-
1
-
-
67649794833
-
Intramembrane Proteolysis by Signal Peptide Peptidases: A comparative discussion of GXGD-type aspartyl proteases
-
Fluhrer, R., Steiner, H., and Haass, C. (2009) Intramembrane Proteolysis by Signal Peptide Peptidases: A comparative discussion of GXGD-type aspartyl proteases. J. Biol. Chem. 284, 13975-13979
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 13975-13979
-
-
Fluhrer, R.1
Steiner, H.2
Haass, C.3
-
2
-
-
67649827390
-
Intramembrane-cleaving proteases
-
Wolfe, M.S. (2009) Intramembrane-cleaving proteases. J. Biol. Chem. 284, 13969-13973
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 13969-13973
-
-
Wolfe, M.S.1
-
3
-
-
4143084775
-
Intramembrane proteolysis: Theme and variations
-
Wolfe, M.S. and Kopan, R. (2004) Intramembrane proteolysis: Theme and variations. Science 305, 1119-1123
-
(2004)
Science
, vol.305
, pp. 1119-1123
-
-
Wolfe, M.S.1
Kopan, R.2
-
4
-
-
15644375065
-
Promiscuous liberation of MHC-class I-binding peptides from the C termini of membrane and soluble proteins in the secretory pathway
-
Snyder, H.L., Bacik, I., Yewdell, J.W., Behrens, T.W., and Bennink, J.R. (1998) Promiscuous liberation of MHC-class I-binding peptides from the C termini of membrane and soluble proteins in the secretory pathway. Eur. J. Immunol. 28, 1339-1346
-
(1998)
Eur. J. Immunol.
, vol.28
, pp. 1339-1346
-
-
Snyder, H.L.1
Bacik, I.2
Yewdell, J.W.3
Behrens, T.W.4
Bennink, J.R.5
-
5
-
-
0034913229
-
ER aminopeptidases generate a unique pool of peptides for MHC class I molecules
-
Serwold, T., Gaw, S., and Shastri, N. (2001) ER aminopeptidases generate a unique pool of peptides for MHC class I molecules. Nat. Immunol. 2, 644-651
-
(2001)
Nat. Immunol.
, vol.2
, pp. 644-651
-
-
Serwold, T.1
Gaw, S.2
Shastri, N.3
-
6
-
-
0034907526
-
MHC class I molecules can direct proteolytic cleavage of antigenic precursors in the endoplasmic reticulum
-
Brouwenstijn, N., Serwold, T., and Shastri, N. (2001) MHC class I molecules can direct proteolytic cleavage of antigenic precursors in the endoplasmic reticulum. Immunity 15, 95-104
-
(2001)
Immunity
, vol.15
, pp. 95-104
-
-
Brouwenstijn, N.1
Serwold, T.2
Shastri, N.3
-
7
-
-
0035839492
-
A role for a novel luminal endoplasmic reticulum aminopeptidase in final trimming of 26S proteasomegenerated major histocompatability complex class I antigenic peptides
-
Komlosh, A., Momburg, F., Weinschenk, T., Emmerich, N., Schild, H., Nadav, E., Shaked, I., and Reiss, Y. (2001) A role for a novel luminal endoplasmic reticulum aminopeptidase in final trimming of 26S proteasomegenerated major histocompatability complex class I antigenic peptides. J. Biol. Chem. 276, 30050-30056
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 30050-30056
-
-
Komlosh, A.1
Momburg, F.2
Weinschenk, T.3
Emmerich, N.4
Schild, H.5
Nadav, E.6
Shaked, I.7
Reiss, Y.8
-
8
-
-
0037015624
-
ERAAP customizes peptides for MHC class I molecules in the endoplasmic reticulum
-
Serwold, T., Gonzalez, F., Kim, J., Jacob, R., and Shastri, N. (2002) ERAAP customizes peptides for MHC class I molecules in the endoplasmic reticulum. Nature 419, 480-483
-
(2002)
Nature
, vol.419
, pp. 480-483
-
-
Serwold, T.1
Gonzalez, F.2
Kim, J.3
Jacob, R.4
Shastri, N.5
-
9
-
-
0042357061
-
Human leukocyte-derived arginine aminopeptidase The third member of the oxytocinase subfamily of aminopeptidases
-
Tanioka, T., Hattori, A., Masuda, S., Nomura, Y., Nakayama, H., Mizutani, S., and Tsujimoto, M. (2003) Human leukocyte-derived arginine aminopeptidase. The third member of the oxytocinase subfamily of aminopeptidases. J. Biol. Chem. 278, 32275-32283
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 32275-32283
-
-
Tanioka, T.1
Hattori, A.2
Masuda, S.3
Nomura, Y.4
Nakayama, H.5
Mizutani, S.6
Tsujimoto, M.7
-
10
-
-
0036902105
-
An IFN-gamma-induced aminopeptidase in the ER, ERAP1, trims precursors to MHC class I-presented peptides
-
Saric, T., Chang, S.C., Hattori, A., York, I.A., Markant, S., Rock, K.L., Tsujimoto, M., and Goldberg, A.L. (2002) An IFN-gamma-induced aminopeptidase in the ER, ERAP1, trims precursors to MHC class I-presented peptides. Nat. Immunol. 3, 1169-1176
-
(2002)
Nat. Immunol.
, vol.3
, pp. 1169-1176
-
-
Saric, T.1
Chang, S.C.2
Hattori, A.3
York, I.A.4
Markant, S.5
Rock, K.L.6
Tsujimoto, M.7
Goldberg, A.L.8
-
11
-
-
0033667227
-
Characterization of recombinant human adipocyte-derived leucine aminopeptidase expressed in Chinese hamster ovary cells
-
Hattori, A., Kitatani, K., Matsumoto, H., Miyazawa, S., Rogi, T., Tsuruoka, N., Mizutani, S., Natori, Y., and Tsujimoto, M. (2000) Characterization of recombinant human adipocyte-derived leucine aminopeptidase expressed in Chinese hamster ovary cells. J. Biochem. 128, 755-762
-
(2000)
J. Biochem.
, vol.128
, pp. 755-762
-
-
Hattori, A.1
Kitatani, K.2
Matsumoto, H.3
Miyazawa, S.4
Rogi, T.5
Tsuruoka, N.6
Mizutani, S.7
Natori, Y.8
Tsujimoto, M.9
-
12
-
-
0030049295
-
Human placental leucine aminopeptidase/oxytocinase A new member of type II membrane-spanning zinc metallopeptidase family
-
Rogi, T., Tsujimoto, M., Nakazato, H., Mizutani, S., and Tomoda, Y. (1996) Human placental leucine aminopeptidase/oxytocinase. A new member of type II membrane-spanning zinc metallopeptidase family. J. Biol. Chem. 271, 56-61
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 56-61
-
-
Rogi, T.1
Tsujimoto, M.2
Nakazato, H.3
Mizutani, S.4
Tomoda, Y.5
-
13
-
-
0030063398
-
Characterization of the insulin-regulated membrane aminopeptidase in 3T3-L1 adipocytes
-
Ross, S.A., Scott, H.M., Morris, N.J., Leung, W.Y., Mao, F., Lienhard, G.E., and Keller, S.R. (1996) Characterization of the insulin-regulated membrane aminopeptidase in 3T3-L1 adipocytes. J. Biol. Chem. 271, 3328-3332
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 3328-3332
-
-
Ross, S.A.1
Scott, H.M.2
Morris, N.J.3
Leung, W.Y.4
Mao, F.5
Lienhard, G.E.6
Keller, S.R.7
-
14
-
-
0028817838
-
Cloning and characterization of a novel insulin-regulated membrane aminopeptidase from Glut4 vesicles
-
Keller, S.R., Scott, H.M., Mastick, C.C., Aebersold, R., and Lienhard, G.E. (1995) Cloning and characterization of a novel insulin-regulated membrane aminopeptidase from Glut4 vesicles. J. Biol. Chem. 270, 23612-23618
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 23612-23618
-
-
Keller, S.R.1
Scott, H.M.2
Mastick, C.C.3
Aebersold, R.4
Lienhard, G.E.5
-
15
-
-
16644366208
-
Alzheimer's, angiotensin IV and an aminopeptidase
-
Albiston, A.L., Fernando, R., Ye, S., Peck, G.R., and Chai, S.Y. (2004) Alzheimer's, angiotensin IV and an aminopeptidase. Biol. Pharm. Bull. 27, 765-767
-
(2004)
Biol. Pharm. Bull.
, vol.27
, pp. 765-767
-
-
Albiston, A.L.1
Fernando, R.2
Ye, S.3
Peck, G.R.4
Chai, S.Y.5
-
16
-
-
0035966085
-
Evidence that the angiotensin IV (AT(4)) receptor is the enzyme insulin-regulated aminopeptidase
-
Albiston, A.L., McDowall, S.G., Matsacos, D., Sim, P., Clune, E., Mustafa, T., Lee, J., Mendelsohn, F.A., Simpson, R.J., Connolly, L.M., and Chai, S.Y. (2001) Evidence that the angiotensin IV (AT(4)) receptor is the enzyme insulin-regulated aminopeptidase. J. Biol. Chem. 276, 48623-48626
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 48623-48626
-
-
Albiston, A.L.1
McDowall, S.G.2
Matsacos, D.3
Sim, P.4
Clune, E.5
Mustafa, T.6
Lee, J.7
Mendelsohn, F.A.8
Simpson, R.J.9
Connolly, L.M.10
Chai, S.Y.11
-
17
-
-
0034850467
-
Expression of placental leucine aminopeptidase/oxytocinase in neuronal cells and its action on neuronal peptides
-
Matsumoto, H., Nagasaka, T., Hattori, A., Rogi, T., Tsuruoka, N., Mizutani, S., and Tsujimoto, M. (2001) Expression of placental leucine aminopeptidase/oxytocinase in neuronal cells and its action on neuronal peptides. Eur. J. Biochem. 268, 3259-3266
-
(2001)
Eur. J. Biochem.
