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Volumn 19, Issue 32, 2013, Pages 5238-5249

DNA methylation in inflammatory bowel disease and beyond

Author keywords

Colitis; Crohn's disease; DNA methyltransferase; Epi therapy; Intestinal inflammation

Indexed keywords

ALKALOID DERIVATIVE; AMINOSALICYLIC ACID; AZATHIOPRINE; B LYMPHOCYTE INDUCED MATURATION PROTEIN 1; CASPASE RECRUITMENT DOMAIN PROTEIN 15; CATHELICIDIN ANTIMICROBIAL PEPTIDE LL 37; CXCL16 CHEMOKINE; CYCLOSPORIN; DNA METHYLTRANSFERASE; FOLINIC ACID; INTERLEUKIN 12P40; METHOTREXATE; TOLL LIKE RECEPTOR 9; TRANSFORMING GROWTH FACTOR; TUMOR NECROSIS FACTOR ALPHA ANTIBODY; UNCLASSIFIED DRUG; W8; BACTERIAL DNA; GASTROINTESTINAL AGENT;

EID: 84883041993     PISSN: 10079327     EISSN: 22192840     Source Type: Journal    
DOI: 10.3748/wjg.v19.i32.5238     Document Type: Review
Times cited : (34)

References (81)
  • 1
    • 0026432216 scopus 로고
    • Inflammatory bowel disease (1)
    • [PMID: 1881418 DOI: 10.1056/ NEJM199109263251306]
    • Podolsky DK. Inflammatory bowel disease (1). N Engl J Med 1991; 325: 928-937 [PMID: 1881418 DOI: 10.1056/ NEJM199109263251306]
    • (1991) N Engl J Med , vol.325 , pp. 928-937
    • Podolsky, D.K.1
  • 2
    • 0035865012 scopus 로고    scopus 로고
    • Cancer risk in patients with inflammatory bowel disease: A population-based study
    • [PMID: 11241255]
    • Bernstein CN, Blanchard JF, Kliewer E, Wajda A. Cancer risk in patients with inflammatory bowel disease: a population-based study. Cancer 2001; 91: 854-862 [PMID: 11241255]
    • (2001) Cancer , vol.91 , pp. 854-862
    • Bernstein, C.N.1    Blanchard, J.F.2    Kliewer, E.3    Wajda, A.4
  • 7
    • 0020489781 scopus 로고
    • Amount and distribution of 5-methylcytosine in human DNA from different types of tissues of cells
    • [PMID: 7079182]
    • Ehrlich M, Gama-Sosa MA, Huang LH, Midgett RM, Kuo KC, McCune RA, Gehrke C. Amount and distribution of 5-methylcytosine in human DNA from different types of tissues of cells. Nucleic Acids Res 1982; 10: 2709-2721 [PMID: 7079182]
    • (1982) Nucleic Acids Res , vol.10 , pp. 2709-2721
    • Ehrlich, M.1    Gama-Sosa, M.A.2    Huang, L.H.3    Midgett, R.M.4    Kuo, K.C.5    McCune, R.A.6    Gehrke, C.7
  • 8
    • 0036144048 scopus 로고    scopus 로고
    • DNA methylation patterns and epigenetic memory
    • [PMID: 11782440 DOI: 10.1101/ gad.947102]
    • Bird A. DNA methylation patterns and epigenetic memory. Genes Dev 2002; 16: 6-21 [PMID: 11782440 DOI: 10.1101/ gad.947102]
    • (2002) Genes Dev , vol.16 , pp. 6-21
    • Bird, A.1
  • 9
    • 77951188458 scopus 로고    scopus 로고
    • Upregulation of DNA methyltransferase-mediated gene silencing, anchorage-independent growth, and migration of colon cancer cells by interleukin-6
    • [PMID: 20354000 DOI: 10.1158/1541-7786.MCR-09-0496]
    • Foran E, Garrity-Park MM, Mureau C, Newell J, Smyrk TC, Limburg PJ, Egan LJ. Upregulation of DNA methyltransferase-mediated gene silencing, anchorage-independent growth, and migration of colon cancer cells by interleukin-6. Mol Cancer Res 2010; 8: 471-481 [PMID: 20354000 DOI: 10.1158/1541-7786.MCR-09-0496]
    • (2010) Mol Cancer Res , vol.8 , pp. 471-481
    • Foran, E.1    Garrity-Park, M.M.2    Mureau, C.3    Newell, J.4    Smyrk, T.C.5    Limburg, P.J.6    Egan, L.J.7
  • 10
    • 77954237282 scopus 로고    scopus 로고
    • Increased expression of DNA methyltransferase-1 in non-neoplastic epithelium helps predict colorectal neoplasia risk in ulcerative colitis
    • [PMID: 20588031 DOI: 10.1159/000311064]
    • Fujii S, Katake Y, Tanaka H. Increased expression of DNA methyltransferase-1 in non-neoplastic epithelium helps predict colorectal neoplasia risk in ulcerative colitis. Digestion 2010; 82: 179-186 [PMID: 20588031 DOI: 10.1159/000311064]
    • (2010) Digestion , vol.82 , pp. 179-186
