Methyl deficient diet aggravates experimental colitis in rats

Journal of Cellular and Molecular Medicine

Volumn 15, Issue 11, 2011, Pages 2486-2497

  Chen, Min ^a,b   Peyrin Biroulet, Laurent ^a   George, Amandine ^a   Coste, Florence ^a   Bressenot, Aude ^a   Bossenmeyer Pourie, Carine ^a   Alberto, Jean Marc ^a   Xia, Bing ^b   Namour, Bernard ^a   Guéant, Jean Louis ^a  

^a UNIVERSITÉ DE LORRAINE   (France)

^b WUHAN UNIVERSITY   (China)

Author keywords

Choline; Folate; Inflammation; Inflammatory bowel diseases; Methyl donors; Vitamin B12

Indexed keywords

CASPASE 3; CYANOCOBALAMIN; CYCLOOXYGENASE 2; DEXTRAN SULFATE; FOLIC ACID; GLUTATHIONE PEROXIDASE; HOMOCYSTEINE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHOLIPASE A2; PROTEIN BAX; PROTEIN BCL 2; SUPEROXIDE DISMUTASE; TISSUE INHIBITOR OF METALLOPROTEINASE 3; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL; APOPTOSIS; ARTICLE; BIOSYNTHESIS; BLOOD; CHEMICALLY INDUCED DISORDER; COLON; CYANOCOBALAMIN DEFICIENCY; DIET; DRUG EFFECT; FOLIC ACID DEFICIENCY; METABOLISM; OXIDATIVE STRESS; PATHOLOGY; RAT; ULCERATIVE COLITIS; VITAMIN DEFICIENCY; WISTAR RAT;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CHOLINE DEFICIENCY; COLITIS, ULCERATIVE; COLON; CYCLOOXYGENASE 2; DEXTRAN SULFATE; DIET; FOLIC ACID; FOLIC ACID DEFICIENCY; GLUTATHIONE PEROXIDASE; HOMOCYSTEINE; OXIDATIVE STRESS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHOLIPASES A2; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, WISTAR; RNA, MESSENGER; SUPEROXIDE DISMUTASE; TISSUE INHIBITOR OF METALLOPROTEINASE-3; TUMOR NECROSIS FACTOR-ALPHA; VITAMIN B 12; VITAMIN B 12 DEFICIENCY;

RATTUS;

EID: 80054946988     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1582-4934.2010.01252.x     Document Type: Article

References (55)