, vol.268
, pp. 3259-3266
-
-
Matsumoto, H.1
Nagasaka, T.2
Hattori, A.3
Rogi, T.4
Tsuruoka, N.5
Mizutani, S.6
Tsujimoto, M.7
-
18
-
-
0034599050
-
Placental leucine aminopeptidase/oxytocinase in maternal serum and placenta during normal pregnancy
-
Yamahara, N., Nomura, S., Suzuki, T., Itakura, A., Ito, M., Okamoto, T., Tsujimoto, M., Nakazato, H., and Mizutani, S. (2000) Placental leucine aminopeptidase/oxytocinase in maternal serum and placenta during normal pregnancy. Life Sci. 66, 1401-1410
-
(2000)
Life Sci.
, vol.66
, pp. 1401-1410
-
-
Yamahara, N.1
Nomura, S.2
Suzuki, T.3
Itakura, A.4
Ito, M.5
Okamoto, T.6
Tsujimoto, M.7
Nakazato, H.8
Mizutani, S.9
-
19
-
-
0033958063
-
Characterization of a recombinant soluble form of human placental leucine aminopeptidase/oxytocinase expressed in Chinese hamster ovary cells
-
Matsumoto, H., Rogi, T., Yamashiro, K., Kodama, S., Tsuruoka, N., Hattori, A., Takio, K., Mizutani, S., and Tsujimoto, M. (2000) Characterization of a recombinant soluble form of human placental leucine aminopeptidase/ oxytocinase expressed in Chinese hamster ovary cells. Eur. J. Biochem. 267, 46-52
-
(2000)
Eur. J. Biochem.
, vol.267
, pp. 46-52
-
-
Matsumoto, H.1
Rogi, T.2
Yamashiro, K.3
Kodama, S.4
Tsuruoka, N.5
Hattori, A.6
Takio, K.7
Mizutani, S.8
Tsujimoto, M.9
-
20
-
-
67650465638
-
IRAP identifies an endosomal compartment required for MHC class I cross-presentation
-
Saveanu, L., Carroll, O., Weimershaus, M., Guermonprez, P., Firat, E., Lindo, V., Greer, F., Davoust, J., Kratzer, R., Keller, S.R., Niedermann, G., and van Endert, P. (2009) IRAP identifies an endosomal compartment required for MHC class I cross-presentation. Science 325, 213-217
-
(2009)
Science
, vol.325
, pp. 213-217
-
-
Saveanu, L.1
Carroll, O.2
Weimershaus, M.3
Guermonprez, P.4
Firat, E.5
Lindo, V.6
Greer, F.7
Davoust, J.8
Kratzer, R.9
Keller, S.R.10
Niedermann, G.11
Van Endert, P.12
-
21
-
-
0033056047
-
Molecular cloning of adipocytederived leucine aminopeptidase highly related to placental leucine aminopeptidase/oxytocinase
-
Hattori, A., Matsumoto, H., Mizutani, S., and Tsujimoto, M. (1999) Molecular cloning of adipocytederived leucine aminopeptidase highly related to placental leucine aminopeptidase/oxytocinase. J. Biochem. 125, 931-938
-
(1999)
J. Biochem.
, vol.125
, pp. 931-938
-
-
Hattori, A.1
Matsumoto, H.2
Mizutani, S.3
Tsujimoto, M.4
-
22
-
-
0036565887
-
A mouse orthologue of puromycin-insensitive leucyl-specific aminopeptidase is expressed in endothelial cells and plays an important role in angiogenesis
-
Miyashita, H., Yamazaki, T., Akada, T., Niizeki, O., Ogawa, M., Nishikawa, S., and Sato, Y. (2002) A mouse orthologue of puromycin-insensitive leucyl-specific aminopeptidase is expressed in endothelial cells and plays an important role in angiogenesis. Blood 99, 3241-3249
-
(2002)
Blood
, vol.99
, pp. 3241-3249
-
-
Miyashita, H.1
Yamazaki, T.2
Akada, T.3
Niizeki, O.4
Ogawa, M.5
Nishikawa, S.6
Sato, Y.7
-
23
-
-
0036679366
-
Identification of ARTS-1 as a novel TNFR1-binding protein that promotes TNFR1 ectodomain shedding
-
Cui, X., Hawari, F., Alsaaty, S., Lawrence, M., Combs, C.A., Geng, W., Rouhani, F.N., Miskinis, D., and Levine, S.J. (2002) Identification of ARTS-1 as a novel TNFR1-binding protein that promotes TNFR1 ectodomain shedding. J. Clin. Invest. 110, 515-526
-
(2002)
J. Clin. Invest.
, vol.110
, pp. 515-526
-
-
Cui, X.1
Hawari, F.2
Alsaaty, S.3
Lawrence, M.4
Combs, C.A.5
Geng, W.6
Rouhani, F.N.7
Miskinis, D.8
Levine, S.J.9
-
24
-
-
0034873358
-
Genomic organization of the human adipocyte-derived leucine aminopeptidase gene and its relationship to the placental leucine aminopeptidase/oxytocinase gene
-
Hattori, A., Matsumoto, K., Mizutani, S., and Tsujimoto, M. (2001) Genomic organization of the human adipocyte-derived leucine aminopeptidase gene and its relationship to the placental leucine aminopeptidase/oxytocinase gene. J. Biochem. 130, 235-241
-
(2001)
J. Biochem.
, vol.130
, pp. 235-241
-
-
Hattori, A.1
Matsumoto, K.2
Mizutani, S.3
Tsujimoto, M.4
-
25
-
-
14044259920
-
Regulation of the human leukocyte-derived arginine aminopeptidase/ endoplasmic reticulum-aminopeptidase 2 gene by interferon-gamma
-
Tanioka, T., Hattori, A., Mizutani, S., and Tsujimoto, M. (2005) Regulation of the human leukocyte-derived arginine aminopeptidase/endoplasmic reticulum-aminopeptidase 2 gene by interferon-gamma. FEBS J. 272, 916-928
-
(2005)
FEBS J.
, vol.272
, pp. 916-928
-
-
Tanioka, T.1
Hattori, A.2
Mizutani, S.3
Tsujimoto, M.4
-
26
-
-
22744438096
-
The oxytocinase subfamily of M1 aminopeptidases
-
Tsujimoto, M. and Hattori, A. (2005) The oxytocinase subfamily of M1 aminopeptidases. Biochim. Biophys. Acta 1751, 9-18
-
(2005)
Biochim. Biophys. Acta
, vol.1751
, pp. 9-18
-
-
Tsujimoto, M.1
Hattori, A.2
-
27
-
-
4944266006
-
Puromycin-insensitive leucyl-specific aminopeptidase (PILSAP) binds and catalyzes PDK1, allowing VEGF-stimulated activation of S6K for endothelial cell proliferation and angiogenesis
-
Yamazaki, T., Akada, T., Niizeki, O., Suzuki, T., Miyashita, H., and Sato, Y. (2004) Puromycin-insensitive leucyl-specific aminopeptidase (PILSAP) binds and catalyzes PDK1, allowing VEGF-stimulated activation of S6K for endothelial cell proliferation and angiogenesis. Blood 104, 2345-2352
-
(2004)
Blood
, vol.104
, pp. 2345-2352
-
-
Yamazaki, T.1
Akada, T.2
Niizeki, O.3
Suzuki, T.4
Miyashita, H.5
Sato, Y.6
-
28
-
-
0036837068
-
Puromycin insensitive leucyl-specific aminopeptidase (PILSAP) is involved in the activation of endothelial integrins
-
Akada, T., Yamazaki, T., Miyashita, H., Niizeki, O., Abe, M., Sato, A., Satomi, S., and Sato, Y. (2002) Puromycin insensitive leucyl-specific aminopeptidase (PILSAP) is involved in the activation of endothelial integrins. J. Cell Physiol. 193, 253-262
-
(2002)
J. Cell Physiol.
, vol.193
, pp. 253-262
-
-
Akada, T.1
Yamazaki, T.2
Miyashita, H.3
Niizeki, O.4
Abe, M.5
Sato, A.6
Satomi, S.7
Sato, Y.8
-
29
-
-
16644386079
-
Role of aminopeptidase in angiogenesis
-
Sato, Y. (2004) Role of aminopeptidase in angiogenesis. Biol. Pharm. Bull. 27, 772-776
-
(2004)
Biol. Pharm. Bull.