    • Fujii, S.1    Katake, Y.2    Tanaka, H.3
  • 11
    • 80051539323 scopus 로고    scopus 로고
    • DNA methylation of colon mucosa in ulcerative colitis patients: Correlation with inflammatory status
    • [PMID; 21830274 DOI: 10.1002/ibd.21573]
    • Saito S, Kato J, Hiraoka S, Horii J, Suzuki H, Higashi R, Kaji E, Kondo Y, Yamamoto K. DNA methylation of colon mucosa in ulcerative colitis patients: correlation with inflammatory status. Inflamm Bowel Dis 2011; 17: 1955-1965 [PMID; 21830274 DOI: 10.1002/ibd.21573]
    • (2011) Inflamm Bowel Dis , vol.17 , pp. 1955-1965
    • Saito, S.1    Kato, J.2    Hiraoka, S.3    Horii, J.4    Suzuki, H.5    Higashi, R.6    Kaji, E.7    Kondo, Y.8    Yamamoto, K.9
  • 12
    • 33746651038 scopus 로고    scopus 로고
    • STAT3 induces transcription of the DNA methyltransferase 1 gene (DNMT1) in malignant T lymphocytes
    • [PMID: 16861352 DOI: 10.1182/blood-2005-08-007377]
    • Zhang Q, Wang HY, Woetmann A, Raghunath PN, Odum N, Wasik MA. STAT3 induces transcription of the DNA methyltransferase 1 gene (DNMT1) in malignant T lymphocytes. Blood 2006; 108: 1058-1064 [PMID: 16861352 DOI: 10.1182/blood-2005-08-007377]
    • (2006) Blood , vol.108 , pp. 1058-1064
    • Zhang, Q.1    Wang, H.Y.2    Woetmann, A.3    Raghunath, P.N.4    Odum, N.5    Wasik, M.A.6
  • 14
    • 84867322245 scopus 로고    scopus 로고
    • IL-6-induced DNMT1 activity mediates SOCS3 promoter hypermethylation in ulcerative colitisrelated colorectal cancer
    • [PMID: 22739025 DOI: 10.1093/carcin/bgs214]
    • Li Y, Deuring J, Peppelenbosch MP, Kuipers EJ, de Haar C, van der Woude CJ. IL-6-induced DNMT1 activity mediates SOCS3 promoter hypermethylation in ulcerative colitisrelated colorectal cancer. Carcinogenesis 2012; 33: 1889-1896 [PMID: 22739025 DOI: 10.1093/carcin/bgs214]
    • (2012) Carcinogenesis , vol.33 , pp. 1889-1896
    • Li, Y.1    Deuring, J.2    Peppelenbosch, M.P.3    Kuipers, E.J.4    de Haar, C.5    van der Woude, C.J.6
  • 17
    • 33745753087 scopus 로고    scopus 로고
    • Inhibition of IFN-gamma transcription by site-specific methylation during T helper cell development
    • [PMID: 16724115 DOI: 10.1038/ sj.emboj.7601148]
    • Jones B, Chen J. Inhibition of IFN-gamma transcription by site-specific methylation during T helper cell development. EMBO J 2006; 25: 2443-2452 [PMID: 16724115 DOI: 10.1038/ sj.emboj.7601148]
    • (2006) EMBO J , vol.25 , pp. 2443-2452
    • Jones, B.1    Chen, J.2
  • 18
    • 78650102072 scopus 로고    scopus 로고
    • Distinct IFNG methylation in a subset of ulcerative colitis patients based on reactivity to microbial antigens
    • [PMID; 20848535 DOI: 10.1002/ibd.21352]
    • Gonsky R, Deem RL, Landers CJ, Derkowski CA, Berel D, McGovern DP, Targan SR. Distinct IFNG methylation in a subset of ulcerative colitis patients based on reactivity to microbial antigens. Inflamm Bowel Dis 2011; 17: 171-178 [PMID; 20848535 DOI: 10.1002/ibd.21352]
    • (2011) Inflamm Bowel Dis , vol.17 , pp. 171-178
    • Gonsky, R.1    Deem, R.L.2    Landers, C.J.3    Derkowski, C.A.4    Berel, D.5    McGovern, D.P.6    Targan, S.R.7
  • 19
    • 57749094930 scopus 로고    scopus 로고
    • G9a and HP1 couple histone and DNA methylation to TNFalpha transcription silencing during endotoxin tolerance
    • [PMID: 18809684 DOI: 10.1074/jbc.M803446200]
    • El Gazzar M, Yoza BK, Chen X, Hu J, Hawkins GA, McCall CE. G9a and HP1 couple histone and DNA methylation to TNFalpha transcription silencing during endotoxin tolerance. J Biol Chem 2008; 283: 32198-32208 [PMID: 18809684 DOI: 10.1074/jbc.M803446200]
    • (2008) J Biol Chem , vol.283 , pp. 32198-32208
    • El Gazzar, M.1    Yoza, B.K.2    Chen, X.3    Hu, J.4    Hawkins, G.A.5    McCall, C.E.6
  • 20
    • 80052933429 scopus 로고    scopus 로고
    • DNA demethylation dynamics
