-
1
-
-
77955635233
-
Cancer statistics, 2010
-
Jemal A, Siegel R, Xu J, Ward E, (2010) Cancer statistics, 2010. CA: A Cancer Journal for Clinicians 60: 277-300.
-
(2010)
CA: A Cancer Journal for Clinicians
, vol.60
, pp. 277-300
-
-
Jemal, A.1
Siegel, R.2
Xu, J.3
Ward, E.4
-
3
-
-
0038481970
-
The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited
-
Fidler IJ, (2003) The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited. Nature Reviews Cancer 3: 453-458.
-
(2003)
Nature Reviews Cancer
, vol.3
, pp. 453-458
-
-
Fidler, I.J.1
-
4
-
-
47549090432
-
TGFbeta in Cancer
-
Massagué J, (2008) TGFbeta in Cancer. Cell 134: 215-230.
-
(2008)
Cell
, vol.134
, pp. 215-230
-
-
Massagué, J.1
-
7
-
-
0026646785
-
Endoglin is a component of the transforming growth factor-beta receptor system in human endothelial cells
-
Cheifetz S, Bellón T, Calés C, Vera S, Bernabeu C, et al. (1992) Endoglin is a component of the transforming growth factor-beta receptor system in human endothelial cells. The Journal of Biological Chemistry 267: 19027-19030.
-
(1992)
The Journal of Biological Chemistry
, vol.267
, pp. 19027-19030
-
-
Cheifetz, S.1
Bellón, T.2
Calés, C.3
Vera, S.4
Bernabeu, C.5
-
8
-
-
15844419905
-
Endoglin modulates cellular responses to TGF-beta 1
-
Lastres P, Letamendía A, Zhang H, Rius C, Almendro N, et al. (1996) Endoglin modulates cellular responses to TGF-beta 1. The Journal of Cell Biology 133: 1109-1121.
-
(1996)
The Journal of Cell Biology
, vol.133
, pp. 1109-1121
-
-
Lastres, P.1
Letamendía, A.2
Zhang, H.3
Rius, C.4
Almendro, N.5
-
9
-
-
0032484022
-
Role of endoglin in cellular responses to transforming growth factor-beta. A comparative study with betaglycan
-
Letamendía A, Lastres P, Botella LM, Raab U, Langa C, et al. (1998) Role of endoglin in cellular responses to transforming growth factor-beta. A comparative study with betaglycan. The Journal of Biological Chemistry 273: 33011-33019.
-
(1998)
The Journal of Biological Chemistry
, vol.273
, pp. 33011-33019
-
-
Letamendía, A.1
Lastres, P.2
Botella, L.M.3
Raab, U.4
Langa, C.5
-
10
-
-
0037007226
-
Balancing the activation state of the endothelium via two distinct TGF-beta type I receptors
-
Goumans M-J, Valdimarsdottir G, Itoh S, Rosendahl A, Sideras P, et al. (2002) Balancing the activation state of the endothelium via two distinct TGF-beta type I receptors. The EMBO Journal 21: 1743-1753.
-
(2002)
The EMBO Journal
, vol.21
, pp. 1743-1753
-
-
Goumans, M.-J.1
Valdimarsdottir, G.2
Itoh, S.3
Rosendahl, A.4
Sideras, P.5
-
11
-
-
0242330126
-
Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFbeta/ALK5 signaling
-
Goumans MJ, Valdimarsdottir G, Itoh S, Lebrin F, Larsson J, et al. (2003) Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFbeta/ALK5 signaling. Molecular Cell 12: 817-828.
-
(2003)
Molecular Cell
, vol.12
, pp. 817-828
-
-
Goumans, M.J.1
Valdimarsdottir, G.2
Itoh, S.3
Lebrin, F.4
Larsson, J.5
-
12
-
-
21644452716
-
Interaction and functional interplay between endoglin and ALK-1, two components of the endothelial transforming growth factor-beta receptor complex
-
Blanco FJ, Santibanez JF, Guerrero-Esteo M, Langa C, Vary CPH, et al. (2005) Interaction and functional interplay between endoglin and ALK-1, two components of the endothelial transforming growth factor-beta receptor complex. Journal of Cellular Physiology 204: 574-584.
-
(2005)
Journal of Cellular Physiology
, vol.204
, pp. 574-584
-
-
Blanco, F.J.1
Santibanez, J.F.2
Guerrero-Esteo, M.3
Langa, C.4
Vary, C.P.H.5
-
13
-
-
34347230515
-
Endoglin differentially modulates antagonistic transforming growth factor-beta1 and BMP-7 signaling
-
Scherner O, Meurer SK, Tihaa L, Gressner AM, Weiskirchen R, (2007) Endoglin differentially modulates antagonistic transforming growth factor-beta1 and BMP-7 signaling. The Journal of Biological Chemistry 282: 13934-13943.
-
(2007)
The Journal of Biological Chemistry
, vol.282
, pp. 13934-13943
-
-
Scherner, O.1
Meurer, S.K.2
Tihaa, L.3
Gressner, A.M.4
Weiskirchen, R.5
-
14
-
-
36048973196
-
Endoglin inhibits prostate cancer motility via activation of the ALK2-Smad1 pathway
-
Craft CS, Romero D, Vary CPH, Bergan RC, (2007) Endoglin inhibits prostate cancer motility via activation of the ALK2-Smad1 pathway. Oncogene 26: 7240-7250.