, vol.27
, pp. 772-776
-
-
Sato, Y.1
-
30
-
-
56349128364
-
The internal sequence of the peptide-substrate determines its N-terminus trimming by ERAP1
-
Evnouchidou, I., Momburg, F., Papakyriakou, A., Chroni, A., Leondiadis, L., Chang, S.C., Goldberg, A.L., and Stratikos, E. (2008) The internal sequence of the peptide-substrate determines its N-terminus trimming by ERAP1. PLoS One 3, e3658
-
(2008)
PLoS One
, vol.3
-
-
Evnouchidou, I.1
Momburg, F.2
Papakyriakou, A.3
Chroni, A.4
Leondiadis, L.5
Chang, S.C.6
Goldberg, A.L.7
Stratikos, E.8
-
31
-
-
0034696532
-
Histidine 450 plays a critical role in catalysis and, with Ca2+, contributes to the substrate specificity of aminopeptidase A
-
Iturrioz, X., Vazeux, G., Celerier, J., Corvol, P., and Llorens-Cortes, C. (2000) Histidine 450 plays a critical role in catalysis and, with Ca2+, contributes to the substrate specificity of aminopeptidase A. Biochemistry 39, 3061-3068
-
(2000)
Biochemistry
, vol.39
, pp. 3061-3068
-
-
Iturrioz, X.1
Vazeux, G.2
Celerier, J.3
Corvol, P.4
Llorens-Cortes, C.5
-
32
-
-
56049109055
-
Glutamine-181 is crucial in the enzymatic activity and substrate specificity of human endoplasmic-reticulum aminopeptidase-1
-
Goto, Y., Tanji, H., Hattori, A., and Tsujimoto, M. (2008) Glutamine-181 is crucial in the enzymatic activity and substrate specificity of human endoplasmic-reticulum aminopeptidase-1. Biochem. J. 416, 109-116
-
(2008)
Biochem. J.
, vol.416
, pp. 109-116
-
-
Goto, Y.1
Tanji, H.2
Hattori, A.3
Tsujimoto, M.4
-
33
-
-
33644908217
-
Reduced activity of the hypertension-associated Lys528Arg mutant of human adipocyte-derived leucine aminopeptidase (A-LAP)/ER-aminopeptidase-1
-
Goto, Y., Hattori, A., Ishii, Y., and Tsujimoto, M. (2006) Reduced activity of the hypertension-associated Lys528Arg mutant of human adipocyte-derived leucine aminopeptidase (A-LAP)/ER-aminopeptidase-1. FEBS Lett. 580, 1833-1838
-
(2006)
FEBS Lett.
, vol.580
, pp. 1833-1838
-
-
Goto, Y.1
Hattori, A.2
Ishii, Y.3
Tsujimoto, M.4
-
34
-
-
84865421949
-
A common single nucleotide polymorphism in endoplasmic reticulum aminopeptidase 2 induces a specificity switch that leads to altered antigen processing
-
Evnouchidou, I., Birtley, J., Seregin, S., Papakyriakou, A., Zervoudi, E., Samiotaki, M., Panayotou, G., Giastas, P., Petrakis, O., Georgiadis, D., Amalfitano, A., Saridakis, E., Mavridis, I.M., and Stratikos, E. (2012) A common single nucleotide polymorphism in endoplasmic reticulum aminopeptidase 2 induces a specificity switch that leads to altered antigen processing. J. Immunol. 189, 2383-2392
-
(2012)
J. Immunol.
, vol.189
, pp. 2383-2392
-
-
Evnouchidou, I.1
Birtley, J.2
Seregin, S.3
Papakyriakou, A.4
Zervoudi, E.5
Samiotaki, M.6
Panayotou, G.7
Giastas, P.8
Petrakis, O.9
Georgiadis, D.10
Amalfitano, A.11
Saridakis, E.12
Mavridis, I.M.13
Stratikos, E.14
-
35
-
-
0036884090
-
The ER aminopeptidase ERAP1 enhances or limits antigen presentation by trimming epitopes to 8-9 residues
-
York, I.A., Chang, S.C., Saric, T., Keys, J.A., Favreau, J.M., Goldberg, A.L., and Rock, K.L. (2002) The ER aminopeptidase ERAP1 enhances or limits antigen presentation by trimming epitopes to 8-9 residues. Nat. Immunol. 3, 1177-1184
-
(2002)
Nat. Immunol.
, vol.3
, pp. 1177-1184
-
-
York, I.A.1
Chang, S.C.2
Saric, T.3
Keys, J.A.4
Favreau, J.M.5
Goldberg, A.L.6
Rock, K.L.7
-
36
-
-
28044456942
-
The ER aminopeptidase, ERAP1, trims precursors to lengths of MHC class I peptides by a ''molecular ruler'' mechanism
-
Chang, S.C., Momburg, F., Bhutani, N., and Goldberg, A.L. (2005) The ER aminopeptidase, ERAP1, trims precursors to lengths of MHC class I peptides by a ''molecular ruler'' mechanism. Proc. Natl Acad. Sci. U.S.A. 102, 17107-17112
-
(2005)
Proc. Natl Acad. Sci. U.S.A.
, vol.102
, pp. 17107-17112
-
-
Chang, S.C.1
Momburg, F.2
Bhutani, N.3
Goldberg, A.L.4
-
37
-
-
79955638487
-
Structural basis for antigenic peptide precursor processing by the endoplasmic reticulum aminopeptidase ERAP1
-
Nguyen, T.T., Chang, S.C., Evnouchidou, I., York, I.A., Zikos, C., Rock, K.L., Goldberg, A.L., Stratikos, E., and Stern, L.J. (2011) Structural basis for antigenic peptide precursor processing by the endoplasmic reticulum aminopeptidase ERAP1. Nat. Struct. Mol. Biol. 18, 604-613
-
(2011)
Nat. Struct. Mol. Biol.
, vol.18
, pp. 604-613
-
-
Nguyen, T.T.1
Chang, S.C.2
Evnouchidou, I.3
York, I.A.4
Zikos, C.5
Rock, K.L.6
Goldberg, A.L.7
Stratikos, E.8
Stern, L.J.9
-
38
-
-
79956348710
-
Crystal structures of the endoplasmic reticulum aminopeptidase-1 (ERAP1) reveal the molecular basis for N-terminal peptide trimming
-
Kochan, G., Krojer, T., Harvey, D., Fischer, R., Chen, L., Vollmar, M., von Delft, F., Kavanagh, K.L., Brown, M.A., Bowness, P., Wordsworth, P., Kessler, B.M., and Oppermann, U. (2011) Crystal structures of the endoplasmic reticulum aminopeptidase-1 (ERAP1) reveal the molecular basis for N-terminal peptide trimming. Proc. Natl Acad. Sci. U.S.A. 108, 7745-7750
-
(2011)
Proc. Natl Acad. Sci. U.S.A.
, vol.108
, pp. 7745-7750
-
-
Kochan, G.1
Krojer, T.2
Harvey, D.3
Fischer, R.4
Chen, L.5
Vollmar, M.6
Von Delft, F.7
Kavanagh, K.L.8
Brown, M.A.9
Bowness, P.10
Wordsworth, P.11
Kessler, B.M.12
Oppermann, U.13
-
39
-
-
43249098656
-
Structural basis for the unusual specificity of Escherichia coli aminopeptidase N
-
Addlagatta, A., Gay, L., and Matthews, B.W. (2008) Structural basis for the unusual specificity of Escherichia coli aminopeptidase N. Biochemistry 47, 5303-5311
-
(2008)
Biochemistry
, vol.47
, pp. 5303-5311
-
-
Addlagatta, A.1
Gay, L.2
Matthews, B.W.3
-
40
-
-
33845954688
-
Crystal structure of aminopeptidase N (proteobacteria alanyl aminopeptidase) from Escherichia coli and conformational change of methionine 260 involved in substrate recognition
-
Ito, K., Nakajima, Y., Onohara, Y., Takeo, M., Nakashima, K., Matsubara, F., Ito, T., and Yoshimoto, T. (2006) Crystal structure of aminopeptidase N (proteobacteria alanyl aminopeptidase) from Escherichia coli and conformational change of methionine 260 involved in substrate recognition. J. Biol. Chem. 281, 33664-33676
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 33664-33676
-
-
Ito, K.1
Nakajima, Y.2
Onohara, Y.3
Takeo, M.4
Nakashima, K.5
Matsubara, F.6
Ito, T.7
Yoshimoto, T.8
-
41
-
-
62449312343
-
Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase
-
McGowan, S., Porter, C.J., Lowther, J., Stack, C.M., Golding, S.J., Skinner-Adams, T.S., Trenholme, K.R., Teuscher, F., Donnelly, S.M., Grembecka, J., Mucha, A., Kafarski, P., Degori, R., Buckle, A.M., Gardiner, D.L., Whisstock, J.C., and Dalton, J.P. (2009) Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase. Proc. Natl Acad. Sci. U.S.A. 106, 2537-2542
-
(2009)
Proc. Natl Acad. Sci. U.S.A.
, vol.106
, pp. 2537-2542
-
-
McGowan, S.1
Porter, C.J.2
Lowther, J.3
Stack, C.M.4
Golding, S.J.5
Skinner-Adams, T.S.6
Trenholme, K.R.7
Teuscher, F.8
Donnelly, S.M.9
Grembecka, J.10
Mucha, A.11
Kafarski, P.12
Degori, R.13
Buckle, A.M.14
Gardiner, D.L.15
Whisstock, J.C.16
Dalton, J.P.17
-
42
-
-
84856935252
-
Crystal structure of human ER aminopeptidase 2 reveals atomic basis for distinct roles in antigen processing
-
Birtley, J.R., Saridakis, E., Stratikos, E., and Mavridis, I.M. (2012) Crystal structure of human ER aminopeptidase 2 reveals atomic basis for distinct roles in antigen processing. Biochemistry 51, 286-295
-
(2012)
Biochemistry
, vol.51
, pp. 286-295
-
-
Birtley, J.R.1
Saridakis, E.2
Stratikos, E.3
Mavridis, I.M.4
-
43
-
-
14044255662
-
Processing of antigenic peptides by aminopeptidases
-
Hattori, A. and Tsujimoto, M. (2004) Processing of antigenic peptides by aminopeptidases. Biol. Pharm. Bull. 27, 777-780
-
(2004)
Biol. Pharm. Bull.
