-
1
-
-
77952316009
-
Inflammatory bowel disease
-
Kaser, A., Zeissig, S., Blumberg, R. S. (2010) Inflammatory bowel disease. Ann. Rev. Immunol. 28, 573-6211
-
(2010)
Ann. Rev. Immunol
, vol.28
, pp. 573-6211
-
-
Kaser, A.1
Zeissig, S.2
Blumberg, R.S.3
-
2
-
-
52649101086
-
Beyond TNF, Th1 and Th2 in inflammatory bowel disease
-
Shale, M., Ghosh, S. (2008) Beyond TNF, Th1 and Th2 in inflammatory bowel disease. Gut. 57, 1349-13511
-
(2008)
Gut
, vol.57
, pp. 1349-13511
-
-
Shale, M.1
Ghosh, S.2
-
3
-
-
10044227057
-
An historical overview of the treatment of Crohn's disease: Why do we need biological therapies?
-
Rutgeerts, P. J. (2004) An historical overview of the treatment of Crohn's disease: why do we need biological therapies? Rev. Gastroenterol. Disord. 4 (Suppl. 3), S3-S91
-
(2004)
Rev. Gastroenterol. Disord
, vol.4
, Issue.SUPPL. 3
-
-
Rutgeerts, P.J.1
-
4
-
-
43049099077
-
Inflammatory bowel disease: A new combination therapy for pouchitis
-
Sandborn, W. J. (2005) Inflammatory bowel disease: a new combination therapy for pouchitis. Rev. Gastroenterol. Disord. 5, 1101
-
(2005)
Rev. Gastroenterol. Disord
, vol.5
, pp. 1101
-
-
Sandborn, W.J.1
-
5
-
-
0037833486
-
Mouse models for the study of Crohn's disease
-
Pizarro, T. T., Arseneau, K. O., Bamias, G., Cominelli, F. (2003) Mouse models for the study of Crohn's disease. Trends Mol. Med. 9, 218-2221
-
(2003)
Trends Mol. Med
, vol.9
, pp. 218-2221
-
-
Pizarro, T.T.1
Arseneau, K.O.2
Bamias, G.3
Cominelli, F.4
-
6
-
-
0036218221
-
The immunology of mucosal models of inflammation
-
Strober, W., Fuss, I. J., Blumberg, R. S. (2002) The immunology of mucosal models of inflammation. Ann. Rev. Immunol. 20, 495-5491
-
(2002)
Ann. Rev. Immunol
, vol.20
, pp. 495-5491
-
-
Strober, W.1
Fuss, I.J.2
Blumberg, R.S.3
-
7
-
-
13944281011
-
Expression of interleukin- 12-related cytokine transcripts in inflammatory bowel disease: Elevated interleukin-23p19 and interleukin-27p28 in Crohn's disease but not in ulcerative colitis
-
Schmidt, C., Giese, T., Ludwig, B., Mueller-Molaian, I., Marth, T., Zeuzem, S., Meuer, S. C., Stallmach, A. (2005) Expression of interleukin- 12-related cytokine transcripts in inflammatory bowel disease: elevated interleukin-23p19 and interleukin-27p28 in Crohn's disease but not in ulcerative colitis. Inflamm. Bowel Dis. 11, 16-231
-
(2005)
Inflamm. Bowel Dis
, vol.11
, pp. 16-231
-
-
Schmidt, C.1
Giese, T.2
Ludwig, B.3
Mueller-Molaian, I.4
Marth, T.5
Zeuzem, S.6
Meuer, S.C.7
Stallmach, A.8
-
8
-
-
0034600789
-
Treatment of experimental (trinitrobenzene sulfonic acid) colitis by intranasal administration of transforming growth factor (TGF)-β1 plasmid: TGF- β1-mediated suppression of T helper cell type 1 response occurs by interleukin (IL)-10 induction and IL-12 receptor β2 chain downregulation
