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Volumn 226, Issue 12, 2011, Pages 3132-3146

The suppression of myosin light chain (MLC) phosphorylation during the response to lipopolysaccharide (LPS): Beneficial or detrimental to endothelial barrier?

Author keywords

[No Author keywords available]

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; FORSKOLIN; LIPOPOLYSACCHARIDE; MYOSIN LIGHT CHAIN; MYOSIN LIGHT CHAIN KINASE; RHO KINASE; RHO KINASE 1; RHO KINASE 2; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

EID: 80053166480     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.22669     Document Type: Article
Times cited : (36)

References (47)
  • 2
    • 53649089268 scopus 로고    scopus 로고
    • The role of cytoskeleton in the regulation of vascular endothelial barrier function
    • Bogatcheva NV, Verin AD. 2008. The role of cytoskeleton in the regulation of vascular endothelial barrier function. Microvasc Res 76: 202-207.
    • (2008) Microvasc Res , vol.76 , pp. 202-207
    • Bogatcheva, N.V.1    Verin, A.D.2
  • 3
    • 70449726625 scopus 로고    scopus 로고
    • Molecular mechanisms mediating protective effect of cAMP on lipopolysaccharide (LPS)-induced human lung microvascular endothelial cells (HLMVEC) hyperpermeability
    • Bogatcheva NV, Zemskova MA, Kovalenkov Y, Poirier C, Verin AD. 2009. Molecular mechanisms mediating protective effect of cAMP on lipopolysaccharide (LPS)-induced human lung microvascular endothelial cells (HLMVEC) hyperpermeability. J Cell Physiol 221: 750-759.
    • (2009) J Cell Physiol , vol.221 , pp. 750-759
    • Bogatcheva, N.V.1    Zemskova, M.A.2    Kovalenkov, Y.3    Poirier, C.4    Verin, A.D.5
  • 4
    • 0028822081 scopus 로고
    • Phosphorylation on threonine-18 of the regulatory light chain dissociates the ATPase and motor properties of smooth muscle myosin II
    • Bresnick AR, Wolff-Long VL, Baumann O, Pollard TD. 1995. Phosphorylation on threonine-18 of the regulatory light chain dissociates the ATPase and motor properties of smooth muscle myosin II. Biochemistry 34: 12576-12583.
    • (1995) Biochemistry , vol.34 , pp. 12576-12583
    • Bresnick, A.R.1    Wolff-Long, V.L.2    Baumann, O.3    Pollard, T.D.4
  • 5
    • 0036550315 scopus 로고    scopus 로고
    • Role of vasodilator-stimulated phosphoprotein in PKA-induced changes in endothelial junctional permeability
    • Comerford KM, Lawrence DW, Synnestvedt K, Levi BP, Colgan SP. 2002. Role of vasodilator-stimulated phosphoprotein in PKA-induced changes in endothelial junctional permeability. FASEB J 16: 583-585.
    • (2002) FASEB J , vol.16 , pp. 583-585
    • Comerford, K.M.1    Lawrence, D.W.2    Synnestvedt, K.3    Levi, B.P.4    Colgan, S.P.5
  • 6
    • 35348875514 scopus 로고    scopus 로고
    • Regulation of vascular endothelial cell barrier function and cytoskeleton structure by protein phosphatases of the PPP family
    • Csortos C, Kolosova I, Verin AD. 2007. Regulation of vascular endothelial cell barrier function and cytoskeleton structure by protein phosphatases of the PPP family. Am J Physiol Lung Cell Mol Physiol 293: L843-L854.
    • (2007) Am J Physiol Lung Cell Mol Physiol , vol.293
    • Csortos, C.1    Kolosova, I.2    Verin, A.D.3
  • 7
    • 67650480778 scopus 로고    scopus 로고
    • The Rho-A/Rho-kinase pathway is up-regulated but remains inhibited by cyclic guanosine monophosphate-dependent mechanisms during endotoxemia in small mesenteric arteries
    • da Silva-Santos JE, Chiao CW, Leite R, Webb RC. 2009. The Rho-A/Rho-kinase pathway is up-regulated but remains inhibited by cyclic guanosine monophosphate-dependent mechanisms during endotoxemia in small mesenteric arteries. Crit Care Med 37: 1716-1723.
    • (2009) Crit Care Med , vol.37 , pp. 1716-1723
    • da Silva-Santos, J.E.1    Chiao, C.W.2    Leite, R.3    Webb, R.C.4
  • 8
