CEACAM1 on activated NK cells inhibits NKG2D-mediated cytolytic function and signaling

European Journal of Immunology

Volumn 43, Issue 9, 2013, Pages 2473-2483

  Hosomi, Shuhei ^a   Chen, Zhangguo ^a,b   Baker, Kristi ^a   Chen, Lanfen ^a   Huang, Yu Hwa ^a   Olszak, Torsten ^a   Zeissig, Sebastian ^a   Wang, Jing H ^b   Mandelboim, Ofer ^c   Beauchemin, Nicole ^d   Lanier, Lewis L ^e   Blumberg, Richard S ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b UNIVERSITY OF COLORADO   (United States)

^c HEBREW UNIVERSITY   (Israel)

^d MCGILL UNIVERSITY   (Canada)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

CEACAM1; Cytolysis; Interleukin 2; NK cell; NKG2D

Indexed keywords

CARCINOEMBRYONIC ANTIGEN RELATED CELL ADHESION MOLECULE 1; GUANINE NUCLEOTIDE EXCHANGE FACTOR; INTERLEUKIN 2; NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 1; NATURAL KILLER CELL RECEPTOR NKG2D; PROTEIN TYROSINE PHOSPHATASE SHP 1;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOLYSIS; CYTOTOXICITY; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; LYMPHOCYTE ACTIVATION; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; TUMOR CELL; TUMOR IMMUNITY;

CEACAM1; CYTOLYSIS; INTERLEUKIN-2; NK CELL; NKG2D;

ANIMALS; APOPTOSIS; CARCINOEMBRYONIC ANTIGEN; CELL LINE, TUMOR; HUMANS; INTERLEUKIN-2; KILLER CELLS, NATURAL; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NK CELL LECTIN-LIKE RECEPTOR SUBFAMILY K; PHOSPHORYLATION; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 6; PROTO-ONCOGENE PROTEINS C-VAV; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

EID: 84883518294     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201242676     Document Type: Article

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