-
Kitani, A., Fuss, I. J., Nakamura, K., Schwartz, O. M., Usui, T., Strober, W. (2000) Treatment of experimental (trinitrobenzene sulfonic acid) colitis by intranasal administration of transforming growth factor (TGF)-β1 plasmid: TGF- β1-mediated suppression of T helper cell type 1 response occurs by interleukin (IL)-10 induction and IL-12 receptor β2 chain downregulation. J. Exp. Med. 192, 41-521
-
(2000)
J. Exp. Med
, vol.192
, pp. 41-521
-
-
Kitani, A.1
Fuss, I.J.2
Nakamura, K.3
Schwartz, O.M.4
Usui, T.5
Strober, W.6
-
9
-
-
0035806290
-
Identification and functional characterization of human CD4(+)CD25(+) T cells with regulatory properties isolated from peripheral blood
-
Jonuleit, H., Schmitt, E., Stassen, M., Tuettenberg, A., Knop, J., Enk, A. H. (2001) Identification and functional characterization of human CD4(+)CD25(+) T cells with regulatory properties isolated from peripheral blood. J. Exp. Med. 193, 1285-12941
-
(2001)
J. Exp. Med
, vol.193
, pp. 1285-12941
-
-
Jonuleit, H.1
Schmitt, E.2
Stassen, M.3
Tuettenberg, A.4
Knop, J.5
Enk, A.H.6
-
10
-
-
0037385330
-
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
-
Fontenot, J. D., Gavin, M. A., Rudensky, A. Y. (2003) Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat. Immunol. 4, 330-3361
-
(2003)
Nat. Immunol
, vol.4
, pp. 330-3361
-
-
Fontenot, J.D.1
Gavin, M.A.2
Rudensky, A.Y.3
-
11
-
-
0347785480
-
Control of regulatory T cell development by the transcription factor Foxp3
-
Hori, S., Nomura, T., Sakaguchi, S. (2003) Control of regulatory T cell development by the transcription factor Foxp3. Science 299, 1057-10611
-
(2003)
Science
, vol.299
, pp. 1057-10611
-
-
Hori, S.1
Nomura, T.2
Sakaguchi, S.3
-
12
-
-
0037385314
-
An essential role for Scurfin in CD4+CD25+T regulatory cells
-
Khattri, R., Cox, T., Yasayko, S. A., Ramsdell, F. (2003) An essential role for Scurfin in CD4+CD25+T regulatory cells. Nat. Immunol. 4, 337-3421
-
(2003)
Nat. Immunol
, vol.4
, pp. 337-3421
-
-
Khattri, R.1
Cox, T.2
Yasayko, S.A.3
Ramsdell, F.4
-
13
-
-
0036346861
-
Clinical and molecular features of the immunodysregulation, polyendocrinopathy, enteropathy, X linked (IPEX) syndrome
-
Wildin, R. S., Smyk-Pearson, S., Filipovich, A. H. (2002) Clinical and molecular features of the immunodysregulation, polyendocrinopathy, enteropathy, X linked (IPEX) syndrome. J. Med. Genet. 39, 537-5451
-
(2002)
J. Med. Genet
, vol.39
, pp. 537-5451
-
-
Wildin, R.S.1
Smyk-Pearson, S.2
Filipovich, A.H.3
-
14
-
-
33947644716
-
Cutting edge: IL-2 is essential for TGF-β-mediated induction of Foxp3β T regulatory cells
-
Davidson, T. S., DiPaolo, R. J., Andersson, J., Shevach, E. M. (2007) Cutting edge: IL-2 is essential for TGF-β-mediated induction of Foxp3β T regulatory cells. J. Immunol. 178, 4022-40261
-
(2007)
J. Immunol
