Guanine nucleotide exchange factor-H1 signaling is involved in lipopolysaccharide-induced endothelial barrier dysfunction

Surgery (United States)

Volumn 154, Issue 3, 2013, Pages 621-631

  Zhou, Zengding ^a   Guo, Feng ^a   Dou, Yi ^a   Tang, Jiajun ^a   Huan, Jingning ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; ALBUMIN; CELL ADHESION MOLECULE; CELL PROTEIN; CLAUDIN 1; CYTOSKELETON PROTEIN; EVANS BLUE; F ACTIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANINE NUCLEOTIDE EXCHANGE FACTOR H1 SIGNALING PATHWAY; LIPOPOLYSACCHARIDE; MYOSIN ASSOCIATED PHOSPHATASE TYPE 1; MYOSIN LIGHT CHAIN; OCCLUDIN; PHOSPHOPROTEIN PHOSPHATASE 1; RHO FACTOR; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; VASCULAR ENDOTHELIAL CADHERIN;

ACTIN FILAMENT; ARTICLE; BLOOD VESSEL PERMEABILITY; CELL CONTACT; CELL CULTURE; CELL JUNCTION; CELL STRUCTURE; CONTROLLED STUDY; ENDOTHELIAL DYSFUNCTION; GENE SILENCING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; PERMEABILITY BARRIER; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RNA INTERFERENCE; SEPSIS; SIGNAL TRANSDUCTION; STRESS FIBER; UMBILICAL VEIN; WESTERN BLOTTING;

CAPILLARY PERMEABILITY; CYTOSKELETON; ENDOTHELIAL CELLS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; INTERCELLULAR JUNCTIONS; LIPOPOLYSACCHARIDES; RHO-ASSOCIATED KINASES; RHOA GTP-BINDING PROTEIN;

EID: 84883208525     PISSN: 00396060     EISSN: 15327361     Source Type: Journal    
DOI: 10.1016/j.surg.2013.04.009     Document Type: Article

References (59)

