The activating NKG2D receptor assembles in the membrane with two signaling dimers into a hexameric structure

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 21, 2005, Pages 7641-7646

  Garrity, David ^a,b   Call, Matthew E ^a,b   Feng, Jianwen ^a,b   Wucherpfennig, Kai W ^a,b  

^a DANA FARBER CANCER INSTITUTE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Membrane biochemistry; Natural killer cells; Stoichiometry

Indexed keywords

ARGININE; DEATH ASSOCIATED PROTEIN KINASE; DIMER; NATURAL KILLER CELL RECEPTOR NKG2D; T LYMPHOCYTE RECEPTOR;

ARTICLE; DIMERIZATION; HUMAN; INNATE IMMUNITY; LIGAND BINDING; MUTATION; NATURAL KILLER CELL; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; SENSITIVITY ANALYSIS; SIGNAL TRANSDUCTION; STOICHIOMETRY; T LYMPHOCYTE SUBPOPULATION;

CELL MEMBRANE; DIMERIZATION; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HUMANS; KILLER CELLS, NATURAL; LIGANDS; MEMBRANE PROTEINS; MICROSOMES; MODELS, MOLECULAR; MUTATION; PHOSPHORYLATION; RECEPTORS, IMMUNOLOGIC; SIGNAL TRANSDUCTION;

EID: 19644365065     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0502439102     Document Type: Article

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