    • [PMID: 21925312 DOI: 10.1016/j.cell.2011.08.042]
    • Bhutani N, Burns DM, Blau HM. DNA demethylation dynamics. Cell 2011; 146: 866-872 [PMID: 21925312 DOI: 10.1016/j.cell.2011.08.042]
    • (2011) Cell , vol.146 , pp. 866-872
    • Bhutani, N.1    Burns, D.M.2    Blau, H.M.3
  • 22
    • 84872245173 scopus 로고    scopus 로고
    • TET1 is a negative transcriptional regulator of IL-1β in the THP-1 cell line
    • [PMID: 23328087 DOI: 10.1016/ j.molimm.2012.12.014]
    • Neves-Costa A, Moita LF. TET1 is a negative transcriptional regulator of IL-1β in the THP-1 cell line. Mol Immunol 2013; 54: 264-270 [PMID: 23328087 DOI: 10.1016/ j.molimm.2012.12.014]
    • (2013) Mol Immunol , vol.54 , pp. 264-270
    • Neves-Costa, A.1    Moita, L.F.2
  • 24
    • 10644282845 scopus 로고    scopus 로고
    • Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: Implications for epigenetic reprogramming
    • [PMID: 15448152 DOI: 10.1074/ jbc.M407695200]
    • Morgan HD, Dean W, Coker HA, Reik W, Petersen-Mahrt SK. Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: implications for epigenetic reprogramming. J Biol Chem 2004; 279: 52353-52360 [PMID: 15448152 DOI: 10.1074/ jbc.M407695200]
    • (2004) J Biol Chem , vol.279 , pp. 52353-52360
    • Morgan, H.D.1    Dean, W.2    Coker, H.A.3    Reik, W.4    Petersen-Mahrt, S.K.5
  • 25
    • 77249148019 scopus 로고    scopus 로고
    • Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency
    • [PMID: 20098412]
    • Popp C, Dean W, Feng S, Cokus SJ, Andrews S, Pellegrini M, Jacobsen SE, Reik W. Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency. Nature 2010; 463: 1101-1105 [PMID: 20098412]
    • (2010) Nature , vol.463 , pp. 1101-1105
    • Popp, C.1    Dean, W.2    Feng, S.3    Cokus, S.J.4    Andrews, S.5    Pellegrini, M.6    Jacobsen, S.E.7    Reik, W.8
  • 26
    • 34249807921 scopus 로고    scopus 로고
    • DNA deamination in immunity: AID in the context of its APOBEC relatives
    • [PMID: 17560271 DOI: 10.1016/S0065-2776(06)94002-4]
    • Conticello SG, Langlois MA, Yang Z, Neuberger MS. DNA deamination in immunity: AID in the context of its APOBEC relatives. Adv Immunol 2007; 94: 37-73 [PMID: 17560271 DOI: 10.1016/S0065-2776(06)94002-4]
    • (2007) Adv Immunol , vol.94 , pp. 37-73
    • Conticello, S.G.1    Langlois, M.A.2    Yang, Z.3    Neuberger, M.S.4
  • 27
    • 0034268780 scopus 로고    scopus 로고
    • Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme
    • [PMID: 11007474]
    • Muramatsu M, Kinoshita K, Fagarasan S, Yamada S, Shinkai Y, Honjo T. Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme. Cell 2000; 102: 553-563 [PMID: 11007474]
    • (2000) Cell , vol.102 , pp. 553-563
    • Muramatsu, M.1    Kinoshita, K.2    Fagarasan, S.3    Yamada, S.4    Shinkai, Y.5    Honjo, T.6
  • 28
    • 0037019315 scopus 로고    scopus 로고
    • AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification
    • [PMID: 12097915]
    • Petersen-Mahrt SK, Harris RS, Neuberger MS. AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification. Nature 2002; 418: 99-103 [PMID: 12097915]
    • (2002) Nature , vol.418 , pp. 99-103
    • Petersen-Mahrt, S.K.1    Harris, R.S.2    Neuberger, M.S.3
  • 29
    • 0038074420 scopus 로고    scopus 로고
    • The versatile thymine DNA-glycosylase: A comparative characterization of the human, Drosophila and fission yeast orthologs
    • [PMID: 12711670]
    • Hardeland U, Bentele M, Jiricny J, Schär P. The versatile thymine DNA-glycosylase: a comparative characterization of the human, Drosophila and fission yeast orthologs. Nucleic Acids Res 2003; 31: 2261-2271 [PMID: 12711670]
    • (2003) Nucleic Acids Res , vol.31 , pp. 2261-2271
    • Hardeland, U.1    Bentele, M.2    Jiricny, J.3    Schär, P.4
  • 30
    • 51249087746 scopus 로고    scopus 로고
    • Activation-induced cytidine deaminase links between inflammation and the development of colitis-associated colorectal cancers
