메뉴 건너뛰기




Volumn 40, Issue 8, 2013, Pages 375-390

Lipidomics as a Principal Tool for Advancing Biomedical Research

Author keywords

Infectious diseases; Lipidomics; Mass spectrometry; Metabolic syndrome; Neurodegenerative diseases

Indexed keywords

CERAMIDE; CHOLESTEROL; LIPID; LIPIDOME; PHOSPHATIDYLETHANOLAMINE; PHOSPHOLIPASE A2; PHOSPHOLIPASE A2 GAMMA; PHOSPHOLIPASE D2; PHOSPHOLIPID; PHOSPHORUS 32; UNCLASSIFIED DRUG;

EID: 84882257775     PISSN: 16738527     EISSN: 18735533     Source Type: Journal    
DOI: 10.1016/j.jgg.2013.06.007     Document Type: Review
Times cited : (103)

References (132)
  • 3
    • 33750310241 scopus 로고    scopus 로고
    • Genetic disorders of adipose tissue development, differentiation, and death
    • Agarwal A.K., Garg A. Genetic disorders of adipose tissue development, differentiation, and death. Annu. Rev. Genomics Hum. Genet. 2006, 7:175-199.
    • (2006) Annu. Rev. Genomics Hum. Genet. , vol.7 , pp. 175-199
    • Agarwal, A.K.1    Garg, A.2
  • 4
    • 0027325411 scopus 로고
    • Lipid composition and fluidity of the human immunodeficiency virus envelope and host cell plasma membranes
    • Aloia R.C., Tian H., Jensen F.C. Lipid composition and fluidity of the human immunodeficiency virus envelope and host cell plasma membranes. Proc. Natl. Acad. Sci. USA 1993, 90:5181-5185.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 5181-5185
    • Aloia, R.C.1    Tian, H.2    Jensen, F.C.3
  • 6
    • 0030867130 scopus 로고    scopus 로고
    • Biosynthesis of phosphatidic acid in lipid particles and endoplasmic reticulum of Saccharomyces cerevisiae
    • Athenstaedt K., Daum G. Biosynthesis of phosphatidic acid in lipid particles and endoplasmic reticulum of Saccharomyces cerevisiae. J. Bacteriol. 1997, 179:7611-7616.
    • (1997) J. Bacteriol. , vol.179 , pp. 7611-7616
    • Athenstaedt, K.1    Daum, G.2
  • 7
    • 0025094319 scopus 로고
    • An essential role for a phospholipid transfer protein in yeast Golgi function
    • Bankaitis V.A., Aitken J.R., Cleves A.E., Dowhan W. An essential role for a phospholipid transfer protein in yeast Golgi function. Nature 1990, 347:561-562.
    • (1990) Nature , vol.347 , pp. 561-562
    • Bankaitis, V.A.1    Aitken, J.R.2    Cleves, A.E.3    Dowhan, W.4
  • 9
    • 43549104227 scopus 로고    scopus 로고
    • Statins reduce neuronal alpha-synuclein aggregation in invitro models of Parkinson's disease
    • Bar-On P., Crews L., Koob A.O., Mizuno H., Adame A., Spencer B., Masliah E. Statins reduce neuronal alpha-synuclein aggregation in invitro models of Parkinson's disease. J. Neurochem. 2008, 105:1656-1667.
    • (2008) J. Neurochem. , vol.105 , pp. 1656-1667
    • Bar-On, P.1    Crews, L.2    Koob, A.O.3    Mizuno, H.4    Adame, A.5    Spencer, B.6    Masliah, E.7
  • 12
    • 35648995880 scopus 로고    scopus 로고
    • SLC1 and SLC4 encode partially redundant acyl-coenzyme A 1-acylglycerol-3-phosphate O-acyltransferases of budding yeast
    • Benghezal M., Roubaty C., Veepuri V., Knudsen J., Conzelmann A. SLC1 and SLC4 encode partially redundant acyl-coenzyme A 1-acylglycerol-3-phosphate O-acyltransferases of budding yeast. J. Biol. Chem. 2007, 282:30845-30855.
    • (2007) J. Biol. Chem. , vol.282 , pp. 30845-30855
    • Benghezal, M.1    Roubaty, C.2    Veepuri, V.3    Knudsen, J.4    Conzelmann, A.5
  • 16
    • 33646451063 scopus 로고    scopus 로고
    • Elevated levels of oxidized cholesterol metabolites in Lewy body disease brains accelerate alpha-synuclein fibrilization
    • Bosco D.A., Fowler D.M., Zhang Q., Nieva J., Powers E.T., Wentworth P., Lerner R.A., Kelly J.W. Elevated levels of oxidized cholesterol metabolites in Lewy body disease brains accelerate alpha-synuclein fibrilization. Nat. Chem. Biol. 2006, 2:249-253.
    • (2006) Nat. Chem. Biol. , vol.2 , pp. 249-253
    • Bosco, D.A.1    Fowler, D.M.2    Zhang, Q.3    Nieva, J.4    Powers, E.T.5    Wentworth, P.6    Lerner, R.A.7    Kelly, J.W.8
  • 17
    • 70449560405 scopus 로고    scopus 로고
    • The influence of bacterial diet on fat storage in C. elegans
    • Brooks K.K., Liang B., Watts J.L. The influence of bacterial diet on fat storage in C. elegans. PloS ONE 2009, 4:e7545.
