Approaches to human health risk assessment based on the signal-to-noise crossover dose

Environmental Health Perspectives

Volumn 120, Issue 7, 2012, Pages

  Chiu, Weihsueh A ^a   Guyton, Kathryn Z ^a   Hogan, Karen ^a   Jinot, Jennifer ^a  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BIOASSAY; CARCINOGEN TESTING; ENVIRONMENTAL EXPOSURE; HEALTH HAZARD; HUMAN; MAXIMUM PERMISSIBLE DOSE; POINT OF DEPARTURE; PRIORITY JOURNAL; RISK ASSESSMENT; TOXICOLOGICAL PARAMETERS; TOXICOLOGY;

DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL EXPOSURE; HEALTH STATUS INDICATORS; HUMANS; MODELS, BIOLOGICAL; RISK ASSESSMENT; TOXICOLOGY;

EID: 84864120568     PISSN: 00916765     EISSN: 15529924     Source Type: Journal    
DOI: 10.1289/ehp.1205212     Document Type: Article

References (3)

1. National Research Council. 2009. Science and Decisions: Advancing Risk Assessment. Washington, DC:National Academies Press.
2. Sand S, Portier CJ, Krewski D. 2011. A signal-to-noise crossover dose as the point of departure for health risk assessment. Environ Health Perspect 119:1766-1774.
3. U.S. EPA (U.S. Environmental Protection Agency). 2005. Guidelines for Carcinogen Risk Assessment. EPA/630/P-03/001F. Washington, DC:U.S. EPA. Available: http://www.epa.gov/raf/publications/pdfs/CANCER_GUIDELINES_FINAL_3-25-05 .pdf [accessed 8June 2012].