    • [PMID: 18691581 DOI: 10.1053/ j.gastro.2008.06.091]
    • Endo Y, Marusawa H, Kou T, Nakase H, Fujii S, Fujimori T, Kinoshita K, Honjo T, Chiba T. Activation-induced cytidine deaminase links between inflammation and the development of colitis-associated colorectal cancers. Gastroenterology 2008; 135: 889-898, 898. e1-3 [PMID: 18691581 DOI: 10.1053/ j.gastro.2008.06.091]
    • (2008) Gastroenterology , vol.135
    • Endo, Y.1    Marusawa, H.2    Kou, T.3    Nakase, H.4    Fujii, S.5    Fujimori, T.6    Kinoshita, K.7    Honjo, T.8    Chiba, T.9
  • 31
    • 84859426818 scopus 로고    scopus 로고
    • Targeting activationinduced cytidine deaminase prevents colon cancer development despite persistent colonic inflammation
    • [PMID: 21841819 DOI: 10.1038/ onc.2011.352]
    • Takai A, Marusawa H, Minaki Y, Watanabe T, Nakase H, Kinoshita K, Tsujimoto G, Chiba T. Targeting activationinduced cytidine deaminase prevents colon cancer development despite persistent colonic inflammation. Oncogene 2012; 31: 1733-1742 [PMID: 21841819 DOI: 10.1038/ onc.2011.352]
    • (2012) Oncogene , vol.31 , pp. 1733-1742
    • Takai, A.1    Marusawa, H.2    Minaki, Y.3    Watanabe, T.4    Nakase, H.5    Kinoshita, K.6    Tsujimoto, G.7    Chiba, T.8
  • 34
    • 84655164284 scopus 로고    scopus 로고
    • De novo DNA methylation: A germ cell perspective
    • [PMID; 22019337 DOI: 10.1016/j.tig.2011.09.004]
    • Smallwood SA, Kelsey G. De novo DNA methylation: a germ cell perspective. Trends Genet 2012; 28: 33-42 [PMID; 22019337 DOI: 10.1016/j.tig.2011.09.004]
    • (2012) Trends Genet , vol.28 , pp. 33-42
    • Smallwood, S.A.1    Kelsey, G.2
  • 35
    • 0030784426 scopus 로고    scopus 로고
    • Differences in risk of Crohn's disease in offspring of mothers and fathers with inflammatory bowel disease
    • [PMID: 9399762]
    • Akolkar PN, Gulwani-Akolkar B, Heresbach D, Lin XY, Fisher S, Katz S, Silver J. Differences in risk of Crohn's disease in offspring of mothers and fathers with inflammatory bowel disease. Am J Gastroenterol 1997; 92: 2241-2244 [PMID: 9399762]
    • (1997) Am J Gastroenterol , vol.92 , pp. 2241-2244
    • Akolkar, P.N.1    Gulwani-Akolkar, B.2    Heresbach, D.3    Lin, X.Y.4    Fisher, S.5    Katz, S.6    Silver, J.7
  • 37
    • 79954519615 scopus 로고    scopus 로고
    • Maternal methyl-donor supplementation induces prolonged murine offspring colitis susceptibility in association with mucosal epigenetic and microbiomic changes
    • [PMID: 21296867 DOI: 10.1093/hmg/ddr044]
    • Schaible TD, Harris RA, Dowd SE, Smith CW, Kellermayer R. Maternal methyl-donor supplementation induces prolonged murine offspring colitis susceptibility in association with mucosal epigenetic and microbiomic changes. Hum Mol Genet 2011; 20: 1687-1696 [PMID: 21296867 DOI: 10.1093/hmg/ddr044]
    • (2011) Hum Mol Genet , vol.20 , pp. 1687-1696
    • Schaible, T.D.1    Harris, R.A.2    Dowd, S.E.3    Smith, C.W.4    Kellermayer, R.5
  • 38
    • 34249903855 scopus 로고    scopus 로고
    • Oxidative DNA damage and antioxidant activity in patients with inflammatory bowel disease
    • [PMID: 17393334 DOI: 10.1007/s10620-006-9386-8]
    • Dincer Y, Erzin Y, Himmetoglu S, Gunes KN, Bal K, Akcay T. Oxidative DNA damage and antioxidant activity in patients with inflammatory bowel disease. Dig Dis Sci 2007; 52: 1636-1641 [PMID: 17393334 DOI: 10.1007/s10620-006-9386-8]
    • (2007) Dig Dis Sci , vol.52 , pp. 1636-1641
    • Dincer, Y.1    Erzin, Y.2    Himmetoglu, S.3    Gunes, K.N.4    Bal, K.5    Akcay, T.6
  • 39
    • 46749095883 scopus 로고    scopus 로고
    • Oxidative stress in ulcerative colitis-associated carcinogenesis
    • [PMID: 18571874 DOI: 10.1016/j.prp.2008.04.011]