, vol.27
, pp. 777-780
-
-
Hattori, A.1
Tsujimoto, M.2
-
44
-
-
0036777957
-
The importance of the proteasome and subsequent proteolytic steps in the generation of antigenic peptides
-
Goldberg, A.L., Cascio, P., Saric, T., and Rock, K.L. (2002) The importance of the proteasome and subsequent proteolytic steps in the generation of antigenic peptides. Mol. Immunol. 39, 147-164
-
(2002)
Mol. Immunol.
, vol.39
, pp. 147-164
-
-
Goldberg, A.L.1
Cascio, P.2
Saric, T.3
Rock, K.L.4
-
45
-
-
3242807547
-
Postproteasomal antigen processing for major histocompatibility complex class I presentation
-
Rock, K.L., York, I.A., and Goldberg, A.L. (2004) Postproteasomal antigen processing for major histocompatibility complex class I presentation. Nat. Immunol. 5, 670-677
-
(2004)
Nat. Immunol.
, vol.5
, pp. 670-677
-
-
Rock, K.L.1
York, I.A.2
Goldberg, A.L.3
-
46
-
-
0032563221
-
Interferon-gamma can stimulate post-proteasomal trimming of the N terminus of an antigenic peptide by inducing leucine aminopeptidase
-
Beninga, J., Rock, K.L., and Goldberg, A.L. (1998) Interferon-gamma can stimulate post-proteasomal trimming of the N terminus of an antigenic peptide by inducing leucine aminopeptidase. J. Biol. Chem. 273, 18734-18742
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 18734-18742
-
-
Beninga, J.1
Rock, K.L.2
Goldberg, A.L.3
-
47
-
-
77951294488
-
Analysis of the role of tripeptidyl peptidase II in MHC class I antigen presentation in vivo
-
Kawahara, M., York, I.A., Hearn, A., Farfan, D., and Rock, K.L. (2009) Analysis of the role of tripeptidyl peptidase II in MHC class I antigen presentation in vivo. J. Immunol. 183, 6069-6077
-
(2009)
J. Immunol.
, vol.183
, pp. 6069-6077
-
-
Kawahara, M.1
York, I.A.2
Hearn, A.3
Farfan, D.4
Rock, K.L.5
-
48
-
-
40749125369
-
Puromycin-sensitive aminopeptidase limits MHC class I presentation in dendritic cells but does not affect CD8 T cell responses during viral infections
-
Towne, C.F., York, I.A., Neijssen, J., Karow, M.L., Murphy, A.J., Valenzuela, D.M., Yancopoulos, G.D., Neefjes, J.J., and Rock, K.L. (2008) Puromycin-sensitive aminopeptidase limits MHC class I presentation in dendritic cells but does not affect CD8 T cell responses during viral infections. J. Immunol. 180, 1704-1712
-
(2008)
J. Immunol.
, vol.180
, pp. 1704-1712
-
-
Towne, C.F.1
York, I.A.2
Neijssen, J.3
Karow, M.L.4
Murphy, A.J.5
Valenzuela, D.M.6
Yancopoulos, G.D.7
Neefjes, J.J.8
Rock, K.L.9
-
49
-
-
34249781996
-
Analysis of the role of bleomycin hydrolase in antigen presentation and the generation of CD8 T cell responses
-
Towne, C.F., York, I.A., Watkin, L.B., Lazo, J.S., and Rock, K.L. (2007) Analysis of the role of bleomycin hydrolase in antigen presentation and the generation of CD8 T cell responses. J. Immunol. 178, 6923-6930
-
(2007)
J. Immunol.
, vol.178
, pp. 6923-6930
-
-
Towne, C.F.1
York, I.A.2
Watkin, L.B.3
Lazo, J.S.4
Rock, K.L.5
-
50
-
-
0037341473
-
The cytosolic endopeptidase, thimet oligopeptidase, destroys antigenic peptides and limits the extent of MHC class I antigen presentation
-
York, I.A., Mo, A.X., Lemerise, K., Zeng, W., Shen, Y., Abraham, C.R., Saric, T., Goldberg, A.L., and Rock, K.L. (2003) The cytosolic endopeptidase, thimet oligopeptidase, destroys antigenic peptides and limits the extent of MHC class I antigen presentation. Immunity 18, 429-440
-
(2003)
Immunity
, vol.18
, pp. 429-440
-
-
York, I.A.1
Mo, A.X.2
Lemerise, K.3
Zeng, W.4
Shen, Y.5
Abraham, C.R.6
Saric, T.7
Goldberg, A.L.8
Rock, K.L.9
-
51
-
-
0036080131
-
The transporter associated with antigen processing: Function and implications in human diseases
-
Lankat-Buttgereit, B. and Tampe, R. (2002) The transporter associated with antigen processing: Function and implications in human diseases. Physiol. Rev. 82, 187-204
-
(2002)
Physiol. Rev.
, vol.82
, pp. 187-204
-
-
Lankat-Buttgereit, B.1
Tampe, R.2
-
52
-
-
77955895736
-
ABC proteins in antigen translocation and viral inhibition
-
Parcej, D. and Tampe, R. (2010) ABC proteins in antigen translocation and viral inhibition. Nat. Chem. Biol. 6, 572-580
-
(2010)
Nat. Chem. Biol.
, vol.6
, pp. 572-580
-
-
Parcej, D.1
Tampe, R.2
-
53
-
-
33645089946
-
In vivo role of ERassociated peptidase activity in tailoring peptides for presentation by MHC class Ia and class Ib molecules
-
Yan, J., Parekh, V.V., Mendez-Fernandez, Y., Olivares-Villagomez, D., Dragovic, S., Hill, T., Roopenian, D.C., Joyce, S., and Van Kaer, L. (2006) In vivo role of ERassociated peptidase activity in tailoring peptides for presentation by MHC class Ia and class Ib molecules. J. Exp. Med. 203, 647-659
-
(2006)
J. Exp. Med.
, vol.203
, pp. 647-659
-
-
Yan, J.1
Parekh, V.V.2
Mendez-Fernandez, Y.3
Olivares-Villagomez, D.4
Dragovic, S.5
Hill, T.6
Roopenian, D.C.7
Joyce, S.8
Van Kaer, L.9
-
54
-
-
29244461714
-
The aminopeptidase ERAAP shapes the peptide repertoire displayed by major histocompatibility complex class I molecules
-
Hammer, G.E., Gonzalez, F., Champsaur, M., Cado, D., and Shastri, N. (2006) The aminopeptidase ERAAP shapes the peptide repertoire displayed by major histocompatibility complex class I molecules. Nat. Immunol. 7, 103-112
-
(2006)
Nat. Immunol.
, vol.7
, pp. 103-112
-
-
Hammer, G.E.1
Gonzalez, F.2
Champsaur, M.3
Cado, D.4
Shastri, N.5
-
55
-
-
33745125912
-
Endoplasmic reticulum aminopeptidase 1 (ERAP1) trims MHC class I-presented peptides in vivo and plays an important role in immunodominance
-
York, I.A., Brehm, M.A., Zendzian, S., Towne, C.F., and Rock, K.L. (2006) Endoplasmic reticulum aminopeptidase 1 (ERAP1) trims MHC class I-presented peptides in vivo and plays an important role in immunodominance. Proc. Natl Acad. Sci. U.S.A. 103, 9202-9207
-
(2006)
Proc. Natl Acad. Sci. U.S.A.
, vol.103
, pp. 9202-9207
-
-
York, I.A.1
Brehm, M.A.2
Zendzian, S.3
Towne, C.F.4
Rock, K.L.5
-
56
-
-
33846988640
-
In the absence of aminopeptidase ERAAP, MHC class I molecules present many unstable and highly immunogenic peptides
-
Hammer, G.E., Gonzalez, F., James, E., Nolla, H., and Shastri, N. (2007) In the absence of aminopeptidase ERAAP, MHC class I molecules present many unstable and highly immunogenic peptides. Nat. Immunol. 8, 101-108
-
(2007)
Nat. Immunol.
, vol.8
, pp. 101-108
-
-
Hammer, G.E.1
Gonzalez, F.2
James, E.3
Nolla, H.4
Shastri, N.5
-
57
-
-
79953203538
-
Probing the S1 specificity pocket of the aminopeptidases that generate antigenic peptides
-
Zervoudi, E., Papakyriakou, A., Georgiadou, D., Evnouchidou, I., Gajda, A., Poreba, M., Salvesen, G.S., Drag, M., Hattori, A., Swevers, L., Vourloumis, D., and Stratikos, E. (2011) Probing the S1 specificity pocket of the aminopeptidases that generate antigenic peptides. Biochem. J. 435, 411-420
-
(2011)
Biochem. J.
, vol.435
, pp. 411-420
-
-
Zervoudi, E.1
Papakyriakou, A.2
Georgiadou, D.3
Evnouchidou, I.4
Gajda, A.5
Poreba, M.6
Salvesen, G.S.7
Drag, M.8
Hattori, A.9
Swevers, L.10
Vourloumis, D.11
Stratikos, E.12
-
58
-
-
22144442460
-
Concerted peptide trimming by human ERAP1 and ERAP2 aminopeptidase complexes in the endoplasmic reticulum
-
Saveanu, L., Carroll, O., Lindo, V., Del Val, M., Lopez, D., Lepelletier, Y., Greer, F., Schomburg, L., Fruci, D., Niedermann, G., and van Endert, P.M. (2005) Concerted peptide trimming by human ERAP1 and ERAP2 aminopeptidase complexes in the endoplasmic reticulum. Nat. Immunol. 6, 689-697
-
(2005)
Nat. Immunol.