1. Xavier RJ, Podolsky DK. Unravelling the pathogenesis of inflammatory bowel disease. Nature. 2007; 448: 427-34.
2. Peyrin-Biroulet L, Desreumaux P, Sandborn WJ, et al Crohn's disease: beyond antagonists of tumour necrosis factor. Lancet. 2008; 372: 67-81.
3. Peyrin-Biroulet L, Gueant-Rodriguez RM, Chen M, et al Association of MTRR 66A>G polymorphism with superoxide dismutase and disease activity in patients with Crohn's disease. Am J Gastroenterol. 2008; 103: 399-406.
4. Peyrin-Biroulet L, Rodriguez-Gueant RM, Chamaillard M, et al Vascular and cellular stress in inflammatory bowel disease: revisiting the role of homocysteine. Am J Gastroenterol. 2007; 102: 1108-15.
5. Danese S, Sgambato A, Papa A, et al Homocysteine triggers mucosal microvascular activation in inflammatory bowel disease. Am J Gastroenterol. 2005; 100: 886-95.
6. Morgenstern I, Raijmakers MT, Peters WH, et al Homocysteine, cysteine, and glutathione in human colonic mucosa: elevated levels of homocysteine in patients with inflammatory bowel disease. Dig Dis Sci. 2003; 48: 2083-90.
7. Poddar R, Sivasubramanian N, DiBello PM, et al Homocysteine induces expression and secretion of monocyte chemoattractant protein-1 and interleukin-8 in human aortic endothelial cells: implications for vascular disease. Circulation. 2001; 103: 2717-23.
8. Collins T, Cybulsky MI. NF-kappaB: pivotal mediator or innocent bystander in atherogenesis? J Clin Invest. 2001; 107: 255-64.
9. Moat SJ, Bonham JR, Cragg RA, et al Elevated plasma homocysteine elicits an increase in antioxidant enzyme activity. Free Radic Res. 2000; 32: 171-9.
10. Wang XL, Duarte N, Cai H, et al Relationship between total plasma homocysteine, polymorphisms of homocysteine metabolism related enzymes, risk factors and coronary artery disease in the Australian hospital-based population. Atherosclerosis. 1999; 146: 133-40.
11. Nishio E, Watanabe Y. Homocysteine as a modulator of platelet-derived growth factor action in vascular smooth muscle cells: a possible role for hydrogen peroxide. Br J Pharmacol. 1997; 122: 269-74.
12. Mudter J, Neurath MF. Apoptosis of T cells and the control of inflammatory bowel disease: therapeutic implications. Gut. 2007; 56: 293-303.
13. Ina K, Itoh J, Fukushima K, et al Resistance of Crohn's disease T cells to multiple apoptotic signals is associated with a Bcl-2/Bax mucosal imbalance. J Immunol. 1999; 163: 1081-90.
14. Zhang C, Cai Y, Adachi MT, et al Homocysteine induces programmed cell death in human vascular endothelial cells through activation of the unfolded protein response. J Biol Chem. 2001; 276: 35867-74.
15. Stevceva L, Pavli P, Husband A, et al Dextran sulphate sodium-induced colitis is ameliorated in interleukin 4 deficient mice. Genes Immun. 2001; 2: 309-16.
16. Cooper HS, Murthy S, Kido K, et al Dysplasia and cancer in the dextran sulfate sodium mouse colitis model. Relevance to colitis-associated neoplasia in the human: a study of histopathology, B-catenin and p53 expression and the role of inflammation. Carcinogenesis. 2000; 21: 757-68.
17. Paglia DE, Valentine WN. Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J Lab Clin Med. 1967; 70: 158-69.
18. Xia Y, Zweier JL. Measurement of myeloperoxidase in leukocyte-containing tissues. Anal Biochem. 1997; 245: 93-6.
19. Katakura K, Lee J, Rachmilewitz D, et al Toll-like receptor 9-induced type I IFN protects mice from experimental colitis. J Clin Invest. 2005; 115: 695-702.
20. Okayasu I, Hatakeyama S, Yamada M, et al A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in mice. Gastroenterology. 1990; 98: 694-702.
21. Melgar S, Karlsson A, Michaelsson E. Acute colitis induced by dextran sulfate sodium progresses to chronicity in C57BL/6 but not in BALB/c mice: correlation between symptoms and inflammation. Am J Physiol Gastrointest Liver Physiol. 2005; 288: G1328-38.
22. Murthy SN, Cooper HS, Shim H, et al Treatment of dextran sulfate sodium-induced murine colitis by intracolonic cyclosporin. Dig Dis Sci. 1993; 38: 1722-34.
23. Borsch-Haubold AG, Ghomashchi F, Pasquet S, et al Phosphorylation of cytosolic phospholipase A2 in platelets is mediated by multiple stress-activated protein kinase pathways. Eur J Biochem. 1999; 265: 195-203.
24. Harizi H, Corcuff JB, Gualde N. Arachidonic-acid-derived eicosanoids: roles in biology and immunopathology. Trends Mol Med. 2008; 14: 461-9.
25. Bossenmeyer-Pourié C, Blaise S, Pourié G, et al Methyl donor deficiency affects fetal programming of gastric ghrelin cell organization and function in the rat. Am J Pathol. 2010; 176: 270-7.
26. Maor I, Rainis T, Lanir A, et al Oxidative stress, inflammation and neutrophil superoxide release in patients with Crohn's disease: distinction between active and non-active disease. Dig Dis Sci. 2008; 53: 2208-14.
27. Handy DE, Zhang Y, Loscalzo J. Homocysteine down-regulates cellular glutathione peroxidase (GPx1) by decreasing translation. J Biol Chem. 2005; 280: 15518-25.