-
(2007)
Oncogene
, vol.26
, pp. 7240-7250
-
-
Craft, C.S.1
Romero, D.2
Vary, C.P.H.3
Bergan, R.C.4
-
15
-
-
3042589327
-
Endoglin controls cell migration and composition of focal adhesions: function of the cytosolic domain
-
Conley BA, Koleva R, Smith JD, Kacer D, Zhang D, et al. (2004) Endoglin controls cell migration and composition of focal adhesions: function of the cytosolic domain. The Journal of Biological Chemistry 279: 27440-27449.
-
(2004)
The Journal of Biological Chemistry
, vol.279
, pp. 27440-27449
-
-
Conley, B.A.1
Koleva, R.2
Smith, J.D.3
Kacer, D.4
Zhang, D.5
-
16
-
-
3543041235
-
Endoglin regulates cytoskeletal organization through binding to ZRP-1, a member of the Lim family of proteins
-
Sanz-Rodriguez F, Guerrero-Esteo M, Botella L-M, Banville D, Vary CPH, et al. (2004) Endoglin regulates cytoskeletal organization through binding to ZRP-1, a member of the Lim family of proteins. The Journal of Biological Chemistry 279: 32858-32868.
-
(2004)
The Journal of Biological Chemistry
, vol.279
, pp. 32858-32868
-
-
Sanz-Rodriguez, F.1
Guerrero-Esteo, M.2
Botella, L.-M.3
Banville, D.4
Vary, C.P.H.5
-
17
-
-
24144490843
-
CEACAM engagement by human pathogens enhances cell adhesion and counteracts bacteria-induced detachment of epithelial cells
-
Muenzner P, Rohde M, Kneitz S, Hauck CR, (2005) CEACAM engagement by human pathogens enhances cell adhesion and counteracts bacteria-induced detachment of epithelial cells. The Journal of Cell Biology 170: 825-836.
-
(2005)
The Journal of Cell Biology
, vol.170
, pp. 825-836
-
-
Muenzner, P.1
Rohde, M.2
Kneitz, S.3
Hauck, C.R.4
-
18
-
-
77956296581
-
Human-restricted bacterial pathogens block shedding of epithelial cells by stimulating integrin activation
-
Muenzner P, Bachmann V, Zimmermann W, Hentschel J, Hauck CR, (2010) Human-restricted bacterial pathogens block shedding of epithelial cells by stimulating integrin activation. Science (New York, NY) 329: 1197-1201.
-
(2010)
Science (New York, NY)
, vol.329
, pp. 1197-1201
-
-
Muenzner, P.1
Bachmann, V.2
Zimmermann, W.3
Hentschel, J.4
Hauck, C.R.5
-
19
-
-
78751644361
-
Critical role of endoglin in tumor cell plasticity of Ewing sarcoma and melanoma
-
Pardali E, van der Schaft DWJ, Wiercinska E, Gorter A, Hogendoorn PCW, et al. (2011) Critical role of endoglin in tumor cell plasticity of Ewing sarcoma and melanoma. Oncogene 30: 334-345.
-
(2011)
Oncogene
, vol.30
, pp. 334-345
-
-
Pardali, E.1
van der Schaft, D.W.J.2
Wiercinska, E.3
Gorter, A.4
Hogendoorn, P.C.W.5
-
20
-
-
79960239007
-
SPARC promotes pericyte recruitment via inhibition of endoglin-dependent TGF-β1 activity
-
Rivera LB, Brekken RA, (2011) SPARC promotes pericyte recruitment via inhibition of endoglin-dependent TGF-β1 activity. The Journal of Cell Biology 193: 1305-1319.
-
(2011)
The Journal of Cell Biology
, vol.193
, pp. 1305-1319
-
-
Rivera, L.B.1
Brekken, R.A.2
-
21
-
-
84867101901
-
Endoglin mediates fibronectin/α5β1 integrin and TGF-β pathway crosstalk in endothelial cells
-
Tian H, Mythreye K, Golzio C, Katsanis N, Blobe GC, (2012) Endoglin mediates fibronectin/α5β1 integrin and TGF-β pathway crosstalk in endothelial cells. The EMBO journal 31: 3885-3900.
-
(2012)
The EMBO Journal
, vol.31
, pp. 3885-3900
-
-
Tian, H.1
Mythreye, K.2
Golzio, C.3
Katsanis, N.4
Blobe, G.C.5
-
22
-
-
78649785000
-
The TGF-beta co-receptor endoglin modulates the expression and transforming potential of H-Ras
-
Santibanez JF, Pérez-Gómez E, Fernandez-L A, Garrido-Martin EM, Carnero A, et al. (2010) The TGF-beta co-receptor endoglin modulates the expression and transforming potential of H-Ras. Carcinogenesis 31: 2145-2154.
-
(2010)
Carcinogenesis
, vol.31
, pp. 2145-2154
-
-
Santibanez, J.F.1
Pérez-Gómez, E.2
Fernandez-L, A.3
Garrido-Martin, E.M.4
Carnero, A.5
-
24
-
-
78650255998
-
The role of the TGF-β coreceptor endoglin in cancer
-
Pérez-Gómez E, Del Castillo G, Juan Francisco S, López-Novoa JM, Bernabéu C, et al. (2010) The role of the TGF-β coreceptor endoglin in cancer. TheScientificWorldJournal 10: 2367-2384.