, vol.6
, pp. 689-697
-
-
Saveanu, L.1
Carroll, O.2
Lindo, V.3
Del Val, M.4
Lopez, D.5
Lepelletier, Y.6
Greer, F.7
Schomburg, L.8
Fruci, D.9
Niedermann, G.10
Van Endert, P.M.11
-
59
-
-
35748981184
-
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants
-
Wellcome Trust Case Control Consortium, Australo-Anglo-American Spondylitis Consortium (TASC) Burton, P.R., Clayton, D.G., Cardon, L.R., Craddock, N., Deloukas, P., Duncanson, A., Kwiatkowski, D.P., McCarthy, M.I., Ouwehand, W.H., Samani, N.J., Todd, J.A., Donnelly, P., Barrett, J.C., Davison, D., Easton, D., Evans, D.M., Leung, H.T., Marchini, J.L., Morris, A.P., Spencer, C.C., Tobin, M.D., Attwood, A.P., Boorman, J.P., Cant, B., Everson, U., Hussey, J.M., Jolley, J.D., Knight, A.S., Koch, K., Meech, E., Nutland, S., Prowse, C.V., Stevens, H.E., Taylor, N.C., Walters, G.R., Walker, N.M., Watkins, N.A., Winzer, T., Jones, R.W., McArdle, W.L., Ring, S.M., Strachan, D.P., Pembrey, M., Breen, G., St Clair, D., Caesar, S., Gordon-Smith, K., Jones, L., Fraser, C., Green, E.K., Grozeva, D., Hamshere, M.L., Holmans, P.A., Jones, I.R., Kirov, G., Moskivina, V., Nikolov, I., O'Donovan, M.C., Owen, M.J., Collier, D.A., Elkin, A., Farmer, A., Williamson, R., McGuffin, P., Young, A.H., Ferrier, I.N., Ball, S.G., Balmforth, A.J., Barrett, J.H., Bishop, T.D., Iles, M.M., Maqbool, A., Yuldasheva, N., Hall, A.S., Braund, P.S., Dixon, R.J., Mangino, M., Stevens, S., Thompson, J.R., Bredin, F., Tremelling, M., Parkes, M., Drummond, H., Lees, C.W., Nimmo, E.R., Satsangi, J., Fisher, S.A., Forbes, A., Lewis, C.M., Onnie, C.M., Prescott, N.J., Sanderson, J., Matthew, C.G., Barbour, J., Mohiuddin, M.K., Todhunter, C.E., Mansfield, J.C., Ahmad, T., Cummings, F.R., Jewell, D.P., Webster, J., Brown, M.J., Lathrop, M.G., Connell, J., Dominiczak, A., Marcano, C.A., Burke, B., Dobson, R., Gungadoo, J., Lee, K.L., Munroe, P.B., Newhouse, S.J., Onipinla, A., Wallace, C., Xue, M., Caulfield, M., Farrall, M., Barton, A. (2007) Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. Nat. Genet. 39, 1329-1337
-
(2007)
Nat. Genet.
, vol.39
, pp. 1329-1337
-
-
Burton, P.R.1
Clayton, D.G.2
Cardon, L.R.3
Craddock, N.4
Deloukas, P.5
Duncanson, A.6
Kwiatkowski, D.P.7
McCarthy, M.I.8
-
60
-
-
77955332608
-
Endoplasmic reticulum aminopeptidases: Biology and pathogenic potential
-
Haroon, N. and Inman, R.D. (2010) Endoplasmic reticulum aminopeptidases: Biology and pathogenic potential. Nat. Rev. Rheumatol. 6, 461-467
-
(2010)
Nat. Rev. Rheumatol.
, vol.6
, pp. 461-467
-
-
Haroon, N.1
Inman, R.D.2
-
61
-
-
77950331522
-
Association of an ERAP1 ERAP2 haplotype with familial ankylosing spondylitis
-
Tsui, F.W., Haroon, N., Reveille, J.D., Rahman, P., Chiu, B., Tsui, H.W., and Inman, R.D. (2010) Association of an ERAP1 ERAP2 haplotype with familial ankylosing spondylitis. Ann. Rheum. Dis. 69, 733-736
-
(2010)
Ann. Rheum. Dis.
, vol.69
, pp. 733-736
-
-
Tsui, F.W.1
Haroon, N.2
Reveille, J.D.3
Rahman, P.4
Chiu, B.5
Tsui, H.W.6
Inman, R.D.7
-
62
-
-
79960899377
-
Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility
-
Evans, D.M., Spencer, C.C., Pointon, J.J., Su, Z., Harvey, D., Kochan, G., Oppermann, U., Dilthey, A., Pirinen, M., Stone, M.A., Appleton, L., Moutsianas, L., Leslie, S., Wordsworth, T., Kenna, T.J., Karaderi, T., Thomas, G.P., Ward, M.M., Weisman, M.H., Farrar, C., Bradbury, L.A., Danoy, P., Inman, R.D., Maksymowych, W., Gladman, D., Rahman, P. (2011) Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility. Nat. Genet. 43, 761-767
-
(2011)
Nat. Genet.
, vol.43
, pp. 761-767
-
-
Evans, D.M.1
Spencer, C.C.2
Pointon, J.J.3
Su, Z.4
Harvey, D.5
Kochan, G.6
Oppermann, U.7
Dilthey, A.8
Pirinen, M.9
Stone, M.A.10
Appleton, L.11
Moutsianas, L.12
Leslie, S.13
Wordsworth, T.14
Kenna, T.J.15
Karaderi, T.16
Thomas, G.P.17
Ward, M.M.18
Weisman, M.H.19
Farrar, C.20
Bradbury, L.A.21
Danoy, P.22
Inman, R.D.23
Maksymowych, W.24
Gladman, D.25
Rahman, P.26
more..
-
63
-
-
75749085686
-
Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci
-
Australo-Anglo-American Spondyloarthritis Consortium (TASC)
-
Australo-Anglo-American Spondyloarthritis Consortium (TASC) Reveille, J.D., Sims, A.M., Danoy, P., Evans, D.M., Leo, P., Pointon, J.J., Jin, R., Zhou, X., Bradbury, L.A., Appleton, L.H., Davis, J.C., Diekman, L., Doan, T., Dowling, A., Duan, R., Duncan, E.L., Farrar, C., Hadler, J., Harvey, D., Karaderi, T., Mogg, R., Pomeroy, E., Pryce, K., Taylor, J., Savage, L., Deloukas, P., Kumanduri, V., Peltonen, L., Ring, S.M., Whittaker, P., Glazov, E., Thomas, G.P., Maksymowych, W.P., Inman, R.D., Ward, M.M., Stone, M.A., Weisman, M.H., Wordsworth, B.P., and Brown, M.A. (2010) Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci. Nat. Genet. 42, 123-127
-
(2010)
Nat. Genet.
, vol.42
, pp. 123-127
-
-
Reveille, J.D.1
Sims, A.M.2
Danoy, P.3
Evans, D.M.4
Leo, P.5
Pointon, J.J.6
Jin, R.7
Zhou, X.8
Bradbury, L.A.9
Appleton, L.H.10
Davis, J.C.11
Diekman, L.12
Doan, T.13
Dowling, A.14
Duan, R.15
Duncan, E.L.16
Farrar, C.17
Hadler, J.18
Harvey, D.19
Karaderi, T.20
Mogg, R.21
Pomeroy, E.22
Pryce, K.23
Taylor, J.24
Savage, L.25
Deloukas, P.26
Kumanduri, V.27
Peltonen, L.28
Ring, S.M.29
Whittaker, P.30
Glazov, E.31
Thomas, G.P.32
Maksymowych, W.P.33
Inman, R.D.34
Ward, M.M.35
Stone, M.A.36
Weisman, M.H.37
Wordsworth, B.P.38
Brown, M.A.39
more..
-
64
-
-
75749134196
-
Genetics of ankylosing spondylitis
-
Brown, M.A. (2010) Genetics of ankylosing spondylitis. Curr. Opin. Rheumatol. 22, 126-132
-
(2010)
Curr. Opin. Rheumatol.
, vol.22
, pp. 126-132
-
-
Brown, M.A.1
-
65
-
-
14944345403
-
HLA-B27-restricted CD8+ T cell response to cartilage-derived self peptides in ankylosing spondylitis
-
Atagunduz, P., Appel, H., Kuon, W., Wu, P., Thiel, A., Kloetzel, P., and Sieper, J. (2005) HLA-B27-restricted CD8+ T cell response to cartilage-derived self peptides in ankylosing spondylitis. Arthritis Rheum. 52, 892-901
-
(2005)
Arthritis Rheum.