    • Roessner A, Kuester D, Malfertheiner P, Schneider-Stock R. Oxidative stress in ulcerative colitis-associated carcinogenesis. Pathol Res Pract 2008; 204: 511-524 [PMID: 18571874 DOI: 10.1016/j.prp.2008.04.011]
    • (2008) Pathol Res Pract , vol.204 , pp. 511-524
    • Roessner, A.1    Kuester, D.2    Malfertheiner, P.3    Schneider-Stock, R.4
  • 41
    • 34247273521 scopus 로고    scopus 로고
    • Rare CpG island methylator phenotype in ulcerative colitisassociated neoplasias
    • [PMID: 17408633 DOI: 10.1053/j.gastro.2007.01.035]
    • Konishi K, Shen L, Wang S, Meltzer SJ, Harpaz N, Issa JP. Rare CpG island methylator phenotype in ulcerative colitisassociated neoplasias. Gastroenterology 2007; 132: 1254-1260 [PMID: 17408633 DOI: 10.1053/j.gastro.2007.01.035]
    • (2007) Gastroenterology , vol.132 , pp. 1254-1260
    • Konishi, K.1    Shen, L.2    Wang, S.3    Meltzer, S.J.4    Harpaz, N.5    Issa, J.P.6
  • 42
    • 67649231565 scopus 로고    scopus 로고
    • Colitis-associated variant of TLR2 causes impaired mucosal repair because of TFF3 deficiency
    • [PMID: 19303021 DOI: 10.1053/j.gastro.2009.03.007]
    • Podolsky DK, Gerken G, Eyking A, Cario E. Colitis-associated variant of TLR2 causes impaired mucosal repair because of TFF3 deficiency. Gastroenterology 2009; 137: 209-220 [PMID: 19303021 DOI: 10.1053/j.gastro.2009.03.007]
    • (2009) Gastroenterology , vol.137 , pp. 209-220
    • Podolsky, D.K.1    Gerken, G.2    Eyking, A.3    Cario, E.4
  • 43
    • 84878254278 scopus 로고    scopus 로고
    • Involvement of the NOcGMP-K(ATP) channel pathway in the mesenteric lymphatic pump dysfunction observed in the guinea pig model of TNBS-induced ileitis
    • [PMID: 23275612 DOI: 10.1152/ajpgi. 00392.2012]
    • Mathias R, von der Weid PY. Involvement of the NOcGMP-K(ATP) channel pathway in the mesenteric lymphatic pump dysfunction observed in the guinea pig model of TNBS-induced ileitis. Am J Physiol Gastrointest Liver Physiol 2013; 304: G623-G634 [PMID: 23275612 DOI: 10.1152/ajpgi. 00392.2012]
    • (2013) Am J Physiol Gastrointest Liver Physiol , vol.304
    • Mathias, R.1    von der Weid, P.Y.2
  • 44
    • 84871595863 scopus 로고    scopus 로고
    • Hydrogen sulfide as an allosteric modulator of ATP-sensitive potassium channels in colonic inflammation
    • [PMID: 23115325 DOI: 10.1124/mol.112.081596]
    • Gade AR, Kang M, Akbarali HI. Hydrogen sulfide as an allosteric modulator of ATP-sensitive potassium channels in colonic inflammation. Mol Pharmacol 2013; 83: 294-306 [PMID: 23115325 DOI: 10.1124/mol.112.081596]
    • (2013) Mol Pharmacol , vol.83 , pp. 294-306
    • Gade, A.R.1    Kang, M.2    Akbarali, H.I.3
  • 45
    • 0041837509 scopus 로고    scopus 로고
    • Trefoil factors: Initiators of mucosal healing
    • [PMID; 14506475 DOI: 10.1038/nrm1203]
    • Taupin D, Podolsky DK. Trefoil factors: initiators of mucosal healing. Nat Rev Mol Cell Biol 2003; 4: 721-732 [PMID; 14506475 DOI: 10.1038/nrm1203]
    • (2003) Nat Rev Mol Cell Biol , vol.4 , pp. 721-732
    • Taupin, D.1    Podolsky, D.K.2
  • 46
    • 0029828745 scopus 로고    scopus 로고
    • Impaired defense of intestinal mucosa in mice lacking intestinal trefoil factor
    • [PMID: 8824194 DOI: 10.1126/science.274.5285.262]
    • Mashimo H, Wu DC, Podolsky DK, Fishman MC. Impaired defense of intestinal mucosa in mice lacking intestinal trefoil factor. Science 1996; 274: 262-265 [PMID: 8824194 DOI: 10.1126/science.274.5285.262]
    • (1996) Science , vol.274 , pp. 262-265
    • Mashimo, H.1    Wu, D.C.2    Podolsky, D.K.3    Fishman, M.C.4
  • 47
    • 0035821249 scopus 로고    scopus 로고
    • Hypoxiainducible factor 1-dependent induction of intestinal trefoil factor protects barrier function during hypoxia
    • [PMID: 11342587]
    • Furuta GT, Turner JR, Taylor CT, Hershberg RM, Comerford K, Narravula S, Podolsky DK, Colgan SP. Hypoxiainducible factor 1-dependent induction of intestinal trefoil factor protects barrier function during hypoxia. J Exp Med 2001; 193: 1027-1034 [PMID: 11342587]
