-
1
-
-
44349124113
-
The genetics and immunopathogenesis of inflammatory bowel disease
-
18500230 10.1038/nri2340 1:CAS:528:DC%2BD1cXmt1Ojt7o%3D
-
Cho JH. The genetics and immunopathogenesis of inflammatory bowel disease. Nat Rev Immunol. 2008;8:458-466.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 458-466
-
-
Cho, J.H.1
-
2
-
-
17744373329
-
Genetics of Crohn disease, an archetypal inflammatory barrier disease
-
15861209 10.1038/nrg1607 1:CAS:528:DC%2BD2MXjs1OksLc%3D
-
Schreiber S, Rosenstiel P, Albrecht M, et al. Genetics of Crohn disease, an archetypal inflammatory barrier disease. Nat Rev Genet. 2005;6:376-388.
-
(2005)
Nat Rev Genet
, vol.6
, pp. 376-388
-
-
Schreiber, S.1
Rosenstiel, P.2
Albrecht, M.3
-
3
-
-
33845340501
-
A genome-wide association study identifies IL23R as an inflammatory bowel disease gene
-
17068223 10.1126/science.1135245 1:CAS:528:DC%2BD28Xht1CntrjF
-
Duerr RH, Taylor KD, Brant SR, et al. A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science. 2006;314:1461-1463.
-
(2006)
Science
, vol.314
, pp. 1461-1463
-
-
Duerr, R.H.1
Taylor, K.D.2
Brant, S.R.3
-
4
-
-
33846627302
-
A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1
-
17200669 10.1038/ng1954 1:CAS:528:DC%2BD2sXpvFerug%3D%3D
-
Hampe J, Franke A, Rosenstiel P, et al. A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1. Nat Genet. 2007;39:207-211.
-
(2007)
Nat Genet
, vol.39
, pp. 207-211
-
-
Hampe, J.1
Franke, A.2
Rosenstiel, P.3
-
5
-
-
34347338690
-
Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility (see comment)
-
17554261 10.1038/ng2061 1:CAS:528:DC%2BD2sXmvFKlsL4%3D
-
Parkes M, Barrett JC, Prescott NJ, et al. Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility (see comment). Nat Genet. 2007;39:830-832.
-
(2007)
Nat Genet
, vol.39
, pp. 830-832
-
-
Parkes, M.1
Barrett, J.C.2
Prescott, N.J.3
-
6
-
-
34247554965
-
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis
-
17435756 10.1038/ng2032 1:CAS:528:DC%2BD2sXksFersbk%3D
-
Rioux JD, Xavier RJ, Taylor KD, et al. Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. Nat Genet. 2007;39:596-604.
-
(2007)
Nat Genet
, vol.39
, pp. 596-604
-
-
Rioux, J.D.1
Xavier, R.J.2
Taylor, K.D.3
-
7
-
-
84969213492
-
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
-
Wellcome Trust Case Control Consortium 10.1038/nature05911 1:CAS:528:DC%2BD2sXmtFelsb0%3D
-
Wellcome Trust Case Control Consortium, Burton PR, Clayton DG, et al. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature. 2007;447:661-678.
-
(2007)
Nature
, vol.447
, pp. 661-678
-
-
Burton, P.R.1
Clayton, D.G.2
-
8
-
-
27944464550
-
Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease
-
16221758 10.1093/hmg/ddi379 1:CAS:528:DC%2BD2MXhtFymtbvP
-
Yamazaki K, McGovern D, Ragoussis J, et al. Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease. Hum Mol Genet. 2005;14:3499-3506.
-
(2005)
Hum Mol Genet
, vol.14
, pp. 3499-3506
-
-
Yamazaki, K.1
McGovern, D.2
Ragoussis, J.3
-
9
-
-
48349136889
-
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
-
18587394 10.1038/ng.175 1:CAS:528:DC%2BD1cXptFSqs7k%3D
-
Barrett JC, Hansoul S, Nicolae DL, et al. Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. Nat Genet. 2008;40:955-962.
-
(2008)
Nat Genet
, vol.40
, pp. 955-962
-
-
Barrett, J.C.1
Hansoul, S.2
Nicolae, D.L.3
-
10
-
-
48749084893
-
Genome-wide association studies: A new window into immune-mediated diseases
-
18654571 10.1038/nri2361 1:CAS:528:DC%2BD1cXovV2gtrY%3D
-
Xavier RJ, Rioux JD. Genome-wide association studies: a new window into immune-mediated diseases. Nat Rev Immunol. 2008;8:631-643.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 631-643
-
-
Xavier, R.J.1
Rioux, J.D.2
-
11
-
-
0036855609
-
DNA methylation changes in gastrointestinal disease
-
12572875 10.1007/s535-002-8138-1 1:CAS:528:DC%2BD38XpsleqtLY%3D
-
Toyota M, Itoh F, Kikuchi T, et al. DNA methylation changes in gastrointestinal disease. J Gastroenterol. 2002;37:97-101.