    • (2009) PloS ONE , vol.4
    • Brooks, K.K.1    Liang, B.2    Watts, J.L.3
  • 18
    • 0030962474 scopus 로고    scopus 로고
    • Quantitative analysis of biological membrane lipids at the low picomole level by nano-electrospray ionization tandem mass spectrometry
    • Brügger B., Erben G., Sandhoff R., Wieland F.T., Lehmann W.D. Quantitative analysis of biological membrane lipids at the low picomole level by nano-electrospray ionization tandem mass spectrometry. Proc. Natl. Acad. Sci. USA 1997, 94:2339-2344.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 2339-2344
    • Brügger, B.1    Erben, G.2    Sandhoff, R.3    Wieland, F.T.4    Lehmann, W.D.5
  • 23
    • 55549118226 scopus 로고    scopus 로고
    • Retroviruses human immunodeficiency virus and murine leukemia virus are enriched in phosphoinositides
    • Chan R., Uchil P.D., Jin J., Shui G., Ott D.E., Mothes W., Wenk M.R. Retroviruses human immunodeficiency virus and murine leukemia virus are enriched in phosphoinositides. J. Virol. 2008, 82:11228-11238.
    • (2008) J. Virol. , vol.82 , pp. 11228-11238
    • Chan, R.1    Uchil, P.D.2    Jin, J.3    Shui, G.4    Ott, D.E.5    Mothes, W.6    Wenk, M.R.7
  • 24
    • 0038532298 scopus 로고    scopus 로고
    • A role for ceramide, but not diacylglycerol, in the antagonism of insulin signal transduction by saturated fatty acids
    • Chavez J.A., Knotts T.A., Wang L.P., Li G., Dobrowsky R.T., Florant G.L., Summers S.A. A role for ceramide, but not diacylglycerol, in the antagonism of insulin signal transduction by saturated fatty acids. J. Biol. Chem. 2003, 278:10297-10303.
    • (2003) J. Biol. Chem. , vol.278 , pp. 10297-10303
    • Chavez, J.A.1    Knotts, T.A.2    Wang, L.P.3    Li, G.4    Dobrowsky, R.T.5    Florant, G.L.6    Summers, S.A.7
  • 28
    • 0023860891 scopus 로고
    • Apolipoprotein E polymorphism and atherosclerosis
    • Davignon J., Gregg R.E., Sing C.F. Apolipoprotein E polymorphism and atherosclerosis. Arteriosclerosis 1988, 8:1-21.
    • (1988) Arteriosclerosis , vol.8 , pp. 1-21
    • Davignon, J.1    Gregg, R.E.2    Sing, C.F.3
  • 29
    • 33645236362 scopus 로고    scopus 로고
    • A novel lipase belonging to the hormone-sensitive lipase family induced under starvation to utilize stored triacylglycerol in Mycobacterium tuberculosis
    • Deb C., Daniel J., Sirakova T.D., Abomoelak B., Dubey V.S., Kolattukudy P.E. A novel lipase belonging to the hormone-sensitive lipase family induced under starvation to utilize stored triacylglycerol in Mycobacterium tuberculosis. J. Biol. Chem. 2006, 281:3866-3875.
    • (2006) J. Biol. Chem. , vol.281 , pp. 3866-3875
    • Deb, C.1    Daniel, J.2    Sirakova, T.D.3    Abomoelak, B.4    Dubey, V.S.5    Kolattukudy, P.E.6
  • 32
    • 33749595083 scopus 로고    scopus 로고
    • Lysophosphatidic acid acyltransferase-beta (LPAAT-beta) is highly expressed in advanced ovarian cancer and is associated with aggressive histology and poor survival
    • Diefenbach C.S.M., Soslow R.A., Iasonos A., Linkov I., Hedvat C., Bonham L., Singer J., Barakat R.R., Aghajanian C., Dupont J. Lysophosphatidic acid acyltransferase-beta (LPAAT-beta) is highly expressed in advanced ovarian cancer and is associated with aggressive histology and poor survival. Cancer 2006, 107:1511-1519.
    • (2006) Cancer , vol.107 , pp. 1511-1519
    • Diefenbach, C.S.M.1    Soslow, R.A.2    Iasonos, A.3    Linkov, I.4    Hedvat, C.5    Bonham, L.6    Singer, J.7    Barakat, R.R.8    Aghajanian, C.9    Dupont, J.10
  • 33
    • 0032752261 scopus 로고    scopus 로고
    • Acyltransferases of de novo glycerophospholipid biosynthesis
    • Dircks L., Sul H.S. Acyltransferases of de novo glycerophospholipid biosynthesis. Prog. Lipid Res. 1999, 38:461-479.
    • (1999) Prog. Lipid Res. , vol.38 , pp. 461-479
    • Dircks, L.1    Sul, H.S.2
  • 34
    • 33847747061 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis virulence: lipids inside and out
    • Ehrt S., Schnappinger D. Mycobacterium tuberculosis virulence: lipids inside and out. Nat. Med. 2007, 13:284-285.
    • (2007) Nat. Med. , vol.13 , pp. 284-285
    • Ehrt, S.1    Schnappinger, D.2
  • 36
    • 0036500210 scopus 로고    scopus 로고
    • Quantitative profiling of phospholipids by multiple precursor ion scanning on a hybrid quadrupole time-of-flight mass spectrometer
    • Ekroos K., Chernushevich I.V., Simons K., Shevchenko A. Quantitative profiling of phospholipids by multiple precursor ion scanning on a hybrid quadrupole time-of-flight mass spectrometer. Anal. Chem. 2002, 74:941-949.
