메뉴 건너뛰기




Volumn 57, Issue 12, 2012, Pages 3145-3153

Identification of disease-associated DNA methylation in B cells from Crohn's disease and ulcerative colitis patients

Author keywords

B cells; DNA methylation; Epigenetics; IL 12 IL 23 pathway; Inflammatory bowel disease

Indexed keywords

BISULFITE;

EID: 84871631237     PISSN: 01632116     EISSN: 15732568     Source Type: Journal    
DOI: 10.1007/s10620-012-2288-z     Document Type: Article
Times cited : (56)

References (33)
  • 1
    • 44349124113 scopus 로고    scopus 로고
    • The genetics and immunopathogenesis of inflammatory bowel disease
    • 18500230 10.1038/nri2340 1:CAS:528:DC%2BD1cXmt1Ojt7o%3D
    • Cho JH. The genetics and immunopathogenesis of inflammatory bowel disease. Nat Rev Immunol. 2008;8:458-466.
    • (2008) Nat Rev Immunol , vol.8 , pp. 458-466
    • Cho, J.H.1
  • 2
    • 17744373329 scopus 로고    scopus 로고
    • Genetics of Crohn disease, an archetypal inflammatory barrier disease
    • 15861209 10.1038/nrg1607 1:CAS:528:DC%2BD2MXjs1OksLc%3D
    • Schreiber S, Rosenstiel P, Albrecht M, et al. Genetics of Crohn disease, an archetypal inflammatory barrier disease. Nat Rev Genet. 2005;6:376-388.
    • (2005) Nat Rev Genet , vol.6 , pp. 376-388
    • Schreiber, S.1    Rosenstiel, P.2    Albrecht, M.3
  • 3
    • 33845340501 scopus 로고    scopus 로고
    • A genome-wide association study identifies IL23R as an inflammatory bowel disease gene
    • 17068223 10.1126/science.1135245 1:CAS:528:DC%2BD28Xht1CntrjF
    • Duerr RH, Taylor KD, Brant SR, et al. A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science. 2006;314:1461-1463.
    • (2006) Science , vol.314 , pp. 1461-1463
    • Duerr, R.H.1    Taylor, K.D.2    Brant, S.R.3
  • 4
    • 33846627302 scopus 로고    scopus 로고
    • A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1
    • 17200669 10.1038/ng1954 1:CAS:528:DC%2BD2sXpvFerug%3D%3D
    • Hampe J, Franke A, Rosenstiel P, et al. A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1. Nat Genet. 2007;39:207-211.
    • (2007) Nat Genet , vol.39 , pp. 207-211
    • Hampe, J.1    Franke, A.2    Rosenstiel, P.3
  • 5
    • 34347338690 scopus 로고    scopus 로고
    • Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility (see comment)
    • 17554261 10.1038/ng2061 1:CAS:528:DC%2BD2sXmvFKlsL4%3D
    • Parkes M, Barrett JC, Prescott NJ, et al. Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility (see comment). Nat Genet. 2007;39:830-832.
    • (2007) Nat Genet , vol.39 , pp. 830-832
    • Parkes, M.1    Barrett, J.C.2    Prescott, N.J.3
  • 6
    • 34247554965 scopus 로고    scopus 로고
    • Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis
    • 17435756 10.1038/ng2032 1:CAS:528:DC%2BD2sXksFersbk%3D
    • Rioux JD, Xavier RJ, Taylor KD, et al. Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. Nat Genet. 2007;39:596-604.
    • (2007) Nat Genet , vol.39 , pp. 596-604
    • Rioux, J.D.1    Xavier, R.J.2    Taylor, K.D.3
  • 7
    • 84969213492 scopus 로고    scopus 로고
    • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
    • Wellcome Trust Case Control Consortium 10.1038/nature05911 1:CAS:528:DC%2BD2sXmtFelsb0%3D
    • Wellcome Trust Case Control Consortium, Burton PR, Clayton DG, et al. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature. 2007;447:661-678.