1. M. Wendel, R. Paul, and A.R. Heller Lipoproteins in inflammation and sepsis. II. Clinical aspects Intensive Care Med 33 2007 25 35
2. J.M. Cook-Mills, and T.L. Deem Active participation of endothelial cells in inflammation J Leukocyte Biol 77 2005 487 495
3. W.C. Aird The role of the endothelium in severe sepsis and multiple organ dysfunction syndrome Blood 101 2003 3765 3777
4. E. Dejana Endothelial cell-cell junctions: happy together Nat Rev Mol Cell Biol 5 2004 261 270
5. A.A. Birukova, K. Smurova, K.G. Birukov, K. Kaibuchi, J.G. Garcia, and A.D. Verin Role of Rho GTPases in thrombin-induced lung vascular endothelial cells barrier dysfunction Microvasc Res 67 2004 64 77
6. T.Y. Lee, and A.I. Gotlieb Microfilaments and microtubules maintain endothelial integrity Microsc Res Tech 60 2003 115 127
7. H. Lum, and A.B. Malik Mechanisms of increased endothelial permeability Can J Physiol Pharmacol 74 1996 787 800
8. N. Wettschureck, and S. Offermanns Rho/Rho-kinase mediated signaling in physiology and pathophysiology J Mol Med 80 2002 629 638
9. S.M. Dudek, and J.G. Garcia Cytoskeletal regulation of pulmonary vascular permeability J Appl Physiol 91 2001 1487 1500
10. T. Kaneko-Kawano, F. Takasu, H. Naoki, Y. Sakumura, S. Ishii, and T. Ueba Dynamic regulation of myosin light chain phosphorylation by Rho-kinase PLoS One 7 2012 e39269
11. C.A. Hudson, K.J. Heesom, and A. Lopez Bernal Phasic contractions of isolated human myometrium are associated with Rho-kinase (ROCK)-dependent phosphorylation of myosin phosphatase-targeting subunit (MYPT1) Mol Hum Reprod 18 2012 265 279
12. V. Spindler, N. Schlegel, and J. Waschke Role of GTPases in control of microvascular permeability Cardiovasc Res 87 2010 243 253
13. X. Wu, R. Guo, P. Chen, Q. Wang, and P.N. Cunningham TNF induces caspase-dependent inflammation in renal endothelial cells through a Rho- and myosin light chain kinase-dependent mechanism Am J Physiol Renal Physiol 297 2009 F316 F326
14. N.S. Umapathy, E.A. Zemskov, J. Gonzales, B.A. Gorshkov, S. Sridhar, and T. Chakraborty Extracellular beta-nicotinamide adenine dinucleotide (beta-NAD) promotes the endothelial cell barrier integrity via PKA- and EPAC1/Rac1-dependent actin cytoskeleton rearrangement J Cell Physiol 223 2010 215 223
15. N.V. Bogatcheva, M.A. Zemskova, C. Poirier, T. Mirzapoiazova, I. Kolosova, and A.R. Bresnick The suppression of myosin light chain (MLC) phosphorylation during the response to lipopolysaccharide (LPS): beneficial or detrimental to endothelial barrier? J Cell Physiol 226 2011 3132 3146
16. C.M. Beckers, V.W. van Hinsbergh, and G.P. van Nieuw Amerongen Driving Rho GTPase activity in endothelial cells regulates barrier integrity Thromb Haemost 103 2010 40 55
17. N. Schlegel, Y. Baumer, D. Drenckhahn, and J. Waschke Lipopolysaccharide-induced endothelial barrier breakdown is cyclic adenosine monophosphate dependent in vivo and in vitro Crit Care Med 37 2009 1735 1743
18. X. Peng, P.M. Hassoun, S. Sammani, B.J. McVerry, M.J. Burne, and H. Rabb Protective effects of sphingosine 1-phosphate in murine endotoxin-induced inflammatory lung injury Am J Respir Crit Care Med 169 2004 1245 1251
19. R. Coimbra, H. Melbostad, W. Loomis, R.D. Porcides, P. Wolf, and M. Tobar LPS-induced acute lung injury is attenuated by phosphodiesterase inhibition: effects on proinflammatory mediators, metalloproteinases, NF-kappaB, and ICAM-1 expression J Trauma 60 2006 115 125
20. Y. Liu, K. Ballman, D. Li, S. Khan, E. Derr-Yellin, and W. Shou Impaired function of Fanconi anemia type C-deficient macrophages J Leukocyte Biol 91 2012 333 340