, vol.178
, pp. 4022-40261
-
-
Davidson, T.S.1
Dipaolo, R.J.2
Andersson, J.3
Shevach, E.M.4
-
15
-
-
34548733134
-
A Kinetic and Dynamic Analysis of Foxp3 Induced In T Cells By TGF- β
-
following 13901
-
Selvaraj, R. K., Geiger, T. L. (2007) A kinetic and dynamic analysis of Foxp3 induced in T cells by TGF- β. J. Immunol. 179, 11 p following 13901
-
(2007)
J. Immuno
, vol.179
, pp. 11
-
-
Selvaraj, R.K.1
Geiger, T.L.2
-
16
-
-
38949164425
-
Retinoic acid inhibits Th17 polarization and enhances FoxP3 expression through a Stat-3/Stat-5 independent signaling pathway
-
Elias, K. M., Laurence, A., Davidson, T. S., Stephens, G., Kanno, Y., Shevach, E. M., O'Shea, J. J. (2008) Retinoic acid inhibits Th17 polarization and enhances FoxP3 expression through a Stat-3/Stat-5 independent signaling pathway. Blood 111, 1013-10201
-
(2008)
Blood
, vol.111
, pp. 1013-10201
-
-
Elias, K.M.1
Laurence, A.2
Davidson, T.S.3
Stephens, G.4
Kanno, Y.5
Shevach, E.M.6
O'Shea, J.J.7
-
17
-
-
47249141222
-
Anti-inflammatory effects of FTY720 against viral-induced immunopathology: Role of drug-induced conversion of T cells to become Foxp3β regulators
-
Sehrawat, S., Rouse, B. T. (2008) Anti-inflammatory effects of FTY720 against viral-induced immunopathology: role of drug-induced conversion of T cells to become Foxp3β regulators. J. Immunol. 180, 7636-76471
-
(2008)
J. Immunol
, vol.180
, pp. 7636-76471
-
-
Sehrawat, S.1
Rouse, B.T.2
-
18
-
-
33644896206
-
Effects of a novel tylophorine analog on collagen-induced arthritis through inhibition of the innate immune response
-
You, X., Pan, M., Gao, W., Shiah, H. S., Tao, J., Zhang, D., Koumpouras, F., Wang, S., Zhao, H., Madri, J. A., Baker, D., Cheng, Y. C., Yin, Z. (2006) Effects of a novel tylophorine analog on collagen-induced arthritis through inhibition of the innate immune response. Arthritis Rheum. 54, 877-8861
-
(2006)
Arthritis Rheum
, vol.54
, pp. 877-8861
-
-
You, X.1
Pan, M.2
Gao, W.3
Shiah, H.S.4
Tao, J.5
Zhang, D.6
Koumpouras, F.7
Wang, S.8
Zhao, H.9
Madri, J.A.10
Baker, D.11
Cheng, Y.C.12
Yin, Z.13
-
19
-
-
0034653471
-
Dominance of IL-12 over IL-4 in γ δ T cell differentiation leads to default production of IFN- γ: Failure to down-regulate IL-12 receptorβ2-chain expression
-
Yin, Z., Zhang, D. H., Welte, T., Bahtiyar, G., Jung, S., Liu, L., Fu, X. Y., Ray, A., Craft, J. (2000) Dominance of IL-12 over IL-4 in γ δ T cell differentiation leads to default production of IFN- γ: failure to down-regulate IL-12 receptorβ2-chain expression. J. Immunol. 164, 3056-30641
-
(2000)
J. Immunol
, vol.164
, pp. 3056-30641
-
-
Yin, Z.1
Zhang, D.H.2
Welte, T.3
Bahtiyar, G.4
Jung, S.5
Liu, L.6
Fu, X.Y.7
Ray, A.8
Craft, J.9
-
20
-
-
70349635629
-
All-trans retinoic acid down-regulates inflammatory responses by shifting the Treg/ Th17 profile in human ulcerative and murine colitis