    • (2007) Nature , vol.447 , pp. 661-678
    • Burton, P.R.1    Clayton, D.G.2
  • 8
    • 27944464550 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease
    • 16221758 10.1093/hmg/ddi379 1:CAS:528:DC%2BD2MXhtFymtbvP
    • Yamazaki K, McGovern D, Ragoussis J, et al. Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease. Hum Mol Genet. 2005;14:3499-3506.
    • (2005) Hum Mol Genet , vol.14 , pp. 3499-3506
    • Yamazaki, K.1    McGovern, D.2    Ragoussis, J.3
  • 9
    • 48349136889 scopus 로고    scopus 로고
    • Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
    • 18587394 10.1038/ng.175 1:CAS:528:DC%2BD1cXptFSqs7k%3D
    • Barrett JC, Hansoul S, Nicolae DL, et al. Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. Nat Genet. 2008;40:955-962.
    • (2008) Nat Genet , vol.40 , pp. 955-962
    • Barrett, J.C.1    Hansoul, S.2    Nicolae, D.L.3
  • 10
    • 48749084893 scopus 로고    scopus 로고
    • Genome-wide association studies: A new window into immune-mediated diseases
    • 18654571 10.1038/nri2361 1:CAS:528:DC%2BD1cXovV2gtrY%3D
    • Xavier RJ, Rioux JD. Genome-wide association studies: a new window into immune-mediated diseases. Nat Rev Immunol. 2008;8:631-643.
    • (2008) Nat Rev Immunol , vol.8 , pp. 631-643
    • Xavier, R.J.1    Rioux, J.D.2
  • 11
    • 0036855609 scopus 로고    scopus 로고
    • DNA methylation changes in gastrointestinal disease
    • 12572875 10.1007/s535-002-8138-1 1:CAS:528:DC%2BD38XpsleqtLY%3D
    • Toyota M, Itoh F, Kikuchi T, et al. DNA methylation changes in gastrointestinal disease. J Gastroenterol. 2002;37:97-101.
    • (2002) J Gastroenterol , vol.37 , pp. 97-101
    • Toyota, M.1    Itoh, F.2    Kikuchi, T.3
  • 12
    • 33845890020 scopus 로고    scopus 로고
    • DNA hypermethylation in colorectal neoplasms and inflammatory bowel disease: A mini review
    • 17093903 10.1007/s10787-006-1540-6 1:CAS:528:DC%2BD2sXhvFyrsb8%3D
    • Maeda O, Ando T, Watanabe O, et al. DNA hypermethylation in colorectal neoplasms and inflammatory bowel disease: a mini review. Inflammopharmacology. 2006;14:204-206.
    • (2006) Inflammopharmacology , vol.14 , pp. 204-206
    • Maeda, O.1    Ando, T.2    Watanabe, O.3
  • 13
    • 79958119436 scopus 로고    scopus 로고
    • Identification of diseased-associated DNA methylation in intestinal tissues from patients with inflammatory bowel disease
    • 20950376 10.1111/j.1399-0004.2010.01546.x 1:CAS:528:DC%2BC3MXpsVCqs78%3D
    • Lin Z, Hegarty JP, Cappel JA, et al. Identification of diseased-associated DNA methylation in intestinal tissues from patients with inflammatory bowel disease. Clin Genet. 2011;80:59-67.
    • (2011) Clin Genet , vol.80 , pp. 59-67
    • Lin, Z.1    Hegarty, J.P.2    Cappel, J.A.3
  • 14
    • 67651085303 scopus 로고    scopus 로고
    • Association of Nk2-3 polymorphism with Crohn's disease and expression of Nk2-3 is up-regulated in B cell lines and intestinal tissues with Crohn's disease
    • 10.1016/j.crohns.2009.04.003
    • Yu W, Lin Z, Kelly AA, et al. Association of Nk2-3 polymorphism with Crohn's disease and expression of Nk2-3 is up-regulated in B cell lines and intestinal tissues with Crohn's disease. J Crohn's Colitis. 2009;3:189-195.
