(1):27-53
22. McEwen B (2002) Estrogen actions throughout the brain. Recent Prog Horm Res 57:357-384
23. Nestler EJ, Barrot M, DiLeone RJ, Eisch AJ, Gold SJ, Monteggia LM (2002) Neurobiology of depression. Neuron 34(1):13-25 (Pubitemid 34270695)
24. Neuman RJ, Geller B, Rice JP, Todd RD (1997) Increased prevalence and earlier onset of mood disorders among relatives of prepubertal vs adult probands. J Am Acad Child Adolesc Psychiatry 36:466-473 (Pubitemid 27149183)
25. Oswald P, Del-Favero J, Massat I, Souery D, Claes S, Van Broeckhoven C, Mendlewicz J (2005) No implication of brain-derived neurotrophic factor (BDNF) gene in unipolar affective disorder: evidence from Belgian first and replication patient-control studies. Eur Neuropsychopharmacol 15(5):491-495 (Pubitemid 41219618)
26. Pencea V, Bingaman KD, Wiegand SJ, Luskin MB (2001) Infusion of brain-derived neurotrophic factor into the lateral ventricle of the adult rat leads to new neurons in the parenchyma of the striatum, septum, thalamus, and hypothalamus. J Neurosci 21(17):6706-6717 (Pubitemid 32781115)
27. Ribeiro L, Busnello JV, Cantor RM, Whelan F, Whittaker P, Deloukas P, Wong ML, Licinio J (2007) The brain-derived neurotrophic factor rs6265 (Val66Met) polymorphism and depression in Mexican-Americans. NeuroReport 18(12):1291-1293 (Pubitemid 47075599)
28. Schumacher J, Jamra RA, Becker T et al (2005) Evidence for a relationship between genetic variants at the brain-derived neurotrophic factor (BDNF) locus and major depression. Biol Psychiatry 58(4):307-314 (Pubitemid 41133624)
29. Shalev I, Lerer E, Israel S et al (2009) BDNF Val66Met polymorphism is associated with HPA axis reactivity to psychological stress characterized by genotype and gender interactions. Psychoneuroendocrinology 34(3):382-388
30. Shirayama Y, Chen AC, Nakagawa S, Russell DS, Duman RS (2002) Brain-derived neurotrophic factor produces antidepressant effects in behavioral models of depression. J Neurosci 22 (8):3251-3261 (Pubitemid 35379212)
31. Sohrabji F, Lewis DK (2006) Estrogen-BDNF interactions: implications for neurodegenerative diseases. Front Neuroendocrinol 27 (4):404-414 (Pubitemid 44738016)
32. Strauss J, Barr CL, George CJ, King N, Shaikh S, Devlin B, Kovacs M, Kennedy JL (2004) Association study of brain-derived neurotrophic factor in adults with a history of childhood onset mood disorder. Am J Med Genet B Neuropsychiatr Genet 131B (1):16-19 (Pubitemid 39458432)
33. Strauss J, Barr CL, George CJ et al (2005) Brain-derived neurotrophic factor variants are associated with childhood-onset mood disorder: confirmation in a Hungarian sample. Mol Psychiatry 10 (9):861-867 (Pubitemid 43080120)
34. Taylor WD, Züchner S, McQuoid DR, Steffens DC, Speer MC, Krishnan KR (2007) Allelic differences in the brain-derived neurotrophic factor Val66Met polymorphism in late-life depression. Am J Geriatr Psychiatry 15(10):850-857
35. Tsankova NM, Berton O, Renthal W, Kumar A, Neve RL, Nestler EJ (2006) Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action. Nat Neurosci 9 (4):519-525
36. Verhagen M, van der Meij A, van Deurzen PA, Janzing JG, Arias-Vásquez A, Buitelaar JK, Franke B (2010) Meta-analysis of the BDNF Val66Met polymorphism in major depressive disorder: effects of gender and ethnicity. Mol Psychiatry, 15(3):260-271
37. Zhang H, Ozbay F, Lappalainen J et al (2006) Brain derived neurotrophic factor (BDNF) gene variants and Alzheimer's disease, affective disorders, posttraumatic stress disorder, schizophrenia, and substance dependence. Am J Med Genet B Neuropsychiatr Genet 141B(4):387-393 (Pubitemid 43872891)