-
Bai, A., Lu, N., Guo, Y., Liu, Z., Chen, J., Peng, Z. (2009) All-trans retinoic acid down-regulates inflammatory responses by shifting the Treg/ Th17 profile in human ulcerative and murine colitis. J. Leukoc. Biol. 86, 959-9691
-
(2009)
J. Leukoc. Biol
, vol.86
, pp. 959-9691
-
-
Bai, A.1
Lu, N.2
Guo, Y.3
Liu, Z.4
Chen, J.5
Peng, Z.6
-
21
-
-
33750049009
-
Interferon-γ is causatively involved in experimental inflammatory bowel disease in mice
-
Ito, R., Shin-Ya, M., Kishida, T., Urano, A., Takada, R., Sakagami, J., Imanishi, J., Kita, M., Ueda, Y., Iwakura, Y., Kataoka, K., Okanoue, T., Mazda, O. (2006) Interferon-γ is causatively involved in experimental inflammatory bowel disease in mice. Clin. Exp. Immunol. 146, 330-3381
-
(2006)
Clin. Exp. Immunol
, vol.146
, pp. 330-3381
-
-
Ito, R.1
Shin-Ya, M.2
Kishida, T.3
Urano, A.4
Takada, R.5
Sakagami, J.6
Imanishi, J.7
Kita, M.8
Ueda, Y.9
Iwakura, Y.10
Kataoka, K.11
Okanoue, T.12
Mazda, O.13
-
22
-
-
38449084962
-
Isolation and subsequent analysis of murine lamina propria mononuclear cells from colonic tissue
-
Weigmann, B., Tubbe, I., Seidel, D., Nicolaev, A., Becker, C., Neurath, M. F. (2007) Isolation and subsequent analysis of murine lamina propria mononuclear cells from colonic tissue. Nat. Protoc. 2, 2307-23111
-
(2007)
Nat. Protoc
, vol.2
, pp. 2307-23111
-
-
Weigmann, B.1
Tubbe, I.2
Seidel, D.3
Nicolaev, A.4
Becker, C.5
Neurath, M.F.6
-
23
-
-
72149124496
-
Smad3 differentially regulates the induction of regulatory and inflammatory T cell differentiation
-
Martinez, G. J., Zhang, Z., Chung, Y., Reynolds, J. M., Lin, X., Jetten, A. M., Feng, X. H., Dong, C. (2009) Smad3 differentially regulates the induction of regulatory and inflammatory T cell differentiation. J. Biol. Chem. 284, 35283-352861
-
(2009)
J. Biol. Chem
, vol.284
, pp. 35283-352861
-
-
Martinez, G.J.1
Zhang, Z.2
Chung, Y.3
Reynolds, J.M.4
Lin, X.5
Jetten, A.M.6
Feng, X.H.7
Dong, C.8
-
24
-
-
30444434212
-
Novel roles of Akt and mTOR in suppressing TGF-β/ALK5-mediated Smad3 activation
-
Song, K., Wang, H., Krebs, T. L., Danielpour, D. (2006) Novel roles of Akt and mTOR in suppressing TGF-_/ALK5-mediated Smad3 activation. EMBO J. 25, 58-691
-
(2006)
EMBO J
, vol.25
, pp. 58-691
-
-
Song, K.1
Wang, H.2
Krebs, T.L.3
Danielpour, D.4
-
25
-
-
0141532196
-
Insulin-like growth factor-I inhibits transcriptional responses of transforming growth factor-I by phosphatidylinositol 3-kinase/Akt-dependent suppression of the activation of Smad3 but not Smad2
-
Song, K., Cornelius, S. C., Reiss, M., Danielpour, D. (2003) Insulin-like growth factor-I inhibits transcriptional responses of transforming growth factor-I by phosphatidylinositol 3-kinase/Akt-dependent suppression of the activation of Smad3 but not Smad2. J. Biol. Chem. 278, 38342-383511