-
(2010)
TheScientificWorldJournal
, vol.10
, pp. 2367-2384
-
-
Pérez-Gómez, E.1
Del Castillo, G.2
Juan Francisco, S.3
López-Novoa, J.M.4
Bernabéu, C.5
-
25
-
-
0028171579
-
Endoglin, a TGF-beta binding protein of endothelial cells, is the gene for hereditary haemorrhagic telangiectasia type 1
-
McAllister KA, Grogg KM, Johnson DW, Gallione CJ, Baldwin MA, et al. (1994) Endoglin, a TGF-beta binding protein of endothelial cells, is the gene for hereditary haemorrhagic telangiectasia type 1. Nature Genetics 8: 345-351.
-
(1994)
Nature Genetics
, vol.8
, pp. 345-351
-
-
McAllister, K.A.1
Grogg, K.M.2
Johnson, D.W.3
Gallione, C.J.4
Baldwin, M.A.5
-
26
-
-
12344273467
-
TGF-beta receptor function in the endothelium
-
Lebrin F, Deckers M, Bertolino P, Ten Dijke P, (2005) TGF-beta receptor function in the endothelium. Cardiovascular Research 65: 599-608.
-
(2005)
Cardiovascular Research
, vol.65
, pp. 599-608
-
-
Lebrin, F.1
Deckers, M.2
Bertolino, P.3
Ten Dijke, P.4
-
27
-
-
0036591699
-
Endoglin (CD105) is expressed on immature blood vessels and is a marker for survival in prostate cancer
-
Wikström P, Lissbrant IF, Stattin P, Egevad L, Bergh A, (2002) Endoglin (CD105) is expressed on immature blood vessels and is a marker for survival in prostate cancer. The Prostate 51: 268-275.
-
(2002)
The Prostate
, vol.51
, pp. 268-275
-
-
Wikström, P.1
Lissbrant, I.F.2
Stattin, P.3
Egevad, L.4
Bergh, A.5
-
28
-
-
34247104610
-
Endoglin (CD105) and vascular endothelial growth factor as prognostic markers in prostatic adenocarcinoma
-
El-Gohary YM, Silverman JF, Olson PR, Liu YL, Cohen JK, et al. (2007) Endoglin (CD105) and vascular endothelial growth factor as prognostic markers in prostatic adenocarcinoma. American Journal of Clinical Pathology 127: 572-579.
-
(2007)
American Journal of Clinical Pathology
, vol.127
, pp. 572-579
-
-
El-Gohary, Y.M.1
Silverman, J.F.2
Olson, P.R.3
Liu, Y.L.4
Cohen, J.K.5
-
29
-
-
79956101964
-
Endoglin regulates cancer-stromal cell interactions in prostate tumors
-
Romero D, O'Neill C, Terzic A, Contois L, Young K, et al. (2011) Endoglin regulates cancer-stromal cell interactions in prostate tumors. Cancer Res 71: 3482-3493.
-
(2011)
Cancer Res
, vol.71
, pp. 3482-3493
-
-
Romero, D.1
O'Neill, C.2
Terzic, A.3
Contois, L.4
Young, K.5
-
30
-
-
3142766904
-
Whole-mount prostate sections reveal differential endoglin expression in stromal, epithelial, and endothelial cells with the development of prostate cancer
-
Kassouf W, Ismail HRA, Aprikian AG, Chevalier S, (2004) Whole-mount prostate sections reveal differential endoglin expression in stromal, epithelial, and endothelial cells with the development of prostate cancer. Prostate Cancer and Prostatic Diseases 7: 105-110.
-
(2004)
Prostate Cancer and Prostatic Diseases
, vol.7
, pp. 105-110
-
-
Kassouf, W.1
Ismail, H.R.A.2
Aprikian, A.G.3
Chevalier, S.4
-
31
-
-
18744362140
-
Over expression of endoglin in human prostate cancer suppresses cell detachment, migration and invasion
-
Liu Y, Jovanovic B, Pins M, Lee C, Bergan RC, (2002) Over expression of endoglin in human prostate cancer suppresses cell detachment, migration and invasion. Oncogene 21: 8272-8281.
-
(2002)
Oncogene
, vol.21
, pp. 8272-8281
-
-
Liu, Y.1
Jovanovic, B.2
Pins, M.3
Lee, C.4
Bergan, R.C.5
-
32
-
-
37349064255
-
Genistein induces phenotypic reversion of endoglin deficiency in human prostate cancer cells
-
Craft CS, Xu L, Romero D, Vary CPH, Bergan RC, (2008) Genistein induces phenotypic reversion of endoglin deficiency in human prostate cancer cells. Molecular Pharmacology 73: 235-242.
-
(2008)
Molecular Pharmacology
, vol.73
, pp. 235-242
-
-
Craft, C.S.1
Xu, L.2
Romero, D.3
Vary, C.P.H.4
Bergan, R.C.5
-
33
-
-
79951676729
-
Endoglin suppresses human prostate cancer metastasis
-
Lakshman M, Huang X, Ananthanarayanan V, Jovanovic B, Liu Y, et al. (2011) Endoglin suppresses human prostate cancer metastasis. Clinical & Experimental Metastasis 28: 39-53.
-
(2011)
Clinical & Experimental Metastasis
, vol.28
, pp. 39-53
-
-
Lakshman, M.1
Huang, X.2
Ananthanarayanan, V.3
Jovanovic, B.4
Liu, Y.5
-
34
-
-
40949129259
-
Dietary genistein inhibits metastasis of human prostate cancer in mice
-
Lakshman M, Xu L, Ananthanarayanan V, Cooper J, Takimoto CH, et al. (2008) Dietary genistein inhibits metastasis of human prostate cancer in mice. Cancer Research 68: 2024-2032.