    • 0034660145 scopus 로고    scopus 로고
    • Cyclic AMP blocks bacterial lipopolysaccharide-induced myosin light chain phosphorylation in endothelial cells through inhibition of Rho/Rho kinase signaling
    • Essler M, Staddon JM, Weber PC, Aepfelbacher M. 2000. Cyclic AMP blocks bacterial lipopolysaccharide-induced myosin light chain phosphorylation in endothelial cells through inhibition of Rho/Rho kinase signaling. J Immunol 164: 6543-6549.
    • (2000) J Immunol , vol.164 , pp. 6543-6549
    • Essler, M.1    Staddon, J.M.2    Weber, P.C.3    Aepfelbacher, M.4
  • 12
    • 0035150402 scopus 로고    scopus 로고
    • Rho-Rho-kinase pathway in smooth muscle contraction and cytoskeletal reorganization of non-muscle cells
    • Fukata Y, Amano M, Kaibuchi K. 2001. Rho-Rho-kinase pathway in smooth muscle contraction and cytoskeletal reorganization of non-muscle cells. Trends Pharmacol Sci 22: 32-39.
    • (2001) Trends Pharmacol Sci , vol.22 , pp. 32-39
    • Fukata, Y.1    Amano, M.2    Kaibuchi, K.3
  • 14
    • 0029119895 scopus 로고
    • Myosin light chain kinase-regulated endothelial cell contraction: The relationship between isometric tension, actin polymerization, and myosin phosphorylation
    • Goeckeler ZM, Wysolmerski RB. 1995. Myosin light chain kinase-regulated endothelial cell contraction: The relationship between isometric tension, actin polymerization, and myosin phosphorylation. J Cell Biol 130: 613-627.
    • (1995) J Cell Biol , vol.130 , pp. 613-627
    • Goeckeler, Z.M.1    Wysolmerski, R.B.2
  • 16
    • 0022410257 scopus 로고
    • Phosphorylation of smooth muscle myosin at two distinct sites by myosin light chain kinase
    • Ikebe M, Hartshorne DJ. 1985. Phosphorylation of smooth muscle myosin at two distinct sites by myosin light chain kinase. J Biol Chem 260: 10027-10031.
    • (1985) J Biol Chem , vol.260 , pp. 10027-10031
    • Ikebe, M.1    Hartshorne, D.J.2
  • 17
    • 0023927958 scopus 로고
    • Effects of phosphorylation of light chain residues threonine 18 and serine 19 on the properties and conformation of smooth muscle myosin
    • Ikebe M, Koretz J, Hartshorne DJ. 1988. Effects of phosphorylation of light chain residues threonine 18 and serine 19 on the properties and conformation of smooth muscle myosin. J Biol Chem 263: 6432-6437.
    • (1988) J Biol Chem , vol.263 , pp. 6432-6437
    • Ikebe, M.1    Koretz, J.2    Hartshorne, D.J.3
  • 18
    • 0026592482 scopus 로고
    • Diphosphorylation of platelet myosin by myosin light chain kinase
    • Itoh K, Hara T, Shibata N. 1992. Diphosphorylation of platelet myosin by myosin light chain kinase. Biochim Biophys Acta 1133: 286-292.
    • (1992) Biochim Biophys Acta , vol.1133 , pp. 286-292
    • Itoh, K.1    Hara, T.2    Shibata, N.3
  • 19
    • 34247560661 scopus 로고    scopus 로고
    • Novel therapies for microvascular permeability in sepsis
    • Jacobson JR, Garcia JG. 2007. Novel therapies for microvascular permeability in sepsis. Curr Drug Targets 8: 509-514.
    • (2007) Curr Drug Targets , vol.8 , pp. 509-514
    • Jacobson, J.R.1    Garcia, J.G.2
  • 20
    • 0035895901 scopus 로고    scopus 로고
    • Dedicated myosin light chain kinases with diverse cellular functions
    • Kamm KE, Stull JT. 2001. Dedicated myosin light chain kinases with diverse cellular functions. J Biol Chem 276: 4527-4530.
    • (2001) J Biol Chem , vol.276 , pp. 4527-4530
    • Kamm, K.E.1    Stull, J.T.2
  • 22
    • 77951697920 scopus 로고    scopus 로고
    • Regulation of endothelial permeability via paracellular and transcellular transport pathways
    • Komarova Y, Malik AB. 2010. Regulation of endothelial permeability via paracellular and transcellular transport pathways. Annu Rev Physiol 72: 463-493.
    • (2010) Annu Rev Physiol , vol.72 , pp. 463-493
    • Komarova, Y.1    Malik, A.B.2
  • 23
    • 24144444059 scopus 로고    scopus 로고