-
(2003)
J. Biol. Chem
, vol.278
, pp. 38342-383511
-
-
Song, K.1
Cornelius, S.C.2
Reiss, M.3
Danielpour, D.4
-
26
-
-
74949129499
-
Decreased ERK and JNK signaling contribute to gene overexpression in "senescent" CD4+CD28-T cells through epigenetic mechanisms
-
Chen, Y., Gorelik, G. J., Strickland, F. M., Richardson, B. C. (2010) Decreased ERK and JNK signaling contribute to gene overexpression in "senescent" CD4+CD28-T cells through epigenetic mechanisms. J. Leukoc. Biol. 87, 137-1451
-
(2010)
J. Leukoc. Biol
, vol.87
, pp. 137-1451
-
-
Chen, Y.1
Gorelik, G.J.2
Strickland, F.M.3
Richardson, B.C.4
-
27
-
-
79954989313
-
Atorvastatin upregulates regulatory T cells and reduces clinical disease activity in patients with rheumatoid arthritis
-
Tang, T. T., Song, Y., Ding, Y. J., Liao, Y. H., Yu, X., Du, R., Xiao, H., Yuan, J., Zhou, Z. H., Liao, M. Y., Yao, R., Jevallee, H., Shi, G. P., Cheng, X. (2011) Atorvastatin upregulates regulatory T cells and reduces clinical disease activity in patients with rheumatoid arthritis. J. Lipid Res. 52, 1023-10321
-
(2011)
J. Lipid Res
, vol.52
, pp. 1023-10321
-
-
Tang, T.T.1
Song, Y.2
Ding, Y.J.3
Liao, Y.H.4
Yu, X.5
Du, R.6
Xiao, H.7
Yuan, J.8
Zhou, Z.H.9
Liao, M.Y.10
Yao, R.11
Jevallee, H.12
Shi, G.P.13
Cheng, X.14
-
28
-
-
70349249977
-
Dynamics of peripheral tolerance and immune regulation mediated by Treg
-
Sakaguchi, S., Wing, K., Yamaguchi, T. (2009) Dynamics of peripheral tolerance and immune regulation mediated by Treg. Eur. J. Immunol. 39, 2331-23361
-
(2009)
Eur. J. Immunol
, vol.39
, pp. 2331-23361
-
-
Sakaguchi, S.1
Wing, K.2
Yamaguchi, T.3
-
29
-
-
56649091213
-
Role of TGF-β in the induction of Foxp3 expression and T regulatory cell function
-
Shevach, E. M., Davidson, T. S., Huter, E. N., Dipaolo, R. A., Andersson, J. (2008) Role of TGF-β in the induction of Foxp3 expression and T regulatory cell function. J. Clin. Immunol. 28, 640-6461
-
(2008)
J. Clin. Immunol
, vol.28
, pp. 640-6461
-
-
Shevach, E.M.1
Davidson, T.S.2
Huter, E.N.3
Dipaolo, R.A.4
Andersson, J.5
-
30
-
-
33847651713
-
Thymic development and peripheral homeostasis of regulatory T cells
-
Liston, A., Rudensky, A. Y. (2007) Thymic development and peripheral homeostasis of regulatory T cells. Curr. Opin. Immunol. 19, 176-1851
-
(2007)
Curr. Opin. Immunol
, vol.19
, pp. 176-1851
-
-
Liston, A.1
Rudensky, A.Y.2
-
31
-
-
33846485153
-
Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice
-
Kim, J. M., Rasmussen, J. P., Rudensky, A. Y. (2007) Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice. Nat. Immunol. 8, 191-1971
-
(2007)
Nat. Immunol
, vol.8
, pp. 191-1971
-
-
Kim, J.M.1
Rasmussen, J.P.2
Rudensky, A.Y.3
-
32
-
-
49849094011
-
Natural and TGF-β-induced Foxp3(+)CD4(+) CD25(+) regulatory T cells are not mirror images of each other
