Down-regulation of S1P1 receptor surface expression by protein kinase C inhibition

Journal of Biological Chemistry

Volumn 285, Issue 9, 2010, Pages 6298-6307

  Sensken, Sven Christian ^a   Gräler, Markus H ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTIVE IMMUNITY; CELL-BASED; CELLULAR TARGETS; CONCENTRATION-DEPENDENT; DEGRADING ENZYMES; DOWN-REGULATION; IN-VIVO; LYMPH NODE; LYMPHOCYTE EGRESS; LYMPHOID ORGANS; LYMPHOPENIA; NANOMOLAR CONCENTRATION; NATURAL ANALOG; PHORBOL 12 MYRISTATE 13 ACETATES; PRE-INCUBATION; PROTEIN KINASE C; RECEPTOR CELLS; RECEPTOR SURFACE; SPHINGOSINE; SPHINGOSINE 1 PHOSPHATES; SPLENOCYTES; STAUROSPORINES; SURFACE EXPRESSION; UNDERLYING MECHANISM;

BIOCHEMISTRY; BODY FLUIDS; CELL MEMBRANES; CHEMICAL ACTIVATION; PROTEINS;

ENZYME INHIBITION;

2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; CALPHOSTIN C; FINGOLIMOD; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C; SPHINGOSINE 1 PHOSPHATE RECEPTOR; SPHINGOSINE 1 PHOSPHATE RECEPTOR 1; SPHINGOSINE 1 PHOSPHATE RECEPTOR 4; STAUROSPORINE; UNCLASSIFIED DRUG; PROTEIN KINASE INHIBITOR; SPHINGOSINE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL STIMULATION; CHEMOTAXIS; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFICACY; ENZYME ACTIVATION; ENZYME INHIBITION; GENETIC TRANSFECTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPLEEN CELL; ANIMAL; CELL CULTURE; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; IMMUNITY; LYMPHOCYTOPENIA; RAT; SPLEEN;

MUS; RATTUS;

ANIMALS; CELLS, CULTURED; DOWN-REGULATION; IMMUNITY; LYMPHOPENIA; MICE; PROTEIN KINASE C; PROTEIN KINASE INHIBITORS; RATS; RECEPTORS, LYSOSPHINGOLIPID; SPHINGOSINE; SPLEEN;

EID: 77949876964     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.049692     Document Type: Article

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