    • (2002) Anal. Chem. , vol.74 , pp. 941-949
    • Ekroos, K.1    Chernushevich, I.V.2    Simons, K.3    Shevchenko, A.4
  • 37
    • 77952950642 scopus 로고    scopus 로고
    • Something worth dyeing for: molecular tools for the dissection of lipid metabolism in Caenorhabditis elegans
    • Elle I.C., Olsen L.C.B., Pultz D., Rødkaer S.V., Faergeman N.J. Something worth dyeing for: molecular tools for the dissection of lipid metabolism in Caenorhabditis elegans. FEBS Lett. 2010, 584:2183-2193.
    • (2010) FEBS Lett. , vol.584 , pp. 2183-2193
    • Elle, I.C.1    Olsen, L.C.B.2    Pultz, D.3    Rødkaer, S.V.4    Faergeman, N.J.5
  • 38
    • 78649937107 scopus 로고    scopus 로고
    • Stressed-induced TMEM135 protein is part of a conserved genetic network involved in fat storage and longevity regulation in Caenorhabditis elegans
    • Exil V.J., Silva Avila D., Benedetto A., Exil E.A., Adams M.R., Au C., Aschner M. Stressed-induced TMEM135 protein is part of a conserved genetic network involved in fat storage and longevity regulation in Caenorhabditis elegans. PloS ONE 2010, 5:e14228.
    • (2010) PloS ONE , vol.5
    • Exil, V.J.1    Silva Avila, D.2    Benedetto, A.3    Exil, E.A.4    Adams, M.R.5    Au, C.6    Aschner, M.7
  • 41
    • 84874286934 scopus 로고    scopus 로고
    • Genetically modified pig models for human diseases
    • Fan N., Lai L. Genetically modified pig models for human diseases. J. Genet. Genomics 2013, 40:67-73.
    • (2013) J. Genet. Genomics , vol.40 , pp. 67-73
    • Fan, N.1    Lai, L.2
  • 43
    • 34248220964 scopus 로고    scopus 로고
    • Electrospray mass spectrometry of human hair wax esters
    • Fitzgerald M., Murphy R.C. Electrospray mass spectrometry of human hair wax esters. J. Lipid Res. 2007, 48:1231-1246.
    • (2007) J. Lipid Res. , vol.48 , pp. 1231-1246
    • Fitzgerald, M.1    Murphy, R.C.2
  • 44
    • 0014352063 scopus 로고
    • A colorimetric method for estimating serum triglycerides
    • Fletcher M.J. A colorimetric method for estimating serum triglycerides. Clin. Chim. Acta 1968, 22:393-397.
    • (1968) Clin. Chim. Acta , vol.22 , pp. 393-397
    • Fletcher, M.J.1
  • 45
    • 0033669319 scopus 로고    scopus 로고
    • In situ and invitro study of colocalization and segregation of alpha-synuclein, ubiquitin, and lipids in Lewy bodies
    • Gai W.P., Yuan H.X., Li X.Q., Power J.T., Blumbergs P.C., Jensen P.H. In situ and invitro study of colocalization and segregation of alpha-synuclein, ubiquitin, and lipids in Lewy bodies. Exp. Neurol. 2000, 166:324-333.
    • (2000) Exp. Neurol. , vol.166 , pp. 324-333
    • Gai, W.P.1    Yuan, H.X.2    Li, X.Q.3    Power, J.T.4    Blumbergs, P.C.5    Jensen, P.H.6
  • 47
    • 33746014977 scopus 로고    scopus 로고
    • Non-targeted profiling of lipids during kainate-induced neuronal injury
    • Guan X.L., He X., Ong W.Y., Yeo W.K., Shui G., Wenk M.R. Non-targeted profiling of lipids during kainate-induced neuronal injury. FASEB J. 2006, 20:1152-1161.
    • (2006) FASEB J. , vol.20 , pp. 1152-1161
    • Guan, X.L.1    He, X.2    Ong, W.Y.3    Yeo, W.K.4    Shui, G.5    Wenk, M.R.6
  • 49
    • 33744472183 scopus 로고    scopus 로고
    • Mass spectrometry-based profiling of phospholipids and sphingolipids in extracts from Saccharomyces cerevisiae
    • Guan X.L., Wenk M.R. Mass spectrometry-based profiling of phospholipids and sphingolipids in extracts from Saccharomyces cerevisiae. Yeast 2006, 23:465-477.
    • (2006) Yeast , vol.23 , pp. 465-477
    • Guan, X.L.1    Wenk, M.R.2
  • 51
    • 0025336428 scopus 로고
    • Plasmenylcholine and phosphatidylcholine membrane bilayers possess distinct conformational motifs
    • Han X.L., Gross R.W. Plasmenylcholine and phosphatidylcholine membrane bilayers possess distinct conformational motifs. Biochemistry 1990, 29:4992-4996.
    • (1990) Biochemistry , vol.29 , pp. 4992-4996
    • Han, X.L.1    Gross, R.W.2
  • 52
    • 0026093930 scopus 로고
    • Alterations in membrane dynamics elicited by amphiphilic compounds are augmented in plasmenylcholine bilayers
    • Han X.L., Gross R.W. Alterations in membrane dynamics elicited by amphiphilic compounds are augmented in plasmenylcholine bilayers. Biochim. Biophys. Acta 1991, 1069:37-45.
