Gene batteries and synexpression groups applied in a multivariate statistical approach to dose-response analysis of toxicogenomic data

Regulatory Toxicology and Pharmacology

Volumn 67, Issue 1, 2013, Pages 63-74

  Parfett, C ^a   Williams, A ^a   Zheng, J L ^a   Zhou, G ^a  

^a Environmental Health Center   (Canada)

Author keywords

Adverse outcome; Point of departure; Risk assessment; Signal response; Stress response pathways

Indexed keywords

ISOPRENALINE; STAT3 PROTEIN;

ADVERSE OUTCOME; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIOTOXICITY; CHRONIC TOXICITY; CONTROLLED STUDY; DOSE RESPONSE; DOSIMETRY; GENE; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORK; GENE TARGETING; GENOMICS; LOW DRUG DOSE; MALE; MOUSE; MULTIVARIATE ANALYSIS; NFKB GENE; NONHUMAN; PRIORITY JOURNAL; STAT3 GENE; TOXICOGENETICS;

MURINAE; RATTUS;

ADVERSE OUTCOME; POINT OF DEPARTURE; RISK ASSESSMENT; SIGNAL RESPONSE; STRESS-RESPONSE PATHWAYS;

ADRENERGIC BETA-AGONISTS; ANIMALS; BENCHMARKING; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION; ISOPROTERENOL; LIVER; MALE; MICE; MULTIVARIATE ANALYSIS; RANDOM ALLOCATION; TOXICOGENETICS;

EID: 84883460122     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2013.06.005     Document Type: Article

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