    • (2009) J Crohn's Colitis , vol.3 , pp. 189-195
    • Yu, W.1    Lin, Z.2    Kelly, A.A.3
  • 15
    • 34548590250 scopus 로고    scopus 로고
    • DNA methylation markers of surfactant proteins in lung cancer
    • 17549420 1:CAS:528:DC%2BD2sXot1Ojsrk%3D
    • Lin Z, Thomas NJ, Bibikova M, et al. DNA methylation markers of surfactant proteins in lung cancer. Int J Oncol. 2007;31:181-191.
    • (2007) Int J Oncol , vol.31 , pp. 181-191
    • Lin, Z.1    Thomas, N.J.2    Bibikova, M.3
  • 16
    • 33644649616 scopus 로고    scopus 로고
    • High-throughput DNA methylation profiling using universal bead arrays
    • 16449502 10.1101/gr.4410706 1:CAS:528:DC%2BD28Xit1Kntrg%3D
    • Bibikova M, Lin Z, Zhou L, et al. High-throughput DNA methylation profiling using universal bead arrays. Genome Res. 2006;16:383-393.
    • (2006) Genome Res , vol.16 , pp. 383-393
    • Bibikova, M.1    Lin, Z.2    Zhou, L.3
  • 17
    • 70450169678 scopus 로고    scopus 로고
    • Epigenetic profiling of somatic tissues from human autopsy specimens identifies tissue- and individual-specific DNA methylation patterns
    • 19776032 10.1093/hmg/ddp445 1:CAS:528:DC%2BD1MXhsVGltbjN
    • Byun HM, Siegmund KD, Pan F, et al. Epigenetic profiling of somatic tissues from human autopsy specimens identifies tissue- and individual-specific DNA methylation patterns. Hum Mol Genet. 2009;18:4808-4817.
    • (2009) Hum Mol Genet , vol.18 , pp. 4808-4817
    • Byun, H.M.1    Siegmund, K.D.2    Pan, F.3
  • 18
    • 34948840330 scopus 로고    scopus 로고
    • The IL23 axis plays a key role in the pathogenesis of IBD
    • 17872562 10.1136/gut.2006.115402 1:CAS:528:DC%2BD2sXht1SrsbvO
    • McGovern D, Powrie F. The IL23 axis plays a key role in the pathogenesis of IBD. Gut. 2007;56:1333-1336.
    • (2007) Gut , vol.56 , pp. 1333-1336
    • McGovern, D.1    Powrie, F.2
  • 19
    • 61549115034 scopus 로고    scopus 로고
    • Diverse genome-wide association studies associate the IL12/IL23 pathway with Crohn Disease
    • 19249008 10.1016/j.ajhg.2009.01.026 1:CAS:528:DC%2BD1MXmvFClsrk%3D
    • Wang K, Zhang H, Kugathasan S, et al. Diverse genome-wide association studies associate the IL12/IL23 pathway with Crohn Disease. Am J Hum Genet. 2009;84:399-405.
    • (2009) Am J Hum Genet , vol.84 , pp. 399-405
    • Wang, K.1    Zhang, H.2    Kugathasan, S.3
  • 20
    • 33751505540 scopus 로고    scopus 로고
    • DNA methylation profiling of human chromosomes 6, 20 and 22 (see comment)
    • 17072317 10.1038/ng1909 1:CAS:528:DC%2BD28Xht1CntrbK
    • Eckhardt F, Lewin J, Cortese R, et al. DNA methylation profiling of human chromosomes 6, 20 and 22 (see comment). Nat Genet. 2006;38:1378-1385.
    • (2006) Nat Genet , vol.38 , pp. 1378-1385
    • Eckhardt, F.1    Lewin, J.2    Cortese, R.3
  • 21
    • 3042678551 scopus 로고    scopus 로고
    • Decreased T cell ERK pathway signaling may contribute to the development of lupus through effects on DNA methylation and gene expression
    • 15204091 10.1080/08830180490452567 1:CAS:528:DC%2BD2cXjvVCitb0%3D
    • Oelke K, Richardson B. Decreased T cell ERK pathway signaling may contribute to the development of lupus through effects on DNA methylation and gene expression. Int Rev Immunol. 2004;23:315-331.