, vol.52
, pp. 892-901
-
-
Atagunduz, P.1
Appel, H.2
Kuon, W.3
Wu, P.4
Thiel, A.5
Kloetzel, P.6
Sieper, J.7
-
66
-
-
0027328672
-
HLA-B27-restricted CD8 T cells derived from synovial fluids of patients with reactive arthritis and ankylosing spondylitis
-
Hermann, E., Meyer zum Büschenfelde, K., Fleischer, B., and Yu, D.T.Y. (1993) HLA-B27-restricted CD8 T cells derived from synovial fluids of patients with reactive arthritis and ankylosing spondylitis. Lancet 342, 646-650
-
(1993)
Lancet
, vol.342
, pp. 646-650
-
-
Hermann, E.1
Meyerzum Büschenfelde, K.2
Fleischer, B.3
Yu, D.T.Y.4
-
67
-
-
79951817611
-
Coding single nucleotide polymorphisms of endoplasmic reticulum aminopeptidase 1 can affect antigenic peptide generation in vitro by influencing basic enzymatic properties of the enzyme
-
Evnouchidou, I., Kamal, R.P., Seregin, S.S., Goto, Y., Tsujimoto, M., Hattori, A., Voulgari, P.V., Drosos, A.A., Amalfitano, A., York, I.A., and Stratikos, E. (2011) Coding single nucleotide polymorphisms of endoplasmic reticulum aminopeptidase 1 can affect antigenic peptide generation in vitro by influencing basic enzymatic properties of the enzyme. J. Immunol. 186, 1909-1913
-
(2011)
J. Immunol.
, vol.186
, pp. 1909-1913
-
-
Evnouchidou, I.1
Kamal, R.P.2
Seregin, S.S.3
Goto, Y.4
Tsujimoto, M.5
Hattori, A.6
Voulgari, P.V.7
Drosos, A.A.8
Amalfitano, A.9
York, I.A.10
Stratikos, E.11
-
68
-
-
84869219870
-
Functional interaction of the ankylosing spondylitisassociated endoplasmic reticulum aminopeptidase 1 polymorphism and HLA-B27 in vivo
-
Garcia-Medel, N., Sanz-Bravo, A., Van Nguyen, D., Galocha, B., Gomez-Molina, P., Martin-Esteban, A., Alvarez-Navarro, C., and de Castro, J.A. (2012) Functional interaction of the ankylosing spondylitisassociated endoplasmic reticulum aminopeptidase 1 polymorphism and HLA-B27 in vivo. Mol. Cell. Proteomics 11, 1416-1429
-
(2012)
Mol. Cell. Proteomics
, vol.11
, pp. 1416-1429
-
-
Garcia-Medel, N.1
Sanz-Bravo, A.2
Van Nguyen, D.3
Galocha, B.4
Gomez-Molina, P.5
Martin-Esteban, A.6
Alvarez-Navarro, C.7
De Castro, J.A.8
-
69
-
-
84859449946
-
Exon 10 coding sequence is important for endoplasmic reticulum retention of endoplasmic reticulum aminopeptidase 1
-
Hattori, A., Goto, Y., and Tsujimoto, M. (2012) Exon 10 coding sequence is important for endoplasmic reticulum retention of endoplasmic reticulum aminopeptidase 1. Biol. Pharm. Bull. 35, 601-605
-
(2012)
Biol. Pharm. Bull.
, vol.35
, pp. 601-605
-
-
Hattori, A.1
Goto, Y.2
Tsujimoto, M.3
-
70
-
-
0345735829
-
Shedding of the type II IL-1 decoy receptor requires a multifunctional aminopeptidase, aminopeptidase regulator of TNF receptor type 1 shedding
-
Cui, X., Rouhani, F.N., Hawari, F., and Levine, S.J. (2003) Shedding of the type II IL-1 decoy receptor requires a multifunctional aminopeptidase, aminopeptidase regulator of TNF receptor type 1 shedding. J. Immunol. 171, 6814-6819
-
(2003)
J. Immunol.
, vol.171
, pp. 6814-6819
-
-
Cui, X.1
Rouhani, F.N.2
Hawari, F.3
Levine, S.J.4
-
71
-
-
0042206848
-
An aminopeptidase, ARTS-1, is required for interleukin-6 receptor shedding
-
Cui, X., Rouhani, F.N., Hawari, F., and Levine, S.J. (2003) An aminopeptidase, ARTS-1, is required for interleukin-6 receptor shedding. J. Biol. Chem. 278, 28677-28685
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 28677-28685
-
-
Cui, X.1
Rouhani, F.N.2
Hawari, F.3
Levine, S.J.4
-
72
-
-
43749104010
-
An association between RBMX, a heterogeneous nuclear ribonucleoprotein, and ARTS-1 regulates extracellular TNFR1 release
-
Adamik, B., Islam, A., Rouhani, F.N., Hawari, F.I., Zhang, J., and Levine, S.J. (2008) An association between RBMX, a heterogeneous nuclear ribonucleoprotein, and ARTS-1 regulates extracellular TNFR1 release. Biochem. Biophys. Res. Commun. 371, 505-509
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.371
, pp. 505-509
-
-
Adamik, B.1
Islam, A.2
Rouhani, F.N.3
Hawari, F.I.4
Zhang, J.5
Levine, S.J.6
-
73
-
-
33646547337
-
Extracellular TNFR1 release requires the calcium-dependent formation of a nucleobindin 2-ARTS-1 complex
-
Islam, A., Adamik, B., Hawari, F.I., Ma, G., Rouhani, F.N., Zhang, J., and Levine, S.J. (2006) Extracellular TNFR1 release requires the calcium-dependent formation of a nucleobindin 2-ARTS-1 complex. J. Biol. Chem. 281, 6860-6873
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 6860-6873
-
-
Islam, A.1
Adamik, B.2
Hawari, F.I.3
Ma, G.4
Rouhani, F.N.5
Zhang, J.6
Levine, S.J.7
-
74
-
-
79958709420
-
Secretion of endoplasmic reticulum aminopeptidase 1 is involved in the activation of macrophages induced by lipopolysaccharide and interferon-gamma
-
Goto, Y., Ogawa, K., Hattori, A., and Tsujimoto, M. (2011) Secretion of endoplasmic reticulum aminopeptidase 1 is involved in the activation of macrophages induced by lipopolysaccharide and interferon-gamma. J. Biol. Chem. 286, 21906-21914
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 21906-21914
-
-
Goto, Y.1
Ogawa, K.2
Hattori, A.3
Tsujimoto, M.4
-
75
-
-
4143112498
-
Distribution of adipocyte-derived leucine aminopeptidase (A-LAP)/ER-aminopeptidase (ERAP)-1 in human uterine endometrium
-
Shibata, D., Ando, H., Iwase, A., Nagasaka, T., Hattori, A., Tsujimoto, M., and Mizutani, S. (2004) Distribution of adipocyte-derived leucine aminopeptidase (A-LAP)/ER-aminopeptidase (ERAP)-1 in human uterine endometrium. J. Histochem. Cytochem. 52, 1169-1175
-
(2004)
J. Histochem. Cytochem.
, vol.52
, pp. 1169-1175
-
-
Shibata, D.1
Ando, H.2
Iwase, A.3
Nagasaka, T.4
Hattori, A.5
Tsujimoto, M.6
Mizutani, S.7
-
76
-
-
33645754224
-
Expression of endoplasmic reticulum aminopeptidases in EBV-B cell lines from healthy donors and in leukemia/lymphoma, carcinoma, and melanoma cell lines
-
Fruci, D., Ferracuti, S., Limongi, M.Z., Cunsolo, V., Giorda, E., Fraioli, R., Sibilio, L., Carroll, O., Hattori, A., Van Endert, P.M., and Giacomini, P. (2006) Expression of endoplasmic reticulum aminopeptidases in EBV-B cell lines from healthy donors and in leukemia/lymphoma, carcinoma, and melanoma cell lines. J. Immunol. 176, 4869-4879
-
(2006)
J. Immunol.
, vol.176
, pp. 4869-4879
-
-
Fruci, D.1
Ferracuti, S.2
Limongi, M.Z.3
Cunsolo, V.4
Giorda, E.5
Fraioli, R.6
Sibilio, L.7
Carroll, O.8
Hattori, A.9
Van Endert, P.M.10
Giacomini, P.11
-
77
-
-
80052966924
-
Human cytomegalovirus microRNA miR-US4-1 inhibits CD8(+) T cell responses by targeting the aminopeptidase ERAP1
-
Kim, S., Lee, S., Shin, J., Kim, Y., Evnouchidou, I., Kim, D., Kim, Y.K., Kim, Y.E., Ahn, J.H., Riddell, S.R., Stratikos, E., Kim, V.N., and Ahn, K. (2011) Human cytomegalovirus microRNA miR-US4-1 inhibits CD8(+) T cell responses by targeting the aminopeptidase ERAP1. Nat. Immunol. 12, 984-991
-
(2011)
Nat. Immunol.
, vol.12
, pp. 984-991
-
-
Kim, S.1
Lee, S.2
Shin, J.3
Kim, Y.4
Evnouchidou, I.5
Kim, D.6
Kim, Y.K.7
Kim, Y.E.8
Ahn, J.H.9
Riddell, S.R.10
Stratikos, E.11
Kim, V.N.12
Ahn, K.13
-
78
-
-
0036192091
-
Identification of 33 polymorphisms in the adipocyte-derived leucine aminopeptidase (ALAP) gene and possible association with hypertension
-
Yamamoto, N., Nakayama, J., Yamakawa-Kobayashi, K., Hamaguchi, H., Miyazaki, R., and Arinami, T. (2002) Identification of 33 polymorphisms in the adipocyte-derived leucine aminopeptidase (ALAP) gene and possible association with hypertension. Hum. Mutat. 19, 251-257
-
(2002)
Hum. Mutat.