    • Epac1 regulates integrity of endothelial cell junctions through VE-cadherin
    • Kooistra MR, Corada M, Dejana E, Bos JL. 2005. Epac1 regulates integrity of endothelial cell junctions through VE-cadherin. FEBS Lett 579: 4966-4972.
    • (2005) FEBS Lett , vol.579 , pp. 4966-4972
    • Kooistra, M.R.1    Corada, M.2    Dejana, E.3    Bos, J.L.4
  • 25
    • 14244251637 scopus 로고    scopus 로고
    • The permeability-reducing effects of prostacyclin and inhibition of Rho kinase do not counteract endotoxin-induced increase in permeability in cat skeletal muscle
    • Lundblad C, Bentzer P, Grande PO. 2004. The permeability-reducing effects of prostacyclin and inhibition of Rho kinase do not counteract endotoxin-induced increase in permeability in cat skeletal muscle. Microvasc Res 68: 286-294.
    • (2004) Microvasc Res , vol.68 , pp. 286-294
    • Lundblad, C.1    Bentzer, P.2    Grande, P.O.3
  • 26
    • 0037901361 scopus 로고    scopus 로고
    • Management of respiratory dysfunction in patients with severe sepsis
    • In: Vincent J-L, Carlet J, Opal SM, editors. Boston Dordrecht London: Kluwer Academic Publishers.
    • Martin GS, Bernard GR. 2002. Management of respiratory dysfunction in patients with severe sepsis. In: Vincent J-L, Carlet J, Opal SM, editors. The sepsis text. Boston Dordrecht London: Kluwer Academic Publishers. pp 455-477.
    • (2002) The sepsis text , pp. 455-477
    • Martin, G.S.1    Bernard, G.R.2
  • 27
    • 0037451929 scopus 로고    scopus 로고
    • The epidemiology of sepsis in the United States from 1979 through 2000
    • Martin GS, Mannino DM, Eaton S, Moss M. 2003. The epidemiology of sepsis in the United States from 1979 through 2000. N Engl J Med 348: 1546-1554.
    • (2003) N Engl J Med , vol.348 , pp. 1546-1554
    • Martin, G.S.1    Mannino, D.M.2    Eaton, S.3    Moss, M.4
  • 28
    • 40849097955 scopus 로고    scopus 로고
    • Myosin phosphatase target subunit: Many roles in cell function
    • Matsumura F, Hartshorne DJ. 2008. Myosin phosphatase target subunit: Many roles in cell function. Biochem Biophys Res Commun 369: 149-156.
    • (2008) Biochem Biophys Res Commun , vol.369 , pp. 149-156
    • Matsumura, F.1    Hartshorne, D.J.2
  • 30
    • 61449149438 scopus 로고    scopus 로고
    • Activation of Rho kinase isoforms in lung endothelial cells during inflammation
    • Mong PY, Wang Q. 2009. Activation of Rho kinase isoforms in lung endothelial cells during inflammation. J Immunol 182: 2385-2394.
    • (2009) J Immunol , vol.182 , pp. 2385-2394
    • Mong, P.Y.1    Wang, Q.2
  • 31
    • 26244450671 scopus 로고    scopus 로고
    • Myosin light chain kinase is involved in lipopolysaccharide-induced disruption of colonic epithelial barrier and bacterial translocation in rats
    • Moriez R, Salvador-Cartier C, Theodorou V, Fioramonti J, Eutamene H, Bueno L. 2005. Myosin light chain kinase is involved in lipopolysaccharide-induced disruption of colonic epithelial barrier and bacterial translocation in rats. Am J Pathol 167: 1071-1079.
    • (2005) Am J Pathol , vol.167 , pp. 1071-1079
    • Moriez, R.1    Salvador-Cartier, C.2    Theodorou, V.3    Fioramonti, J.4    Eutamene, H.5    Bueno, L.6
  • 32
    • 48849116430 scopus 로고    scopus 로고
    • Pharmacological PKA inhibition: All may not be what it seems
    • re4.
    • Murray AJ. 2008. Pharmacological PKA inhibition: All may not be what it seems. Sci Signal 1: re4.
    • (2008) Sci Signal , vol.1
    • Murray, A.J.1
  • 34
    • 0021268721 scopus 로고
    • Phosphorylation of mammalian myosin light chain kinases by the catalytic subunit of cyclic AMP-dependent protein kinase and by cyclic GMP-dependent protein kinase
    • Nishikawa M, de Lanerolle P, Lincoln TM, Adelstein RS. 1984. Phosphorylation of mammalian myosin light chain kinases by the catalytic subunit of cyclic AMP-dependent protein kinase and by cyclic GMP-dependent protein kinase. J Biol Chem 259: 8429-8436.
