A Role for a Novel Luminal Endoplasmic Reticulum Aminopeptidase in Final Trimming of 26 S Proteasome-generated Major Histocompatability Complex Class I Antigenic Peptides

Journal of Biological Chemistry

Volumn 276, Issue 32, 2001, Pages 30050-30056

  Komlosh, Arthur ^a   Momburg, Frank ^b   Weinschenk, Toni ^c   Emmerich, Niels ^c   Schild, Hansjörg ^c   Nadav, Eran ^a   Shaked, Isabella ^a   Reiss, Yuval ^a  

^a TEL AVIV UNIVERSITY   (Israel)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^c UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; ANTIGENS; BIOCOMPATIBILITY; ENZYME KINETICS; HISTOLOGY;

HISTOCOMPATABILITY;

BIOCHEMISTRY;

1,10 PHENANTHROLINE; 26 S PROTEASOME; AMINO ACID; AMINOPEPTIDASE; ASTRINGENT AGENT; CARRIER PROTEIN; EDETIC ACID; EPITOPE; LEUCYLGLUTAMYLSERYLISOLEUCYLISOLEUCYLASPARAGINYLPHENYLALANYLGLUTAMYLLYSYLLE UCINE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; METALLOPROTEINASE; METALLOPROTEINASE INHIBITOR; ORNITHINE DECARBOXYLASE; OVALBUMIN; PEPTIDE; PROTEASOME; PROTEIN TAP; RECOMBINANT ENZYME; SERYLISOLEUCYLISOLEUCYLASPARAGINYLPHENYLALANYLGLUTAMYLLYSYLLEUCINE; SODIUM CHLORIDE; UNCLASSIFIED DRUG; 1,10-PHENANTHROLINE; ATP DEPENDENT 26S PROTEASE; ENZYME INHIBITOR; HYBRID PROTEIN; PEPTIDE HYDROLASE; PHENANTHROLINE DERIVATIVE; RECOMBINANT PROTEIN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANTIGEN PRESENTATION; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL FREE SYSTEM; CYTOTOXIC T LYMPHOCYTE; ENDOPLASMIC RETICULUM; ENZYME DEGRADATION; MAJOR HISTOCOMPATIBILITY COMPLEX; MICROSOME; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROCESSING; ANIMAL; BAGG ALBINO MOUSE; C57BL MOUSE; CELL FRACTIONATION; CELL LINE; CHEMISTRY; CYTOSOL; DOSE RESPONSE; DRUG ANTAGONISM; ENZYMOLOGY; GENE; GENETICS; MASS SPECTROMETRY; METABOLISM; PROTEIN TRANSPORT; TIME;

ANIMALIA;

AMINO ACIDS; AMINOPEPTIDASES; ANIMALS; CELL LINE; CELL-FREE SYSTEM; CYTOSOL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOPLASMIC RETICULUM; ENZYME INHIBITORS; EPITOPES; GENES, MHC CLASS I; MASS SPECTROMETRY; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICROSOMES; ORNITHINE DECARBOXYLASE; PEPTIDE HYDROLASES; PEPTIDES; PHENANTHROLINES; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN TRANSPORT; RECOMBINANT FUSION PROTEINS; RECOMBINANT PROTEINS; SUBCELLULAR FRACTIONS; TIME FACTORS;

EID: 0035839492     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M103177200     Document Type: Article

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