, vol.19
, pp. 251-257
-
-
Yamamoto, N.1
Nakayama, J.2
Yamakawa-Kobayashi, K.3
Hamaguchi, H.4
Miyazaki, R.5
Arinami, T.6
-
79
-
-
3042588233
-
Adipocyte-derived leucine aminopeptidase genotype and response to antihypertensive therapy
-
Hallberg, P., Lind, L., Michaelsson, K., Kurland, L., Kahan, T., Malmqvist, K., Ohman, K.P., Nystrom, F., Liljedahl, U., Syvanen, A.C., and Melhus, H. (2003) Adipocyte-derived leucine aminopeptidase genotype and response to antihypertensive therapy. BMC Cardiovasc. Disord. 3, 11
-
(2003)
BMC Cardiovasc. Disord.
, vol.3
, pp. 11
-
-
Hallberg, P.1
Lind, L.2
Michaelsson, K.3
Kurland, L.4
Kahan, T.5
Malmqvist, K.6
Ohman, K.P.7
Nystrom, F.8
Liljedahl, U.9
Syvanen, A.C.10
Melhus, H.11
-
80
-
-
78049329814
-
Association analyses identify six new psoriasis susceptibility loci in the Chinese population
-
Sun, L.D., Cheng, H., Wang, Z.X., Zhang, A.P., Wang, P.G., Xu, J.H., Zhu, Q.X., Zhou, H.S., Ellinghaus, E., Zhang, F.R., Pu, X.M., Yang, X.Q., Zhang, J.Z., Xu, A.E., Wu, R.N., Xu, L.M., Peng, L., Helms, C.A., Ren, Y.Q., Zhang, C., Zhang, S.M., Nair, R.P., Wang, H.Y., Lin, G.S., Stuart, P.E., Fan, X., Chen, G., Tejasvi, T., Li, P., Zhu, J., Li, Z.M., Ge, H.M., Weichenthal, M., Ye, W.Z., Zhang, C., Shen, S.K., Yang, B.Q., Sun, Y.Y., Li, S.S., Lin, Y., Jiang, J.H., Li, C.T., Chen, R.X., Cheng, J., Jiang, X., Zhang, P., Song, W.M., Tang, J., Zhang, H.Q., Sun, L., Cui, J., Zhang, L.J., Tang, B., Huang, F., Qin, Q., Pei, X.P., Zhou, A.M., Shao, L.M., Liu, J.L., Zhang, F.Y., Du, W.D., Franke, A., Bowcock, A.M., Elder, J.T., Liu, J.J., Yang, S., and Zhang, X.J. (2010) Association analyses identify six new psoriasis susceptibility loci in the Chinese population. Nat. Genet. 42, 1005-1009
-
(2010)
Nat. Genet.
, vol.42
, pp. 1005-1009
-
-
Sun, L.D.1
Cheng, H.2
Wang, Z.X.3
Zhang, A.P.4
Wang, P.G.5
Xu, J.H.6
Zhu, Q.X.7
Zhou, H.S.8
Ellinghaus, E.9
Zhang, F.R.10
Pu, X.M.11
Yang, X.Q.12
Zhang, J.Z.13
Xu, A.E.14
Wu, R.N.15
Xu, L.M.16
Peng, L.17
Helms, C.A.18
Ren, Y.Q.19
Zhang, C.20
Zhang, S.M.21
Nair, R.P.22
Wang, H.Y.23
Lin, G.S.24
Stuart, P.E.25
Fan, X.26
Chen, G.27
Tejasvi, T.28
Li, P.29
Zhu, J.30
Li, Z.M.31
Ge, H.M.32
Weichenthal, M.33
Ye, W.Z.34
Zhang, C.35
Shen, S.K.36
Yang, B.Q.37
Sun, Y.Y.38
Li, S.S.39
Lin, Y.40
Jiang, J.H.41
Li, C.T.42
Chen, R.X.43
Cheng, J.44
Jiang, X.45
Zhang, P.46
Song, W.M.47
Tang, J.48
Zhang, H.Q.49
Sun, L.50
Cui, J.51
Zhang, L.J.52
Tang, B.53
Huang, F.54
Qin, Q.55
Pei, X.P.56
Zhou, A.M.57
Shao, L.M.58
Liu, J.L.59
Zhang, F.Y.60
Du, W.D.61
Franke, A.62
Bowcock, A.M.63
Elder, J.T.64
Liu, J.J.65
Yang, S.66
Zhang, X.J.67
more..
-
81
-
-
78049347495
-
A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1
-
Genetic Analysis of Psoriasis Consortium & the Wellcome Trust Case Control Consortium 2
-
Genetic Analysis of Psoriasis Consortium & the Wellcome Trust Case Control Consortium 2 Strange, A., Capon, F., Spencer, C.C., Knight, J., Weale, M.E., Allen, M.H., Barton, A., Band, G., Bellenguez, C., Bergboer, J.G., Blackwell, J.M., Bramon, E., Bumpstead, S.J., Casas, J.P., Cork, M.J., Corvin, A., Deloukas, P., Dilthey, A., Duncanson, A., Edkins, S., Estivill, X., Fitzgerald, O., Freeman, C., Giardina, E., Gray, E., Hofer, A., Huffmeier, U., Hunt, S.E., Irvine, A.D., Jankowski, J., Kirby, B., Langford, C., Lascorz, J., Leman, J., Leslie, S., Mallbris, L., Markus, H.S., Mathew, C.G., McLean, W.H., McManus, R., Mossner, R., Moutsianas, L., Naluai, A.T., Nestle, F.O., Novelli, G., Onoufriadis, A., Palmer, C.N., Perricone, C., Pirinen, M., Plomin, R., Potter, S.C., Pujol, R.M., Rautanen, A., Riveira-Munoz, E., Ryan, A.W., Salmhofer, W., Samuelsson, L., Sawcer, S.J., Schalkwijk, J., Smith, C.H., Stahle, M., Su, Z., Tazi-Ahnini, R., Traupe, H., Viswanathan, A.C., Warren, R.B., Weger, W., Wolk, K., Wood, N., Worthington, J., Young, H.S., Zeeuwen, P.L., Hayday, A., Burden, A.D., Griffiths, C.E., Kere, J., Reis, A., McVean, G., Evans, D.M., Brown, M.A., Barker, J.N., Peltonen, L., Donnelly, P., and Trembath, R.C. (2010) A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1. Nat. Genet. 42, 985-990
-
(2010)
Nat. Genet.
, vol.42
, pp. 985-990
-
-
Strange, A.1
Capon, F.2
Spencer, C.C.3
Knight, J.4
Weale, M.E.5
Allen, M.H.6
Barton, A.7
Band, G.8
Bellenguez, C.9
Bergboer, J.G.10
Blackwell, J.M.11
Bramon, E.12
Bumpstead, S.J.13
Casas, J.P.14
Cork, M.J.15
Corvin, A.16
Deloukas, P.17
Dilthey, A.18
Duncanson, A.19
Edkins, S.20
Estivill, X.21
Fitzgerald, O.22
Freeman, C.23
Giardina, E.24
Gray, E.25
Hofer, A.26
Huffmeier, U.27
Hunt, S.E.28
Irvine, A.D.29
Jankowski, J.30
Kirby, B.31
Langford, C.32
Lascorz, J.33
Leman, J.34
Leslie, S.35
Mallbris, L.36
Markus, H.S.37
Mathew, C.G.38
McLean, W.H.39
McManus, R.40
Mossner, R.41
Moutsianas, L.42
Naluai, A.T.43
Nestle, F.O.44
Novelli, G.45
Onoufriadis, A.46
Palmer, C.N.47
Perricone, C.48
Pirinen, M.49
Plomin, R.50
Potter, S.C.51
Pujol, R.M.52
Rautanen, A.53
Riveira-Munoz, E.54
Ryan, A.W.55
Salmhofer, W.56
Samuelsson, L.57
Sawcer, S.J.58
Schalkwijk, J.59
Smith, C.H.60
Stahle, M.61
Su, Z.62
Tazi-Ahnini, R.63
Traupe, H.64
Viswanathan, A.C.65
Warren, R.B.66
Weger, W.67
Wolk, K.68
Wood, N.69
Worthington, J.70
Young, H.S.71
Zeeuwen, P.L.72
Hayday, A.73
Burden, A.D.74
Griffiths, C.E.75
Kere, J.76
Reis, A.77
McVean, G.78
Evans, D.M.79
Brown, M.A.80
Barker, J.N.81
Peltonen, L.82
Donnelly, P.83
Trembath, R.C.84
more..
-
82
-
-
84855764355
-
A functional variant in ERAP1 predisposes to multiple sclerosis
-
Guerini, F.R., Cagliani, R., Forni, D., Agliardi, C., Caputo, D., Cassinotti, A., Galimberti, D., Fenoglio, C., Biasin, M., Asselta, R., Scarpini, E., Comi, G.P., Bresolin, N., Clerici, M., and Sironi, M. (2012) A functional variant in ERAP1 predisposes to multiple sclerosis. PLoS One 7, e29931
-
(2012)
PLoS One
, vol.7
-
-
Guerini, F.R.1
Cagliani, R.2
Forni, D.3
Agliardi, C.4
Caputo, D.5
Cassinotti, A.6
Galimberti, D.7
Fenoglio, C.8
Biasin, M.9
Asselta, R.10
Scarpini, E.11
Comi, G.P.12
Bresolin, N.13
Clerici, M.14
Sironi, M.15
-
83
-
-
84873091770
-
Genomewide association analysis identifies new susceptibility loci for Behç et's disease and epistasis between HLAB and ERAP1
-
Kirino, Y., Bertsias, G., Ishigatsubo, Y., Mizuki, N., Tugal-Tutkun, I., Seyahi, E., Ozyazgan, Y., Sacli, F.S., Erer, B., Inoko, H., Emrence, Z., Cakar, A., Abaci, N., Ustek, D., Satorius, C., Ueda, A., Takeno, M., Kim, Y., Wood, G.M., Ombrello, M.J., Meguro, A., Gül, A., Remmers, E.F., and Kastner, D.L (2013) Genomewide association analysis identifies new susceptibility loci for Behç et's disease and epistasis between HLAB.and ERAP1. Nat. Genet. 45, 202-207
-
(2013)
Nat. Genet.