    • (2004) Int Rev Immunol , vol.23 , pp. 315-331
    • Oelke, K.1    Richardson, B.2
  • 22
    • 20044390368 scopus 로고    scopus 로고
    • DNA methylation profiling of the human major histocompatibility complex: A pilot study for the human epigenome project
    • 15550986 10.1371/journal.pbio.0020405
    • Rakyan VK, Hildmann T, Novik KL, et al. DNA methylation profiling of the human major histocompatibility complex: a pilot study for the human epigenome project. PLoS Biol. 2004;2:e405.
    • (2004) PLoS Biol , vol.2 , pp. 405
    • Rakyan, V.K.1    Hildmann, T.2    Novik, K.L.3
  • 23
    • 33847639998 scopus 로고    scopus 로고
    • The B-cell system in inflammatory bowel disease
    • 16620017 10.1007/0-387-33778-4-10 1:CAS:528:DC%2BD1MXhtFWjtLo%3D
    • Brandtzaeg P, Carlsen HS, Halstensen TS. The B-cell system in inflammatory bowel disease. Adv Exp Med Biol. 2006;579:149-167.
    • (2006) Adv Exp Med Biol , vol.579 , pp. 149-167
    • Brandtzaeg, P.1    Carlsen, H.S.2    Halstensen, T.S.3
  • 24
    • 1842426643 scopus 로고    scopus 로고
    • An innate cell-mediated, murine ulcerative colitis-like syndrome in the absence of nuclear factor of activated T cells
    • 15057750 10.1053/j.gastro.2004.01.013 1:CAS:528:DC%2BD2cXkt1Krt7w%3D
    • Gerth AJ, Lin L, Neurath MF, et al. An innate cell-mediated, murine ulcerative colitis-like syndrome in the absence of nuclear factor of activated T cells. Gastroenterology. 2004;126:1115-1121.
    • (2004) Gastroenterology , vol.126 , pp. 1115-1121
    • Gerth, A.J.1    Lin, L.2    Neurath, M.F.3
  • 25
    • 0036197923 scopus 로고    scopus 로고
    • Chronic intestinal inflammatory condition generates IL-10-producing regulatory B cell subset characterized by CD1d upregulation
    • 11869683 10.1016/S1074-7613(02)00274-1 1:CAS:528:DC%2BD38XitVCisrw%3D
    • Mizoguchi A, Mizoguchi E, Takedatsu H, et al. Chronic intestinal inflammatory condition generates IL-10-producing regulatory B cell subset characterized by CD1d upregulation. Immunity. 2002;16:219-230.
    • (2002) Immunity , vol.16 , pp. 219-230
    • Mizoguchi, A.1    Mizoguchi, E.2    Takedatsu, H.3
  • 26
    • 70349640926 scopus 로고    scopus 로고
    • Hyperactivated B cells in human inflammatory bowel disease
    • 19589946 10.1189/jlb.0309203 1:CAS:528:DC%2BD1MXht1eru7%2FE
    • Noronha AM, Liang Y, Hetzel JT, et al. Hyperactivated B cells in human inflammatory bowel disease. J Leukoc Biol. 2009;86:1007-1016.
    • (2009) J Leukoc Biol , vol.86 , pp. 1007-1016
    • Noronha, A.M.1    Liang, Y.2    Hetzel, J.T.3
  • 27
    • 10044252330 scopus 로고    scopus 로고
    • Variable methylation of the Epstein-Barr virus Wp EBNA gene promoter in B-lymphoblastoid cell lines
    • 15564516 10.1128/JVI.78.24.14062-14065.2004 1:CAS:528:DC%2BD2cXhtFSisLrP
    • Elliott J, Goodhew EB, Krug LT, et al. Variable methylation of the Epstein-Barr virus Wp EBNA gene promoter in B-lymphoblastoid cell lines. J Virol. 2004;78:14062-14065.
