Carcinoembryonic antigen-related cell adhesion molecule 1 inhibits proximal TCR signaling by targeting ZAP-70

Journal of Immunology

Volumn 180, Issue 9, 2008, Pages 6085-6093

  Chen, Zhangguo ^a   Chen, Lanfen ^a   Qiao, Shuo Wang ^a   Nagaishi, Takashi ^a   Blumberg, Richard S ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOEMBRYONIC ANTIGEN RELATED CELL ADHESION MOLECULE 1; CD3 ANTIGEN; PROTEIN KINASE LCK; PROTEIN KINASE ZAP 70; PROTEIN TYROSINE PHOSPHATASE SHP 1; T LYMPHOCYTE RECEPTOR; CD66 ANTIGENS; CELL ADHESION MOLECULE; IMMUNOGLOBULIN F(AB) FRAGMENT; ISOPROTEIN; LEUKOCYTE ANTIGEN; LYMPHOCYTE ANTIGEN RECEPTOR; PTPN6 PROTEIN, HUMAN; ZAP70 PROTEIN, HUMAN;

ANTIGEN BINDING; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; CYTOTOXICITY; EXOCYTOSIS; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; T LYMPHOCYTE ACTIVATION; BINDING SITE; DRUG EFFECT; IMMUNOLOGY; LEUKEMIA CELL LINE; LYMPHOCYTE ACTIVATION; METABOLISM; PHOSPHORYLATION; PROTEIN BINDING; SIGNAL TRANSDUCTION;

AMINO ACID MOTIFS; ANTIGENS, CD; ANTIGENS, CD3; BINDING SITES; CELL ADHESION MOLECULES; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; JURKAT CELLS; LYMPHOCYTE ACTIVATION; LYMPHOCYTE SPECIFIC PROTEIN TYROSINE KINASE P56(LCK); PHOSPHORYLATION; PROTEIN BINDING; PROTEIN ISOFORMS; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 6; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; ZAP-70 PROTEIN-TYROSINE KINASE;

EID: 44449083973     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.180.9.6085     Document Type: Article

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