Disruption of bone morphogenetic protein receptor 2 (BMPR2) in mammary tumors promotes metastases through cell autonomous and paracrine mediators

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 8, 2012, Pages 2814-2819

  Owens, Philip ^a   Pickup, Michael W ^a   Novitskiy, Sergey V ^a   Chytil, Anna ^a   Gorska, Agnieszka E ^a   Aakre, Mary E ^a   West, James ^b   Moses, Harold L ^a  

^a VANDERBILT INGRAM CANCER CENTER   (United States)

^b VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN RECEPTOR 2; CCL9 CHEMOKINE; CHEMOKINE; DOXYCYCLINE; UNCLASSIFIED DRUG; VIRUS MIDDLE T ANTIGEN;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; BREAST EPITHELIUM; BREAST TUMOR; CANCER GROWTH; CANCER INVASION; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE RELEASE; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INFLAMMATORY CELL; LUNG METASTASIS; MALE; METASTASIS; MOUSE; MOUSE MAMMARY TUMOR ONCOVIRUS; NONHUMAN; PARACRINE SIGNALING; PRIORITY JOURNAL; PROMOTER REGION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; STROMA; SUPPRESSOR CELL; TUMOR CELL; TUMOR MICROENVIRONMENT; TUMOR SUPPRESSOR GENE;

ANIMALS; ANTIGENS, POLYOMAVIRUS TRANSFORMING; BONE MORPHOGENETIC PROTEIN RECEPTORS, TYPE II; CELL MOVEMENT; CELL PROLIFERATION; CHEMOKINES; DISEASE PROGRESSION; FEMALE; HUMANS; INFLAMMATION; MAMMARY GLANDS, ANIMAL; MAMMARY NEOPLASMS, ANIMAL; MAMMARY TUMOR VIRUS, MOUSE; MICE; MYELOID CELLS; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; NEOVASCULARIZATION, PATHOLOGIC; PARACRINE COMMUNICATION; SIGNAL TRANSDUCTION; TUMOR MICROENVIRONMENT;

EID: 84857407558     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1101139108     Document Type: Article

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