    • (2001) J Exp Med , vol.193 , pp. 1027-1034
    • Furuta, G.T.1    Turner, J.R.2    Taylor, C.T.3    Hershberg, R.M.4    Comerford, K.5    Narravula, S.6    Podolsky, D.K.7    Colgan, S.P.8
  • 48
    • 1542287384 scopus 로고    scopus 로고
    • Chemotherapy-and radiotherapyinduced intestinal damage is regulated by intestinal trefoil factor
    • [PMID: 14988834 DOI: 10.1053/j.gastro.2003.12.004]
    • Beck PL, Wong JF, Li Y, Swaminathan S, Xavier RJ, Devaney KL, Podolsky DK. Chemotherapy-and radiotherapyinduced intestinal damage is regulated by intestinal trefoil factor. Gastroenterology 2004; 126: 796-808 [PMID: 14988834 DOI: 10.1053/j.gastro.2003.12.004]
    • (2004) Gastroenterology , vol.126 , pp. 796-808
    • Beck, P.L.1    Wong, J.F.2    Li, Y.3    Swaminathan, S.4    Xavier, R.J.5    Devaney, K.L.6    Podolsky, D.K.7
  • 49
    • 67651001726 scopus 로고    scopus 로고
    • En-dogenous and exogenous hydrogen sulfide promotes resolution of colitis in rats
    • [PMID: 19375422 DOI: 10.1053/j.gastro.2009.04.012]
    • Wallace JL, Vong L, McKnight W, Dicay M, Martin GR. En-dogenous and exogenous hydrogen sulfide promotes resolution of colitis in rats. Gastroenterology 2009; 137: 569-78, 578. e1 [PMID: 19375422 DOI: 10.1053/j.gastro.2009.04.012]
    • (2009) Gastroenterology , vol.137
    • Wallace, J.L.1    Vong, L.2    McKnight, W.3    Dicay, M.4    Martin, G.R.5
  • 51
    • 0035871715 scopus 로고    scopus 로고
    • Expression cloning of the STRL33/BONZO/TYMSTRligand reveals elements of CC, CXC, and CX3C chemokines
    • [PMID: 11290797]
    • Wilbanks A, Zondlo SC, Murphy K, Mak S, Soler D, Langdon P, Andrew DP, Wu L, Briskin M. Expression cloning of the STRL33/BONZO/TYMSTRligand reveals elements of CC, CXC, and CX3C chemokines. J Immunol 2001; 166: 5145-5154 [PMID: 11290797]
    • (2001) J Immunol , vol.166 , pp. 5145-5154
    • Wilbanks, A.1    Zondlo, S.C.2    Murphy, K.3    Mak, S.4    Soler, D.5    Langdon, P.6    Andrew, D.P.7    Wu, L.8    Briskin, M.9
  • 53
    • 26844454484 scopus 로고    scopus 로고
    • Pathogenic role of the CXCL16-CXCR6 pathway in rheumatoid arthritis
    • [PMID: 16200580 DOI: 10.1002/art.21301]
    • Nanki T, Shimaoka T, Hayashida K, Taniguchi K, Yonehara S, Miyasaka N. Pathogenic role of the CXCL16-CXCR6 pathway in rheumatoid arthritis. Arthritis Rheum 2005; 52: 3004-3014 [PMID: 16200580 DOI: 10.1002/art.21301]
    • (2005) Arthritis Rheum , vol.52 , pp. 3004-3014
    • Nanki, T.1    Shimaoka, T.2    Hayashida, K.3    Taniguchi, K.4    Yonehara, S.5    Miyasaka, N.6
  • 55
    • 78249281655 scopus 로고    scopus 로고
    • Expression and regulation of the chemokine CXCL16 in Crohn's disease and models of intestinal inflammation
    • [PMID: 20848509 DOI: 10.1002/ibd.21306]
    • Diegelmann J, Seiderer J, Niess JH, Haller D, Göke B, Reinecker HC, Brand S. Expression and regulation of the chemokine CXCL16 in Crohn's disease and models of intestinal inflammation. Inflamm Bowel Dis 2010; 16: 1871-1881 [PMID: 20848509 DOI: 10.1002/ibd.21306]
    • (2010) Inflamm Bowel Dis , vol.16 , pp. 1871-1881
    • Diegelmann, J.1    Seiderer, J.2    Niess, J.H.3    Haller, D.4    Göke, B.5    Reinecker, H.C.6    Brand, S.7
  • 57
    • 84871770219 scopus 로고    scopus 로고
    • Targeting aberrant colon cancer-specific DNA methylation with lipoteichoic acid-deficient Lactobacillus acidophilus
    • [PMID: 23137966 DOI: 10.4161/ gmic.22822]
    • Lightfoot YL, Yang T, Sahay B, Mohamadzadeh M. Targeting aberrant colon cancer-specific DNA methylation with lipoteichoic acid-deficient Lactobacillus acidophilus. Gut Microbes 2013; 4: 84-88 [PMID: 23137966 DOI: 10.4161/ gmic.22822]
    • (2013) Gut Microbes , vol.4 , pp. 84-88