-
(2002)
J Gastroenterol
, vol.37
, pp. 97-101
-
-
Toyota, M.1
Itoh, F.2
Kikuchi, T.3
-
12
-
-
33845890020
-
DNA hypermethylation in colorectal neoplasms and inflammatory bowel disease: A mini review
-
17093903 10.1007/s10787-006-1540-6 1:CAS:528:DC%2BD2sXhvFyrsb8%3D
-
Maeda O, Ando T, Watanabe O, et al. DNA hypermethylation in colorectal neoplasms and inflammatory bowel disease: a mini review. Inflammopharmacology. 2006;14:204-206.
-
(2006)
Inflammopharmacology
, vol.14
, pp. 204-206
-
-
Maeda, O.1
Ando, T.2
Watanabe, O.3
-
13
-
-
79958119436
-
Identification of diseased-associated DNA methylation in intestinal tissues from patients with inflammatory bowel disease
-
20950376 10.1111/j.1399-0004.2010.01546.x 1:CAS:528:DC%2BC3MXpsVCqs78%3D
-
Lin Z, Hegarty JP, Cappel JA, et al. Identification of diseased-associated DNA methylation in intestinal tissues from patients with inflammatory bowel disease. Clin Genet. 2011;80:59-67.
-
(2011)
Clin Genet
, vol.80
, pp. 59-67
-
-
Lin, Z.1
Hegarty, J.P.2
Cappel, J.A.3
-
14
-
-
67651085303
-
Association of Nk2-3 polymorphism with Crohn's disease and expression of Nk2-3 is up-regulated in B cell lines and intestinal tissues with Crohn's disease
-
10.1016/j.crohns.2009.04.003
-
Yu W, Lin Z, Kelly AA, et al. Association of Nk2-3 polymorphism with Crohn's disease and expression of Nk2-3 is up-regulated in B cell lines and intestinal tissues with Crohn's disease. J Crohn's Colitis. 2009;3:189-195.
-
(2009)
J Crohn's Colitis
, vol.3
, pp. 189-195
-
-
Yu, W.1
Lin, Z.2
Kelly, A.A.3
-
15
-
-
34548590250
-
DNA methylation markers of surfactant proteins in lung cancer
-
17549420 1:CAS:528:DC%2BD2sXot1Ojsrk%3D
-
Lin Z, Thomas NJ, Bibikova M, et al. DNA methylation markers of surfactant proteins in lung cancer. Int J Oncol. 2007;31:181-191.
-
(2007)
Int J Oncol
, vol.31
, pp. 181-191
-
-
Lin, Z.1
Thomas, N.J.2
Bibikova, M.3
-
16
-
-
33644649616
-
High-throughput DNA methylation profiling using universal bead arrays
-
16449502 10.1101/gr.4410706 1:CAS:528:DC%2BD28Xit1Kntrg%3D
-
Bibikova M, Lin Z, Zhou L, et al. High-throughput DNA methylation profiling using universal bead arrays. Genome Res. 2006;16:383-393.
-
(2006)
Genome Res
, vol.16
, pp. 383-393
-
-
Bibikova, M.1
Lin, Z.2
Zhou, L.3
-
17
-
-
70450169678
-
Epigenetic profiling of somatic tissues from human autopsy specimens identifies tissue- and individual-specific DNA methylation patterns
-
19776032 10.1093/hmg/ddp445 1:CAS:528:DC%2BD1MXhsVGltbjN
-
Byun HM, Siegmund KD, Pan F, et al. Epigenetic profiling of somatic tissues from human autopsy specimens identifies tissue- and individual-specific DNA methylation patterns. Hum Mol Genet. 2009;18:4808-4817.
-
(2009)
Hum Mol Genet
, vol.18
, pp. 4808-4817
-
-
Byun, H.M.1
Siegmund, K.D.2
Pan, F.3
-
18
-
-
34948840330
-
The IL23 axis plays a key role in the pathogenesis of IBD
-
17872562 10.1136/gut.2006.115402 1:CAS:528:DC%2BD2sXht1SrsbvO
-
McGovern D, Powrie F. The IL23 axis plays a key role in the pathogenesis of IBD. Gut. 2007;56:1333-1336.