, vol.45
, pp. 202-207
-
-
Kirino, Y.1
Bertsias, G.2
Ishigatsubo, Y.3
Mizuki, N.4
Tugal-Tutkun, I.5
Seyahi, E.6
Ozyazgan, Y.7
Sacli, F.S.8
Erer, B.9
Inoko, H.10
Emrence, Z.11
Cakar, A.12
Abaci, N.13
Ustek, D.14
Satorius, C.15
Ueda, A.16
Takeno, M.17
Kim, Y.18
Wood, G.M.19
Ombrello, M.J.20
Meguro, A.21
Gül, A.22
Remmers, E.F.23
Kastner, D.L.24
more..
-
84
-
-
78649489009
-
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
-
Franke, A., McGovern, D.P., Barrett, J.C., Wang, K., Radford-Smith, G.L., Ahmad, T., Lees, C.W., Balschun, T., Lee, J., Roberts, R., Anderson, C.A., Bis, J.C., Bumpstead, S., Ellinghaus, D., Festen, E.M., Georges, M., Green, T., Haritunians, T., Jostins, L., Latiano, A., Mathew, C.G., Montgomery, G.W., Prescott, N.J., Raychaudhuri, S., Rotter, J.I., Schumm, P., Sharma, Y., Simms, L.A., Taylor, K.D., Whiteman, D., Wijmenga, C., Baldassano, R.N., Barclay, M., Bayless, T.M., Brand, S., Buning, C., Cohen, A., Colombel, J.F., Cottone, M., Stronati, L., Denson, T., De Vos, M., D'Inca, R., Dubinsky, M., Edwards, C., Florin, T., Franchimont, D., Gearry, R., Glas, J., Van Gossum, A., Guthery, S.L., Halfvarson, J., Verspaget, H.W., Hugot, J.P., Karban, A., Laukens, D., Lawrance, I., Lemann, M., Levine, A., Libioulle, C., Louis, E., Mowat, C., Newman, W., Panes, J., Phillips, A., Proctor, D.D., Regueiro, M., Russell, R., Rutgeerts, P., Sanderson, J., Sans, M., Seibold, F., Steinhart, A.H., Stokkers, P.C., Torkvist, L., Kullak-Ublick, G., Wilson, D., Walters, T., Targan, S.R., Brant, S.R., Rioux, J.D., D'Amato, M., Weersma, R.K., Kugathasan, S., Griffiths, A.M., Mansfield, J.C., Vermeire, S., Duerr, R.H., Silverberg, M.S., Satsangi, J., Schreiber, S., Cho, J.H., Annese, V., Hakonarson, H., Daly, M.J., and Parkes, M. (2010) Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Nat. Genet. 42, 1118-1125
-
(2010)
Nat. Genet.
, vol.42
, pp. 1118-1125
-
-
Franke, A.1
McGovern, D.P.2
Barrett, J.C.3
Wang, K.4
Radford-Smith, G.L.5
Ahmad, T.6
Lees, C.W.7
Balschun, T.8
Lee, J.9
Roberts, R.10
Anderson, C.A.11
Bis, J.C.12
Bumpstead, S.13
Ellinghaus, D.14
Festen, E.M.15
Georges, M.16
Green, T.17
Haritunians, T.18
Jostins, L.19
Latiano, A.20
Mathew, C.G.21
Montgomery, G.W.22
Prescott, N.J.23
Raychaudhuri, S.24
Rotter, J.I.25
Schumm, P.26
Sharma, Y.27
Simms, L.A.28
Taylor, K.D.29
Whiteman, D.30
Wijmenga, C.31
Baldassano, R.N.32
Barclay, M.33
Bayless, T.M.34
Brand, S.35
Buning, C.36
Cohen, A.37
Colombel, J.F.38
Cottone, M.39
Stronati, L.40
Denson, T.41
De Vos, M.42
D'Inca, R.43
Dubinsky, M.44
Edwards, C.45
Florin, T.46
Franchimont, D.47
Gearry, R.48
Glas, J.49
Van Gossum, A.50
Guthery, S.L.51
Halfvarson, J.52
Verspaget, H.W.53
Hugot, J.P.54
Karban, A.55
Laukens, D.56
Lawrance, I.57
Lemann, M.58
Levine, A.59
Libioulle, C.60
Louis, E.61
Mowat, C.62
Newman, W.63
Panes, J.64
Phillips, A.65
Proctor, D.D.66
Regueiro, M.67
Russell, R.68
Rutgeerts, P.69
Sanderson, J.70
Sans, M.71
Seibold, F.72
Steinhart, A.H.73
Stokkers, P.C.74
Torkvist, L.75
Kullak-Ublick, G.76
Wilson, D.77
Walters, T.78
Targan, S.R.79
Brant, S.R.80
Rioux, J.D.81
D'Amato, M.82
Weersma, R.K.83
Kugathasan, S.84
Griffiths, A.M.85
Mansfield, J.C.86
Vermeire, S.87
Duerr, R.H.88
Silverberg, M.S.89
Satsangi, J.90
Schreiber, S.91
Cho, J.H.92
Annese, V.93
Hakonarson, H.94
Daly, M.J.95
Parkes, M.96
more..
-
85
-
-
73949152236
-
The ERAP2 gene is associated with preeclampsia in Australian and Norwegian populations
-
Johnson, M.P., Roten, L.T., Dyer, T.D., East, C.E., Forsmo, S., Blangero, J., Brennecke, S.P., Austgulen, R., and Moses, E.K. (2009) The ERAP2 gene is associated with preeclampsia in Australian and Norwegian populations. Hum. Genet. 126, 655-666
-
(2009)
Hum. Genet.
, vol.126
, pp. 655-666
-
-
Johnson, M.P.1
Roten, L.T.2
Dyer, T.D.3
East, C.E.4
Forsmo, S.5
Blangero, J.6
Brennecke, S.P.7
Austgulen, R.8
Moses, E.K.9
-
86
-
-
78449233933
-
Balancing selection maintains a form of ERAP2 that undergoes nonsensemediated decay and affects antigen presentation
-
NISC Comparative Sequencing Program. In:.
-
Andres, A.M., Dennis, M.Y., Kretzschmar, W.W., Cannons, J.L., Lee-Lin, S.Q., Hurle, B., NISC Comparative Sequencing Program. In: Schwartzberg, P.L., Williamson, S.H., Bustamante, C.D., Nielsen, R., Clark, A.G., and Green, E.D. (2010) Balancing selection maintains a form of ERAP2 that undergoes nonsensemediated decay and affects antigen presentation. PLoS Genet 6, e1001157
-
(2010)
PLoS Genet
, vol.6
-
-
Andres, A.M.1
Dennis, M.Y.2
Kretzschmar, W.W.3
Cannons, J.L.4
Lee-Lin, S.Q.5
Hurle, B.6
Schwartzberg, P.L.7
Williamson, S.H.8
Bustamante, C.D.9
Nielsen, R.10
Clark, A.G.11
Green, E.D.12
-
87
-
-
84879885253
-
Endoplasmic reticulum aminopeptidase 2 (ERAP2) haplotypes play a role in modulating susceptibility to HIV infection
-
Biasin, M., Sironi, M., Saulle, I., de Luca, M., la Rosa, F., Cagliani, R., Forni, D., Agliardi, C., Caputo, S.L., Mazzotta, F., Trabattoni, D., Macias, J., Pineda, J.A., Caruz, A., and Clerici, M. (2013) Endoplasmic reticulum aminopeptidase 2 (ERAP2) haplotypes play a role in modulating susceptibility to HIV infection. AIDS 27, 1697-1706
-
(2013)
AIDS
, vol.27
, pp. 1697-1706
-
-
Biasin, M.1
Sironi, M.2
Saulle, I.3
De Luca, M.4
La Rosa, F.5
Cagliani, R.6
Forni, D.7
Agliardi, C.8
Caputo, S.L.9
Mazzotta, F.10
Trabattoni, D.11
Macias, J.12
Pineda, J.A.13
Caruz, A.14
Clerici, M.15
-
88
-
-
78149277185
-
Genetic diversity at endoplasmic reticulum aminopeptidases is maintained by balancing selection and is associated with natural resistance to HIV-1 infection
-
Cagliani, R., Riva, S., Biasin, M., Fumagalli, M., Pozzoli, U., Lo Caputo, S., Mazzotta, F., Piacentini, L., Bresolin, N., Clerici, M., and Sironi, M. (2010) Genetic diversity at endoplasmic reticulum aminopeptidases is maintained by balancing selection and is associated with natural resistance to HIV-1 infection. Hum. Mol. Genet. 19, 4705-4714
-
(2010)
Hum. Mol. Genet.
, vol.19
, pp. 4705-4714
-
-
Cagliani, R.1
Riva, S.2
Biasin, M.3
Fumagalli, M.4
Pozzoli, U.5
Lo Caputo, S.6
Mazzotta, F.7
Piacentini, L.8
Bresolin, N.9
Clerici, M.10
Sironi, M.11
|