    • (1991) Biochim. Biophys. Acta , vol.1069 , pp. 37-45
    • Han, X.L.1    Gross, R.W.2
  • 53
    • 0035425057 scopus 로고    scopus 로고
    • Quantitative analysis and molecular species fingerprinting of triacylglyceride molecular species directly from lipid extracts of biological samples by electrospray ionization tandem mass spectrometry
    • Han X., Gross R.W. Quantitative analysis and molecular species fingerprinting of triacylglyceride molecular species directly from lipid extracts of biological samples by electrospray ionization tandem mass spectrometry. Anal. Biochem. 2001, 295:88-100.
    • (2001) Anal. Biochem. , vol.295 , pp. 88-100
    • Han, X.1    Gross, R.W.2
  • 54
    • 0141653274 scopus 로고    scopus 로고
    • Global analyses of cellular lipidomes directly from crude extracts of biological samples by ESI mass spectrometry: a bridge to lipidomics
    • Han X., Gross R.W. Global analyses of cellular lipidomes directly from crude extracts of biological samples by ESI mass spectrometry: a bridge to lipidomics. J. Lipid Res. 2003, 44:1071-1079.
    • (2003) J. Lipid Res. , vol.44 , pp. 1071-1079
    • Han, X.1    Gross, R.W.2
  • 55
    • 38449115897 scopus 로고    scopus 로고
    • Alzheimer's disease: the lipid connection
    • Hartmann T., Kuchenbecker J., Grimm M.O.W. Alzheimer's disease: the lipid connection. J. Neurochem. 2007, 103(Suppl. 1):159-170.
    • (2007) J. Neurochem. , vol.103 , Issue.SUPPL. 1 , pp. 159-170
    • Hartmann, T.1    Kuchenbecker, J.2    Grimm, M.O.W.3
  • 56
    • 16244410140 scopus 로고    scopus 로고
    • Automated quantitative analysis of complex lipidomes by liquid chromatography/mass spectrometry
    • Hermansson M., Uphoff A., Käkelä R., Somerharju P. Automated quantitative analysis of complex lipidomes by liquid chromatography/mass spectrometry. Anal. Chem. 2005, 77:2166-2175.
    • (2005) Anal. Chem. , vol.77 , pp. 2166-2175
    • Hermansson, M.1    Uphoff, A.2    Käkelä, R.3    Somerharju, P.4
  • 59
    • 0034487745 scopus 로고    scopus 로고
    • Characterization of phosphatidylinositol, phosphatidylinositol-4-phosphate, and phosphatidylinositol-4,5-bisphosphate by electrospray ionization tandem mass spectrometry: a mechanistic study
    • Hsu F.F., Turk J. Characterization of phosphatidylinositol, phosphatidylinositol-4-phosphate, and phosphatidylinositol-4,5-bisphosphate by electrospray ionization tandem mass spectrometry: a mechanistic study. J. Am. Soc. Mass Spectrom. 2000, 11:986-999.
    • (2000) J. Am. Soc. Mass Spectrom. , vol.11 , pp. 986-999
    • Hsu, F.F.1    Turk, J.2
  • 60
    • 0037975593 scopus 로고    scopus 로고
    • Electrospray ionization/tandem quadrupole mass spectrometric studies on phosphatidylcholines: the fragmentation processes
    • Hsu F.F., Turk J. Electrospray ionization/tandem quadrupole mass spectrometric studies on phosphatidylcholines: the fragmentation processes. J. Am. Soc. Mass Spectrom. 2003, 14:352-363.
    • (2003) J. Am. Soc. Mass Spectrom. , vol.14 , pp. 352-363
    • Hsu, F.F.1    Turk, J.2
  • 62
    • 77951914765 scopus 로고    scopus 로고
    • Membrane microdomains and insulin resistance
    • Inokuchi J.I. Membrane microdomains and insulin resistance. FEBS Lett. 2010, 584:1864-1871.
    • (2010) FEBS Lett. , vol.584 , pp. 1864-1871
    • Inokuchi, J.I.1
  • 63
  • 64
    • 0028217603 scopus 로고
    • Identification of molecular species of glycerophospholipids and sphingomyelin using electrospray mass spectrometry
    • Kerwin J.L., Tuininga A.R., Ericsson L.H. Identification of molecular species of glycerophospholipids and sphingomyelin using electrospray mass spectrometry. J. Lipid Res. 1994, 35:1102-1114.
    • (1994) J. Lipid Res. , vol.35 , pp. 1102-1114
    • Kerwin, J.L.1    Tuininga, A.R.2    Ericsson, L.H.3
  • 67
    • 69749111026 scopus 로고    scopus 로고
    • Lipidomic analyses of the mouse brain after antidepressant treatment: evidence for endogenous release of long-chain fatty acids?
    • Lee L.H.W., Shui G., Farooqui A.A., Wenk M.R., Tan C.H., Ong W.Y. Lipidomic analyses of the mouse brain after antidepressant treatment: evidence for endogenous release of long-chain fatty acids?. Int. J. Neuropsychopharmacol. 2009, 12:953-964.