-
(2007)
Gut
, vol.56
, pp. 1333-1336
-
-
McGovern, D.1
Powrie, F.2
-
19
-
-
61549115034
-
Diverse genome-wide association studies associate the IL12/IL23 pathway with Crohn Disease
-
19249008 10.1016/j.ajhg.2009.01.026 1:CAS:528:DC%2BD1MXmvFClsrk%3D
-
Wang K, Zhang H, Kugathasan S, et al. Diverse genome-wide association studies associate the IL12/IL23 pathway with Crohn Disease. Am J Hum Genet. 2009;84:399-405.
-
(2009)
Am J Hum Genet
, vol.84
, pp. 399-405
-
-
Wang, K.1
Zhang, H.2
Kugathasan, S.3
-
20
-
-
33751505540
-
DNA methylation profiling of human chromosomes 6, 20 and 22 (see comment)
-
17072317 10.1038/ng1909 1:CAS:528:DC%2BD28Xht1CntrbK
-
Eckhardt F, Lewin J, Cortese R, et al. DNA methylation profiling of human chromosomes 6, 20 and 22 (see comment). Nat Genet. 2006;38:1378-1385.
-
(2006)
Nat Genet
, vol.38
, pp. 1378-1385
-
-
Eckhardt, F.1
Lewin, J.2
Cortese, R.3
-
21
-
-
3042678551
-
Decreased T cell ERK pathway signaling may contribute to the development of lupus through effects on DNA methylation and gene expression
-
15204091 10.1080/08830180490452567 1:CAS:528:DC%2BD2cXjvVCitb0%3D
-
Oelke K, Richardson B. Decreased T cell ERK pathway signaling may contribute to the development of lupus through effects on DNA methylation and gene expression. Int Rev Immunol. 2004;23:315-331.
-
(2004)
Int Rev Immunol
, vol.23
, pp. 315-331
-
-
Oelke, K.1
Richardson, B.2
-
22
-
-
20044390368
-
DNA methylation profiling of the human major histocompatibility complex: A pilot study for the human epigenome project
-
15550986 10.1371/journal.pbio.0020405
-
Rakyan VK, Hildmann T, Novik KL, et al. DNA methylation profiling of the human major histocompatibility complex: a pilot study for the human epigenome project. PLoS Biol. 2004;2:e405.
-
(2004)
PLoS Biol
, vol.2
, pp. 405
-
-
Rakyan, V.K.1
Hildmann, T.2
Novik, K.L.3
-
23
-
-
33847639998
-
The B-cell system in inflammatory bowel disease
-
16620017 10.1007/0-387-33778-4-10 1:CAS:528:DC%2BD1MXhtFWjtLo%3D
-
Brandtzaeg P, Carlsen HS, Halstensen TS. The B-cell system in inflammatory bowel disease. Adv Exp Med Biol. 2006;579:149-167.
-
(2006)
Adv Exp Med Biol
, vol.579
, pp. 149-167
-
-
Brandtzaeg, P.1
Carlsen, H.S.2
Halstensen, T.S.3
-
24
-
-
1842426643
-
An innate cell-mediated, murine ulcerative colitis-like syndrome in the absence of nuclear factor of activated T cells
-
15057750 10.1053/j.gastro.2004.01.013 1:CAS:528:DC%2BD2cXkt1Krt7w%3D
-
Gerth AJ, Lin L, Neurath MF, et al. An innate cell-mediated, murine ulcerative colitis-like syndrome in the absence of nuclear factor of activated T cells. Gastroenterology. 2004;126:1115-1121.
-
(2004)
Gastroenterology
, vol.126
, pp. 1115-1121
-
-
Gerth, A.J.1
Lin, L.2
Neurath, M.F.3
-
25
-
-
0036197923
-
Chronic intestinal inflammatory condition generates IL-10-producing regulatory B cell subset characterized by CD1d upregulation
-
11869683 10.1016/S1074-7613(02)00274-1 1:CAS:528:DC%2BD38XitVCisrw%3D
-
Mizoguchi A, Mizoguchi E, Takedatsu H, et al. Chronic intestinal inflammatory condition generates IL-10-producing regulatory B cell subset characterized by CD1d upregulation. Immunity. 2002;16:219-230.
-
(2002)
Immunity
, vol.16
, pp. 219-230
-
-
Mizoguchi, A.1
Mizoguchi, E.2
Takedatsu, H.3
-
26
-
-
70349640926
-
Hyperactivated B cells in human inflammatory bowel disease
-
19589946 10.1189/jlb.0309203 1:CAS:528:DC%2BD1MXht1eru7%2FE
-
Noronha AM, Liang Y, Hetzel JT, et al. Hyperactivated B cells in human inflammatory bowel disease. J Leukoc Biol. 2009;86:1007-1016.