-
(2008)
Cancer Research
, vol.68
, pp. 2024-2032
-
-
Lakshman, M.1
Xu, L.2
Ananthanarayanan, V.3
Cooper, J.4
Takimoto, C.H.5
-
35
-
-
77955358312
-
Cell Line Verification Test Recommendations
-
ATCC
-
ATCC (2007) Cell Line Verification Test Recommendations. ATCC Technical Bulletin No. 8: 1-3.
-
(2007)
ATCC Technical Bulletin
, vol.8
, pp. 1-3
-
-
-
36
-
-
69249083967
-
MEK4 function, genistein treatment, and invasion of human prostate cancer cells
-
Xu L, Ding Y, Catalona WJ, Yang XJ, Anderson WF, et al. (2009) MEK4 function, genistein treatment, and invasion of human prostate cancer cells. Journal of the National Cancer Institute 101: 1141-1155.
-
(2009)
Journal of the National Cancer Institute
, vol.101
, pp. 1141-1155
-
-
Xu, L.1
Ding, Y.2
Catalona, W.J.3
Yang, X.J.4
Anderson, W.F.5
-
37
-
-
0026527384
-
Novel activin receptors: distinct genes and alternative mRNA splicing generate a repertoire of serine/threonine kinase receptors
-
Attisano L, Wrana JL, Cheifetz S, Massagué J, (1992) Novel activin receptors: distinct genes and alternative mRNA splicing generate a repertoire of serine/threonine kinase receptors. Cell 68: 97-108.
-
(1992)
Cell
, vol.68
, pp. 97-108
-
-
Attisano, L.1
Wrana, J.L.2
Cheifetz, S.3
Massagué, J.4
-
38
-
-
0034603078
-
Identification of a binding site on the type II activin receptor for activin and inhibin
-
Gray PC, Greenwald J, Blount AL, Kunitake KS, Donaldson CJ, et al. (2000) Identification of a binding site on the type II activin receptor for activin and inhibin. The Journal of biological chemistry 275: 3206-3212.
-
(2000)
The Journal of Biological Chemistry
, vol.275
, pp. 3206-3212
-
-
Gray, P.C.1
Greenwald, J.2
Blount, A.L.3
Kunitake, K.S.4
Donaldson, C.J.5
-
39
-
-
11244313831
-
Activation of LIMK1 by binding to the BMP receptor, BMPRII, regulates BMP-dependent dendritogenesis
-
Lee-Hoeflich ST, Causing CG, Podkowa M, Zhao X, Wrana JL, et al. (2004) Activation of LIMK1 by binding to the BMP receptor, BMPRII, regulates BMP-dependent dendritogenesis. The EMBO Journal 23: 4792-4801.
-
(2004)
The EMBO Journal
, vol.23
, pp. 4792-4801
-
-
Lee-Hoeflich, S.T.1
Causing, C.G.2
Podkowa, M.3
Zhao, X.4
Wrana, J.L.5
-
40
-
-
0037085441
-
Identification and functional characterization of distinct critically important bone morphogenetic protein-specific response elements in the Id1 promoter
-
Korchynskyi O, ten Dijke P, (2002) Identification and functional characterization of distinct critically important bone morphogenetic protein-specific response elements in the Id1 promoter. The Journal of Biological Chemistry 277: 4883-4891.
-
(2002)
The Journal of Biological Chemistry
, vol.277
, pp. 4883-4891
-
-
Korchynskyi, O.1
ten Dijke, P.2
-
41
-
-
17144426480
-
Genistein inhibits p38 map kinase activation, matrix metalloproteinase type 2, and cell invasion in human prostate epithelial cells
-
Huang X, Chen S, Xu L, Liu Y, Deb DK, et al. (2005) Genistein inhibits p38 map kinase activation, matrix metalloproteinase type 2, and cell invasion in human prostate epithelial cells. Cancer Research 65: 3470-3478.
-
(2005)
Cancer Research
, vol.65
, pp. 3470-3478
-
-
Huang, X.1
Chen, S.2
Xu, L.3
Liu, Y.4
Deb, D.K.5
-
42
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
-
Livak KJ, Schmittgen TD, (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25: 402-408.
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
43
-
-
0043068003
-
p38 MAP kinase modulates Smad-dependent changes in human prostate cell adhesion
-
Hayes SA, Huang X, Kambhampati S, Platanias LC, Bergan RC, (2003) p38 MAP kinase modulates Smad-dependent changes in human prostate cell adhesion. Oncogene 22: 4841-4850.
-
(2003)
Oncogene
, vol.22
, pp. 4841-4850
-
-
Hayes, S.A.1
Huang, X.2
Kambhampati, S.3
Platanias, L.C.4
Bergan, R.C.5
-
44
-
-
0033534572
-
Endoglin is an accessory protein that interacts with the signaling receptor complex of multiple members of the transforming growth factor-beta superfamily
-
Barbara NP, Wrana JL, Letarte M, (1999) Endoglin is an accessory protein that interacts with the signaling receptor complex of multiple members of the transforming growth factor-beta superfamily. The Journal of Biological Chemistry 274: 584-594.
-
(1999)
The Journal of Biological Chemistry
, vol.274
, pp. 584-594
-
-
Barbara, N.P.1
Wrana, J.L.2
Letarte, M.3
-
45
-
-
37349064255
-
Genistein induces phenotypic reversion of endoglin deficiency in human prostate cancer cells
-
Craft CS, Xu L, Romero D, Vary CP, Bergan RC, (2008) Genistein induces phenotypic reversion of endoglin deficiency in human prostate cancer cells. Mol Pharmacol 73: 235-242.