    • (1984) J Biol Chem , vol.259 , pp. 8429-8436
    • Nishikawa, M.1    de Lanerolle, P.2    Lincoln, T.M.3    Adelstein, R.S.4
  • 35
    • 34547515353 scopus 로고    scopus 로고
    • The host response to endotoxin, antilipopolysaccharide strategies, and the management of severe sepsis
    • Opal SM. 2007. The host response to endotoxin, antilipopolysaccharide strategies, and the management of severe sepsis. Int J Med Microbiol 297: 365-377.
    • (2007) Int J Med Microbiol , vol.297 , pp. 365-377
    • Opal, S.M.1
  • 36
    • 0038172667 scopus 로고    scopus 로고
    • PKA inhibits RhoA activation: A protection mechanism against endothelial barrier dysfunction
    • Qiao J, Huang F, Lum H. 2003. PKA inhibits RhoA activation: A protection mechanism against endothelial barrier dysfunction. Am J Physiol Lung Cell Mol Physiol 284: L972-L980.
    • (2003) Am J Physiol Lung Cell Mol Physiol , vol.284
    • Qiao, J.1    Huang, F.2    Lum, H.3
  • 37
    • 34548491399 scopus 로고    scopus 로고
    • Rho/Rho-associated kinase-II signaling mediates disassembly of epithelial apical junctions
    • Samarin SN, Ivanov AI, Flatau G, Parkos CA, Nusrat A. 2007. Rho/Rho-associated kinase-II signaling mediates disassembly of epithelial apical junctions. Mol Biol Cell 18: 3429-3439.
    • (2007) Mol Biol Cell , vol.18 , pp. 3429-3439
    • Samarin, S.N.1    Ivanov, A.I.2    Flatau, G.3    Parkos, C.A.4    Nusrat, A.5
  • 38
    • 67650492748 scopus 로고    scopus 로고
    • Lipopolysaccharide-induced endothelial barrier breakdown is cyclic adenosine monophosphate dependent in vivo and in vitro
    • Schlegel N, Baumer Y, Drenckhahn D, Waschke J. 2009. Lipopolysaccharide-induced endothelial barrier breakdown is cyclic adenosine monophosphate dependent in vivo and in vitro. Crit Care Med 37: 1735-1743.
    • (2009) Crit Care Med , vol.37 , pp. 1735-1743
    • Schlegel, N.1    Baumer, Y.2    Drenckhahn, D.3    Waschke, J.4
  • 40
    • 0037004888 scopus 로고    scopus 로고
    • Spatial localization of mono-and diphosphorylated myosin II regulatory light chain at the leading edge of motile HeLa cells
    • Uchimura T, Fumoto K, Yamamoto Y, Ueda K, Hosoya H. 2002. Spatial localization of mono-and diphosphorylated myosin II regulatory light chain at the leading edge of motile HeLa cells. Cell Struct Funct 27: 479-486.
    • (2002) Cell Struct Funct , vol.27 , pp. 479-486
    • Uchimura, T.1    Fumoto, K.2    Yamamoto, Y.3    Ueda, K.4    Hosoya, H.5
  • 42
    • 0031722950 scopus 로고    scopus 로고
    • Role of Ca2+/calmodulin-dependent phosphatase 2B in thrombin-induced endothelial cell contractile responses
    • Verin AD, Cooke C, Herenyiova M, Patterson CE, Garcia JG. 1998a. Role of Ca2+/calmodulin-dependent phosphatase 2B in thrombin-induced endothelial cell contractile responses. Am J Physiol 275: L788-L799.
    • (1998) Am J Physiol , vol.275
    • Verin, A.D.1    Cooke, C.2    Herenyiova, M.3    Patterson, C.E.4    Garcia, J.G.5
  • 46
    • 0034604129 scopus 로고    scopus 로고
    • The acute respiratory distress syndrome
    • Ware LB, Matthay MA. 2000. The acute respiratory distress syndrome. N Engl J Med 342: 1334-1349.
    • (2000) N Engl J Med , vol.342 , pp. 1334-1349
    • Ware, L.B.1    Matthay, M.A.2
  • 47
    • 33846815057 scopus 로고    scopus 로고
    • Regulation of myosin II dynamics by phosphorylation and dephosphorylation of its light chain in epithelial cells
    • Watanabe T, Hosoya H, Yonemura S. 2007. Regulation of myosin II dynamics by phosphorylation and dephosphorylation of its light chain in epithelial cells. Mol Biol Cell 18: 605-616.
    • (2007) Mol Biol Cell , vol.18 , pp. 605-616
    • Watanabe, T.1    Hosoya, H.2    Yonemura, S.3


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