    • (2009) Int. J. Neuropsychopharmacol. , vol.12 , pp. 953-964
    • Lee, L.H.W.1    Shui, G.2    Farooqui, A.A.3    Wenk, M.R.4    Tan, C.H.5    Ong, W.Y.6
  • 68
    • 0031106609 scopus 로고    scopus 로고
    • Characterization and quantification of rat bile phosphatidylcholine by electrospray-tandem mass spectrometry
    • Lehmann W.D., Koester M., Erben G., Keppler D. Characterization and quantification of rat bile phosphatidylcholine by electrospray-tandem mass spectrometry. Anal. Biochem. 1997, 246:102-110.
    • (1997) Anal. Biochem. , vol.246 , pp. 102-110
    • Lehmann, W.D.1    Koester, M.2    Erben, G.3    Keppler, D.4
  • 73
    • 67749095757 scopus 로고    scopus 로고
    • Triacylglycerol utilization is required for regrowth of invitro hypoxic nonreplicating Mycobacterium bovis bacillus Calmette-Guerin
    • Low K.L., Rao P.S.S., Shui G., Bendt A.K., Pethe K., Dick T., Wenk M.R. Triacylglycerol utilization is required for regrowth of invitro hypoxic nonreplicating Mycobacterium bovis bacillus Calmette-Guerin. J. Bacteriol. 2009, 191:5037-5043.
    • (2009) J. Bacteriol. , vol.191 , pp. 5037-5043
    • Low, K.L.1    Rao, P.S.S.2    Shui, G.3    Bendt, A.K.4    Pethe, K.5    Dick, T.6    Wenk, M.R.7
  • 74
    • 77954380461 scopus 로고    scopus 로고
    • Lipid droplet-associated proteins are involved in the biosynthesis and hydrolysis of triacylglycerol in Mycobacterium bovis bacillus Calmette-Guerin
    • Low K.L., Shui G., Natter K., Yeo W.K., Kohlwein S.D., Dick T., Rao S.P.S., Wenk M.R. Lipid droplet-associated proteins are involved in the biosynthesis and hydrolysis of triacylglycerol in Mycobacterium bovis bacillus Calmette-Guerin. J. Biol. Chem. 2010, 285:21662-21670.
    • (2010) J. Biol. Chem. , vol.285 , pp. 21662-21670
    • Low, K.L.1    Shui, G.2    Natter, K.3    Yeo, W.K.4    Kohlwein, S.D.5    Dick, T.6    Rao, S.P.S.7    Wenk, M.R.8
  • 76
    • 46449123752 scopus 로고    scopus 로고
    • Mitochondria, body fat and type 2 diabetes: what is the connection?
    • Maasen J.A. Mitochondria, body fat and type 2 diabetes: what is the connection?. Minerva Med. 2008, 99:241-251.
    • (2008) Minerva Med. , vol.99 , pp. 241-251
    • Maasen, J.A.1
  • 80
    • 19444380734 scopus 로고    scopus 로고
    • Sphingolipidomics: high-throughput, structure-specific, and quantitative analysis of sphingolipids by liquid chromatography tandem mass spectrometry
    • Merrill A.H., Sullards M.C., Allegood J.C., Kelly S., Wang E. Sphingolipidomics: high-throughput, structure-specific, and quantitative analysis of sphingolipids by liquid chromatography tandem mass spectrometry. Methods 2005, 36:207-224.
    • (2005) Methods , vol.36 , pp. 207-224
    • Merrill, A.H.1    Sullards, M.C.2    Allegood, J.C.3    Kelly, S.4    Wang, E.5
  • 82
    • 73949130073 scopus 로고    scopus 로고
    • Arabidopsis lipins mediate eukaryotic pathway of lipid metabolism and cope critically with phosphate starvation
    • Nakamura Y., Koizumi R., Shui G., Shimojima M., Wenk M.R., Ito T., Ohta H. Arabidopsis lipins mediate eukaryotic pathway of lipid metabolism and cope critically with phosphate starvation. Proc. Natl. Acad. Sci. USA 2009, 106:20978-20983.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 20978-20983
    • Nakamura, Y.1    Koizumi, R.2    Shui, G.3    Shimojima, M.4    Wenk, M.R.5    Ito, T.6    Ohta, H.7
  • 83
    • 78149442652 scopus 로고    scopus 로고
    • Phosphatidylinositol 5-phosphate links dehydration stress to the activity of ARABIDOPSIS TRITHORAX-LIKE factor ATX1
    • Ndamukong I., Jones D.R., Lapko H., Divecha N., Avramova Z. Phosphatidylinositol 5-phosphate links dehydration stress to the activity of ARABIDOPSIS TRITHORAX-LIKE factor ATX1. PloS ONE 2010, 5:e13396.
    • (2010) PloS ONE , vol.5
    • Ndamukong, I.1    Jones, D.R.2    Lapko, H.3    Divecha, N.4    Avramova, Z.5
  • 85
    • 0034015604 scopus 로고    scopus 로고
    • Evidence for budding of human immunodeficiency virus type 1 selectively from glycolipid-enriched membrane lipid rafts
    • Nguyen D.H., Hildreth J.E. Evidence for budding of human immunodeficiency virus type 1 selectively from glycolipid-enriched membrane lipid rafts. J. Virol. 2000, 74:3264-3272.
    • (2000) J. Virol. , vol.74 , pp. 3264-3272
    • Nguyen, D.H.1    Hildreth, J.E.2
  • 89
    • 26944452885 scopus 로고    scopus 로고
    • Role of lipid rafts in virus replication
    • Ono A., Freed E.O. Role of lipid rafts in virus replication. Adv. Virus Res. 2005, 64:311-358.