-
(2008)
Mol Pharmacol
, vol.73
, pp. 235-242
-
-
Craft, C.S.1
Xu, L.2
Romero, D.3
Vary, C.P.4
Bergan, R.C.5
-
46
-
-
7044221776
-
Loss of expression of bone morphogenetic protein receptor type II in human prostate cancer cells
-
Kim IY, Lee D-H, Lee DK, Ahn H-J, Kim MM, et al. (2004) Loss of expression of bone morphogenetic protein receptor type II in human prostate cancer cells. Oncogene 23: 7651-7659.
-
(2004)
Oncogene
, vol.23
, pp. 7651-7659
-
-
Kim, I.Y.1
Lee, D.-H.2
Lee, D.K.3
Ahn, H.-J.4
Kim, M.M.5
-
47
-
-
77955629240
-
Role of bone morphogenetic proteins in human prostate cancer pathogenesis and development of bone metastases: immunohistochemical study
-
Spanjol J, Djordjević G, Markić D, Klarić M, Fuckar D, et al. (2010) Role of bone morphogenetic proteins in human prostate cancer pathogenesis and development of bone metastases: immunohistochemical study. Collegium Antropologicum 34Suppl 2: 119-125.
-
(2010)
Collegium Antropologicum
, vol.34
, pp. 119-125
-
-
Spanjol, J.1
Djordjević, G.2
Markić, D.3
Klarić, M.4
Fuckar, D.5
-
49
-
-
21644447416
-
Bone morphogenetic protein (BMP) type II receptor deletion reveals BMP ligand-specific gain of signaling in pulmonary artery smooth muscle cells
-
Yu PB, Beppu H, Kawai N, Li E, Bloch KD, (2005) Bone morphogenetic protein (BMP) type II receptor deletion reveals BMP ligand-specific gain of signaling in pulmonary artery smooth muscle cells. The Journal of Biological Chemistry 280: 24443-24450.
-
(2005)
The Journal of Biological Chemistry
, vol.280
, pp. 24443-24450
-
-
Yu, P.B.1
Beppu, H.2
Kawai, N.3
Li, E.4
Bloch, K.D.5
-
50
-
-
0037047426
-
Extracellular and cytoplasmic domains of endoglin interact with the transforming growth factor-beta receptors I and II
-
Guerrero-Esteo M, Sanchez-Elsner T, Letamendia A, Bernabeu C, (2002) Extracellular and cytoplasmic domains of endoglin interact with the transforming growth factor-beta receptors I and II. The Journal of Biological Chemistry 277: 29197-29209.
-
(2002)
The Journal of Biological Chemistry
, vol.277
, pp. 29197-29209
-
-
Guerrero-Esteo, M.1
Sanchez-Elsner, T.2
Letamendia, A.3
Bernabeu, C.4
-
51
-
-
77949526904
-
ActRIIA and BMPRII Type II BMP Receptor Subunits Selectively Required for Smad4-Independent BMP7-Evoked Chemotaxis
-
Perron JC, Dodd J (2009) ActRIIA and BMPRII Type II BMP Receptor Subunits Selectively Required for Smad4-Independent BMP7-Evoked Chemotaxis. PLoS ONE 4.
-
(2009)
PLoS ONE
, vol.4
-
-
Perron, J.C.1
Dodd, J.2
-
52
-
-
27644572195
-
Bone Morphogenetic Protein Receptor Type II C-Terminus Interacts with c-Src: Implication for a Role in Pulmonary Arterial Hypertension
-
Wong WKP, Knowles JA, Morse JH, (2005) Bone Morphogenetic Protein Receptor Type II C-Terminus Interacts with c-Src: Implication for a Role in Pulmonary Arterial Hypertension. Am J Respir Cell Mol Biol 33: 438-446.
-
(2005)
Am J Respir Cell Mol Biol
, vol.33
, pp. 438-446
-
-
Wong, W.K.P.1
Knowles, J.A.2
Morse, J.H.3
-
53
-
-
57049159708
-
Mice expressing BMPR2R899X transgene in smooth muscle develop pulmonary vascular lesions
-
West J, Harral J, Lane K, Deng Y, Ickes B, et al. (2008) Mice expressing BMPR2R899X transgene in smooth muscle develop pulmonary vascular lesions. American Journal of Physiology Lung Cellular and Molecular Physiology 295: L744-755-L744-755.
-
(2008)
American Journal of Physiology Lung Cellular and Molecular Physiology
, vol.295
-
-
West, J.1
Harral, J.2
Lane, K.3
Deng, Y.4
Ickes, B.5
-
54
-
-
2342486700
-
Pulmonary hypertension in transgenic mice expressing a dominant-negative BMPRII gene in smooth muscle
-
West J, Fagan K, Steudel W, Fouty B, Lane K, et al. (2004) Pulmonary hypertension in transgenic mice expressing a dominant-negative BMPRII gene in smooth muscle. Circulation research 94: 1109-1114.
-
(2004)
Circulation Research
, vol.94
, pp. 1109-1114
-
-
West, J.1
Fagan, K.2
Steudel, W.3
Fouty, B.4
Lane, K.5
-
55
-
-
8644256840
-
BMPR-II heterozygous mice have mild pulmonary hypertension and an impaired pulmonary vascular remodeling response to prolonged hypoxia
-
Beppu H, Ichinose F, Kawai N, Jones RC, Yu PB, et al. (2004) BMPR-II heterozygous mice have mild pulmonary hypertension and an impaired pulmonary vascular remodeling response to prolonged hypoxia. American Journal of Physiology- Lung Cellular and Molecular Physiology 287: L1241-L1247.