21. P. Sen, R. Gopalakrishnan, H. Kothari, S. Keshava, C.A. Clark, and C.T. Esmon Factor VIIa bound to endothelial cell protein C receptor activates protease activated receptor-1 and mediates cell signaling and barrier protection Blood 117 2011 3199 3208
22. Y. Zheng Dbl family guanine nucleotide exchange factors Trends Biochem Sci 26 2001 724 732
23. Y. Ren, R. Li, Y. Zheng, and H. Busch Cloning and characterization of GEF-H1, a microtubule-associated guanine nucleotide exchange factor for Rac and Rho GTPases J Biol Chem 273 1998 34954 34960
24. M. Krendel, F.T. Zenke, and G.M. Bokoch Nucleotide exchange factor GEF-H1 mediates cross-talk between microtubules and the actin cytoskeleton Nat Cell Biol 4 2002 294 301
25. P.K. Chatterjee, M.M. Yeboah, O. Dowling, X. Xue, S.R. Powell, and Y. Al-Abed Nicotinic acetylcholine receptor agonists attenuate septic acute kidney injury in mice by suppressing inflammation and proteasome activity Plos One 7 2012 e35361
26. N. Isowa, A.M. Xavier, E. Dziak, M. Opas, D.I. McRitchie, and A.S. Slutsky LPS-induced depolymerization of cytoskeleton and its role in TNF-alpha production by rat pneumocytes Am J Physiol 277 1999 L606 L615
27. N. Isowa, S.H. Keshavjee, and M. Liu Role of microtubules in LPS-induced macrophage inflammatory protein-2 production from rat pneumocytes Am J Physiol Lung Cell Mol Physiol 279 2000 L1075 L1082
28. A.A. Birukova, K.G. Birukov, K. Smurova, D. Adyshev, K. Kaibuchi, and I. Alieva Novel role of microtubules in thrombin-induced endothelial barrier dysfunction FASEB J 18 2004 1879 1890
29. S.Q. Xu, K. Mahadev, X. Wu, L. Fuchsel, S. Donnelly, and R.G. Scalia Adiponectin protects against angiotensin II or tumor necrosis factor alpha-induced endothelial cell monolayer hyperpermeability: role of cAMP/PKA signaling Arterioscler Thromb Vasc Biol 28 2008 899 905
30. F. Guo, Z. Zhou, Y. Dou, J. Tang, C. Gao, and J. Huan GEF-H1/RhoA signalling pathway mediates lipopolysaccharide-induced intercellular adhesion molecular-1 expression in endothelial cells via activation of p38 and NF-kappaB Cytokine 57 2012 417 428
31. J.L. Shelton, L. Wang, G. Cepinskas, M. Sandig, R. Inculet, and D.G. McCormack Albumin leak across human pulmonary microvascular vs. umbilical vein endothelial cells under septic conditions Microvasc Res 71 2006 40 47
32. F. Guo, J. Tang, Z. Zhou, Y. Dou, D. Van Lonkhuyzen, and C. Gao GEF-H1-RhoA signaling pathway mediates LPS-induced NF-κB transactivation and IL-8 synthesis in endothelial cells Mol Immunol 50 2012 98 107
33. F. Guo, Y. Xing, Z. Zhou, Y. Dou, J. Tang, and C. Gao Guanine-nucleotide exchange factor H1 mediates lipopolysaccharide-induced interleukin 6 and tumor necrosis factor alpha expression in endothelial cells via activation of nuclear factor kappaB Shock 37 2012 531 538
34. R.S. Mali, B. Ramdas, P. Ma, J. Shi, V. Munugalavadla, and E. Sims Rho kinase regulates the survival and transformation of cells bearing oncogenic forms of KIT, FLT3, and BCR-ABL Cancer Cell 20 2011 357 369
35. J.S. Bae, and A.R. Rezaie Activated protein C inhibits high mobility group box 1 signaling in endothelial cells Blood 118 2011 3952 3959
36. J.W. Bae, and J.S. Bae Barrier protective effects of lycopene in human endothelial cells Inflamm Res 60 2011 751 758
37. S. Tasaka, H. Koh, W. Yamada, M. Shimizu, Y. Ogawa, and N. Hasegawa Attenuation of endotoxin-induced acute lung injury by the Rho-associated kinase inhibitor, Y-27632 Am J Respir Cell Mol Biol 32 2005 504 510
38. B. Wojciak-Stothard, and A.J. Ridley Rho GTPases and the regulation of endothelial permeability Vasc Pharmacol 39 2002 187 199