-
Horwitz, D. A., Zheng, S. G., Gray, J. D. (2008) Natural and TGF-_-induced Foxp3(+)CD4(+) CD25(+) regulatory T cells are not mirror images of each other. Trends Immunol. 29, 429-4351
-
(2008)
Trends Immunol
, vol.29
, pp. 429-4351
-
-
Horwitz, D.A.1
Zheng, S.G.2
Gray, J.D.3
-
33
-
-
33644845305
-
Antiinflammatory mechanisms of phenanthroindolizidine alkaloids
-
Yang, C. W., Chen, W. L., Wu, P. L., Tseng, H. Y., Lee, S. J. (2006) Antiinflammatory mechanisms of phenanthroindolizidine alkaloids. Mol. Pharmacol. 69, 749-7581
-
(2006)
Mol. Pharmacol
, vol.69
, pp. 749-7581
-
-
Yang, C.W.1
Chen, W.L.2
Wu, P.L.3
Tseng, H.Y.4
Lee, S.J.5
-
34
-
-
77958153961
-
Identification of phenanthroindolizines and phenanthroquinolizidines as novel potent anti-coronaviral agents for porcine enteropathogenic coronavirus transmissible gastroenteritis virus and human severe acute respiratory syndrome coronavirus
-
Yang, C. W., Lee, Y. Z., Kang, I. J., Barnard, D. L., Jan, J. T., Lin, D., Huang, C. W., Yeh, T. K., Chao, Y. S., Lee, S. J. (2010) Identification of phenanthroindolizines and phenanthroquinolizidines as novel potent anti-coronaviral agents for porcine enteropathogenic coronavirus transmissible gastroenteritis virus and human severe acute respiratory syndrome coronavirus. Antiviral Res. 88, 160-1681
-
(2010)
Antiviral Res
, vol.88
, pp. 160-1681
-
-
Yang, C.W.1
Lee, Y.Z.2
Kang, I.J.3
Barnard, D.L.4
Jan, J.T.5
Lin, D.6
Huang, C.W.7
Yeh, T.K.8
Chao, Y.S.9
Lee, S.J.10
-
35
-
-
1642475128
-
Novel mode of action of tylophorine analogs as antitumor compounds
-
Gao, W., Lam, W., Zhong, S., Kaczmarek, C., Baker, D. C., Cheng, Y. C. (2004) Novel mode of action of tylophorine analogs as antitumor compounds. Cancer Res. 64, 678-6881
-
(2004)
Cancer Res
, vol.64
, pp. 678-6881
-
-
Gao, W.1
Lam, W.2
Zhong, S.3
Kaczmarek, C.4
Baker, D.C.5
Cheng, Y.C.6
-
36
-
-
84865635857
-
Therapeutic effects of a novel tylophorine analog NK-007 on collagen-induced arthritis through suppressing TNF-αproduction and Th17 differentiation
-
Wen, T., Li, Y., Wu, M., Sun, X., Bao, X., Lin, Y., Hao, J., Han, L., Cao, G., Wang, Z., Liu, Y., Wu, Z., Hong, Z., Wang, P., Zhao, L., Li, Z., Wang, Q., Yin, Z. (2012) Therapeutic effects of a novel tylophorine analog NK- 007 on collagen-induced arthritis through suppressing TNF-_ production and Th17 differentiation. Arthritis Rheum. 64, 2896-29061
-
(2012)
Arthritis Rheum
, vol.64
, pp. 2896-29061
-
-
Wen, T.1
Li, Y.2
Wu, M.3
Sun, X.4
Bao, X.5
Lin, Y.6
Hao, J.7
Han, L.8
Cao, G.9
Wang, Z.10
Liu, Y.11
Wu, Z.12
Hong, Z.13
Wang, P.14
Zhao, L.15
Li, Z.16
Wang, Q.17
Yin, Z.18
-
37
-
-
84866987866
-
A novel tylophorine analog NK-007 ameliorates colitis through inhibition of innate immune response
-