-
(2009)
J Leukoc Biol
, vol.86
, pp. 1007-1016
-
-
Noronha, A.M.1
Liang, Y.2
Hetzel, J.T.3
-
27
-
-
10044252330
-
Variable methylation of the Epstein-Barr virus Wp EBNA gene promoter in B-lymphoblastoid cell lines
-
15564516 10.1128/JVI.78.24.14062-14065.2004 1:CAS:528:DC%2BD2cXhtFSisLrP
-
Elliott J, Goodhew EB, Krug LT, et al. Variable methylation of the Epstein-Barr virus Wp EBNA gene promoter in B-lymphoblastoid cell lines. J Virol. 2004;78:14062-14065.
-
(2004)
J Virol
, vol.78
, pp. 14062-14065
-
-
Elliott, J.1
Goodhew, E.B.2
Krug, L.T.3
-
28
-
-
76249132533
-
AP-1 homolog BZLF1 of Epstein-Barr virus has two essential functions dependent on the epigenetic state of the viral genome
-
20080764 10.1073/pnas.0911948107 1:CAS:528:DC%2BC3cXhtVOrsrg%3D
-
Kalla M, Schmeinck A, Bergbauer M, et al. AP-1 homolog BZLF1 of Epstein-Barr virus has two essential functions dependent on the epigenetic state of the viral genome. Proc Natl Acad Sci USA. 2010;107:850-855.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 850-855
-
-
Kalla, M.1
Schmeinck, A.2
Bergbauer, M.3
-
29
-
-
63449133614
-
Epigenetic dysregulation of the host cell genome in Epstein-Barr virus-associated neoplasia
-
19429479 10.1016/j.semcancer.2009.02.012 1:CAS:528:DC%2BD1MXktV2is7c%3D
-
Niller HH, Wolf H, Minarovits J. Epigenetic dysregulation of the host cell genome in Epstein-Barr virus-associated neoplasia. Semin Cancer Biol. 2009;19:158-164.
-
(2009)
Semin Cancer Biol
, vol.19
, pp. 158-164
-
-
Niller, H.H.1
Wolf, H.2
Minarovits, J.3
-
30
-
-
77953397656
-
Comparison of the DNA methylation profiles of human peripheral blood cells and transformed B-lymphocytes
-
20238126 10.1007/s00439-010-0810-y 1:CAS:528:DC%2BC3cXmtV2js7o%3D
-
Sun YV, Turner ST, Smith JA, et al. Comparison of the DNA methylation profiles of human peripheral blood cells and transformed B-lymphocytes. Hum Genet. 2010;127:651-658.
-
(2010)
Hum Genet
, vol.127
, pp. 651-658
-
-
Sun, Y.V.1
Turner, S.T.2
Smith, J.A.3
-
31
-
-
75449099720
-
EBV transformation and cell culturing destabilizes DNA methylation in human lymphoblastoid cell lines
-
20005943 10.1016/j.ygeno.2009.12.001 1:CAS:528:DC%2BC3cXhs1Wjsbs%3D
-
Grafodatskaya D, Choufani S, Ferreira JC. EBV transformation and cell culturing destabilizes DNA methylation in human lymphoblastoid cell lines. Genomics. 2010;95:73-83.
-
(2010)
Genomics
, vol.95
, pp. 73-83
-
-
Grafodatskaya, D.1
Choufani, S.2
Ferreira, J.C.3
-
32
-
-
34848918829
-
Comparing the DNA hypermethylome with gene mutations in human colorectal cancer
-
17892325 10.1371/journal.pgen.0030157 1:CAS:528:DC%2BD2sXhtFKmt77O
-
Schuebel KE, Chen W, Cope L, et al. Comparing the DNA hypermethylome with gene mutations in human colorectal cancer. PLoS Genet. 2007;3:1709-1723.
-
(2007)
PLoS Genet
, vol.3
, pp. 1709-1723
-
-
Schuebel, K.E.1
Chen, W.2
Cope, L.3
-
33
-
-
33745389259
-
DNA methylation as a marker for the past and future
-
16799880 10.1007/s00535-006-1846-6 1:CAS:528:DC%2BD28XmtFKjsr8%3D
-
Ushijima T, Nakajima T, Maekita T. DNA methylation as a marker for the past and future. J Gastroenterol. 2006;41:401-407.
-
(2006)
J Gastroenterol
, vol.41
, pp. 401-407
-
-
Ushijima, T.1
Nakajima, T.2
Maekita, T.3
|