    • (2005) Adv. Virus Res. , vol.64 , pp. 311-358
    • Ono, A.1    Freed, E.O.2
  • 90
    • 70350365111 scopus 로고    scopus 로고
    • C. elegans major fats are stored in vesicles distinct from lysosome-related organelles
    • O'Rourke E.J., Soukas A.A., Carr C.E., Ruvkun G. C. elegans major fats are stored in vesicles distinct from lysosome-related organelles. Cell Metab. 2009, 10:430-435.
    • (2009) Cell Metab. , vol.10 , pp. 430-435
    • O'Rourke, E.J.1    Soukas, A.A.2    Carr, C.E.3    Ruvkun, G.4
  • 91
    • 37249016440 scopus 로고    scopus 로고
    • Rapid, standardized method for determination of Mycobacterium tuberculosis drug susceptibility by use of mycolic acid analysis
    • Parrish N., Osterhout G., Dionne K., Sweeney A., Kwiatkowski N., Carroll K., Jost K.C., Dick J. Rapid, standardized method for determination of Mycobacterium tuberculosis drug susceptibility by use of mycolic acid analysis. J. Clin. Microbiol. 2007, 45:3915-3920.
    • (2007) J. Clin. Microbiol. , vol.45 , pp. 3915-3920
    • Parrish, N.1    Osterhout, G.2    Dionne, K.3    Sweeney, A.4    Kwiatkowski, N.5    Carroll, K.6    Jost, K.C.7    Dick, J.8
  • 92
    • 77957796110 scopus 로고    scopus 로고
    • Nonspecific phospholipase C NPC4 promotes responses to abscisic acid and tolerance to hyperosmotic stress in Arabidopsis
    • Peters C., Li M., Narasimhan R., Roth M., Welti R., Wang X. Nonspecific phospholipase C NPC4 promotes responses to abscisic acid and tolerance to hyperosmotic stress in Arabidopsis. Plant Cell 2010, 22:2642-2659.
    • (2010) Plant Cell , vol.22 , pp. 2642-2659
    • Peters, C.1    Li, M.2    Narasimhan, R.3    Roth, M.4    Welti, R.5    Wang, X.6
  • 94
    • 33746085241 scopus 로고    scopus 로고
    • Rafts defined: a report on the Keystone Symposium on Lipid Rafts and Cell Function
    • Pike L.J. Rafts defined: a report on the Keystone Symposium on Lipid Rafts and Cell Function. J. Lipid Res. 2006, 47:1597-1598.
    • (2006) J. Lipid Res. , vol.47 , pp. 1597-1598
    • Pike, L.J.1
  • 95
    • 0141974064 scopus 로고    scopus 로고
    • Electrospray mass spectrometry of phospholipids
    • Pulfer M., Murphy R.C. Electrospray mass spectrometry of phospholipids. Mass Spectrom. Rev. 2003, 22:332-364.
    • (2003) Mass Spectrom. Rev. , vol.22 , pp. 332-364
    • Pulfer, M.1    Murphy, R.C.2
  • 97
    • 17244380947 scopus 로고    scopus 로고
    • Lipid rafts and membrane dynamics
    • Rajendran L., Simons K. Lipid rafts and membrane dynamics. J. Cell Sci. 2005, 118:1099-1102.
    • (2005) J. Cell Sci. , vol.118 , pp. 1099-1102
    • Rajendran, L.1    Simons, K.2
  • 98
    • 70349214775 scopus 로고    scopus 로고
    • Lipidomic profiling in mouse brain reveals differences between ages and genders, with smaller changes associated with α-synuclein genotype
    • Rappley I., Myers D.S., Milne S.B., Ivanova P.T., Lavoie M.J., Brown H.A., Selkoe D.J. Lipidomic profiling in mouse brain reveals differences between ages and genders, with smaller changes associated with α-synuclein genotype. J. Neurochem. 2009, 111:15-25.
    • (2009) J. Neurochem. , vol.111 , pp. 15-25
    • Rappley, I.1    Myers, D.S.2    Milne, S.B.3    Ivanova, P.T.4    Lavoie, M.J.5    Brown, H.A.6    Selkoe, D.J.7
  • 100
    • 77956393934 scopus 로고    scopus 로고
    • Alpha-synuclein, lipids and Parkinson's disease
    • Ruipérez V., Darios F., Davletov B. Alpha-synuclein, lipids and Parkinson's disease. Prog. Lipid Res. 2010, 49:420-428.
    • (2010) Prog. Lipid Res. , vol.49 , pp. 420-428
    • Ruipérez, V.1    Darios, F.2    Davletov, B.3
  • 105
    • 58649098789 scopus 로고    scopus 로고
    • Acyl-CoA:lysophospholipid acyltransferases
    • Shindou H., Shimizu T. Acyl-CoA:lysophospholipid acyltransferases. J. Biol. Chem. 2009, 284:1-5.
    • (2009) J. Biol. Chem. , vol.284 , pp. 1-5
    • Shindou, H.1    Shimizu, T.2
  • 107
    • 34548388923 scopus 로고    scopus 로고
    • Sensitive profiling of chemically diverse bioactive lipids
    • Shui G., Bendt A.K., Pethe K., Dick T., Wenk M.R. Sensitive profiling of chemically diverse bioactive lipids. J. Lipid Res. 2007, 48:1976-1984.