-
(2004)
American Journal of Physiology - Lung Cellular and Molecular Physiology
, vol.287
-
-
Beppu, H.1
Ichinose, F.2
Kawai, N.3
Jones, R.C.4
Yu, P.B.5
-
56
-
-
0033838125
-
Familial primary pulmonary hypertension (gene PPH1) is caused by mutations in the bone morphogenetic protein receptor-II gene
-
Deng Z, Morse JH, Slager SL, Cuervo N, Moore KJ, et al. (2000) Familial primary pulmonary hypertension (gene PPH1) is caused by mutations in the bone morphogenetic protein receptor-II gene. American Journal of Human Genetics 67: 737-744.
-
(2000)
American Journal of Human Genetics
, vol.67
, pp. 737-744
-
-
Deng, Z.1
Morse, J.H.2
Slager, S.L.3
Cuervo, N.4
Moore, K.J.5
-
57
-
-
0033817459
-
Heterozygous germline mutations in BMPR2, encoding a TGF-beta receptor, cause familial primary pulmonary hypertension
-
Lane KB, Machado RD, Pauciulo MW, Thomson JR, Phillips JA, (2000) Heterozygous germline mutations in BMPR2, encoding a TGF-beta receptor, cause familial primary pulmonary hypertension. Nature Genetics 26: 81-84.
-
(2000)
Nature Genetics
, vol.26
, pp. 81-84
-
-
Lane, K.B.1
Machado, R.D.2
Pauciulo, M.W.3
Thomson, J.R.4
Phillips, J.A.5
-
58
-
-
0033623296
-
Sporadic primary pulmonary hypertension is associated with germline mutations of the gene encoding BMPR-II, a receptor member of the TGF-beta family
-
Thomson JR, Machado RD, Pauciulo MW, Morgan NV, Humbert M, et al. (2000) Sporadic primary pulmonary hypertension is associated with germline mutations of the gene encoding BMPR-II, a receptor member of the TGF-beta family. Journal of Medical Genetics 37: 741-745.
-
(2000)
Journal of Medical Genetics
, vol.37
, pp. 741-745
-
-
Thomson, J.R.1
Machado, R.D.2
Pauciulo, M.W.3
Morgan, N.V.4
Humbert, M.5
-
59
-
-
0037096836
-
Functional analysis of bone morphogenetic protein type II receptor mutations underlying primary pulmonary hypertension
-
Rudarakanchana N, Flanagan JA, Chen H, Upton PD, Machado R, et al. (2002) Functional analysis of bone morphogenetic protein type II receptor mutations underlying primary pulmonary hypertension. Human Molecular Genetics 11: 1517-1525.
-
(2002)
Human Molecular Genetics
, vol.11
, pp. 1517-1525
-
-
Rudarakanchana, N.1
Flanagan, J.A.2
Chen, H.3
Upton, P.D.4
Machado, R.5
-
60
-
-
0036735752
-
Functional heterogeneity of bone morphogenetic protein receptor-II mutants found in patients with primary pulmonary hypertension
-
Nishihara A, Watabe T, Imamura T, Miyazono K, (2002) Functional heterogeneity of bone morphogenetic protein receptor-II mutants found in patients with primary pulmonary hypertension. Molecular Biology of the Cell 13: 3055-3063.
-
(2002)
Molecular Biology of the Cell
, vol.13
, pp. 3055-3063
-
-
Nishihara, A.1
Watabe, T.2
Imamura, T.3
Miyazono, K.4
-
61
-
-
34547882714
-
A novel regulatory mechanism of the bone morphogenetic protein (BMP) signaling pathway involving the carboxyl-terminal tail domain of BMP type II receptor
-
Chan MC, Nguyen PH, Davis BN, Ohoka N, Hayashi H, et al. (2007) A novel regulatory mechanism of the bone morphogenetic protein (BMP) signaling pathway involving the carboxyl-terminal tail domain of BMP type II receptor. Molecular and Cellular Biology 27: 5776-5789.
-
(2007)
Molecular and Cellular Biology
, vol.27
, pp. 5776-5789
-
-
Chan, M.C.1
Nguyen, P.H.2
Davis, B.N.3
Ohoka, N.4
Hayashi, H.5
-
62
-
-
67349167022
-
Novel crosstalk to BMP signalling: cGMP-dependent kinase I modulates BMP receptor and Smad activity
-
Schwappacher R, Weiske J, Heining E, Ezerski V, Marom B, et al. (2009) Novel crosstalk to BMP signalling: cGMP-dependent kinase I modulates BMP receptor and Smad activity. The EMBO Journal 28: 1537-1550.
-
(2009)
The EMBO Journal
, vol.28
, pp. 1537-1550
-
-
Schwappacher, R.1
Weiske, J.2
Heining, E.3
Ezerski, V.4
Marom, B.5
-
63
-
-
0348013127
-
Functional interaction between BMPR-II and Tctex-1, a light chain of Dynein, is isoform-specific and disrupted by mutations underlying primary pulmonary hypertension
-
Machado RD, Rudarakanchana N, Atkinson C, Flanagan JA, Harrison R, et al. (2003) Functional interaction between BMPR-II and Tctex-1, a light chain of Dynein, is isoform-specific and disrupted by mutations underlying primary pulmonary hypertension. Human Molecular Genetics 12: 3277-3286.