28. Mangiagalli A, Samuele A, Armentero MT, et al Effects of homocysteine on apoptosis-related proteins and anti-oxidant systems in isolated human lymphocytes. Eur J Biochem. 2004; 271: 1671-6.
29. Robert K, Nehme J, Bourdon E, et al Cystathionine beta synthase deficiency promotes oxidative stress, fibrosis, and steatosis in mice liver. Gastroenterology. 2005; 128: 1405-15.
30. Blaise S, Alberto JM, Nedelec E, et al Mild neonatal hypoxia exacerbates the effects of vitamin-deficient diet on homocysteine metabolism in rats. Pediatr Res. 2005; 57: 777-82.
31. Vijayalakshhmi B, Sesikeran B, Udaykumar P, et al Effects of vitamin restriction and supplementation on rat intestinal epithelial cell apoptosis. Free Radic Biol Med. 2005; 38: 1614-24.
32. Mohammed FF, Smookler DS, Taylor SE, et al Abnormal TNF activity in Timp3-/- mice leads to chronic hepatic inflammation and failure of liver regeneration. Nat Genet. 2004; 36: 969-77.
33. Cesaro A, Abakar-Mahamat A, Brest P, et al Differential expression and regulation of ADAM17 and TIMP3 in acute inflamed intestinal epithelia. Am J Physiol Gastrointest Liver Physiol. 2009; 296: G1332-43.
34. Black RA. TIMP3 checks inflammation. Nat Genet. 2004; 36: 934-5.
35. Waetzig GH, Seegert D, Rosenstiel P, et al p38 mitogen-activated protein kinase is activated and linked to TNF-alpha signaling in inflammatory bowel disease. J Immunol. 2002; 168: 5342-51.
36. Kyriakis JM, Avruch J. Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. Physiol Rev. 2001; 81: 807-69.
37. Iimura M, Nakamura T, Shinozaki S, et al Bax is downregulated in inflamed colonic mucosa of ulcerative colitis. Gut. 2000; 47: 228-35.
38. Peracchi M, Bamonti Catena F, et al Human cobalamin deficiency: alterations in serum tumour necrosis factor-alpha and epidermal growth factor. Eur J Haematol. 2001; 67: 123-7.
39. Hsu-Battaglia SF, Akchiche N, Noel N, et al Vitamin B12 deficiency reduces proliferation and promotes differentiation of neuroblastoma cells and upregulates PP2A, proNGF and TACE. Proc Natl Acad Sci USA. 2009; 106: 21930-5.
40. Scalabrino G. The multi-faceted basis of vitamin B12 (cobalamin) neurotrophism in adult central nervous system: lessons learned from its deficiency. Prog Neurobiol. 2009; 88: 203-20.
41. Zemlyak I, Brooke SM, Singh MH, et al Effects of overexpression of antioxidants on the release of cytochrome c and apoptosis-inducing factor in the model of ischemia. Neurosci Lett. 2009; 453: 182-5.
42. Tomita Y, Jyoyama H, Kobayashi M, et al Role of group IIA phospholipase A2 in rat colitis induced by dextran sulfate sodium. Eur J Pharmacol. 2003; 472: 147-58.
43. Minami T, Shinomura Y, Miyagawa J, et al Immunohistochemical localization of group II phospholipase A2 in colonic mucosa of patients with inflammatory bowel disease. Am J Gastroenterol. 1997; 92: 289-92.
44. Krimsky M, Yedgar S, Aptekar L, et al Amelioration of TNBS-induced colon inflammation in rats by phospholipase A2 inhibitor. Am J Physiol Gastrointest Liver Physiol. 2003; 285: G586-92.
45. Singer II, Kawka DW, Schloemann S, et al Cyclooxygenase 2 is induced in colonic epithelial cells in inflammatory bowel disease. Gastroenterology. 1998; 115: 297-306.
46. Hendel J, Nielsen OH. Expression of cyclooxygenase-2 mRNA in active inflammatory bowel disease. Am J Gastroenterol. 1997; 92: 1170-3.
47. Maier JA, Hla T, Maciag T. Cyclooxygenase is an immediate-early gene induced by interleukin-1 in human endothelial cells. J Biol Chem. 1990; 265: 10805-8.
48. Leoncini G, Bruzzese D, Signorello MG. Activation of p38 MAPKinase/cPLA2 pathway in homocysteine-treated platelets. J Thromb Haemost. 2006; 4: 209-16.
49. Fantini MC, Pallone F. Cytokines: from gut inflammation to colorectal cancer. Curr Drug Targets. 2008; 9: 375-80.
50. Van Guelpen B, Hultdin J, Johansson I, et al Low folate levels may protect against colorectal cancer. Gut. 2006; 55: 1461-6.
51. Jang H, Mason JB, Choi SW. Genetic and epigenetic interactions between folate and aging in carcinogenesis. J Nutr. 2005; 135: 2967S-71S.
52. Crott JW, Liu Z, Keyes MK, et al Moderate folate depletion modulates the expression of selected genes involved in cell cycle, intracellular signaling and folate uptake in human colonic epithelial cell lines. J Nutr Biochem. 2008; 19: 328-35.
53. Drzewoski J, Gasiorowska A, Malecka-Panas E, et al Plasma total homocysteine in the active stage of ulcerative colitis. J Gastroenterol Hepatol. 2006; 21: 739-43.
54. Bruewer M, Samarin S, Nusrat A. Inflammatory bowel disease and the apical junctional complex. Ann N Y Acad Sci. 2006; 1072: 242-52.
55. Kucharzik T, Walsh SV, Chen J, et al Neutrophil transmigration in inflammatory bowel disease is associated with differential expression of epithelial intercellular junction proteins. Am J Pathol. 2001; 159: 2001-9.