Nicotinic acetylcholine receptor agonists attenuate septic acute kidney injury in mice by suppressing inflammation and proteasome activity

PLoS ONE

Volumn 7, Issue 5, 2012, Pages

  Chatterjee, Prodyot K ^a   Yeboah, Michael M ^b   Dowling, Oonagh ^a,c   Xue, Xiangying ^a   Powell, Saul R ^a   Al Abed, Yousef ^a   Metz, Christine N ^a  

^a FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c Northwell Health   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 (2,4 DIMETHOXYBENZYLIDENE)ANABASEINE; 3 (4 METHYLPHENYLSULFONYL) 2 PROPENENITRILE; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; BUNGAROTOXIN RECEPTOR; GAMMA INTERFERON INDUCIBLE PROTEIN 10; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; MONOCYTE CHEMOTACTIC PROTEIN 1; NICOTINE; NICOTINIC AGENT; NICOTINIC RECEPTOR ALPHA4; NICOTINIC RECEPTOR BETA2; PROTEASOME; TUMOR NECROSIS FACTOR ALPHA; 3-(2,4-DIMETHOXYBENZYLIDENE)ANABASEINE; BENZYLIDENE DERIVATIVE; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR BLOCKING AGENT; PROTECTIVE AGENT; PYRIDINE DERIVATIVE;

ACUTE KIDNEY FAILURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE MODEL; FEMALE; HUMAN; HUMAN CELL; INHIBITION KINETICS; KIDNEY CELL; MOUSE; NEPHRITIS; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PROTEIN DEGRADATION; PROTEIN EXPRESSION; RENAL PROTECTION; SEPSIS; ANIMAL; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; INFLAMMATION; METABOLISM;

MUS;

ACUTE KIDNEY INJURY; ANIMALS; BENZYLIDENE COMPOUNDS; INFLAMMATION; LIPOPOLYSACCHARIDES; MICE; NICOTINIC ANTAGONISTS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTECTIVE AGENTS; PYRIDINES; RECEPTORS, NICOTINIC;

EID: 84860605957     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0035361     Document Type: Article

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