    • (2007) J. Lipid Res. , vol.48 , pp. 1976-1984
    • Shui, G.1    Bendt, A.K.2    Pethe, K.3    Dick, T.4    Wenk, M.R.5
  • 108
    • 77957814983 scopus 로고    scopus 로고
    • Characterization of substrate preference for Slc1p and Cst26p in Saccharomyces cerevisiae using lipidomic approaches and an LPAAT activity assay
    • Shui G., Guan X.L., Gopalakrishnan P., Xue Y., Goh J.S.Y., Yang H., Wenk M.R. Characterization of substrate preference for Slc1p and Cst26p in Saccharomyces cerevisiae using lipidomic approaches and an LPAAT activity assay. PloS ONE 2010, 5:e11956.
    • (2010) PloS ONE , vol.5
    • Shui, G.1    Guan, X.L.2    Gopalakrishnan, P.3    Xue, Y.4    Goh, J.S.Y.5    Yang, H.6    Wenk, M.R.7
  • 109
    • 77952512222 scopus 로고    scopus 로고
    • Toward one step analysis of cellular lipidomes using liquid chromatography coupled with mass spectrometry: application to Saccharomyces cerevisiae and Schizosaccharomyces pombe lipidomics
    • Shui G., Guan X.L., Low C.P., Chua G.H., Goh J.S.Y., Yang H., Wenk M.R. Toward one step analysis of cellular lipidomes using liquid chromatography coupled with mass spectrometry: application to Saccharomyces cerevisiae and Schizosaccharomyces pombe lipidomics. Mol. Biosyst. 2010, 6:1008-1017.
    • (2010) Mol. Biosyst. , vol.6 , pp. 1008-1017
    • Shui, G.1    Guan, X.L.2    Low, C.P.3    Chua, G.H.4    Goh, J.S.Y.5    Yang, H.6    Wenk, M.R.7
  • 110
    • 84880615621 scopus 로고    scopus 로고
    • Polar lipid derangements in type 2 diabetes mellitus: potential pathological relevance of fatty acyl heterogeneity in sphingolipids
    • Shui G., Lam S.M., Stebbins J., Kusunoki J., Duan X., Li B., Cheong W.F., Soon D., Kelly R.P., Wenk M.R. Polar lipid derangements in type 2 diabetes mellitus: potential pathological relevance of fatty acyl heterogeneity in sphingolipids. Metabolomics 2013, 9:786-799.
    • (2013) Metabolomics , vol.9 , pp. 786-799
    • Shui, G.1    Lam, S.M.2    Stebbins, J.3    Kusunoki, J.4    Duan, X.5    Li, B.6    Cheong, W.F.7    Soon, D.8    Kelly, R.P.9    Wenk, M.R.10
  • 114
    • 2542533903 scopus 로고    scopus 로고
    • Metabolomic profiling of sphingolipids in human glioma cell lines by liquid chromatography tandem mass spectrometry
    • Sullards M.C., Wang E., Peng Q., Merrill A.H. Metabolomic profiling of sphingolipids in human glioma cell lines by liquid chromatography tandem mass spectrometry. Cell. Mol. Biol. (Noisy-le-grand) 2003, 49:789-797.
    • (2003) Cell. Mol. Biol. (Noisy-le-grand) , vol.49 , pp. 789-797
    • Sullards, M.C.1    Wang, E.2    Peng, Q.3    Merrill, A.H.4
  • 115
    • 79955629359 scopus 로고    scopus 로고
    • Tissue-autonomous function of Drosophila seipin in preventing ectopic lipid droplet formation
    • Tian Y., Bi J., Shui G., Liu Z., Xiang Y., Liu Y., Wenk M.R., Yang H., Huang X. Tissue-autonomous function of Drosophila seipin in preventing ectopic lipid droplet formation. PLoS Genet. 2011, 7:e1001364.
    • (2011) PLoS Genet. , vol.7
    • Tian, Y.1    Bi, J.2    Shui, G.3    Liu, Z.4    Xiang, Y.5    Liu, Y.6    Wenk, M.R.7    Yang, H.8    Huang, X.9
  • 116
    • 71849083577 scopus 로고    scopus 로고
    • Lipids in host-pathogen interactions: pathogens exploit the complexity of the host cell lipidome
    • van der Meer-Janssen Y.P.M., van Galen J., Batenburg J.J., Helms J.B. Lipids in host-pathogen interactions: pathogens exploit the complexity of the host cell lipidome. Prog. Lipid Res. 2010, 49:1-26.
    • (2010) Prog. Lipid Res. , vol.49 , pp. 1-26
    • van der Meer-Janssen, Y.P.M.1    van Galen, J.2    Batenburg, J.J.3    Helms, J.B.4
  • 118
    • 25144443228 scopus 로고    scopus 로고
    • Cellular lipidomics
    • van Meer G. Cellular lipidomics. EMBO J. 2005, 24:3159-3165.
    • (2005) EMBO J. , vol.24 , pp. 3159-3165
    • van Meer, G.1
  • 120
    • 0034780485 scopus 로고    scopus 로고
    • Nonreplicating persistence of mycobacterium tuberculosis
    • Wayne L.G., Sohaskey C.D. Nonreplicating persistence of mycobacterium tuberculosis. Annu. Rev. Microbiol. 2001, 55:139-163.