    • Lightfoot, Y.L.1    Yang, T.2    Sahay, B.3    Mohamadzadeh, M.4
  • 61
    • 0036316394 scopus 로고    scopus 로고
    • CpG motifs of bacterial DNA exacerbate colitis of dextran sulfate sodium-treated mice
    • [PMID: 12115630 DOI: 10.1002/1521-4141(200207) 32]
    • Obermeier F, Dunger N, Deml L, Herfarth H, Schölmerich J, Falk W. CpG motifs of bacterial DNA exacerbate colitis of dextran sulfate sodium-treated mice. Eur J Immunol 2002; 32: 2084-2092 [PMID: 12115630 DOI: 10.1002/1521-4141(200207) 32]
    • (2002) Eur J Immunol , vol.32 , pp. 2084-2092
    • Obermeier, F.1    Dunger, N.2    Deml, L.3    Herfarth, H.4    Schölmerich, J.5    Falk, W.6
  • 62
    • 70149090387 scopus 로고    scopus 로고
    • Higher activation of TLR9 in plasmacytoid dendritic cells by microbial DNA compared with self-DNA based on CpG-specific recognition of phosphodiester DNA
    • [PMID: 19620253 DOI: 10.1189/jlb.0509314]
    • Coch C, Busch N, Wimmenauer V, Hartmann E, Janke M, Abdel-Mottaleb MM, Lamprecht A, Ludwig J, Barchet W, Schlee M, Hartmann G. Higher activation of TLR9 in plasmacytoid dendritic cells by microbial DNA compared with self-DNA based on CpG-specific recognition of phosphodiester DNA. J Leukoc Biol 2009; 86: 663-670 [PMID: 19620253 DOI: 10.1189/jlb.0509314]
    • (2009) J Leukoc Biol , vol.86 , pp. 663-670
    • Coch, C.1    Busch, N.2    Wimmenauer, V.3    Hartmann, E.4    Janke, M.5    Abdel-Mottaleb, M.M.6    Lamprecht, A.7    Ludwig, J.8    Barchet, W.9    Schlee, M.10    Hartmann, G.11
  • 67
    • 84859795659 scopus 로고    scopus 로고
    • Genome-wide methylation profiling in Crohn's disease identifies altered epigenetic regulation of key host defense mechanisms including the Th17 pathway
    • [PMID: 22021194 DOI: 10.1002/ibd.21912]
    • Nimmo ER, Prendergast JG, Aldhous MC, Kennedy NA, Henderson P, Drummond HE, Ramsahoye BH, Wilson DC, Semple CA, Satsangi J. Genome-wide methylation profiling in Crohn's disease identifies altered epigenetic regulation of key host defense mechanisms including the Th17 pathway. Inflamm Bowel Dis 2012; 18: 889-899 [PMID: 22021194 DOI: 10.1002/ibd.21912]
    • (2012) Inflamm Bowel Dis , vol.18 , pp. 889-899
    • Nimmo, E.R.1    Prendergast, J.G.2    Aldhous, M.C.3    Kennedy, N.A.4    Henderson, P.5    Drummond, H.E.6    Ramsahoye, B.H.7    Wilson, D.C.8    Semple, C.A.9    Satsangi, J.10
  • 68
    • 47949106374 scopus 로고    scopus 로고
    • Epidemiology of inflammatory bowel disease in a German twin cohort: Results of a nationwide study
    • [PMID: 18253950 DOI: 10.1002/ibd.20380]
    • Spehlmann ME, Begun AZ, Burghardt J, Lepage P, Raedler A, Schreiber S. Epidemiology of inflammatory bowel disease in a German twin cohort: results of a nationwide study. Inflamm Bowel Dis 2008; 14: 968-976 [PMID: 18253950 DOI: 10.1002/ibd.20380]
    • (2008) Inflamm Bowel Dis , vol.14 , pp. 968-976
    • Spehlmann, M.E.1    Begun, A.Z.2    Burghardt, J.3    Lepage, P.4    Raedler, A.5    Schreiber, S.6
  • 70
    • 2442563304 scopus 로고    scopus 로고
    • Clinical epidemiology of inflammatory bowel disease: Incidence, prevalence, and environmental influences
    • [PMID: 15168363]
    • Loftus EV. Clinical epidemiology of inflammatory bowel disease: Incidence, prevalence, and environmental influences. Gastroenterology 2004; 126: 1504-1517 [PMID: 15168363]
    • (2004) Gastroenterology , vol.126 , pp. 1504-1517
    • Loftus, E.V.1
  • 71
    • 49349117017 scopus 로고    scopus 로고
    • Incidence and prevalence of inflammatory bowel disease in a Northern California managed care organization, 1996-2002
    • [PMID: 18796097 DOI: 10.1111/j.1572-0241.2008.01960.x]
    • Herrinton LJ, Liu L, Lewis JD, Griffin PM, Allison J. Incidence and prevalence of inflammatory bowel disease in a Northern California managed care organization, 1996-2002. Am J Gastroenterol 2008; 103: 1998-2006 [PMID: 18796097 DOI: 10.1111/j.1572-0241.2008.01960.x]