-
(2003)
Human Molecular Genetics
, vol.12
, pp. 3277-3286
-
-
Machado, R.D.1
Rudarakanchana, N.2
Atkinson, C.3
Flanagan, J.A.4
Harrison, R.5
-
64
-
-
0141656297
-
Direct signaling by the BMP type II receptor via the cytoskeletal regulator LIMK1
-
Foletta VC, Lim MA, Soosairajah J, Kelly AP, Stanley EG, et al. (2003) Direct signaling by the BMP type II receptor via the cytoskeletal regulator LIMK1. The Journal of Cell Biology 162: 1089-1098.
-
(2003)
The Journal of Cell Biology
, vol.162
, pp. 1089-1098
-
-
Foletta, V.C.1
Lim, M.A.2
Soosairajah, J.3
Kelly, A.P.4
Stanley, E.G.5
-
65
-
-
67649834590
-
The four-and-a-half LIM domain protein 2 regulates vascular smooth muscle phenotype and vascular tone
-
Neuman NA, Ma S, Schnitzler GR, Zhu Y, Lagna G, et al. (2009) The four-and-a-half LIM domain protein 2 regulates vascular smooth muscle phenotype and vascular tone. The Journal of Biological Chemistry 284: 13202-13212.
-
(2009)
The Journal of Biological Chemistry
, vol.284
, pp. 13202-13212
-
-
Neuman, N.A.1
Ma, S.2
Schnitzler, G.R.3
Zhu, Y.4
Lagna, G.5
-
66
-
-
33845981092
-
Identification of Tctex2beta, a novel dynein light chain family member that interacts with different transforming growth factor-beta receptors
-
Meng Q, Lux A, Holloschi A, Li J, Hughes JMX, et al. (2006) Identification of Tctex2beta, a novel dynein light chain family member that interacts with different transforming growth factor-beta receptors. The Journal of Biological Chemistry 281: 37069-37080.
-
(2006)
The Journal of Biological Chemistry
, vol.281
, pp. 37069-37080
-
-
Meng, Q.1
Lux, A.2
Holloschi, A.3
Li, J.4
Hughes, J.M.X.5
-
67
-
-
70649083092
-
Recent advances in BMP receptor signaling
-
Sieber C, Kopf J, Hiepen C, Knaus P, (2009) Recent advances in BMP receptor signaling. Cytokine & Growth Factor Reviews 20: 343-355.
-
(2009)
Cytokine & Growth Factor Reviews
, vol.20
, pp. 343-355
-
-
Sieber, C.1
Kopf, J.2
Hiepen, C.3
Knaus, P.4
-
69
-
-
33847369980
-
Identification of BMP9 and BMP10 as functional activators of the orphan activin receptor-like kinase 1 (ALK1) in endothelial cells
-
David L, Mallet C, Mazerbourg S, Feige J-J, Bailly S, (2007) Identification of BMP9 and BMP10 as functional activators of the orphan activin receptor-like kinase 1 (ALK1) in endothelial cells. Blood 109: 1953-1961.
-
(2007)
Blood
, vol.109
, pp. 1953-1961
-
-
David, L.1
Mallet, C.2
Mazerbourg, S.3
Feige, J.-J.4
Bailly, S.5
-
70
-
-
42949178711
-
Bone morphogenetic protein (BMP) type II receptor is required for BMP-mediated growth arrest and differentiation in pulmonary artery smooth muscle cells
-
Yu PB, Deng DY, Beppu H, Hong CC, Lai C, et al. (2008) Bone morphogenetic protein (BMP) type II receptor is required for BMP-mediated growth arrest and differentiation in pulmonary artery smooth muscle cells. The Journal of Biological Chemistry 283: 3877-3888.
-
(2008)
The Journal of Biological Chemistry
, vol.283
, pp. 3877-3888
-
-
Yu, P.B.1
Deng, D.Y.2
Beppu, H.3
Hong, C.C.4
Lai, C.5
-
71
-
-
21344467705
-
Diverse biological effect and Smad signaling of bone morphogenetic protein 7 in prostate tumor cells
-
Yang S, Zhong C, Frenkel B, Reddi AH, Roy-Burman P, (2005) Diverse biological effect and Smad signaling of bone morphogenetic protein 7 in prostate tumor cells. Cancer Research 65: 5769-5777.
-
(2005)
Cancer Research
, vol.65
, pp. 5769-5777
-
-
Yang, S.1
Zhong, C.2
Frenkel, B.3
Reddi, A.H.4
Roy-Burman, P.5
-
72
-
-
31544464054
-
Overexpression of noggin inhibits BMP-mediated growth of osteolytic prostate cancer lesions
-
Feeley BT, Krenek L, Liu N, Hsu WK, Gamradt SC, et al. (2006) Overexpression of noggin inhibits BMP-mediated growth of osteolytic prostate cancer lesions. Bone 38: 154-166.
-
(2006)
Bone
, vol.38
, pp. 154-166
-
-
Feeley, B.T.1
Krenek, L.2
Liu, N.3
Hsu, W.K.4
Gamradt, S.C.5
-
73
-
-
34250663063
-
Proinvasive activity of BMP-7 through SMAD4/src-independent and ERK/Rac/JNK-dependent signaling pathways in colon cancer cells
-
Grijelmo C, Rodrigue C, Svrcek M, Bruyneel E, Hendrix A, et al. (2007) Proinvasive activity of BMP-7 through SMAD4/src-independent and ERK/Rac/JNK-dependent signaling pathways in colon cancer cells. Cellular Signalling 19: 1722-1732.