    • (2004) J Virol , vol.78 , pp. 14062-14065
    • Elliott, J.1    Goodhew, E.B.2    Krug, L.T.3
  • 28
    • 76249132533 scopus 로고    scopus 로고
    • AP-1 homolog BZLF1 of Epstein-Barr virus has two essential functions dependent on the epigenetic state of the viral genome
    • 20080764 10.1073/pnas.0911948107 1:CAS:528:DC%2BC3cXhtVOrsrg%3D
    • Kalla M, Schmeinck A, Bergbauer M, et al. AP-1 homolog BZLF1 of Epstein-Barr virus has two essential functions dependent on the epigenetic state of the viral genome. Proc Natl Acad Sci USA. 2010;107:850-855.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 850-855
    • Kalla, M.1    Schmeinck, A.2    Bergbauer, M.3
  • 29
    • 63449133614 scopus 로고    scopus 로고
    • Epigenetic dysregulation of the host cell genome in Epstein-Barr virus-associated neoplasia
    • 19429479 10.1016/j.semcancer.2009.02.012 1:CAS:528:DC%2BD1MXktV2is7c%3D
    • Niller HH, Wolf H, Minarovits J. Epigenetic dysregulation of the host cell genome in Epstein-Barr virus-associated neoplasia. Semin Cancer Biol. 2009;19:158-164.
    • (2009) Semin Cancer Biol , vol.19 , pp. 158-164
    • Niller, H.H.1    Wolf, H.2    Minarovits, J.3
  • 30
    • 77953397656 scopus 로고    scopus 로고
    • Comparison of the DNA methylation profiles of human peripheral blood cells and transformed B-lymphocytes
    • 20238126 10.1007/s00439-010-0810-y 1:CAS:528:DC%2BC3cXmtV2js7o%3D
    • Sun YV, Turner ST, Smith JA, et al. Comparison of the DNA methylation profiles of human peripheral blood cells and transformed B-lymphocytes. Hum Genet. 2010;127:651-658.
    • (2010) Hum Genet , vol.127 , pp. 651-658
    • Sun, Y.V.1    Turner, S.T.2    Smith, J.A.3
  • 31
    • 75449099720 scopus 로고    scopus 로고
    • EBV transformation and cell culturing destabilizes DNA methylation in human lymphoblastoid cell lines
    • 20005943 10.1016/j.ygeno.2009.12.001 1:CAS:528:DC%2BC3cXhs1Wjsbs%3D
    • Grafodatskaya D, Choufani S, Ferreira JC. EBV transformation and cell culturing destabilizes DNA methylation in human lymphoblastoid cell lines. Genomics. 2010;95:73-83.
    • (2010) Genomics , vol.95 , pp. 73-83
    • Grafodatskaya, D.1    Choufani, S.2    Ferreira, J.C.3
  • 32
    • 34848918829 scopus 로고    scopus 로고
    • Comparing the DNA hypermethylome with gene mutations in human colorectal cancer
    • 17892325 10.1371/journal.pgen.0030157 1:CAS:528:DC%2BD2sXhtFKmt77O
    • Schuebel KE, Chen W, Cope L, et al. Comparing the DNA hypermethylome with gene mutations in human colorectal cancer. PLoS Genet. 2007;3:1709-1723.
    • (2007) PLoS Genet , vol.3 , pp. 1709-1723
    • Schuebel, K.E.1    Chen, W.2    Cope, L.3
  • 33
    • 33745389259 scopus 로고    scopus 로고
    • DNA methylation as a marker for the past and future
    • 16799880 10.1007/s00535-006-1846-6 1:CAS:528:DC%2BD28XmtFKjsr8%3D
    • Ushijima T, Nakajima T, Maekita T. DNA methylation as a marker for the past and future. J Gastroenterol. 2006;41:401-407.
    • (2006) J Gastroenterol , vol.41 , pp. 401-407
    • Ushijima, T.1    Nakajima, T.2    Maekita, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.