Wen, T., Li, Y., Wu, M., Chen, X., Han, L., Bao, X., Wang, Z., Wang, K., Hu, Y., Zhou, X., Wu, Z., Wang, P., Hong, Z., Zhao, L., Wang, Q., Yin, Z. (2012) A novel tylophorine analog NK-007 ameliorates colitis through inhibition of innate immune response. Int. Immunopharmacol. 14, 487-4941
-
(2012)
Int. Immunopharmacol
, vol.14
, pp. 487-4941
-
-
Wen, T.1
Li, Y.2
Wu, M.3
Chen, X.4
Han, L.5
Bao, X.6
Wang, Z.7
Wang, K.8
Hu, Y.9
Zhou, X.10
Wu, Z.11
Wang, P.12
Hong, Z.13
Zhao, L.14
Wang, Q.15
Yin, Z.16
-
38
-
-
77952777819
-
Role of SMAD and non-SMAD signals in the development of Th17 and regulatory T cells
-
Lu, L., Wang, J., Zhang, F., Chai, Y., Brand, D., Wang, X., Horwitz, D. A., Shi, W., Zheng, S. G. (2010) Role of SMAD and non-SMAD signals in the development of Th17 and regulatory T cells. J. Immunol. 184, 4295-43061
-
(2010)
J. Immunol
, vol.184
, pp. 4295-43061
-
-
Lu, L.1
Wang, J.2
Zhang, F.3
Chai, Y.4
Brand, D.5
Wang, X.6
Horwitz, D.A.7
Shi, W.8
Zheng, S.G.9
-
39
-
-
0345832090
-
Activation of the pro-survival phosphatidylinositol 3-kinase/AKT pathway by transforming growth factor- α1 in mesenchymal cells is mediated by p38 MAPK-dependent induction of an autocrine growth factor
-
Horowitz, J. C., Lee, D. Y., Waghray, M., Keshamouni, V. G., Thomas, P. E., Zhang, H., Cui, Z., Thannickal, V. J. (2004) Activation of the pro-survival phosphatidylinositol 3-kinase/AKT pathway by transforming growth factor- _1 in mesenchymal cells is mediated by p38 MAPK-dependent induction of an autocrine growth factor. J. Biol. Chem. 279, 1359-13671
-
(2004)
J. Biol. Chem
, vol.279
, pp. 1359-13671
-
-
Horowitz, J.C.1
Lee, D.Y.2
Waghray, M.3
Keshamouni, V.G.4
Thomas, P.E.5
Zhang, H.6
Cui, Z.7
Thannickal, V.J.8
-
40
-
-
2342471301
-
Akt interacts directly with Smad3 to regulate the sensitivity to TGF-β induced apoptosis
-
Conery, A. R., Cao, Y., Thompson, E. A., Townsend C. M., Jr., Ko, T. C., Luo, K. (2004) Akt interacts directly with Smad3 to regulate the sensitivity to TGF-_ induced apoptosis. Nat. Cell Biol. 6, 366-3721
-
(2004)
Nat. Cell Biol
, vol.6
, pp. 366-3721
-
-
Conery, A.R.1
Cao, Y.2
Thompson, E.A.3
Townsend Jr., C.M.4
Ko, T.C.5
Luo, K.6
-
41
-
-
79956294973
-
DNA methylation and demethylation in mammals
-
Chen, Z. X., Riggs, A. D. (2011) DNA methylation and demethylation in mammals. J. Biol. Chem. 286, 18347-183531
-
(2011)
J. Biol. Chem
, vol.286
, pp. 18347-183531
-
-
Chen, Z.X.1
Riggs, A.D.2
-
42
-
-
45449114804
-
The colorful history of active DNA demethylation
-
Ooi, S. K., Bestor, T. H. (2008) The colorful history of active DNA demethylation. Cell 133, 1145-11481
-
(2008)
Cell
, vol.133
, pp. 1145-11481
-
-
Ooi, S.K.1
Bestor, T.H.2
-
43
-
-
78650642538
-
Peroxisome proliferator-activated receptor αand γagonists together with TGF-αconvert human CD4+CD25-T cells into functional Foxp3+ regulatory T cells