    • (2008) Am J Gastroenterol , vol.103 , pp. 1998-2006
    • Herrinton, L.J.1    Liu, L.2    Lewis, J.D.3    Griffin, P.M.4    Allison, J.5
  • 72
    • 84871631237 scopus 로고    scopus 로고
    • Identification of disease-associated DNA methylation in B cells from Crohn' s disease and ulcerative colitis patients
    • [PMID: 22821069 DOI: 10.1007/s10620-012-2288-z]
    • Lin Z, Hegarty JP, Yu W, Cappel JA, Chen X, Faber PW, Wang Y, Poritz LS, Fan JB, Koltun WA. Identification of disease-associated DNA methylation in B cells from Crohn' s disease and ulcerative colitis patients. Dig Dis Sci 2012; 57: 3145-3153 [PMID: 22821069 DOI: 10.1007/s10620-012-2288-z]
    • (2012) Dig Dis Sci , vol.57 , pp. 3145-3153
    • Lin, Z.1    Hegarty, J.P.2    Yu, W.3    Cappel, J.A.4    Chen, X.5    Faber, P.W.6    Wang, Y.7    Poritz, L.S.8    Fan, J.B.9    Koltun, W.A.10
  • 75
    • 79958025266 scopus 로고    scopus 로고
    • An endogenously anti-inflammatory role for methylation in mucosal inflammation identified through metabolite profiling
    • [PMID: 21515785 DOI: 10.4049/ jimmunol.1002805]
    • Kominsky DJ, Keely S, MacManus CF, Glover LE, Scully M, Collins CB, Bowers BE, Campbell EL, Colgan SP. An endogenously anti-inflammatory role for methylation in mucosal inflammation identified through metabolite profiling. J Immunol 2011; 186: 6505-6514 [PMID: 21515785 DOI: 10.4049/ jimmunol.1002805]
    • (2011) J Immunol , vol.186 , pp. 6505-6514
    • Kominsky, D.J.1    Keely, S.2    McManus, C.F.3    Glover, L.E.4    Scully, M.5    Collins, C.B.6    Bowers, B.E.7    Campbell, E.L.8    Colgan, S.P.9
  • 78
    • 42449117676 scopus 로고    scopus 로고
    • Hyperhomocysteinemia in inflammatory bowel disease patients without past intestinal resections: Correlations with cobalamin, pyridoxine, folate concentrations, acute phase reactants, disease activity, and prior thromboembolic complications
    • [PMID; 18344891 DOI: 10.1097/MCG.0b013e318046eab0]
    • Erzin Y, Uzun H, Celik AF, Aydin S, Dirican A, Uzunismail H. Hyperhomocysteinemia in inflammatory bowel disease patients without past intestinal resections: correlations with cobalamin, pyridoxine, folate concentrations, acute phase reactants, disease activity, and prior thromboembolic complications. J Clin Gastroenterol 2008; 42: 481-486 [PMID; 18344891 DOI: 10.1097/MCG.0b013e318046eab0]
    • (2008) J Clin Gastroenterol , vol.42 , pp. 481-486
    • Erzin, Y.1    Uzun, H.2    Celik, A.F.3    Aydin, S.4    Dirican, A.5    Uzunismail, H.6
  • 79
    • 77955413734 scopus 로고    scopus 로고
    • Serum vitamin B12 and folate status in patients with inflammatory bowel diseases
    • [PMID: 20603044 DOI: 10.1016/j.ejim.2010.05.007]
    • Yakut M, Ustün Y, Kabaçam G, Soykan I. Serum vitamin B12 and folate status in patients with inflammatory bowel diseases. Eur J Intern Med 2010; 21: 320-323 [PMID: 20603044 DOI: 10.1016/j.ejim.2010.05.007]
    • (2010) Eur J Intern Med , vol.21 , pp. 320-323
    • Yakut, M.1    Ustün, Y.2    Kabaçam, G.3    Soykan, I.4
  • 80
    • 84885761817 scopus 로고    scopus 로고
    • Dietary folate does not significantly affect the intestinal microbiome, inflammation or tumorigenesis in azoxymethane-dextran sodium sulphate-treated mice
    • [PMID: 23021249 DOI: 10.1017/ S0007114512001857]
    • Macfarlane AJ, Behan NA, Matias FM, Green J, Caldwell D, Brooks SP. Dietary folate does not significantly affect the intestinal microbiome, inflammation or tumorigenesis in azoxymethane-dextran sodium sulphate-treated mice. Br J Nutr 2012; 1-9 [PMID: 23021249 DOI: 10.1017/ S0007114512001857]
    • (2012) Br J Nutr , pp. 1-9
    • Macfarlane, A.J.1    Behan, N.A.2    Matias, F.M.3    Green, J.4    Caldwell, D.5    Brooks, S.P.6


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