Sphingosine kinase-1 inhibition protects primary rat hepatocytes against bile salt-induced apoptosis

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1832, Issue 12, 2013, Pages 1922-1929

  Karimian, Golnar ^a   Buist Homan, Manon ^a   Schmidt, Martina ^a   Tietge, Uwe J F ^a   de Boer, Jan Freark ^a   Klappe, Karin ^a   Kok, Jan Willem ^a   Combettes, Laurent ^b   Tordjmann, Thierry ^b   Faber, Klaas Nico ^a   Moshage, Han ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b INSERM   (France)

Author keywords

Calcium oscillation; Cholestatic liver disease; Glycochenodeoxycholic acid; Sphingosine kinase; Sphingosine 1 phosphate; Sphingosine 1 phosphate receptor

Indexed keywords

CALCIUM ION; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; GLYCOCHENODEOXYCHOLIC ACID; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE C; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE KINASE 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CALCIUM SIGNALING; CELL PROTECTION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; GENETIC TRANSCRIPTION; LIVER CELL; MALE; NECROSIS; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT;

EID: 84882760512     PISSN: 09254439     EISSN: 1879260X     Source Type: Journal    
DOI: 10.1016/j.bbadis.2013.06.011     Document Type: Article

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