-
Lei, J., Hasegawa, H., Matsumoto, T., Yasukawa, M. (2010) Peroxisome proliferator-activated receptor _ and _ agonists together with TGF-_ convert human CD4+CD25-T cells into functional Foxp3+ regulatory T cells. J. Immunol. 185, 7186-71981
-
(2010)
J. Immunol
, vol.185
, pp. 7186-71981
-
-
Lei, J.1
Hasegawa, H.2
Matsumoto, T.3
Yasukawa, M.4
-
44
-
-
77954497611
-
Simvastatin induces Foxp3+T regulatory cells by modulation of transforming growth factor- α signal transduction
-
Kim, Y. C., Kim, K. K., Shevach, E. M. (2010) Simvastatin induces Foxp3+T regulatory cells by modulation of transforming growth factor- _ signal transduction. Immunology 130, 484-4931
-
(2010)
Immunology
, vol.130
, pp. 484-4931
-
-
Kim, Y.C.1
Kim, K.K.2
Shevach, E.M.3
-
45
-
-
0037333972
-
Hydralazine may induce autoimmunity by inhibiting extracellular signal-regulated kinase pathway signaling
-
Deng, C., Lu, Q., Zhang, Z., Rao, T., Attwood, J., Yung, R., Richardson, B. (2003) Hydralazine may induce autoimmunity by inhibiting extracellular signal-regulated kinase pathway signaling. Arthritis Rheum. 48, 746-7561
-
(2003)
Arthritis Rheum
, vol.48
, pp. 746-7561
-
-
Deng, C.1
Lu, Q.2
Zhang, Z.3
Rao, T.4
Attwood, J.5
Yung, R.6
Richardson, B.7
-
46
-
-
18644376210
-
Demethylation of the same promoter sequence increases CD70 expression in lupus T cells and T cells treated with lupus-inducing drugs
-
Lu, Q., Wu, A., Richardson, B. C. (2005) Demethylation of the same promoter sequence increases CD70 expression in lupus T cells and T cells treated with lupus-inducing drugs. J. Immunol. 174, 6212-62191
-
(2005)
J. Immunol
, vol.174
, pp. 6212-62191
-
-
Lu, Q.1
Wu, A.2
Richardson, B.C.3
-
47
-
-
0033029507
-
The role of CTLA-4 in the regulation of T cell immune responses
-
McCoy, K. D., Le Gros, G. (1999) The role of CTLA-4 in the regulation of T cell immune responses. Immunol. Cell Biol. 77, 1-101
-
(1999)
Immunol. Cell Biol
, vol.77
, pp. 1-101
-
-
McCoy, K.D.1
Le Gros, G.2
-
48
-
-
42649125225
-
PD-1 and its ligands in tolerance and immunity
-
Keir, M. E., Butte, M. J., Freeman, G. J., Sharpe, A. H. (2008) PD-1 and its ligands in tolerance and immunity. Ann. Rev. Immunol. 26, 677-7041
-
(2008)
Ann. Rev. Immunol
, vol.26
, pp. 677-7041
-
-
Keir, M.E.1
Butte, M.J.2
Freeman, G.J.3
Sharpe, A.H.4
-
49
-
-
37249063841
-
TNFα blockade in human diseases: An overview of efficacy and safety
-
Lin, J., Ziring, D., Desai, S., Kim, S., Wong, M., Korin, Y., Braun, J., Reed, E., Gjertson, D., Singh, R. R. (2008) TNF blockade in human diseases: an overview of efficacy and safety. Clin. Immunol. 126, 13-30.
-
(2008)
Clin. Immunol
, vol.126
, pp. 13-30
-
-
Lin, J.1
Ziring, D.2
Desai, S.3
Kim, S.4
Wong, M.5
Korin, Y.6
Braun, J.7
Reed, E.8
Gjertson, D.9
Singh, R.R.10
|