39. Y. Kawano, Y. Fukata, N. Oshiro, M. Amano, T. Nakamura, and M. Ito Phosphorylation of myosin-binding subunit (MBS) of myosin phosphatase by Rho-kinase in vivo J Cell Biol 147 1999 1023 1038
40. H. Eutamene, V. Theodorou, F. Schmidlin, V. Tondereau, R. Garcia-Villar, and C. Salvador-Cartier LPS-induced lung inflammation is linked to increased epithelial permeability: role of MLCK Eur Respir J 25 2005 789 796
41. J.A. McKenzie, and A.J. Ridley Roles of Rho/ROCK and MLCK in TNF-alpha-induced changes in endothelial morphology and permeability J Cell Physiol 213 2007 221 228
42. M. Furuse, H. Sasaki, K. Fujimoto, and S. Tsukita A single gene product, claudin-1 or -2, reconstitutes tight junction strands and recruits occludin in fibroblasts J Cell Biol 143 1998 391 401
43. T. Gustot Multiple organ failure in sepsis: prognosis and role of systemic inflammatory response Curr Opin Crit Care 17 2011 153 159
44. V.M. Braga Cell-cell adhesion and signalling Curr Opin Cell Biol 14 2002 546 556
45. M. Essler, J.M. Staddon, P.C. Weber, and M. Aepfelbacher Cyclic AMP blocks bacterial lipopolysaccharide-induced myosin light chain phosphorylation in endothelial cells through inhibition of Rho/Rho kinase signaling J Immunol 164 2000 6543 6549
46. A.A. Birukova, D. Adyshev, B. Gorshkov, G.M. Bokoch, K.G. Birukov, and A.D. Verin GEF-H1 is involved in agonist-induced human pulmonary endothelial barrier dysfunction Am J Physiol Lung Cell Mol Physiol 290 2006 L540 L548
47. J. Xing, and A.A. Birukova ANP attenuates inflammatory signaling and Rho pathway of lung endothelial permeability induced by LPS and TNFalpha Microvasc Res 79 2010 56 62
48. A.A. Birukova, P. Fu, J. Xing, B. Yakubov, I. Cokic, and K.G. Birukov Mechanotransduction by GEF-H1 as a novel mechanism of ventilator-induced vascular endothelial permeability Am J Physiol Lung Cell Mol Physiol 298 2010 L837 L848
49. C.C. Michel, and F.E. Curry Microvascular permeability Physiol Rev 79 1999 703 761
50. R.H. Adamson, F.E. Curry, G. Adamson, B. Liu, Y. Jiang, and K. Aktories Rho and rho kinase modulation of barrier properties: cultured endothelial cells and intact microvessels of rats and mice J Physiol 539 2002 295 308
51. N.V. Bogatcheva, and A.D. Verin The role of cytoskeleton in the regulation of vascular endothelial barrier function Microvasc Res 76 2008 202 207
52. J. Gavard, and J.S. Gutkind Protein kinase C-related kinase and ROCK are required for thrombin-induced endothelial cell permeability downstream from Galpha12/13 and Galpha11/q J Biol Chem 283 2008 29888 29896
53. Y.C. Chang, P. Nalbant, J. Birkenfeld, Z.F. Chang, and G.M. Bokoch GEF-H1 couples nocodazole-induced microtubule disassembly to cell contractility via RhoA Mol Biol Cell 19 2008 2147 2153
54. T. Matsuzawa, A. Kuwae, S. Yoshida, C. Sasakawa, and A. Abe Enteropathogenic Escherichia coli activates the RhoA signaling pathway via the stimulation of GEF-H1 EMBO J 23 2004 3570 3582
55. T. Mirzapoiazova, I.A. Kolosova, L. Moreno, S. Sammani, J.G. Garcia, and A.D. Verin Suppression of endotoxin-induced inflammation by taxol Eur Respir J 30 2007 429 435
56. G. Bazzoni, and E. Dejana Endothelial cell-to-cell junctions: molecular organization and role in vascular homeostasis Physiol Rev 84 2004 869 901
57. M.R. Popoff, and B. Geny Multifaceted role of Rho, Rac, Cdc42 and Ras in intercellular junctions, lessons from toxins Biochim Biophys Acta 1788 2009 797 812
58. S. Terry, M. Nie, K. Matter, and M.S. Balda Rho signaling and tight junction functions Physiology 25 2010 16 26
59. A.I. Ivanov, I.C. McCall, B. Babbin, S.N. Samarin, A. Nusrat, and C.A. Parkos Microtubules regulate disassembly of epithelial apical junctions BMC Cell Biol 7 2006 12