    • (2001) Annu. Rev. Microbiol. , vol.55 , pp. 139-163
    • Wayne, L.G.1    Sohaskey, C.D.2
  • 121
    • 2442617114 scopus 로고    scopus 로고
    • Lipid species profiling: a high-throughput approach to identify lipid compositional changes and determine the function of genes involved in lipid metabolism and signaling
    • Welti R., Wang X. Lipid species profiling: a high-throughput approach to identify lipid compositional changes and determine the function of genes involved in lipid metabolism and signaling. Curr. Opin. Plant Biol. 2004, 7:337-344.
    • (2004) Curr. Opin. Plant Biol. , vol.7 , pp. 337-344
    • Welti, R.1    Wang, X.2
  • 122
    • 22144478635 scopus 로고    scopus 로고
    • The emerging field of lipidomics
    • Wenk M.R. The emerging field of lipidomics. Nat. Rev. Drug Discov. 2005, 4:594-610.
    • (2005) Nat. Rev. Drug Discov. , vol.4 , pp. 594-610
    • Wenk, M.R.1
  • 123
    • 33749051854 scopus 로고    scopus 로고
    • Lipidomics of host-pathogen interactions
    • Wenk M.R. Lipidomics of host-pathogen interactions. FEBS Lett. 2006, 580:5541-5551.
    • (2006) FEBS Lett. , vol.580 , pp. 5541-5551
    • Wenk, M.R.1
  • 124
    • 2342466734 scopus 로고    scopus 로고
    • Global prevalence of diabetes: estimates for the year 2000 and projections for 2030
    • Wild S., Roglic G., Green A., Sicree R., King H. Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care 2004, 27:1047-1053.
    • (2004) Diabetes Care , vol.27 , pp. 1047-1053
    • Wild, S.1    Roglic, G.2    Green, A.3    Sicree, R.4    King, H.5
  • 126
    • 66349116161 scopus 로고    scopus 로고
    • Automated lipid identification and quantification by multidimensional mass spectrometry-based shotgun lipidomics
    • Yang K., Cheng H., Gross R.W., Han X. Automated lipid identification and quantification by multidimensional mass spectrometry-based shotgun lipidomics. Anal. Chem. 2009, 81:4356-4368.
    • (2009) Anal. Chem. , vol.81 , pp. 4356-4368
    • Yang, K.1    Cheng, H.2    Gross, R.W.3    Han, X.4
  • 128
    • 77958586133 scopus 로고    scopus 로고
    • A comparative study of fat storage quantitation in nematode Caenorhabditis elegans using label and label-free methods
    • Yen K., Le T.T., Bansal A., Narasimhan S.D., Cheng J.X., Tissenbaum H.A. A comparative study of fat storage quantitation in nematode Caenorhabditis elegans using label and label-free methods. PloS ONE 2010, 5:e12810.
    • (2010) PloS ONE , vol.5
    • Yen, K.1    Le, T.T.2    Bansal, A.3    Narasimhan, S.D.4    Cheng, J.X.5    Tissenbaum, H.A.6
  • 129
    • 38549111882 scopus 로고    scopus 로고
    • Informatics and computational strategies for the study of lipids
    • Yetukuri L., Ekroos K., Vidal-Puig A., Oresic M. Informatics and computational strategies for the study of lipids. Mol. Biosyst. 2008, 4:121-127.
    • (2008) Mol. Biosyst. , vol.4 , pp. 121-127
    • Yetukuri, L.1    Ekroos, K.2    Vidal-Puig, A.3    Oresic, M.4
  • 130
    • 2942750349 scopus 로고    scopus 로고
    • Loss of plastidic lysophosphatidic acid acyltransferase causes embryo-lethality in Arabidopsis
    • Yu B., Wakao S., Fan J., Benning C. Loss of plastidic lysophosphatidic acid acyltransferase causes embryo-lethality in Arabidopsis. Plant Cell Physiol. 2004, 45:503-510.
    • (2004) Plant Cell Physiol. , vol.45 , pp. 503-510
    • Yu, B.1    Wakao, S.2    Fan, J.3    Benning, C.4
  • 131
    • 34248228704 scopus 로고    scopus 로고
    • Inhibiting glycosphingolipid synthesis improves glycemic control and insulin sensitivity in animal models of type 2 diabetes
    • Zhao H., Przybylska M., Wu I.H., Zhang J., Siegel C., Komarnitsky S., Yew N.S., Cheng S.H. Inhibiting glycosphingolipid synthesis improves glycemic control and insulin sensitivity in animal models of type 2 diabetes. Diabetes 2007, 56:1210-1218.
    • (2007) Diabetes , vol.56 , pp. 1210-1218
    • Zhao, H.1    Przybylska, M.2    Wu, I.H.3    Zhang, J.4    Siegel, C.5    Komarnitsky, S.6    Yew, N.S.7    Cheng, S.H.8
  • 132
    • 0035834657 scopus 로고    scopus 로고
    • The initial step of the glycerolipid pathway: identification of glycerol 3-phosphate/dihydroxyacetone phosphate dual substrate acyltransferases in Saccharomyces cerevisiae
    • Zheng Z., Zou J. The initial step of the glycerolipid pathway: identification of glycerol 3-phosphate/dihydroxyacetone phosphate dual substrate acyltransferases in Saccharomyces cerevisiae. J. Biol. Chem. 2001, 276:41710-41716.
    • (2001) J. Biol. Chem. , vol.276 , pp. 41710-41716
    • Zheng, Z.1    Zou, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.