-
(2007)
Cellular Signalling
, vol.19
, pp. 1722-1732
-
-
Grijelmo, C.1
Rodrigue, C.2
Svrcek, M.3
Bruyneel, E.4
Hendrix, A.5
-
74
-
-
54549102135
-
Bone morphogenetic protein signaling enhances invasion and bone metastasis of breast cancer cells through Smad pathway
-
Katsuno Y, Hanyu A, Kanda H, Ishikawa Y, Akiyama F, et al. (2008) Bone morphogenetic protein signaling enhances invasion and bone metastasis of breast cancer cells through Smad pathway. Oncogene 27: 6322-6333.
-
(2008)
Oncogene
, vol.27
, pp. 6322-6333
-
-
Katsuno, Y.1
Hanyu, A.2
Kanda, H.3
Ishikawa, Y.4
Akiyama, F.5
-
75
-
-
38949083841
-
BMP-6 over-expression in prostate cancer is associated with increased Id-1 protein and a more invasive phenotype
-
Darby S, Cross S, Brown N, Hamdy F, Robson C, (2008) BMP-6 over-expression in prostate cancer is associated with increased Id-1 protein and a more invasive phenotype. The Journal of Pathology 214: 394-404.
-
(2008)
The Journal of Pathology
, vol.214
, pp. 394-404
-
-
Darby, S.1
Cross, S.2
Brown, N.3
Hamdy, F.4
Robson, C.5
-
76
-
-
34548705794
-
BMP7, a Putative Regulator of Epithelial Homeostasis in the Human Prostate, Is a Potent Inhibitor of Prostate Cancer Bone Metastasis in Vivo
-
Buijs JT, Rentsch CA, van der Horst G, van Overveld PGM, Wetterwald A, et al. (2007) BMP7, a Putative Regulator of Epithelial Homeostasis in the Human Prostate, Is a Potent Inhibitor of Prostate Cancer Bone Metastasis in Vivo. Am J Pathol 171: 1047-1057.
-
(2007)
Am J Pathol
, vol.171
, pp. 1047-1057
-
-
Buijs, J.T.1
Rentsch, C.A.2
van der Horst, G.3
van Overveld, P.G.M.4
Wetterwald, A.5
-
77
-
-
54249167904
-
Bone morphogenetic protein-9 induces apoptosis in prostate cancer cells, the role of prostate apoptosis response-4
-
Ye L, Kynaston H, Jiang WG, (2008) Bone morphogenetic protein-9 induces apoptosis in prostate cancer cells, the role of prostate apoptosis response-4. Molecular Cancer Research: MCR 6: 1594-1606.
-
(2008)
Molecular Cancer Research: MCR
, vol.6
, pp. 1594-1606
-
-
Ye, L.1
Kynaston, H.2
Jiang, W.G.3
-
78
-
-
67349283960
-
Bone morphogenetic protein-10 suppresses the growth and aggressiveness of prostate cancer cells through a Smad independent pathway
-
Ye L, Kynaston H, Jiang WG, (2009) Bone morphogenetic protein-10 suppresses the growth and aggressiveness of prostate cancer cells through a Smad independent pathway. The Journal of Urology 181: 2749-2759.
-
(2009)
The Journal of Urology
, vol.181
, pp. 2749-2759
-
-
Ye, L.1
Kynaston, H.2
Jiang, W.G.3
-
79
-
-
84857407558
-
Disruption of bone morphogenetic protein receptor 2 (BMPR2) in mammary tumors promotes metastases through cell autonomous and paracrine mediators
-
Owens P, Pickup MW, Novitskiy SV, Chytil A, Gorska AE, et al. (2012) Disruption of bone morphogenetic protein receptor 2 (BMPR2) in mammary tumors promotes metastases through cell autonomous and paracrine mediators. Proceedings of the National Academy of Sciences of the United States of America 109: 2814-2819.
-
(2012)
Proceedings of the National Academy of Sciences of the United States of America
, vol.109
, pp. 2814-2819
-
-
Owens, P.1
Pickup, M.W.2
Novitskiy, S.V.3
Chytil, A.4
Gorska, A.E.5
-
80
-
-
77957021763
-
Bone morphogenetic protein-10 (BMP-10) inhibits aggressiveness of breast cancer cells and correlates with poor prognosis in breast cancer
-
Ye L, Bokobza S, Li J, Moazzam M, Chen J, et al. (2010) Bone morphogenetic protein-10 (BMP-10) inhibits aggressiveness of breast cancer cells and correlates with poor prognosis in breast cancer. Cancer Science 101: 2137-2144.
-
(2010)
Cancer Science
, vol.101
, pp. 2137-2144
-
-
Ye, L.1
Bokobza, S.2
Li, J.3
Moazzam, M.4
Chen, J.5
-
81
-
-
79956101964
-
Endoglin regulates cancer-stromal cell interactions in prostate tumors
-
Romero D, O'Neill C, Terzic A, Contois L, Young K, et al. (2011) Endoglin regulates cancer-stromal cell interactions in prostate tumors. Cancer research 71: 3482-3493.
-
(2011)
Cancer Research
, vol.71
, pp. 3482-3493
-
-
Romero, D.1
O'Neill, C.2
Terzic, A.3
Contois, L.4
Young, K.5
-
82
-
-
84881490558
-
Endoglin phosphorylation by ALK2 contributes to the regulation of prostate cancer cell migration
-
Romero D, Terzic A, Conley BA, Craft C, Jovanovic B, et al. (2009) Endoglin phosphorylation by ALK2 contributes to the regulation of prostate cancer cell migration. Carcinogenesis.
-
(2009)
Carcinogenesis
-
-
Romero, D.1
Terzic, A.2
Conley, B.A.3
Craft, C.4
Jovanovic, B.5
|